... interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin, galectin-3 [16-18], some of which are also important tools in the diagnosis and pathogenesis of heart failure, in the ... IL-9 and IFN-g plasma levels with the patients echocardiographic parameters, such as LVEF and LVIDd, andwith disease duration Interestingly, in ICM patients, IL-9 levels inversely correlated with ... Cytokine plasma levels increased in ICM and NIDCM CHF patients vs controls Plasma levels of MIP-1 b (A), VEGF (B), MCP-1 (C), IL-9 (D), IL-8 (E), and IL-6 (F) inpatientswithchronicheart failure...
... interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin, galectin-3 [16-18], some of which are also important tools in the diagnosis and pathogenesis of heart failure, in the ... IL-9 and IFN-g plasma levels with the patients echocardiographic parameters, such as LVEF and LVIDd, andwith disease duration Interestingly, in ICM patients, IL-9 levels inversely correlated with ... Cytokine plasma levels increased in ICM and NIDCM CHF patients vs controls Plasma levels of MIP-1 b (A), VEGF (B), MCP-1 (C), IL-9 (D), IL-8 (E), and IL-6 (F) inpatientswithchronicheart failure...
... 10 and 13 The association of an initial high level of IL-6 with organ failureand poor outcome is confirmed inpatientswith sepsis, after trauma and AAA patients [22-25] The initial increase in ... discussion Inpatientswith sepsis, low HLA-DR expression is associated with monocyte deactivation, an anti-inflammatory cytokine profile, infectious complications and death [30,31] Inpatientswith ... during surgery, four patients were not included because of absence of one of the primary investigators (JWH or APvdB), and for one patient no informed consent was obtained Of the remaining 30 patients, ...
... Lavoie J, Guertin MC, Racine N, He Y, Yao G, Rouleau JL, Schiffrin EL, Touyz RM: Increased systemicinflammationand oxidative stress inpatientswith worsening congestive heart failure: improvement ... all patients care continued to be at the discretion of the attending physician, including inotrope administration and dosing It is well recognized that heartfailure leads to increased circulating ... failure, and the effect milrinone in ischemic subset of patients deserves further investigation Conclusion Initiation of milrinone therapy inpatientswith severe heartfailureand reduced cardiac output...
... HADS Patients completed the self-administered and validated German version of the HADS[19] The HADS measures depression and generalised anxiety in in- and outpatients andin community settings ... approximately 1.5 points in COPD patients Investigators and those interpreting clinical research can use this minimal important difference to determine whether treatment effects are in a range that ... determine the minimal important difference of the HADS The CRQ is a widely used instrument in respiratory rehabilitation and measures dyspnea, fatigue, emotional functioning and coping with COPD.[20]...
... province of China Mandarin is spoken Due to the pictorial nature of Chinese writing, both Cantonese and Mandarin-speaking Chinese would be able to read the Chinese version of the HADS In Europe, ... screening and case detection utility and accuracy [16] The present study was designed to examine the underlying factor structure of the Chinese version of the HADS in a mainland Mandarin-speaking ... were males In terms of the clinical data, over two thirds of subjects were angina The finding of high proportions of Chinese CHD patients screening positive with anxiety and depression using the...
... clinical measures in combination in a single model to predict the EQ-5D index In this case, disease severity was taken into account using a single variable, and more implicitly from the point of view ... disease and interventions inpatients ranging from early disease managed medically to end-stage heartfailureand are described briefly in Table Measurements in the different studies were divided into ... angina, where a model mapping clinical measures on to the EQ-5D index explained 37% of the variability in the EQ-5D index and also performed poorly in individuals with EQ-5D index values of about...
... assess the inter-laboratory variability of FibroTest and ActiTest, including their six serum liver components, inpatientswithchronic liver disease, and to identify factors associated with that ... The tests combine five components (α2-macroglobulin, haptoglobin, apolipoprotein A1, γ-glutamyl transpeptidase (GGT), and total bilirubin) for FibroTest and same plus alanine aminotransferase ... 0.37 ± 0.12 1 0 se – standard error over the investigated range As previously observed, when ordinary linear regression (in combination with correlation analysis in the Passing Bablock method) gave...
... biopsy and METAVIR staging and grading performed Of these patients, 453 were from our center [11,14], including 130 patients coinfected with HCV and HIV [14] Eight hundred and seventy (870) patients ... "FibroTest" and "ActiTest" in Medline andin the abstract books of hepatology, gastroenterology, internal medicine and infectious diseases annual meetings Only publications or abstracts concerning FT-AT ... diagnostic value of FibroTest for the staging of hepatic fibrosis and comparisons with hyaluronic acid, the Forns Index and the APRI Index inpatientswithchronic hepatitis C, from the published...
... co-morbidities found in our patients including history of CAD in 38%, history of CHF in 27%, arterial hypertension in 53% and COPD in 39% and the positive effect of betablocker therapy in these different ... displaying one-year mortality with or without treatment with beta-blocker at admission inpatientswith cardiac aetiology of respiratory failure (adjudicated final diagnosis of heart failure; ... mortality in individuals withand without cardiovascular disease [24] Angiotensin converting enzyme inhibitors (ACEi)/ angiotensin receptor blockers (ARB) and beta-blockers build the mainstay of...
... patient actually having an infarction [37] Other investigators found that in predicting return to work inpatientswith coronary disease, both physicians' andpatients' estimates had independent prognostic ... severity and incorporating both perspectives in clinical decision making and outcomes research may be important Competing interests The author(s) declare that they have no competing interests ... participated in acquisition and interpretation of data, and drafting of the manuscript KWW was involved in conceptualizing the study design and acquisition of data WMT and ANB participated in acquisition...
... multidisciplinary clinical activity in the improvement of care for CHF patients, and this has been addressed in this project We now use the multidisciplinary practice guideline as a starting point instead ... assessed using the guideline adherence index (GAI), indicating the proportion of indicated drugs that is prescribed [27,28] These include ACE inhibitors and beta blockers, and – depending on the ... identifying barriers and tailoring intervention to these barriers may improve clinical practice compared to no intervention and to guideline dissemination In their meta analysis including eight studies...
... other extracellular matrix proteins, resulting in thickening of the skin and fibrosis of the affected organs (for example, gastrointestinal tract, lung, heart, and kidney) The etiology of SSc ... analysis accounting for these factors, however, failed to demonstrate a significantly increased use in these patients Azathioprine, originally introduced in transplantation medicine in the 1960s, ... specializing in the care of SSc patients participating in the network, but also of patients who are seen only once a year in a clinical center participating in the network and otherwise receive care...
... conducted by Diaz-Peromingo et al., who also didn’t find any relationship between Lp(a) levels and AF [13] They compared 101 patientswith AF and 101 patientswith sinus rhythm in control group They ... recurrence, inflammationand left atrium diameter inpatients after successful EC of persistent AF Further studies are needed to elucidate the role of Lp(a) in this clinical setting, preferably inpatients ... Lipoprotein(a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis Blood 2001, 98:2980-7 Kim SM, Lee JH, Kim JR, Shin DG, Lee SH, Cho KH: Female patients...
... vasoconstrictor and water-retaining and sodium-retaining systems such as the renin–angiotensin–aldosterone system and the sympathic nervous system, andin the nonosmotic release of arginine vasopressin Persistent ... albumin-bound toxins, typically present in AoCLF • Compared with SMT alone, the MARS and Prometheus devices significantly decrease albumin-bound toxins (bile acids, bilirubin) inpatientswith ... unit these patients are routinely treated with terlipressin and albumin, which might have interfered with the haemodynamic measurements Study design The study was designed to include 18 patients, ...
... vitamins A (retinol), D (cholecalciferol) and E (α-tocopherol) inpatientswith CAD MATERIALS AND METHODS The study population included 30 patients having angiographically demonstrated CAD and ... vitamins (retinol, tocopherol and cholecalciferol), and trace elements and heavy metals (Zn, Cu, Fe, Cd, Pb and Mn) inpatientswith CAD and the control group are shown in Table Compared with the ... increase in urine Cu levels inpatients suffering from myocardial infarction (MI) (15) Reunanen et al (1996) found increased levels of serum Cu inpatientswith CAD (14) In contrast, in our study,...
... survival for patientsin a randomized study failing first line trastuzumab therapy was 25.5 months for patients receiving continuous trastuzumab combined with capecitabine [54] In another randomized ... clinical study with only six patients completing all three cycles of vaccine and cytokine administration, this precludes any conclusion regarding the clinical efficacy Further complicating interpretations ... binding activity of patients evaluable at all time points (patient #3, 4, 8, pre, post and late) C Binding activity in the serum of all patients at all available individual time points (pre- and...
... 100, the lower scores indicating better health status [19-21] The SGRQ has been translated into different languages and used in several studies of COPD patients, including in Norway [22,23] The ... with lower physical health, and better lung function, and greater anxiety and depression were associated with a lower mental health, with symptoms explaining the greatest variance These findings ... life and symptoms in primary care COPD patients Family Practice 2007, 24:217-223 Rejeski JW, Foley KO, Woodard M, Zaccaro DJ, Berry MJ: Evaluating and understanding performance testing in COPD patients...
... greater in weight bearing bones (5.1% at lumbar spine and 2.5% at femoral neck) that non-weight bearing non-dominant distal radius (0.9% in tBMD, 0.2% in iBMD, and 0.1% in cBMD) This finding was ... and Research 2007, 2:9 http://www.josr-online.com/content/2/1/9 Table 2: BMD data at baseline, 6- and 12-months Comparison of BMD at baseline and its changes at 6- and 12-months inpatientswith ... Surgery and Research 2007, 2:9 http://www.josr-online.com/content/2/1/9 Table 3: Bone formation and resorption markers Bone Alkaline Phosphate (BALP) and Deoxypyridinoline (DPD) level inpatients with...
... [10,28,29], in individuals with CVD [30] in individuals with risk factors for CVD [31,32] andin men with diabetes [33] HRR is positively associated with insulin sensitivity as measured with a hyperinsulinemic-euglycemic ... Jorgen FH: Increased heart rate and reduced heart- rate variability are associated with subclinical inflammationin middleaged and elderly subjects with no apparent heart disease Eur Heart J 2004, 25:363-370 ... insulin and glucose levels, HOMA score, T, FAI, andwith an increase in SHBG [49] In addition, HRR was significantly related to the reduction in body weight and waist circumference [49] These findings...