inhalation and aspiration syndromes
Báo cáo y học: "Re-inspiration of CO2 from ventilator circuit: effects of circuit flushing and aspiration of dead space up to high respiratory rate" pot
... inspiratory line, Figure Aspiration and/ or Circuit Flushing were performed over the last 30% of expiration time Flow rate and volume for Aspiration and Circuit Flushing were adjustable Aspiration volume ... at different RR and VT has not been studied The objective of this study was to quantify re-inspiration from the Y-piece and adjacent parts of tubing at ordinary and increased RR and to examine ... rate, being 0.22 L·sec-1 at RR20 and 40, was increased to about 0.35 L·sec-1 at RR60 to assure that flushing and aspiration volumes were not less than 60 ml and sufficient to clear the tracheal...
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Báo cáo y học: "Inhalation with Fucose and Galactose for Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients"
... arms in a ratio of 1:2 (inhalation: inhalation + antibiotics) This ensured that most of the patients were treated with antibiotics and that an effect of inhalation alone and inhalation with antibiotics ... or FEV1 with inhalation alone or combined therapy (P > 0.05; data not shown) Int J Med Sci 2008, 374 Fucose/galactose inhalation decreases TNFα expression Both inhalation alone and combined ... or combined treatment with inhalation and i v antibiotics (p i + i v.) Mean+SEM *: P < 0.05 vs pre Fucose/galactose inhalation does not affect inflammatory markers and liver function No significant...
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Báo cáo hóa học: " Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" docx
... CP and JR designed the study and were responsible for the idea of the study CP, RG, SH and JI participated in patient enrrollment and manuscript elaboration DB wrotte the manuscript in part and ... sociodemographic and clinical data required for patient characterization and was required to classify patients into two broad diagnostic categories corresponding to NP and NNP, and to further subcategorize ... 15.3 years (± standard deviation)] to assess initial feasibility and potential understanding problems The final version was Page of 10 (page number not for citation purposes) Health and Quality of...
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báo cáo hóa học:" Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" pdf
... CP and JR designed the study and were responsible for the idea of the study CP, RG, SH and JI participated in patient enrrollment and manuscript elaboration DB wrotte the manuscript in part and ... sociodemographic and clinical data required for patient characterization and was required to classify patients into two broad diagnostic categories corresponding to NP and NNP, and to further subcategorize ... 15.3 years (± standard deviation)] to assess initial feasibility and potential understanding problems The final version was Page of 10 (page number not for citation purposes) Health and Quality of...
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Syndromes and a Century – Cấu trúc của sự tương phản docx
... qua kỹ thuật xây dựng hình ảnh thông qua lời kể nhân vật Và Syndromes and a Century Apichatpong tác phẩm Có thể thấy, nhân vật Syndromes and a Century kiệm lời có nói kể câu chuyện hài hước nói ... phim Syndromes and a Century nghệ thuật lấy cảnh quay Cách lấy cảnh quay dàn dựng khéo léo nêu bật chủ đề phim, thể tư tưởng người làm phim Cảnh quay tinh tế hấp dẫn người xem nhiêu Trong Syndromes ... cho người xem thấy thông điệp: vị trí thiên nhiên người hoán đổi cho từ đây.Âm thanhÂm phim Syndromes and a Century Apichatpong chăm chút kỹ lưỡng Âm sử dụng chủ yếu âm khuôn hình để làm bật hình...
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Syndromes and a Century – Cấu trúc của sự tương phản potx
... qua kỹ thuật xây dựng hình ảnh thông qua lời kể nhân vật Và Syndromes and a Century Apichatpong tác phẩm Có thể thấy, nhân vật Syndromes and a Century kiệm lời có nói kể câu chuyện hài hước nói ... phim Syndromes and a Century nghệ thuật lấy cảnh quay Cách lấy cảnh quay dàn dựng khéo léo nêu bật chủ đề phim, thể tư tưởng người làm phim Cảnh quay tinh tế hấp dẫn người xem nhiêu Trong Syndromes ... cho người xem thấy thông điệp: vị trí thiên nhiên người hoán đổi cho từ đây.Âm thanhÂm phim Syndromes and a Century Apichatpong chăm chút kỹ lưỡng Âm sử dụng chủ yếu âm khuôn hình để làm bật hình...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 1) ppsx
... (idiopathic thrombocytopenic purpura or due to splenomegaly), and granulocytes (as in the immune leukopenias) Hematopoietic failure syndromes are classified by dominant morphologic features of ... marrow (Table 102-1) While practical distinction among these syndromes usually is clear, they can occur secondary to other diseases, and some processes are so closely related that the diagnosis ... one diagnosis may appear to evolve into another Many of these syndromes share an immune-mediated mechanism of marrow destruction and some element of genomic instability resulting in a higher...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 2) ppsx
... hemoglobinuria (PNH; Chap 101) and to MDS, and in some cases a clear distinction among these disorders may not be possible Epidemiology The incidence of acquired aplastic anemia in Europe and Israel is two ... Israel is two cases per million persons annually In Thailand and China, rates of five to seven per million have been established In general, men and women are affected with equal frequency, but the ... with equal frequency, but the age distribution is biphasic, with the major peak in the teens and twenties and a second rise in the elderly Etiology The origins of aplastic anemia have been inferred...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 3) pdf
... marrow failure Vast quantities of epidemiologic, clinical, and laboratory data link benzene to aplastic anemia, acute leukemia, and blood and marrow abnormalities The occurrence of leukemia is roughly ... translates, in a rare disease, to but a handful of drug-induced aplastic anemia cases among hundreds of thousands of exposed persons Table 102-3 Some Drugs and Chemicals Associated with Aplastic ... suppression as a major toxicity; effects are dose-dependent and will occur in all recipients In contrast, idiosyncratic reactions to a large and diverse group of drugs may lead to aplastic anemia...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 4) pptx
... monoubiquitination to play a role in the cellular response to DNA damage and especially interstrand cross-linking, a response that includes BRCA1, ATM, and NBS1 Dyskeratosis congenita is characterized by mucous ... half of patients with aplastic anemia at the time of presentation [and PNH cells are also seen in MDS (see below)]; frank hemolysis and thrombotic episodes occur in patients with large PNH clones ... Patients with Fanconi's anemia typically have short stature, café au lait spots, and anomalies involving the thumb, radius, and genitourinary tract At least 12 different genetic defects (all but one...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 5) pdf
... damage and death on exposure to certain chemical agents Telomeres are short in a large proportion of patients with aplastic anemia, and mutations in genes of the telomere repair complex (TERC and ... smear in aplastic anemia The marrow shows replacement of hematopoietic tissue by fat and only residual stromal and lymphoid cells An intrinsic stem cell defect exists for the constitutional aplastic ... bone marrow aspirate smear The marrow is normally 30–70% cellular, and there is a heterogeneous mix of myeloid, erythroid, and lymphoid cells C Aplastic anemia biopsy D Marrow smear in aplastic...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 6) ppt
... anemia patients and usually decline with successful immunosuppressive therapy; cytokine measurements show a T H1 immune response (interferon γ and tumor necrosis factor) Interferon and tumor necrosis ... restriction of symptoms to the hematologic system, and patients often feel and look remarkably well despite drastically reduced blood counts Systemic complaints and weight loss should point to other etiologies ... etiology of marrow failure Physical Examination Petechiae and ecchymoses are typical, and retinal hemorrhages may be present Pelvic and rectal examinations can often be deferred but, when performed,...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 7) docx
... of megakaryocytes and myeloid precursor cells, and typical cytogenetic abnormalities (see below) Prognosis The natural history of severe aplastic anemia is rapid deterioration and death Provision ... aplastic anemia is rapid deterioration and death Provision first of red blood cell and later of platelet transfusions and effective antibiotics are of some benefit, but few patients show spontaneous ... usefulness and glucocorticoids are of no value Suspect exposures to drugs or chemicals should be discontinued; however, spontaneous recovery of severe blood count depression is rare, and a waiting...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 8) potx
... relapse and malignant evolution Because of excellent results in children and younger adults, allogeneic transplant should be performed if a suitable sibling donor is available Increasing age and ... transfusion and a leukocyte count adequate to prevent infection) in about 50% of patients The addition of cyclosporine to either ALG or ATG has further increased response rates to about 70% and especially ... rates to about 70% and especially improved outcomes for children and for severely neutropenic patients Such combined treatment is now standard for patients with severe disease An early robust hematologic...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 9) docx
... (Chap 109), and neutropenia without marrow myeloid cells in agranulocytosis (Chap 61) In general, and in contrast to aplastic anemia and MDS, the unaffected lineages appear quantitatively and qualitatively ... or recrudescent fever implies fungal disease: Candida and Aspergillus are common, especially after several courses of antibacterial antibiotics, and a progressive course may be averted by timely ... incriminating drug exposure) and amegakaryocytic thrombocytopenia are exceedingly rare and, like PRCA, appear to be due to destructive antibodies or lymphocytes and can respond to immunosuppressive...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 10) pot
... aplasia (Diamond-Blackfan syndrome) Acquired pure red cell aplasia Thymoma and malignancy Thymoma Lymphoid malignancies (and more rarely other hematologic diseases) Paraneoplastic to solid tumors ... Systemic lupus erythematosus, juvenile rheumatoid arthritis, rheumatoid arthritis Multiple endocrine gland insufficiency Virus Persistent B19 parvovirus, hepatitis, adult T cell leukemia virus, EpsteinBarr ... azathioprine, chloramphenicol, procainamide, isoniazid Erythropoietin Idiopathic Clinical Associations and Etiology PRCA has important associations with immune system diseases A small minority of cases...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 11) docx
... production is not clinically apparent, and skin and joint symptoms are mediated by immune complex deposition Figure 102-2 Pathognomonic cells in marrow failure syndromes A Giant pronormoblast, the ... effect of B19 parvovirus infection of the erythroid progenitor cell B Uninuclear megakaryocyte and microblastic erythroid precursors typical of the 5q– myelodysplasia syndrome C Ringed sideroblast...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 12) pot
... (CMML) The (RAEB-t), World Health and chronic Organization classification (2002) recognizes that the distinction between RAEB-t and acute myeloid leukemia is arbitrary and groups them together as acute ... characterized by cytopenias associated with a dysmorphic (or abnormal appearing) and usually cellular bone marrow, and by consequent ineffective blood cell production A clinically useful nosology ... cyclophosphamide, and the monoclonal antibodydaclizumab, an antibody to the IL-2 receptor PRCA developing on erythropoietin therapy should be treated with immunosuppression and withdrawal of...
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Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes (Part 13) doc
... mutations, or other harmful alterations Cytogenetic abnormalities are not random (loss of all or part of 5, 7, and 20, trisomy of 8) and may be related to etiology (11q23 following topoisomerase II inhibitors); ... tel-PDGFβ gene The type and number of cytogenetic abnormalities strongly correlate with the probability of leukemic transformation and survival Mutations of N-ras (an oncogene), p53 and IRF-1 (tumor ... symptomatic patients complain of the gradual onset of fatigue and weakness, dyspnea, and pallor, but at least half the patients are asymptomatic and their MDS is discovered only incidentally on routine...
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