... engaging? DESIGNER I can t wait for the next great gaming experience! GAMER ARe YOU MOBILE ARe YOU CASUAL ARe YOU AVID How can I use gaming to make my product more engaging? DESIGNER (or anyone ... purpose and 4) meaningful mastery - Jane McGonigal gamification extrinsic motivators intrinsic motivators “extrinsic motivators may lead “People are best motivated to merely short-range activity ... http://en.wikipedia.org/wiki/Hype_cycle http://meta.gamify.com/ How I make boring stuff fun? FLASH HTML5 gamification SEO SOCIAL WEB 2.0 gamification “the use of game play mechanics for non-game applications, particularly consumer-oriented...
... required to organize a chain of water molecules in the active site of chorismate synthase, which form a proton relay system among the isoalloxazine ring of FMN, His106 and substrate This proton relay ... oxalate (1 mm), 50 mm Mops, pH 7 .5, and enzyme (1. 25 lm for the wild-type and Ser127Ala mutant proteins or 12 .5 lm of the Ser16Ala and Ser16AlaSer127Ala mutant proteins) Chorismate formation was ... where we used photoreduction to generate the reduced flavin cofactor In the absence of oxygen, the rate of chorismate formation was six- and 70-fold lower for the Ser127Ala and Ser16Ala mutant proteins,...
... adherence to treatment is important toensure optimal outcomes Identifying accurate predictors of adherence thatcan routinely be applied in clinical practice will beof value Currently available approaches ... relevant financial relationships Vasanthapuram Kumaraswami, MD, PhD, has disclosed no relevant financial relationships Soumya Swaminathan, MD, DNB, has disclosed no relevant financial relationships ... combination of viral and host factors that facilitate the emergence of HIV variants with resistance to multiple antiretroviral drugs The emergence of drug resistance in patients receiving HAART can...
... of data could probably be improved if standard rules for recording infestations are established Foresters could also be trained to use appropriate symptoms for the identification of attacks and ... there really were When the date of marking was compared to the stage of the attacks, it was observed that trees were often marked only when attacks became detectable from a distance, when the bark ... only to scientists but to forest managers as well Providing that limitations are clearly established, sales of infested timber could provide a rapid and cost-effective way to estimate past and...
... thirds of the requested diary data [28] "The combination of SMS data collection and a traditional Web page for data display and system customization may bea better and more usable tool for patients ... basis ofa minimum use ofa certain time period per month fora year Potential customers have to provide proof ofa regular income, sign a contract, and have a bank account and a permanent address ... lifetime ofa patient One advantage of telephones to manage chronic disease is its ability to create a two-way interaction between patient and provider(s) and thus facilitate the dynamic nature of...
... remains tobe determined Indeed, the characterization of responders and non-responders isa key issue A 15% increase in cardiac output is usually considered tobe significant and isusedto characterize ... separating responders and non-responders was similar to values reported in the literature [2 ,5, 9], it is likely that this 15% cutoff value was adequate However, it is quite evident that the cutoff ... may be lower when at least five boluses are averaged), hence a 15% (7% + 7%, rounded to 15% ) difference between two measurements is required toensurethat the difference is real and cannot be...
... important than others and these canbe emphasized in the radar diagrams through a weighting process The values thatcanbe ascribed to indicators that are most readily monetized are then compared quantitatively ... trajectory for the GMS as a whole An implication of this isthat comparative advantage cannot be assumed in building hydropower projects in the Lao PDR, for example, relative to Thailand as regards ... available only for existing plants in Viet Nam due to the availability of the database supplied by the Load Dispatch Centre of Electricity Vietnam National The data made available included many...
... Confidence, and a love of the media and current affairs are important too It’s a definite advantage if people can show they have a dedicated interest in PR, either through a post-graduate diploma in ... extra-curricular work at university.” Siobhan Abernathy, Board Director, Nexus Choat “The key quality we are looking for in graduates is hunger Hunger to learn, to develop, to thrive We also ... he/she came from isa big advantage Know the company’s mission statement and any reasons it may have been in the news recently Also research the company’s clients, and the industries it specialises...
... Like The Beatles but now I never listen to them (Tôi thích nhóm The Beatles không nghe nhạc họ n a. ) 2- He usedto have long hair but nowadays this hair is very short (Anh ta để tóc dài dạo anh để ... a) Thói quen khứ: You usedto something, ngh a bạn làm việc khoảng thời gian khứ, bạn không làm việc Ex: 1- We usedto live there when I as a child (Chúng sống đ a trẻ.) 2- I usedto walk to ... câu hỏi Used to: Did(n’t) + subject + use to Ex: Did he use to work in the office very late at night? (Anh ta có thường hay làm việc văn phòng trễ vào buổi tối không?) Dạng phủ định Used to: Subject...
... reflecting major organ function; CT scans of the chest, abdomen, and pelvis; and a bone marrow biopsy Neither a positron emission tomography (PET) scan nor a gallium scan is absolutely necessary for ... primary staging, but one performed at the completion of therapy allows evaluation of persisting radiographic abnormalities, particularly the mediastinum Knowing that the PET scan or gallium scan ... electrophoresis are often included in the evaluation Anatomic stage is assigned in the same manner as usedfor Hodgkin's disease However, the prognosis of patients with non-Hodgkin's lymphoma is best assigned...
... studies were in Asia (Nepal, India, Pakistan, Thailand), Africa (Egypt, Malawi, Mozambique, South Africa) and South America (Argentina and Columbia) Characteristic problems related to infection ... Welfare 1997, 43:1-4 13 Rajaram P, Agrawal A, Swain S: Determinants of maternal mortality: a hospital-based study from South India Indian Journal of Maternal and Child Health 19 95, 6:7-10 14 Belizán ... lack of standardisation and methodological rigour of the studies constrained any conclusions [48] A study in India showed that care for longer stay, hospital acquired bacteraemia in a cardiac...
... Clinical data looking at the increase in mean arterial pressure after noradrenaline (norepinephrine) administration [7] show that there isa greater response to noradrenaline in patients with normal ... have a complication was the study conducted by Briegel and colleagues [9] Patients developed hyponatraemia and increased alanine aminotransferase levels at day 14 The hyponatraemia was probably ... Med 19 95, 23: 1294-1303 Cronin L, Cook DJ, Carlet J, Heyland DK, King D, Lansang MA, Fisher CJ Jr: Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature...
... these patients appear tobe low due to hypoproteinemia Their free cortisol levels seem tobe preserved and may in fact be elevated There are several important limitations of this study that deserve ... cortisol is difficult and expensive and not widely available Finally, no standard levels of free cortisol have been reported, so the definition of abnormal for this parameter remains uncertain ... total cortisol levels in the presence of hypoproteinemia It shows that up to 39% of patients with low albumin levels would be misdiagnosed as being adrenally insufficient based on total cortisol...
... Journal of Agricultural and Food Chemistry 20 05, 53 :8706-8713 Weangsripanaval T, Moriyama T, Kageura T, Ogawa T, Kawada T: Dietary fat and an exogenous emulsifier increase the gastrointestinal absorption ... SE: Passage of undegraded dietary antigen into the blood of healthy adults Further characterization of the kinetics of uptake and the size distribution of the antigen Scandinavian Journal of Immunology ... Thomas K, Aalbers M, Bannon GA, Bartels M, Dearman RJ, Esdaile DJ, Fu TJ, Glatt CM, Hadfield N, Hatzos C, et al.: A multi-laboratory evaluation ofa common in vitro pepsin digestion assay protocol...
... contains a cluster of CDK consensus matches, as well as a nuclear localization signal [39] As an illustration ofa potential mechanistic basis for this model, consider the case of clusters of ... suggest that this is also consistent with the hypothesis of combinato- Methodology reports It is also important to note that there are additional possible biological explanations for the large numbers ... proteins Additional data files The following additional data are available with the online version of this paper Additional data file contains the S cerevisiae proteins with SLR above 3 .5, and the...
... studies of sulfasalazine usedfor the treatment of RA have been published, based on the available data, even if there isa risk associated with sulfasalazine, it is likely tobe very low However, because ... 19:219-232 Toma H, Tanabe K, Tokumoto T, Kobayashi C, Yagisawa T: Pregnancy in women receiving renal dialysis or transplantation in Japan: a nationwide survey Nephrol Dial Transplant1999, 14: 151 1- 151 6 ... data for most medications, the quality of human data thatis available is limited Retrospective adverse event or case reports lack denominator information and cannot demonstrate an excess risk...
... (I’m not) Asian people tend to find this much easier, as squatting isa natural way to rest in many parts of Asia It’s a natural position and very conducive to relaxation, meditation and palming, ... again to become the new background Keep repeating this exercise until you get a background so black that you can t imagine a globe any blacker Green Palming The Taoist Masters teach us that "green" ... to regain the natural ability to focus upon the Macula The macula is at the centre of the retina where the incoming rays of light are focused The macula is very important and is responsible for: ...
... standard curve was usedto quantify the amplified DNA The sequences of the primers used are as follows: LTR forward, 5 -GCC TCA ATA AAG CTT GCC TTG A- 3’; and LTR reverse, 5 -TCC ACA CTG ACT AAA ... (5 -(FAM)-ACA CTA CTT GAA GCA CTC AAG GCA AGC TTT-(TAMRA)-3’) [27] All reactions were performed in a volume of 20 μl containing 1× TaqMan Universal Master Mix, No AmpErase UNG, and 200 nM of forward ... using a Qiagen Miniprep kit To identify 2-LTR circle formation, primers MH5 35 (5 -AAC TAG GGA ACC CAC TGC TTA AG-3’) and MH536 (5 -TCC ACA GAT CAA GGA TAT CTT GTC-3’) were used with the MH603 probe...