induction of tolerance using apoptotic cells in type 1 diabetes and other immune mediated disorders

Transplantation and improvement of mouse embryo progenitor derived insulin producing cells for type 1 diabetes therapy

Ngày tải lên : 11/09/2015, 09:58

... techniques……………………………………… 15 1. 2.5 .1 Ratinale of encapsulation of cells …………………………… 15 1. 2.5.2 Principle and application of encapsulation……………………… 16 1. 3 Roles of Maf A in -cell development and function.…………………… 19 1. 3 .1 ... cells ….………………… 11 3 4 .1. 5 Summary of transplantation of microencapsulated MEPI -1 cells … .11 6 4.2 Restoration of MafA in MEPI -1 cells ……………….……….……… 11 6 4.2 .1 Less-physical characteristics of MEPI -1 cells ………….……… 11 7 ... development and function including Insulin1, Insulin2, Pdx -1, NeuroD1, Nkx6 .1, Glut-2 and PC 24 Chapter Introduction 1. 3.6 Regulation of MafA According to the recent reports, the level of expression of...

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Báo cáo khoa hoc:" The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes" pptx

Ngày tải lên : 11/08/2014, 07:21

... (10 0) Yes ( 31) (46) (23) 13 (10 0) No 89 (22) (14 ) 41 (10 0) 11 1 (29) 18 1 (48) 86 (23) 21 (38) 25 (45) (16 ) 55 (10 0) 10 5 (29) 17 6 (48) 83 (23) (0) (10 0) (0) (10 0) 12 6 (30) 200 (48) 92 (22) 0.9 91 ... UAE (mg/24 h) 593 .1 (250.0 -15 19.5) 7.0 (4.0 -12 .0) p < 0.0 01 Plasma creatinine (μmol/l) 10 2 (82.0 -13 6.3) 79 (53- 81) p < 0.0 01 GFR (ml/min /1. 73 m2) 66 .1 ± 27.7 87.4 ± 14 .9 p < 0.0 01 ESRD (%male) 24 ... (43) 25 (22) 11 5 (10 0) No Mortality Cardiovascular (CV) death 17 0 ( 51) 77 (23) 46 (47) 23 (23) 98 (10 0) 97 (28) 17 4 (50) 79 (22) 350 (10 0) Yes 14 (40) 15 (43) (17 ) 35 (10 0) 11 2 (29) 18 6 (48) 86...

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Báo cáo y học: "Bilateral dystonia in type 1 diabetes: a case report" pot

Ngày tải lên : 11/08/2014, 19:21

... is mostly observed in type diabetes and cases with type diabetes are extremely rare In the 53 cases reported in the literature, only one case of type diabetes with acute onset of nonketotic hyperglycemia ... analyzed and interpreted the data regarding type I diabetes and MRI imaging AY and JW contributed to study concept and design, patient care, data analysis, literature review, and writing the manuscript ... stand and had had difficulties in taking meals for days These movements were observed in both waking and sleep states She presented extremely high plasma glucose (774 mg/dl), hemoglobin A1c ( 21. 2%)...

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Báo cáo y học: "Detection of poliovirus by ICC/qPCR in concentrated water samples has greater sensitivity and is less costly using BGM cells in suspension as compared to monolayers" pot

Ngày tải lên : 12/08/2014, 01:22

... [9] for a final volume of 20 mL Each sample was inoculated with 1% of 10 0X antibiotic/antimycotic and 0 .1% of 50 ug per mL of gentamicin sulfate and incubated at 37°C for hours Post incubation ... Suitability of infection of cells in suspension for detection of herpes simplex virus J Clin Microbiol 19 91, 15 54 -15 57 Reynolds KA, Gerba CP, Pepper IL: Detection of infectious enteroviruses by an integrated ... http://www.virologyj.com/content/7 /1/ 282 Page of Figure Comparison of ICC/q RT PCR cycle threshold (Ct) values of BGM monolayers infected with 10 PFU of poliovirus type (strain LSc -1) to similarly infected BGM suspensions in...

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Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"

Ngày tải lên : 25/10/2012, 10:02

... pre-existing increased insulin resistance and dysfunction of beta cells Insulin resistance is present in the acutely ill [13 ,15 ,18 ,28] in different intensity, but the factors determining the extent of ... Gregg EW, Bainbridge KE, Saydah SH, Geiss LS: Full accounting of diabetes and pre -diabetes in the U.S population in 19 88 -19 94 and 2005-2006 Diabetes Care 2009, 32:287-294 doi: 10 .11 86/cc 910 1 Cite ... resistance Curr Opin Clin Nutr Metab Care 2002, 5:5 51- 559 14 Marette A: Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings Curr Opin Clin Nutr Metab Care...

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Báo cáo y học: "Efficiency of vibration exercise for glycemic control in type 2 diabetes patients."

Ngày tải lên : 26/10/2012, 10:04

... [glucose] pretraining (mg / 10 0 ml) 12 0 ± 25 12 6 ± 23 13 3 ± 57 Plasma [glucose] posttraining (mg / 10 0 ml) 11 5 ± 22 12 0 ± 22 12 2 ± 35 Significance n.s n.s n.s HbA1C At baseline the HbA1c amounted ... conflict of interest exists 16 3 13 14 15 16 17 18 19 20 References Baum K, Rüther T, Essfeld D Reduction of blood pressure response during strength training through intermittent muscle relaxations Int ... al Strength training increases insulin -mediated glucose uptake, GLUT-4 content, and insulin signaling in skeletal muscle in patients with type diabetes Diabetes 2004; 53:294 - 305 10 Kasai T, Kawanishi...

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Production of hydrogen using composite membrane in PEM water electrolysis

Ngày tải lên : 05/09/2013, 16:11

... 10 0.0 95 90 85 80 75 10 21. 85 70 65 60 28 51. 47 55 %T 3 414 .19 50 29 21. 71 45 40 315 5.24 35 16 28 .15 30 15 38.93 25 10 58 .19 983.20 20 12 35.54 710 .55 15 11 52.98 10 532.00 655.36 14 00.05 635.77 0.0 4000.0 ... (cc/min) 6.45 12 .29 19 .92 24 .10 30.20 Current density (A/cm2) 0 .1 0.2 0.3 0.4 0.5 Time (min) 10 10 10 10 10 Voltage during electrolysis process (V) 27oC 45oC 65oC 1. 82 1. 75 1. 63 1. 9 1. 85 1. 75 2 .1 ... 24 .10 30.20 Current density (A/cm2) Time (min) 0 .1 0.2 0.3 0.4 0.5 10 10 10 10 10 Voltage during electrolysis process (V) 27oC 45oC 65oC 1. 85 1. 80 1. 75 1. 95 1. 90 1. 85 2 .15 2.05 1. 95 2.25 2 .14 ...

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Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx

Ngày tải lên : 21/02/2014, 15:20

... Aquarium Incubation period (h) ATP + ADP + AMP (%) Product (%) – – 1 10 10 10 – – 83.84 98.88 95.34 96. 61 97.78 98.78 97.80 98.90 16 .26 1. 12 4.66 3.39 2.22 1. 22 2.20 1. 10 1 10 10 10 – 98.48 96. 71 96.44 ... sponge, Geodia cydonium, Ó FEBS 2002 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 (2¢)5¢)Oligoadenylate synthetase in sponges (Eur J Biochem 269) 13 91 homolog of the human XPB/ERCC-3 excission DNA ... within amino acid 10 4 and amino acid 15 8 of the murine enzyme [53]; in S domuncula a related stretch has been found between amino acid 76 and amino acid 12 5 The polyA-related domain, found in...

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Prevalence of Celiac disease in Turkish children with type 1 Diabetes Mellitus and their non-diabetic first-degree relatives pptx

Ngày tải lên : 05/03/2014, 12:20

... 14 5.7 (28) 1. 9 (16 ) 0.25 (10 ) Diabetic children (433) Parent (8 71) and sibling (5 71) Control (347) 1. 6 (9) *

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Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot

Ngày tải lên : 07/03/2014, 16:20

... transport 1. 1 1. 8 0.6–0.7 0.9 1. 1 0 .1 0.2 1. 1 1. 8 0.6–0.7 0.3–0.4 0.02–0.03 1. 1 1. 8 1. 8–2.0 0.6–0.7 0 .1 0.2 1. 1 1. 8 1. 8–2.0 0.6–0.7 0 .1 0.2 1. 1 1. 8 1. 8–2.0 0.6–0.7 0 .1 0.2 1. 1 1. 8 1. 8–2.0 0.6–0.7 0 .1 0.2 ... Epinephrine-induced insulin resistance in man J Clin Inv 65, 717 –7 21 34 Rizza RA, Mandarino LJ & Gerich JE (19 82) Cortisolinduced insulin resistance in man: impaired suppresion FEBS Journal 272 (2005) 14 1 15 1 ... Japan) Using two-dimensional electrofocusing (pH 3 10 ), SDS ⁄ PAGE analysis [23] and immunoblotting against phosphotyrosine and IRS1, > 95% of the tyrosine phosphorylated 18 0-kDa band was determined...

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Báo cáo khoa học: Fatty acid composition of chylomicron remnant-like particles inﬂuences their uptake and induction of lipid accumulation in macrophages pot

Ngày tải lên : 16/03/2014, 12:20

... Atherosclerosis 13 9, 273–2 81 11 Proctor SD, Vine DF & Mamo JCL (2002) Arterial retention of apolipoprotein B48- and B100-containing lipoproteins in atherosclerosis Curr Opin Lipidol 13 , 4 61 470 12 Boren ... macrophages: determination of binding proteins Clin Sci 10 1, 11 1 11 9 5640 34 Peres CM, Homem de Bittencourt PI, Costa M, Curi R & Williams JF (19 97) Evidence for thr transfer in culture of [14 C]-labelled ... Skalen K, Flood C & Innerarity TL (2000) Role of extracellular retention of low 14 15 16 17 18 19 20 21 22 23 24 density lipoproteins in atherosclerosis Curr Opin Lipidol 11 , 4 51 456 Ghung BH, Talis...

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Báo cáo khoa học: An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase docx

Ngày tải lên : 23/03/2014, 17:21

... described in Materials and methods using GGPP as the allylic substrate Lane 1, mutant H139A; lane 2, mutant I136A/ H139A; lane 3, mutant L135A/H139A; lane 4, mutant L135A/I136A/ H139A; lane 5, wild type ... Identiﬁcation of 219 4 H Hemmi et al (Eur J Biochem 270) 10 11 12 essential amino acid residues for chain length determination of prenyltransferase reaction J Biol Chem 2 71, 18 8 31 18 837 Ohnuma, ... pET-HisScGG-H139S/ mutant H139S pET-HisScGG-H139A-3A/ mutant I136A/H139A pET-HisScGG-H139A-4A/ mutant L135A/H139A pET-HisScGG-H139A-3A4A/ mutant L135A/I136A/H139A For the construction of S solfataricus...

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báo cáo hóa học: " Fatness and fitness: how do they influence health-related quality of life in type 2 diabetes mellitus?" docx

Ngày tải lên : 18/06/2014, 19:20

... purposes) Health and Quality of Life Outcomes 2008, 6 :11 0 References 10 11 12 13 14 15 16 17 18 19 20 21 22 National Institute of Diabetes and Digestive and Kidney Diseases: National Diabetes Statistics ... (17 .9) 80.3 (14 .1) 84.3 (11 .7) 86.4 (13 .5) 87.7 (24.5) 89.3 (20.0) 93.3 (12 .9) 68.8 (16 .1) 51. 1 (5.6) 54.8 (6.9) Mean (SD) 74 (16 .4) 65.7 (17 .0) 82.0 (14 .2) 85.6 (14 .2) 84.7 (28.8) 82.8 (29 .1) ... recruited between 7 /1/ 99 and 11 /30/03 for the study in people without type diabetes and between 5 /1/ 04 and 12 /28/07 for the study in people with type diabetes Study design and sample This study...

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báo cáo hóa học:" Effects of TGF-β1 and IGF-1 on proliferation of human nucleus pulposus cells in medium with different serum concentrations" pptx

Ngày tải lên : 20/06/2014, 00:20

... disc cells, the structure and function of the degenerated cells changed remarkably Alini et al [11 ] observed an increase and maintain in density of bovine NP cells and synthesis Page of 11 (page ... of 10 10 0 μg/L IGF -1 in the presence of 10 % FBS Page of 11 (page number not for citation purposes) Journal of Orthopaedic Surgery and Research 2006, 1: 9 http://www.josr-online.com/content /1/ 1/9 ... the 10 μg/L TGF- 1 group ( 10 0) Figure 11 The morphology of human NP cells under 10 %FBS conditions The morphology of human NP cells under 10 %FBS conditions 10 %FBS, 10 μg/L TGF- 1+ 100 μg/L IGF -1, ...

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báo cáo hóa học:" Serous papillary adenocarcinoma possibly related to the presence of primitive oocyte-like cells in the adult ovarian surface epithelium: a case report" docx

Ngày tải lên : 20/06/2014, 08:20

... of Ovarian Research 2 011 , 4 :13 http://www.ovarianresearch.com/content/4 /1/ 13 round cells with diameters of to μm that express some markers of pluripotent stem cells and can develop in vitro into ... Vitro of Very Small Embryonic-Like Putative Stem Cells in Adult Mammalian Ovary Stem Cells Dev 2 011 11 Virant-Klun I, Skutella T: Stem cells in aged mammalian ovaries Aging (Albany NY) 2 010 , 2:3-6 ... 400× and 10 00×) Legend: brown-positive cells (Peroxidase/DAB) Scale bar: 10 0 μm Page of of birth control, and defects in the BRCA1 or BRCA2 genes Unfortunately, in most women ovarian serous carcinoma...

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báo cáo hóa học:" Misinterpretation with norm-based scoring of health status in adults with type 1 diabetes" ppt

Ngày tải lên : 20/06/2014, 15:20

... 20. 91 (12 .43) 12 .0 210 214 89 (42.2) 10 1 (47.9) 21 (10 .0) 19 5 (92.9) 4.0 (1. 0–5.0) 215 213 215 214 88 (40.7) 73 (33.8) 55 (22.5) 40 (18 .5) 216 216 216 216 216 82 (38.0) 56 (25.9) 44 (20.4) 34 (15 .7) ... (19 .9) 41 (19 .0) 27 (12 .5) 40 (8.5) (3.2) 216 12 6 (58.3) 11 (5 .1) 18 (8.3) 30 (13 .9) 16 (7.4) 15 (6.9) 19 6 19 (9.7) 44 (22.4) 37 (18 .9) 36 (18 .4) 60 (30.6) *n (%) unless otherwise specified [10 ] ... Household Income Last Year ≤ $10 000 $10 000 – 29 999 $30 000 – 49 999 $50 000 – 69 999 ≥ $70 000 n Total* 215 216 37 .13 (14 .28) 12 7 (58.8) 216 69 ( 31. 9) 13 1 (60.6) 13 (6.0) (1. 4) 216 16 (7.4) 42 (19 .4)...

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RECENT ADVANCES IN THE PATHOGENESIS, PREVENTION AND MANAGEMENT OF TYPE 2 DIABETES AND ITS pptx

Ngày tải lên : 28/06/2014, 05:20

... topic of diabetes and fibrinolysis, including evidence for plasminogen activator inhibitor -1 as a predictor of cardiovascular risk in type diabetes Yaturu and Mousa discuss evidence for aspirin ... Diagnosis of diabetic peripheral neuropathy among patients with type and type diabetes in France, Italy, Spain, and the United Kingdom Prim Care Diabetes, Vol 1, No 3, pp 12 9 -13 4 14 Recent Advances in ... probabilities (w1 and w2) and mean levels ( 1 and 2) for classes C1 and C2, respectively, are given by ｔ w1 = pi , (2) i =1 L pi , w2 = (3) i=t +1 and ｔ 1 = ipi/w1 , (4) i =1 L μ2 = ipi/w2 (5) i=t +1 Otsu...

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Báo cáo khoa học: "An immunohistochemical study of the gastrointestinal endocrine cells in the ddY mice" doc

Ngày tải lên : 07/08/2014, 17:22

... situated in that regions mixed with close-typed cells similar to that of gastrin-IR cells (Fig 3c, d) Open and close typed cells were Gastrointestinal endocrine cells of ddY mouse 91 and ileum ... pp 81- 119 , SpringerVerlag, Berlin, 19 83 11 Fujita T, Kanno T, Kobayashi S The paraneuron pp 12 86, Springer, New York, 19 88 12 Grube D, Yoshie S Immunohistochemistry of chromogranin A and B, and ... Parasitology 19 92, 30, 16 9 -17 5 17 Kitamura N, Yamada J, Calingasan YN, Yamashita T Immunocytochemical distribution of endocrine cells in the gastro-intestinal tract of the horse Equine Vet J 19 84, 16 , 10 3 -10 7...

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Báo cáo khoa học: " Changes of gastrointestinal argyrophil endocrine cells in the osteoporotic SD rats induced by ovariectomy" ppt

Ngày tải lên : 07/08/2014, 17:23

... stains in the study of endocrine cells of the gut and pancreas Invest Cell Pathol 19 80, 3, 3 -12 12 Kalu DN The ovariectomized rat model of postmenopausal bone loss Bone Miner 19 91, 15 , 17 5 -19 1 13 ... 3.24, 51. 20 ± 12 .33 and 67.90 ± 15 .60 cells, respectively In OVX, argyrophil cells were detected with 75.90 ± 19 .26, 56.20 ± 9.98, 12 .20 ± 3.29, 9 .10 ± 1. 66, 9 .10 ± 2.20, 12 .10 ± 3.78, 21. 10 ± ... Elucidation of the changes of individual GI endocrine cells using immunohistochemistry [24] and/ or change of argentaffin cells using another silver technique will provide mechanisms for understanding...

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Báo cáo khoa học: "Changes of gastrointestinal argyrophil endocrine cells in the COLO205 tumor-implanted Balb/c-nu/nu mice" pps

Ngày tải lên : 07/08/2014, 18:21

... 00 01/ sllec 27.2 ± 06 .11 dna 20.3 ± 07.5 ,97.0 ± 02.2 ,97.0 ± 08 .1 ,28.0 ± 03.2 ,27 .1 ± 05.6 ,62. 41 ± 00.42 ,25.7 ± 02 .14 htiw detceted erew sllec lihporygra ,502OLOC nI ylevitcepser ,sllec 31. 6 ... lihporygra ,502OLOC nI ylevitcepser ,sllec 31. 6 ± 03. 61 dna 63.5 ± 07.32 ,93.2 ± 02.5 ,99.0 ± 09 .1 ,29.0 ± 02.2 ,75 .1 ± 03. 01 ,18 .32 ± 06 .12 1 ,56. 41 ± 03.86 htiw mutcer dna noloc ,mucec ,mueli ,munujej ... 072-342 ,37 86 91 spU deM coS atcA stelsi citaercnap namuh ni sllec-2á rof gniniats etartin revlis A L suilemirG 11 19 2-782 ,9 41 ,68 91 lohtaP J amonicraconeda dna sitiloc evitareclu ni mutcer eht fo...

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