intrinsic properties of polycations dna condensation complex uptake and endosomal release
Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc
Ngày tải lên :
18/02/2014, 11:20
... N P Kaimachnikov and B N Kholodenko parameters and, for clarity of exposition, we present the analysis of the Src cycle in terms of Eqns (6–8) Intrinsic regulatory properties of the Src (de)activation ... synthesis and degradation, in slow oscillations of FAK activity [27] The present study shows that extremely complex dynamic behaviors can be brought about by the intrinsic properties of the minimal ... Figure 4B helps us understand this excitable behavior by presenting the pulse of Src activity in the plane of the inactive and active fractions, si and s1 If the duration of the stimulus exceeds...
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Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot
Ngày tải lên :
14/03/2014, 23:20
... also reported random binding of NAD+ and Man-ol1P [29] It is reasonable to assume that random binding of reactants by AfM1PDH and AfM2DH occurs in rapid equilibrium, and the absence of curvature ... C) about one order of magnitude below the sH of AfM1PDH also randomness in the binding of substrate and coenzyme in each direction of the reaction catalyzed by AfM2DH By way of comparison, an ... force for reduction of Fru6P and oxidation of Table Inhibition of AfM1PDH and AfM2DH by adenine nucleotides at pH 7.1 and 25 C KiEI is a constant describing competitive inhibition of AMP, ADP or ATP...
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Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
Ngày tải lên :
29/03/2014, 00:20
... protein sequence with that of other species (Xenopus, Drosophila, mouse isoforms 1, 2, and 4, rat isoforms and 2, bovine isoforms 1, 2, 3, and 4, and human isoforms 1, 2, 3, and 4) is shown in Fig ... well-characterized, inhibitors of ANT have also been reported [37] Mindful of (a) the well-established ligand profile of ANT, (b) the modulatory role of ANT in the mammalian PTP, and (c) the absence of a Ca2+-induced ... uptake capacity [4,38,39] In order to investigate whether this also applies to Artemia mitochondria, we tested the effect of ADP and ATP in the presence and absence of the ANT inhibitory ligand...
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Báo cáo sinh học: "Research Article A Note on Symmetric Properties of the Twisted q-Bernoulli Polynomials and the Twisted Generalized q-Bernoulli Polynomials" docx
Ngày tải lên :
21/06/2014, 16:20
... generalized q-Bernoulli polynomials attached to χ of higher order and investigate some symmetric properties of them Furthermore, using these symmetric properties of them, we can obtain some relationships ... symmetric properties of the q-Bernoulli polynomials By using the symmetric properties of p-adic integral on X, we can easily derive many interesting symmetric properties related to Bernoulli numbers and ... Park, and Y.-S Ro, “A note on Euler number and polynomials,” Journal of Inequalities and Applications, vol 2006, Article ID 34602, pages, 2006 L.-C Jang and T Kim, “On the distribution of the...
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Báo cáo hóa học: " Research Article Spatial-Temporal Correlation Properties of the 3GPP Spatial Channel Model and the Kronecker MIMO Channel Model" pdf
Ngày tải lên :
22/06/2014, 22:20
... Constant Random Random Constant Constant Random θMS , δn,AoD , δn,AoD , Δn,m,AoD , and Δn,m,AoA as either constants or random variables at three levels To understand better the relationship of the ... value of the cluster-level spatial CCF of the KBSM ρsBS2 and ρsBS2 1s 1s MS MS ρu1 u2 and ρu1 u2 s1 u1 u ρs2 u2 and ρss21u21 Figure 2: The absolute values of the cluster-level spatial CCFs of the ... δn,AoD and δn,AoA are random variables Note that link-level properties are obtained by taking the average of the corresponding cluster-level characteristics over all the realizations of δn,AoD and...
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Báo cáo y học: "Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia" pdf
Ngày tải lên :
14/08/2014, 08:20
... the suggestion of a different origin of wild boars in Japanese islands and Ryukyu islands [45] In the phylogenetic tree of complete mtDNA sequences, all East Asian domestic pig mtDNAs were clustered ... on mainland Japan [50] Evidence of the origin of Japanese domestic pigs was mainly estimated from cultural records and ancient DNA studies Recent studies of ancient DNA conducted in pig and wild ... fragments of the mtDNA D-loop region in 567 domestic pigs and 155 wild boars across China, South East Asia, and India Then, we selected 24 wild boars and domestic pigs and analyzed their entire mtDNA...
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THE INFLUENCE OF THE KU80 CARBOXY-TERMINUS ON ACTIVATION OF THE DNA-DEPENDENT PROTEIN KINASE AND DNA REPAIR IS DEPENDENT ON THE STRUCTURE OF DNA COFACTORS Derek S.
Ngày tải lên :
24/08/2014, 09:33
... region of Ku80 and DNA- dependent protein kinase catalytic subunit (DNA- PKcs) Discrimination of terminal DNA sequences, on the other hand, occurs independently of Ku 80 C-terminal interactions and ... 42.4ng of DNA- PK, 500 µM p53 synthetic peptide and varying amounts of DNA Reactions with 30bp and 60bp substrates were performed with 500fmol of DNA per reaction to a final concentration of 25nM ... kinase-like protein kinases FAT FRAP, ATM, and TRRAP C-terminus Carboxy terminus dsDNA double-strand DNA ssDNA single-strand DNA SAP SAF-A/B, Acinus, and PIAS domain VHS Vps27p/Hrs/STAM XLF XRCC4-like...
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Glass formation and magnetic properties of ternary fe b y nd and quaternary fe b nd nb alloys
Ngày tải lên :
12/09/2015, 08:18
... FORMATION AND MAGNETIC PROPERTIES OF TERNARY FE-B-Y/ND AND QUATERNARY FE-B-ND-NB ALLOYS ZHANG JIE (M.Sc., Chongqing Univ.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF PHYSICS ... Summary of Tm and Tl of Fe-B-Y alloys studied 50 Table 3.2 Thermal properties for as-spun ribbon samples of alloys Fe95.7-yByY4.3 (y=15 to 35) 55 Table 3.3 Thermal properties of ... cost of iron, exceptionally high strength and superior magnetic properties, which may benefit the research and applications of metallic glasses Glass forming ability (GFA), magnetic properties and...
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Báo cáo khoa học: Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria doc
Ngày tải lên :
07/03/2014, 00:20
... chain supercomplexes, liberating monomeric (holo-) complex IV and a complex III2 ⁄ complex IV supercomplex [18] The migration of complex IV, dimeric complex III, complex I and their supercomplexes ... the core I subunit of complex III (a -complex III) and the COI subunit of complex IV (a -complex IV) The asterisk indicates a complex of approximately 250 kDa complex forms of complex IV, mitochondria ... supercomplex forms [18] The relative positions of supercomplexes comprising complex I, complex III and complex IV (CI ⁄ CIII2 ⁄ CIV), complex III and complex IV (CIII2 ⁄ CIV), as well as dimeric complex...
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Báo cáo khoa học: Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation pdf
Ngày tải lên :
16/03/2014, 10:20
... in DNA binding for the loop connecting strands b2 and b3 in HPV-16, and for the regions close to strands b1 and b4 in BPV-1 For HPV-16, the flexibility of the loop may alter the adaptability of ... in the DNA recognition kinetics and in the stability of the complex [22], suggesting that there is an involvement of this loop in HPV-16 E2 DNA recognition Another interesting aspect of HPV-16 ... the presence of Lys349 in the loop connecting helix a2 and strand b4 This residue may have a role in DNA binding, as a single mutation of Lys349 to alanine weakens the DNA binding of the HPV-16...
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Đề tài " Extension properties of meromorphic mappings with values in non-K¨ahler complex manifolds " pot
Ngày tải lên :
22/03/2014, 16:20
... Sections 2.3 and 2.4 of [Iv-4] while reading proofs of both Lemma 1.3 and Main Theorem I would like to give my thanks to the referee, who pointed out to me a gap in the proof of the analyticity of the ... sequence of analytic subsets (always of pure dimension k) and nj are positive integers called multiplicities of Zj Let |Z| := j Zj be EXTENSION PROPERTIES OF MEROMORPHIC MAPPINGS 801 the support of ... and the support |Z| of Z is connected We put Cf := C>0 Cf,C and shall show that Cf is an analytic space of finite dimension in a neighborhood of each of its points Let Z be an analytic cycle of...
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Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
Ngày tải lên :
23/03/2014, 17:22
... points) at 25 C, 30 C and 35 C in order to identify scalar and dipolar connectivities among heme and amino acid residues Spectral widths of 13 kHz and mixing times of 80 ms for NOESY and 50 ms for TOCSY ... the remainder of the target residues assigned by detection of NOESY residueheme and interresidue cross-peaks solely by the standard Mb fold, and the observation of relaxation effects and/ or sufcient ... Tyr66(E7) (G) and Leu70(E11) (E), and to NHs of heme-residue contacts Tyr66(E7) and Phe46(CD1) to have propionates (A, B, C) and interresidue contacts from Tyr66(E7) to Phe46(CD1) and NHs of Arg48(CD3)...
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Báo cáo khoa học: Expression and characterization of cyanobacterium heme oxygenase, a key enzyme in the phycobilin synthesis Properties of the heme complex of recombinant active enzyme potx
Ngày tải lên :
23/03/2014, 20:22
... addition of NADPH Shift of the Soret maximum to 410 nm and appearance of the 534 and 573 nm bands in the visible region indicate that the oxy complex of heme–Syn HO-1 is produced within and accumulated ... [23], and Hem O, N meningitidis A 2855 [25] Soret and Q (a and b) bands of the oxy form and the CO-bound form not show specific differences from those of mammalian or bacterial HOs The small band ... decrease of the Soret and 498 nm bands and the shift of the band at 630 nm to the longer-wavelength direction At the same time, a broad band with the maximum at approximately 690 nm appears and increases...
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Báo cáo Y học: Purification and catalytic properties of a CO-oxidizing:H2-evolving enzyme complex from Carboxydothermus hydrogenoformans doc
Ngày tải lên :
23/03/2014, 21:20
... mass of a complex containing a single copy of each hydrogenase subunit (CooM, K, L, X, U and H) and two copies of each CO dehydrogenase subunit (CooF and CooS) with a calculated molecular mass of ... enzyme complex (Eur J Biochem 269) 5717 Fig Genetic organization of the coo genes encoding the subunits of the CO-oxidizing:H2-evolving enzyme complex of C hydrogenoformans The cooMKLXUHhypA and ... densitometric analysis revealed a molar ratio of CooS to CooH, the catalytic subunit of the hydrogenase, of 2.1 ± 0.1 : and a molar ratio of CooF to CooH of 1.9 ± 0.1 : The same results were obtained...
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Báo cáo khóa học: Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo pot
Ngày tải lên :
30/03/2014, 13:20
... and its kinetics Uptake of the neoglycoproteins into organs other than liver, kidney and spleen was rather low This is in accordance with our previous results and with studies of the uptake of ... Principles for the Care and Use of Laboratory Animals of the Japanese Pharmacological Society and with the approval of Tokyo University of Science’s Institutional Animal Care and Use Committee Results ... GlcNAc as ligands (Eur J Biochem 271) 127 Fig Illustration of major aspects of the conformational ensembles of sialylated derivatives of the biantennary nonasaccharide Bi9 (A) and of the decasaccharide...
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Báo cáo hóa học: " The Role of Intrinsic and Surface States on the Emission Properties of Colloidal CdSe and CdSe/ZnS Quantum Dots Giovanni Morello Æ Marco Anni Æ Pantaleo Davide Cozzoli " potx
Ngày tải lên :
22/06/2014, 18:20
... demonstrated that the PL of CdSe core and CdSe/ZnS core/shell QDs in the first ns arises from the intrinsic bright ± 1U and ± 1L states with lifetime of about 60 ps and 450 ps, respectively, and from surface ... superposition of three lorentzian curves (see inset of Fig 1A), obtaining the energetic separations among the three states, E1,2 and E2,3 We found E1,2 = 21 meV and E2,3 = 16 meV for core QDs and E1,2 ... times from intrinsic bright states of the fine structure of spherical CdSe QDs [4] into the surface defect states [5], and t3 is comparable with typical lifetime of surface-related emission in CdSe...
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Báo cáo y học: "Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export" pps
Ngày tải lên :
13/08/2014, 06:20
... Both LMB treatment of wt Tax and mutation of the NES (TaxM33) prevented the nuclear export of Tax following DNA damage [11] In addition, LMB treatment of wt Tax and mutation of the NES (TaxM33) ... Mutation of lysine residues 280 and 284 prevents UV-induced dissociation of Tax from TSS Mutation of lysine residues 280 and 284 prevents UV-induced dissociation of Tax from TSS Wild-type (A and B), ... the ratio of mono-ubiquitinated (upper Tax band) to total Tax (upper and lower Tax bands) for both unirradiated and UV irradiated cells These results demonstrate that mono-ubiquitination of Tax...
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Báo cáo y học: "All motifs are not created equal: structural properties of transcription factor - dna interactions and the inference of sequence specificity" doc
Ngày tải lên :
14/08/2014, 14:21
... bound to DNA and the information profile of its PWM, is that if we knew (or could predict) the footprint of a transcription factor on DNA then we would expect the information profile of the PWM ... Structural Properties of Transcription Factor – DNA Interactions and the Inference of Sequence Specificity Michael B Eisen Affiliations: Center for Integrative Genomics Division of Genetics and Development ... temporal, positional and conditional pattern of expression of each gene is a function (albeit a very complicated one) of the arrangement of transcription factor binding sites in its cis -DNA Thus, in...
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Electronic, magnetic and optical properties of atomically controlled complex oxide heterostructures and interfaces
Ngày tải lên :
09/09/2015, 10:07
... MAGNETIC AND OPTICAL PROPERTIES OF ATOMICALLY CONTROLLED COMPLEX OXIDE HETEROSTRUCTURES AND INTERFACES XIAO WANG (B.Sc, Shandong University, P.R China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF ... Xie, Dr Jiabo Yi, Tom Wijnands, Wentao Xu, Dr Kalon Gopinadhan, Prof Alexander Brinkman, Asst Prof Wei Chen, Prof Ganaphathy Baskaran, Assoc Prof Jun Ding, Asst Prof Andrivo Rusydi, Joost Beukers, ... materials and structures, exploration of the properties, understanding of the underlying mechanisms and novel designs of possible devices are needed This chapter aims to give an overview of my research...
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