intermezzo a data analysis session
Báo cáo y học: "ProCAT: a data analysis approach for protein microarrays" pot
... three aspects: experimental designs, data file formats and normalization parameters Experimental design contains parameters such as the number of test arrays and negative control arrays for one particular ... one particular assay Data file format describes the layout in the uploaded dataset so that ProCAT can recognize and extract the useful information from it Normalization parameters allow users ... Signal Figure A representative protein microarray with high-quality data A representative protein microarray with high-quality data The slide image was reconstructed from a protein microarray...
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Tài liệu A Comparison of Approaches to Large-Scale Data Analysis pdf
... Muralikrishna GAMMA - A High Performance Data ow Database Machine In VLDB ’86, pages 228–237, 1986 S Fushimi, M Kitsuregawa, and H Tanaka An Overview of The System Software of A Parallel Relational Database ... data) have approximately constant performance for this task, since each node has the same amount of Document data to process and this amount of data remains constant (7GB) as more nodes are added ... that it was a mistake for the database research community in the 1970s to focus on data sub-languages that could be embedded in any programming language, rather than adding high-level data access...
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quantitative data analysis in education - a critical introduction using spss - p. connolly (routledge, 2007) ww
... save a dataset and also the output of the analyses you have undertaken Understanding what a dataset is At the heart of quantitative data analysis is the dataset A dataset is actually just an array ... illiteracy rates (%) Males Argentina Benin Burundi Chile Dominican Republic El Salvador Ghana Hungary Iran Laos Malta Mauritania Morocco Namibia Senegal Sierra Leone Swaziland Macedonia United Arab ... quantitative data; including data derived from large, national and international datasets; the ability to summarize data, not just in relation to the production of appropriate summary statistics...
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john a rice mathematical statistics and data analysis, second edition 1994
... chapter, theoretical results are balanced by more qualitative data analytic procedures based on analysis of residuals Chapter 15 is an introduction to decision theory and the Bayesian approach ... Printed in the United States of America 345 89 10-98 97 96 95 94 Library of Congress Cataloging-in-Publication Data Rice, John A. , Mathematical statistics and data analysis / John A Rice —2nd ed p cm ... sampling Several other data sets were brought to my attention by statisticians at the National Bureau of Standards, where I was fortunate to spend a year while on sabbatical I deeply appreciate...
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báo cáo sinh học:" Health worker densities and immunization coverage in Turkey: a panel data analysis" ppt
... studies, variables on GDP per capita, female adult illiteracy and land area are also included Data on per capita GDP and female adult illiteracy are limited to the year 2000 – the last year that both ... [15] Data on provincial population levels, per capita GDP, land area and female adult illiteracy are published by the Turkish Statistical Institute [16] Dependent variable Data on immunizations are ... future vaccination coverage? The analysis takes advantage of a panel dataset to extend prior research on this subject It offers not only insights into immunization rate variation at any particular...
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báo cáo hóa học: " Internal construct validity of the Warwick-Edinburgh Mental Well-being Scale (WEMWBS): a Rasch analysis using data from the Scottish Health Education Population Survey" potx
... has been argued that both the latter approaches are inappropriate, given that factor analysis is parametric and requires interval scaling, and Cronbach's Alpha does not address unidimensionality ... unidimensionality Educational and Psychological Measurements 1977, 37:827-838 McDonald RP, Ahlawat KS: Difficulty factors in binary data British Journal of Mathematical and Statistical Psychology ... Guttman LA: The basis for Scalogram analysis In Studies in social psychology in World War II: Measurement and Prediction Volume Edited by: Stouffer SA, Guttman LA, Suchman FA, Lazarsfeld PF, Star...
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Báo cáo hóa học: "Research Article Microarchitecture of a MultiCore SoC for Data Analysis of a Lab-on-Chip Microarra" docx
... incorporated on the system MICROARRAY DATA PROCESSING ALGORITHM Statistical analysis of microarray data can essentially process massive amounts of data and can also adjust for various sources of variability ... SYSTEM-ON-CHIP ARCHITECTURE FOR MICROARRAY DATA ANALYSIS We describe and evaluate in detail the two alternative architectures of the single-core and multicore approach Also, the details for the data analysis ... Mukherjee, “Classifying microarray data using support vector machines,” in A Practical Approach to Microarray Data Analysis, D Berrar, W Dubitzky, and M Granzow, Eds., pp 166–185, Kluwer Academic Publishers,...
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Báo cáo hóa học: " Research Article Extraction of Protein Interaction Data: A Comparative Analysis of Methods in Use" potx
... 2.1 Manual curation PathArt (proprietary pathway database from Jubilant Biosys Ltd.) is a manually curated database which covers more than 2800 signaling and metabolic pathways across 34 diseases ... method, and intracellular localization (cytoplasm, membrane, and nucleus) Data is manually entered into PathArt using a curator work bench, a software tool that accepts data in a defined format, and ... abstract Results were copied into an Excel file for analysis Data analysis Results obtained from PreBIND and RLIMS-P where cross verified with data from IMaps The IMaps data was comparatively analyzed...
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Báo cáo hóa học: " DNA Microarray Data Analysis: A Novel Biclustering Algorithm Approach" potx
... mathematical modeling and analysis of biological systems and data (genomics, proteomics, DNA microarray, gene expression, gene regulatory networks, and computational biology.) He did work as an ... biclustering algorithm that can be used to extract from a set of data biclusters with constant values, constant values on rows, constant values on columns, and coherent values We also described an approach ... in A, and L is the number of distinct values in A Algorithm 1, which is used for data quantization, requires about (N × M × L) operations One has to note that this step is optional After data...
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Báo cáo y học: "A human functional protein interaction network and its application to cancer data analysis" potx
... non-Reactome human-curated pathway databases were imported into the Reactome database (28 March 2009 release) These four databases are: Panther [27], CellMap [61], NCI Pathway Interaction Database ... high-coverage, unreliable pairwise data sets with low-coverage, highly reliable pathways to create a pathway-informed data analysis system for high-throughput data analysis As the first step towards achieving ... pathway-based data analysis system for high-throughput data analysis We have applied this system to the analysis of two genome-wide GBM data sets and data sets from other cancer types and revealed...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 2 pptx
... of acids and bases: a L ewis acid is any substance that can act as an electron pair acceptor, and a L ewis base is any substance that can act as an electron pair donor In many enzymatic reactions, ... Brønsted—Lowry classification, an acid is any substance that can donate a proton, and a base is any substance that can accept a proton by reacting with a Brønsted—Lowry acid After donating its proton, a Brønsted—Lowry ... example, that the product of an unfavorable reaction was also a reactant for a thermodynamically favorable reaction As long as the absolute value of G was greater for the second reaction, the overall...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 3 pot
... nonequivalent ligand binding sites The data and fit to Equation 4.27 are the same as for Figure 4.5 in all fields put a great deal of emphasis on finding mathematical transformations of data that would ... binding and washing steps are greatly facilitated by use of vacuum manifolds of various types that are now commercially available (Figure 4.1 5A) With this apparatus, the membrane sits above a vacuum ... have equal concentrations of ligand at the initiation of the experiment) The chambers are then sealed, and the apparatus is place on an orbital rocker, or a mechanical rotator, in a thermostated...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 4 ppsx
... initial experiments with a limited number of data points that span as broad a range of substrate concentrations as possible (at least a 100-fold substrate concentration range) to obtain a rough ... noncovalently associated as a multiprotein complex This supercomplex, referred to as CAD, comprises the enzymes carbamyl phosphate synthase, aspartate transcarbamylase, and dihydroorotase Because the active ... ENZYME REACTIONS data points within this range Table 5.1 illustrates an ideal situation for determining V and K The data span a 250-fold range of substrate concentrations that cover the range...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 5 docx
... TRANSITION STATE STABILIZATION 165 Table 6.2 Some examples of electrophilic catalysis in enzymatic reactions Enzyme Acetoacetate decarboxylase Aldolase Aspartate aminotransferase Carbonic anhydrase ... by acting as Brønsted—Lowry acids and bases in what is referred to as general acid and general base catalysis For catalysis by small molecules (nonenzymatic reactions), general acid/ base catalysis ... of reaction for (A) a general base-catalyzed reaction and (B) a general acid-catalyzed reaction itself Identification of the group(s) participating in general acid/base catalysis in enzymes has...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 6 pot
... noise and having a reasonable signal to Figure 7.10 Deviation from Beer’s law Over a small concentration range, the absorption at some analytical wavelength tracks linearly with analyte concentration, ... recommended names, alternative names, catalytic activities, information on cofactor utilization, and associated diseases for a very large collection of enzymes A complete description of the data bank and ... spectroscopy as an analytical tool is that the absorption of a molecule at a particular wavelength can be related to the concentration of that molecule in solution, as described by Beer’s law: A : cl...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 7 pdf
... formation by HPLC, one typically measures the integrated area under a peak in the chromatograph and compares it to a calibration curve of the area under the peak as a function of mass for a standard ... commonly used alternative methods are available to quantify peaks from strip-chart recordings The first is to measure the peak height rather than integrated area as a measure of analyte mass This is ... the antibody Secondary antibodies bearing a variety of labels can be purchased A popular strategy is to use a secondary antibody that has been covalently labeled with biotin, a ligand that binds...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 8 docx
... quantitative structure—activity relationships (QSAR) was first championed by Hansch and his coworkers (Hansch, 1969; Hansch and Leo, 1979) In a typical QSAR study, a series of analogues of a lead ... 2,4-diaminopyrimidines (B) as inhibitors of the dihydrofolate reductase from L casei [Data from Coats et al (1984).] vibrational frequencies for the reactant and transition state species that accompany heavy isotope ... of an inhibitor as an IC value Despite their convenience and popularity, IC value measurements can be misleading if used inappropriately The IC value of a particular inhibitor can change...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 9 ppt
... would invalidate the subsequent data analysis Thus it may be necessary to evaluate several combinations of enzyme, substrate, and inhibitor concentrations to find an appropriate range of each for ... formation of a tetrahedral transition state involving a peptide carbonyl carbon of the substrate and an active site serine residue as the attacking nucleophile Several groups have taken advantage ... 2695 Cha, S., Agarwal, R P., and Parks, R E., Jr (1975) Biochem Pharmacol 24, 2187 Copeland, R A (1994) Methods of Protein Analysis, A Practical Guide to L aboratory Protocols, Chapman & Hall,...
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A Practical Introduction to Structure, Mechanism, and Data Analysis - Part 10 doc
... W Perrella, Anal Biochem 174, 437 (1988) Graphfit A commercial package for data management and graphic display of enzyme kinetic data and other scientific data graphing This program has extensive ... type and relevant kinetic constants, as well as statistical analyses of one’s data Reference: W W Cleland, Methods Enzymol 63, 103 (1979) Enzfitter A commercial package for data management and graphic ... Corporation Web site [http://www.kintek-corp.com] MPA A program for analyzing enzyme rate data obtained from a microplate reader Provides a convenient means of transforming and analyzing data directly...
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