ischemia reperfusion injury and hyperbaric oxygen therapy basic mechanisms and clinical studies
báo cáo khoa học: " The impact of hyperbaric oxygen therapy on serological values of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)" pptx
... L: The historical perspective of hyperbaric therapy Ann N Y Acad Sci 1965, 117:651-670 Camporesi RM: Hyperbaric oxygen therapy: A Committee Report Undersea and Hyperbaric Medical Society Kensington ... immunoassays and drafted the manuscript, KW and SJ participated in the design of the study and performed the statistical analysis HP and JK conceived of the study, and participated in its design and coordination ... and neurons, bFGF is involved in many physiological and pathophysiological processes like growth, wound and bone healing, cell differentiation and proliferation, but also tumour progression and...
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Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt
... groups and 3, and significantly lower in group than in group at 24 h and 72 h after IR injury On the other hand, this protein expression was markedly lower in group than in groups and 3, and notably ... in group than in groups and 3, and notably lower in Figure Histopathological scoring of ischemia- reperfusion (IR)-induced renal injury H & E staining (200 × in A, B & C and 400 × in D, E & F) ... cells, and cells of embryonic origins, the ethical issue regarding the source and safety of allo- and xeno-grafting has become important concern in the clinical setting On the other hand, the...
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Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt
... Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page ... tranduced into myocardium and protected against myocardial ischemiareperfusion injury in rats [12,14] To examine the combined effect of PEP-1-SOD1 and PEP-1-CAT, we applied both of PEP-1-SOD1 and ... myocardial ischemia- reperfusion injury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and cTnT are reliable indicators of myocardium injury...
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Báo cáo y học: "Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery" pptx
... rewiring, and pectoralis or rectus muscle and omental flap rotation [21-23] HBO2 therapy might offer additional biochemical and cellular effects With the administration of HBO2 therapy, the partial oxygen ... Anderson J, Hanson D, Thompson P: Hyperbaric Oxygen Therapy for Chronic Wounds Adv Skin Wound Care 2010, 23(3):116-119 Cimşit M, Uzun G, Yildiz S: Hyperbaric oxygen therapy as an anti-infective agent ... the administration of HBO2 therapy has theoretical benefit for these patients However, there are only few case reports and non-randomized studies about the use of HBO2 therapy in this patient population...
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Báo cáo y học: "Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method" doc
... method for sciatic nerve ischemia- reperfusion injury Microsurg 2007, 27(3):206-207 Iida H, Schmelzer JD, Schmeichel AN, et al.: Peripheral nerve ischemia: reperfusion injury and fiber degeneration ... aforementioned studies showing IFD and profound axonal edema at days Iida [4] also reported a third phase of fiber regeneration with only minimal edema and fiber debris at 28 and 42 days of reperfusion; ... of peripheral nerve of rats from ischaemia -reperfusion injury Brain 1999, 122(Pt 1):161-169 Saray A, Can B, Akbiyik F, et al.: Ischemia- Reperfusion injury of the peripheral nerve: an experimental...
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Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx
... during ischemia- reperfusion injury This drug and its trihydrate form is a pro-drug that is dephosphorylated in tissues to a pharmacologically active free thiol Clinical pharmacokinetic studies ... (Ca-1) and at the end of the experiment (Ca-8) It's noticed a decrease in Ca levels of 5.5% and 8% in (I) and (II) groups and 25% in (III) (animals 13 to 18) with antimutagenic, anticlastogenic and ... neuronal cell death and paraplegia in the rabbit model of spinal cord ischemia J Thorac Cardiovasc Surg 2001, 122:136-143 Hall ED: The role of oxygen radicals in traumatic injury: clinical implications...
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Báo cáo y học: "CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice" docx
... despite very strong preclinical data [16] In an effort to understand the disparity between the preclinical and clinical trial studies, it was noted that the lengths of injury in the clinical setting ... liver injury following hepatic ischemia/ reperfusion in the rat Hepatology 1996, 23:506 Jaeschke H, Farhood A: Neutrophil and Kupffer cell-induced oxidant stress and ischemia- reperfusion injury ... subjected to 90 minutes of ischemia followed by and 15 h of reperfusion respectively; (D and F) P/I null mouse subjected to 90 minutes of ischemia followed by and 15 h of reperfusion, respectively...
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Báo cáo y học: "Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice" potx
... point in each group were studied Ischemia- reperfusion of the LAD An open-chest model of I/R using ligation and reperfusion of the LAD was modified from Michael and colleagues [36] Mice were anesthetized ... 63.48 ± 2.9%, and 65.47 ± 2.4% in arginine vasopressin (AVP; n = 14), normal saline solution (SL; n = 9), and dobutamine (DOB; n = 6), resepctively Following ischemia/ reperfusion (I/R) injury, AVP ... Holmes CL, Landry DW, Granton JT: Science Review: Vasopressin and the cardiovascular system part – clinical physiology Crit Care 2004, 8:15-23 Landry DW, Levin HR, Gallant EM, Seo S, D'Alessandro D,...
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Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx
... short ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemia and ... McMarron PD: Reperfusion nerve injury pathology due to reflow and prolonged ischemia J Peripher Nerv Syst 1997, 2(1):60-69 Carden DL, Granger DN: Pathophysiology of ischemia- reperfusion injury J ... Plexus and Peripheral Nerve Injury 2006, 1:2 http://www.JBPPNI.com/content/1/1/2 ischemia surgery for the MDA measurements and histopathological studies, respectively Neuropathology: edema and axonal...
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báo cáo khoa học: "Computed tomography colonography imaging of pneumatosis intestinalis after hyperbaric oxygen therapy: a case report" docx
... daily [7] Inhalation oxygen therapy was first introduced in the early in order to increase the partial pressure of oxygen in the blood and to decrease the partial pressure of non -oxygen gases in the ... inappropriate surgery may worsen PI and deteriorate the general condition of the patient [6] Conclusions Treatment options for PI include antibiotics, diet therapy, oxygen therapy and more invasive techniques ... success of inhalation oxygen therapy, but the optimal amount and duration of such treatment to induce cyst deflation is not known HBO2 is also successful in treating PI and has the major advantage...
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Báo cáo y học: " Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" ppt
... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 targeted therapy Clin ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...
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Báo cáo y học: " tài: Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" potx
... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 targeted therapy Clin ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...
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Báo cáo y học: " Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation" pdf
... the development of lung ischemia- reperfusion injury J Thorac Cardiovasc Surg 2003, 126:200-207 Day YJ, Huang L, Ye H, Linden J, Okusa MD: Renal ischemia- reperfusion injury and adenosine 2A receptor-mediated ... and drafted the manuscript JL and ILK helped with the analysis and interpretation of the data VEL helped in conception and design of the experiments, analysis and interpretation of the data and ... dysfunction from pulmonary ischemia- reperfusion injury Ann Thorac Surg 2005, 79:1189-1195 Rivo J, Zeira E, Galun E, Einav S, Linden J, Matot I: Attenuation of reperfusion lung injury and apoptosis by A2A...
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Báo cáo y học: "Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts" pps
... gangeticum orally for 30 days and then sacrificing them for reperfusion- induced ischemic injury Lipid peroxidation in drug treated rat hearts were reduced as compared to ischemia reperfusion control hearts ... enzymes from the assault of ischemia reperfusion injury (Table 4) Conclusion The ethyl acetate extract of Desmodium gangeticum root protects the myocardium against ischemia- reperfusioninduced damage ... the data and prepared the manuscript SS and AR performed the experiment and revised the manuscript JP designed the study, interpreted the data and revised the manuscript All authors read and approved...
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Báo cáo y học: "Effect of Hyperbaric Oxygen Therapy on whole blood cyanide concentrations in carbon monoxide intoxicated patients from fire accident" docx
... oxygen on cyanide intoxication IV Hyperbaric oxygen Toxicol Appl Pharmacol 1972, 22:415-421 19 Gill AL, Bell CN: Hyperbaric oxygen: its uses, mechanisms of action and outcomes QJM 2004, 97:385-395 ... tests by the hyperbaric doctors on duty at the Centre of Hyperbaric Medicine, Rigshospitalet and laboratory staff from the Department of Clinical Biochemistry, nurses in the Trauma Center and nurses ... options including hyperbaric oxygen therapy J Toxicol Clin Toxicol 1989, 27:141-156 18 Way JL, End E, Sheehy MH, De MP, Feitknecht UF, Bachand R, Gibbon SL, Burrows GE: Effect of oxygen on cyanide...
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Role of cyclic AMP signalling mechanisms in heart protection against ischemia reperfusion injury
... Coronary Artery Occlusion and Heart Attack Heart Attack Myocardium Atheroslcerosis Reperfusion Thrombosis Risk Zone IschaemiaReperfusion INJURY Experimental Protocol C IP TP SHP ... cyclic AMP analogue 8Br-cAMP-AM which activates both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of ... ROS PKC Acknowledgements Doctor Andrew James Doctor Mark Bond Professor Saadeh Suleiman Professor Andrew P Halestrap Labs of Professor Saadeh Suleiman and Professor Andrew Halestrap ...
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