investigation of age specific behavioral and proteomic changes in an animal model of chronic ethanol exposure
Báo cáo sinh học: " Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model Linda Petrone1, Maria G Ammendolia2, Armando" ppt
Ngày tải lên :
18/06/2014, 19:20
... developed and tested in animal models Most of the vaccines induced E7 -specific CTLs and were effective in HPV16-related tumour regression in animal models Nevertheless, only few have reached the clinical ... to thank Professor T.C Wu for kindly providing the TC-1 cell line, Dr Jill Marturano for reading and discussing this manuscript, Mr Andrea Giacomelli and Mrs Monica Gabrielli of the MIPI -animal ... al.: Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model Journal of Translational Medicine 2011...
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báo cáo hóa học:" Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model" doc
Ngày tải lên :
20/06/2014, 03:20
... developed and tested in animal models Most of the vaccines induced E7 -specific CTLs and were effective in HPV16-related tumour regression in animal models Nevertheless, only few have reached the clinical ... to thank Professor T.C Wu for kindly providing the TC-1 cell line, Dr Jill Marturano for reading and discussing this manuscript, Mr Andrea Giacomelli and Mrs Monica Gabrielli of the MIPI -animal ... al.: Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model Journal of Translational Medicine 2011...
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Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx
Ngày tải lên :
09/08/2014, 06:23
... adhesion and responses to growth factors and cytokines [2,3] The SLRPs all bind to fibrillar type I and/ or II collagens [4-6] and, in the case of decorin, to fibromodulin and lumican; these interactions ... (rabbit and canine) were of a much younger age than ours Studies using aged human cartilage report much lower average yields, ranging from 0.669 to 0.839 µg/100 mg of OA and 'normal' cartilage [36] ... recovered and mixed by inversion with an equal volume of 70% ethanol, and then loaded onto spin columns Following several washing steps and an on-column DNase digestion (Qiagen, Hilden, Germany),...
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Báo cáo y học: "Pulmonary vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis" ppsx
Ngày tải lên :
13/08/2014, 15:21
... experiments, and analysed and interpreted the data KB contributed in the performance, analysis and interpretation of immunoblotting assays DLT contributed with grant support, study design and interpretation ... synthases (iNOS) and endothelial nitric oxide synthases (eNOS), 3-nitrotyrosine (3-NT) protein and PAR expressions were measured using Western blot and quantified using NIH IMAGE J scanning densitometry ... performed using analysis of variance and bonferroni post hoc test or unpaired t-test Results are presented as mean ± standard error of the mean and a p < 0.05 was considered statistically significant...
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Báo cáo y học: "Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathwa" ppt
Ngày tải lên :
13/08/2014, 20:21
... attenuates VILI and renal hypoperfusion and dysfunction, by maintaining endothelium-dependent vasodilation and decreasing inflammation and tissue injury Materials and methods Animal preparation ... attenuates VILI and renal hypoperfusion and dysfunction, by maintaining endotheliumdependent vasodilation and decreasing inflammation and tissue injury, in the rat kidney during LPS-induced lung injury ... is shown in Figure Animals were treated according to national guidelines and with permission of the Institutional Animal Care and Use Committee (Amsterdam, The Netherlands) A total of 31 male...
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Báo cáo y học: "The laminin b1-competing peptide YIGSR induces a hypercontractile, hypoproliferative airway smooth muscle phenotype in an animal model of allergic asthma" potx
Ngày tải lên :
12/08/2014, 13:22
... contains the RGD-binding motif present in ECM proteins like fibronectin, collagens and laminins [24,25] The specific role of laminins in ASM remodelling in vivo, however, remains to be determined ... fibrosis in YIGSRtreated animals could also indirectly result from increased eosinophilia As increased and altered deposition of ECM proteins, including laminins and collagens, is a feature of remodelling ... Therefore, using a guinea pig model of chronic asthma, we explored the role of laminins in ASM remodelling in vivo, by treating the animals with the specific soluble laminin-competing peptide...
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Báo cáo y học: " Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury" doc
Ngày tải lên :
12/08/2014, 16:20
... controlled environment and provided with standard rodent chow and water Animal care was in compliance with Italian regulations on protection of animals used for experimental and other scientific ... accumulation of water in lung as an indicator of lung edema, (Fig 1f) and neutrophils infiltration in the lung tissues in WT-animals The leukotrienes synthesis inhibition and the receptor blockade in bleomycin ... bleomycin injection in WT mice, positive staining for IL-1 (A) was localized mainly in inflammatory cells and in vascular endothelium There was a marked reduction in the IL-1 immunostaining in the...
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Báo cáo y học: "Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain" doc
Ngày tải lên :
12/08/2014, 17:22
... shows that longterm antinociceptive effects of HA preparations can be assessed in an animal model of joint pain based on the repeated intra-articular injection of bradykinin and PGE2 Boettger ... applicable and significant change in pain-related behavior as assessed employing different methods (see effects of saline and morphine injections) Although in principle, such models, mainly using bradykinin ... treatment of OA Here we report on the magnitude and long-term duration of antinociceptive effects of NASHA and other HA preparations in the bradykinin/PGE model of repetitive joint pain Materials and...
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Báo cáo y học: "Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis" pps
Ngày tải lên :
12/08/2014, 18:20
... inflammation and sepsis References American College of Chest Physicians — Society of Critical Care Consensus Conference: Definitions of sepsis and organ failure and guidelines for the use of innovative ... endotoxin injection in normal subjects J Clin Endocrinol Metab 1994, 79:1605-1608 35 Becker KL, Whang KT, Snider RH, et al: Relation between cytokines and procalcitonin peptides in an animal model of ... dose of E coli (n = 13–15) and killed at 3, 6, 12 and 24 h increased from a baseline of 21 ± pg/ml (mean ± SEM) to 78 ± 3, 542 ± 100, 3570 ± 920, and 4240 ± 1080 pg/ml, respectively The changes in...
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Báo cáo y học: "Hepatic oxidative stress in an animal model of sleep apnoea: effects of different duration of exposure" potx
Ngày tải lên :
13/08/2014, 13:20
... ischemia-reperfusion [18] in which there is activation of xanthine oxidase, leading to the formation free radicals and further imbalance between oxidants and antioxidants [4-6] The analysis of liver integrity ... significant increase in NO in these animals compared with SIH (Table 4) Several histological liver changes were also observed in animals of the IH-35 group - ballooning, steatosis, necrosis and the ... equivalent to an apnea index of 60 per hour The SIH group was housed in an adjacent cage and underwent the same fan activity as the IH group, but no Page of gas was introduced in the cage during the...
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Báo cáo sinh học: " Fuzzy classification of phantom parent groups in an animal model" pptx
Ngày tải lên :
14/08/2014, 13:21
... Genetic model The infinitesimal model assumes that an animal' s breeding value is the sum of the parent average and a Mendelian sampling deviation that resembles the random process of sampling parental ... 0.5u d + φ i , where ui and Ni are the additive genetic value and Mendelian sampling deviation for animal i, respectively, and s and d are the sire and dam of animal i In matrix representation: ... 1), the contributions for animals A-D to elements of A* are in Table For animals A, D and F there are contributions to A*, for animal B and C 16, and for animal E 25 For animal C there are 16 contributions,...
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The tax deferred saving plan and private savings in an OG model with production
Ngày tải lên :
13/10/2015, 15:55
... private income and saving represent the aggregate income and savings in the model Therefore, the saving rate used here is defined as the ratio of total private savings to wage income The main results ... saving rate ሺK remaining variables increase in α as a result of increasing interest rate and wage income ഥ) increases The interest rate is For the case with RRSPs, the total saving ሺK constant ... saving ሺK ഥ /W ഥ ሻ decreases With smaller income ഥ ሻ and saving rate ሺK a result, income ሺW and saving, both cത୷ and cത୭ decrease, and interest factor ሺ1 rҧ ሻ increase yതଵ ഥଵ are decreasing since...
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Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan
Ngày tải lên :
05/09/2013, 10:17
... parts of the grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and the sampling ... condition, and the temperature was maintained constant between 10°C and 30°C RESULTS AND DISCUSSION Materials runoff characteristics and variation in the reservoir Fig indicates time courses of nitrate ... Watanabe M and Tsuno H (2010) Runoff characteristics of nutrients and elements from citrus fruit grove and effects on the behavior, Annual Journal of Hydraulic Engineering, JSCE 54, 1369-1374 (in...
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Báo cáo khoa học: Functional analysis of two divalent metal-dependent regulatory genes dmdR1 and dmdR2 in Streptomyces coelicolor and proteome changes in deletion mutants ppt
Ngày tải lên :
16/03/2014, 18:20
... DNA-binding protein of the ferritin family sco0596 P2 Medium increase Phosphatidylethanolaminebinding protein sco4018 Name P1 Large increase Proteins GenBank accession no Table Protein changes in ... inserted in the XhoI site of dmdR2 (Fig 5) A transformant was first obtained that was resistant to both kanamycin and thiostrepton, indicating that a single recombination, resulting in chromosomal integration ... alignment of domains (DNA–protein interaction), (dimerization and metal binding) and (containing a nonconserved amino acid stretch), of the Streptomyces coelicolor DmdR1 and DmdR2 proteins, with...
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Báo cáo hóa học: " Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice" doc
Ngày tải lên :
18/06/2014, 16:20
... cells in 50 μl of PBS were mixed with 50 μl of matrigel and injected subcutaneously (SC) in the right hind flank of animals Intratumor injections (IT) were given with a × 108 pfu dose of adenovirus ... by TB, AD and JG Flow cytometry analysis was performed by TB, CRG and aided in analysis and production of figures by RH TB, CRG and ES conceived and designed experiments The Canadian collaborators ... TM, Slawin KM: Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin and its soluble receptor with prostate cancer progression Clin Cancer Res...
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báo cáo hóa học: " Indoors illumination and seasonal changes in mood and behavior are associated with the health-related quality of life" pdf
Ngày tải lên :
18/06/2014, 19:20
... September 2000 and July 2001 The two-stage stratified cluster sampling design was planned by Statistics Finland The sampling frame comprised adults aged 30 years and over living in mainland Finland This ... intensity of depressive symptoms only and greater than that of age for instance Of the seasonal changes in mood and behavior, those in energy level, mood and social activity were of significance ... community-dwelling older adults and those living in long-term care settings Conclusion The self-report of seasonal changes in mood and behavior and of poor illumination indoors seem to be relevant indicators...
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Global Firms and Emerging Markets in an Age of Anxiety ppt
Ngày tải lên :
28/06/2014, 00:20
... Global Firms and Emerging Markets in an Age of Anxiety Global Firms and Emerging Markets in an Age of Anxiety Edited by S Benjamin Prasad and Pervez N Ghauri Library of Congress Cataloging -in- Publication ... Control: An Integrated Framework Yan Zhang and Haiyang Li 147 An Analysis of Joint Venture Activities in Southeast Asia Daniel C Indro and Malika Richards 171 National Culture in China and Multinationals’ ... Korea and Taiwan, and the less successful industrialization experiences of Argentina, Brazil, and Mexico 6 Global Firms and Emerging Markets in an Age of Anxiety In chapter 5, Lawton and McGuire...
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Global Firms and Emerging Markets in an Age of Anxiety pptx
Ngày tải lên :
28/06/2014, 22:20
... Global Firms and Emerging Markets in an Age of Anxiety Global Firms and Emerging Markets in an Age of Anxiety Edited by S Benjamin Prasad and Pervez N Ghauri Library of Congress Cataloging -in- Publication ... Control: An Integrated Framework Yan Zhang and Haiyang Li 147 An Analysis of Joint Venture Activities in Southeast Asia Daniel C Indro and Malika Richards 171 National Culture in China and Multinationals’ ... Korea and Taiwan, and the less successful industrialization experiences of Argentina, Brazil, and Mexico 6 Global Firms and Emerging Markets in an Age of Anxiety In chapter 5, Lawton and McGuire...
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Báo cáo lâm nghiệp: "Effect of single Quercus ilex trees upon spatial and seasonal changes in soil water content in dehesas of central western Spain" potx
Ngày tải lên :
07/08/2014, 16:21
... 4.2), taking into account the percentage of gravels Finally, predawn and midday water potentials were measured in Q ilex trees during the summer of 2002 and 2003 by means of the Scholander pressure ... small, can also explain the favourable water status of the trees studied For instance, integrating θ variation in BA site in the first m depth and at 13.3 m of distance – the half of mean distance ... is explained as a consequence of a decrease water input, and an increase of water output in the sub-canopy area The evergreen Q ilex presents a rainfall interception of about 30% [26] and absorbs...
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Báo cáo lâm nghiệp:"Growth and biomass partitioning of Fagus sylvatica L. and Quercus robur L. seedlings in response to shading and small changes in the R/FR-ratio of radiation" pot
Ngày tải lên :
08/08/2014, 01:21
... branches of young Quercus petraea and an increasing length growth of these branches with increasing Response of beech and oak to shading 167 Figure Growth components measured on seedlings of oak and ... branch biomass with increasing light intensity was found by Cornelissen [12] for Castanopsis fargesii and by Wiebel et al [53] for Garcinia mangostana In addition, an increasing number of branches ... °C) dry mass of main stem, branches, leaves and roots were measured for each plant In addition the dry mass of every branch of a quarter of all plants was recorded In order to obtain information...
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