incorporating novel agents with chemotherapy and radiotherapy for the treatment of locally advanced squamous cell carcinoma of the head and neck

Báo cáo khoa học: "Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities" doc

Ngày tải lên : 09/08/2014, 07:21

... involving the parotid gland Head Neck 2001, 23:744-748 Joseph MG, Zulueta WP, Kennedy PJ: Squamous Cell Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome ... (63.6%) were T3 and (36.4%) were T4 Nine were submitted to lymphadenectomy, 01 was treated with radiotherapy and 01 refused treatment The treatment of choice of the primary tumor was radiotherapy in ... most of them are heterogeneous or include also initial stage lesions and head and neck tumors [1016] The present study investigates a consecutive series of only localized advanced SCCS of the...

6
300
0

Báo cáo khoa học: "Normalization of prostate specific antigen in patients treated with intensity modulated radiotherapy for clinically localized prostate cancer" pot

Ngày tải lên : 09/08/2014, 09:20

... relationship between the rate of normalization of PSA and the duration of NAAD therapy Previous studies have attempted to determine the optimal duration of androgen deprivation therapy for men with clinically ... obtained the retrospective data from the charts, and wrote the first draft of the paper GDAP and PC conceived of the study, and participated in its design and coordination and helped to draft the ... Soloway MS: Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: A randomized comparative trial of the Radiation Therapy Oncology...

6
323
0

Báo cáo khoa học: "Prior surgical intervention and tumor size impact clinical outcome after precision radiotherapy for the treatment of optic nerve sheath meningiomas (ONSM)" docx

Ngày tải lên : 09/08/2014, 09:21

... complained of new headaches, and three of recurrent hyperlacrimation of the irradiated eye, one with change of taste perception None of the patients developed dysfunctions of the pituitary gland, neuropathy, ... Several groups have reported their clinical results of precision radiotherapy for the treatment of ONSM Figure Correlation of PTV-size and visual outcome Patients with smaller treatment volumes were ... Kuhn and her team of technicians for excellent patient care Authors’ contributions SC, JD and SR treated the patients SA, SR and SC collected the data SC and SA evaluated the dataset and performed...

6
327
0

Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx

Ngày tải lên : 14/08/2014, 07:21

... Resau J, Bradford C, Carey T, et al.: Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients ... Determination of the regulation of these genes will require further study of the potentially complex contribution of expression, phosphorylation, and co-factor interaction of wild-type and p53 mutants, and ... applications of microarrays in head and neck cancer research Laryngoscope 2004, 114:241-248 Choi P, Chen C: Genetic expression profiles and biologic pathway alterations in head and neck squamous cell carcinoma...

25
349
0

Báo cáo khoa học: Alternative splicing produces an H-protein with better substrate properties for the P-protein of glycine decarboxylase doc

Ngày tải lên : 23/03/2014, 04:20

... part, to the small amounts of pea H-protein introduced into the assay with the mitochondrial extracts Notably, the Vmax values were signiﬁcantly higher with FtGLDHAA than they were with FtGLDH, ... N-terminus of the H-protein In conclusion, the substrate properties of the alternatively encoded Flaveria H-protein FtGLDHAA in the P-protein reaction of GDC differ signiﬁcantly from those of the normal ... criteria of integrity Methods Enzymol 148, 403–420 32 Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye...

7
394
0

Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Ngày tải lên : 18/06/2014, 19:20

... cisplatin is the backbone of the chemotherapy regimen as a component of IC and CCRT in the treatment of locally advanced HNSCC Its main cytotoxic activity is based on the formation of DNA adducts, ... DE, Forastiere AA: An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck ... L: Chemotherapy added to locoregional treatment for head and neck squamous- cell carcinoma: three meta-analyses of updated individual data MACH-NC Collaborative Group Meta-Analysis of Chemotherapy...

8
689
0

**AUDIT TOGETHER WITH INDEPENDENT AUDITORS* REPORT FOR THE PERIOD JULY potx**

Ngày tải lên : 18/06/2014, 20:20

... affect the reported amounts of assets and liabilities and disclosures of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and. expenses ... estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported ... without cost, services for the administration of the Foundation in the form of personnel costs, rent, utilities, and the use of office equipment These services are valued at their actual cost to Grambling...

14
271
0

Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot

Ngày tải lên : 18/06/2014, 22:20

... Cullen KJ: Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: evolution of a model beyond TNM staging Curr Opin ... value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent head and neck cancer Head Neck 2000, 22:599-608 33 Werkmeister R, Brandt B, Joos U: Clinical relevance of erbB-1 ... Renginfo E, et al: Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients...

10
490
0

báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Ngày tải lên : 20/06/2014, 03:20

... cisplatin is the backbone of the chemotherapy regimen as a component of IC and CCRT in the treatment of locally advanced HNSCC Its main cytotoxic activity is based on the formation of DNA adducts, ... DE, Forastiere AA: An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck ... L: Chemotherapy added to locoregional treatment for head and neck squamous- cell carcinoma: three meta-analyses of updated individual data MACH-NC Collaborative Group Meta-Analysis of Chemotherapy...

8
428
0

báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc

Ngày tải lên : 20/06/2014, 04:20

... Cullen KJ: Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: evolution of a model beyond TNM staging Curr Opin ... value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent head and neck cancer Head Neck 2000, 22:599-608 33 Werkmeister R, Brandt B, Joos U: Clinical relevance of erbB-1 ... Renginfo E, et al: Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients...

10
479
0

Báo cáo hóa học: " Unscented Kalman filter with parameter identifiability analysis for the estimation of multiple parameters in kinetic models" pptx

Ngày tải lên : 20/06/2014, 22:20

... sensitivity to the system output and then which of the parameters are linearly independent The method iterates over the columns of the sensitivity matrix Z to select the column with the highest sum of squared ... were performed for each of these methods The comparison of the parameter estimation methods is presented in Table and Figure In each case, the mean and standard deviation are calculated for the 97 ... based on the model structure and the measurement data One of the benefits in integrating estimation and identifiability is the reuse of the variance generated by the UKF for the step size in the calculation...

8
381
0

Báo cáo hóa học: " A New MAC Protocol with Pseudo-TDMA Behavior for Supporting Quality of Service in 802.11 Wireless LANs" docx

Ngày tải lên : 22/06/2014, 22:20

... calculate the behavior of the proposed model in comparison with EDCA The performance of the MAC protocols is tested for variable number of contending stations, basic and handshaking access, and the ... classes and a reserved bandwidth for low-priority classes by means of an admission algorithm The model is designed to be backward compatible with the other 802.11 protocols The rest of the paper ... University of Thessaloniki, and in the year 1984 got his Diploma in electrical and computer engineering from the University of Patras He did his postgraduate studies in the University of Bradford in the...

9
428
0

Báo cáo hóa học: " ITERATIVE SCHEMES WITH SOME CONTROL CONDITIONS FOR A FAMILY OF FINITE NONEXPANSIVE MAPPINGS IN BANACH SPACES" docx

Ngày tải lên : 23/06/2014, 00:20

... et al 127 In general, the control conditions (1.6) and (1.7) are not comparable (coupled with conditions (1.2) and (1.3)), that is, neither of them implies the others as in the following examples ... [21, 23], and others for N = 1, respectively Remark 3.5 (1) Our proof lines of Theorem 3.1 are diﬀerent from those of Zhou et al [24], in which, as in [19, 23], they utilized the concept of Banach’s ... (1.2), (1.3), and (1.8) Then the iterative sequence {xn } deﬁned by (1.1) converges strongly to QF a, where Q is a sunny nonexpansive retraction of C onto F Proof As in the proof of [1, Theorem 1],...

11
305
0

báo cáo khoa học: "Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: clinical experience and review of literature" ppsx

Ngày tải lên : 09/08/2014, 02:20

... upon the need for close surveillance regardless of the SLN status This study and review of literature highlights the potential limitations of SLN biopsy for SCC and the critical importance of careful ... recurrence; SCC: squamous cell carcinoma; SLN: sentinel lymph node Acknowledgements The authors wish to thank Drs Noel Weiss and Thomas Lumley for their helpful review of the epidemiological and analytical ... contributions SK did the data collection and data analysis, reviewed the literature, and wrote the manuscript ZD provided the pathology figures and legends PW wrote the manuscript and supervised the work...

7
366
0

Báo cáo khoa học: "Large volume unresectable locally advanced nonsmall cell lung cancer: acute toxicity and initial outcome results with rapid arc" potx

Ngày tải lên : 09/08/2014, 09:20

... and two grade 2) who underwent concurrent chemo -radiotherapy at 45 days from the end of treatment and regressed with antibiotic therapy, without hospitalization Compared with exclusive radiotherapy ... [26] the motion of these lesions is lower than mm, therefore the use of 4D techniques is unnecessary Furthermore daily kV-cone beam CT (CBCT) is performed before RT treatment in order to verify the ... received by the x% of the volume; Vx% = volume receiving at least x% of the prescribed dose; CI = ratio between the patient volume receiving at least 95% of the prescribed dose and the volume of the...

9
265
0

Báo cáo khoa học: "Recurrence patterns of locally advanced head and neck squamous cell carcinoma after 3D conformal (chemo)-radiotherapy" pdf

Ngày tải lên : 09/08/2014, 09:20

... results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced- stage oropharynx carcinoma ... treated with a combination of chemotherapy and radiotherapy Of these 115 patients, 42 (36.5%) patients were treated with induction chemotherapy followed by radiotherapy, 63 (54.7%) patients with ... of radiotherapy, and of these patients experienced in-field recurrences of the total of 20 cases of LRR occurred in the group of patients who had had a less than CR to nonsurgical treatment and...

11
308
0

Báo cáo khoa học: "Parotid gland-recovery after radiotherapy in the head and neck region: 36 months follow-up of a prospective clinical study" pdf

Ngày tải lên : 09/08/2014, 09:21

... in terms of parotid gland sparing The IMRT technique should therefore represent the standard of care for the treatment of head and neck tumors Parotid-gland-sparing up to mean doses of 26 Gy ... NL) The planning strategy was to cover 95% of the PTVs with 95% of the prescribed dose The mean dose of at least one parotid gland was limited to 26 Gy without compromising the PTV, and the maximum ... mention the expected anatomical changes of the parotid glands during the head and neck irradiation [29] This is known from studies in centers with the use of helical tomotherapy Due to weight loss and...

25
342
0

Báo cáo khoa học: "Intensity-Modulated Radiotherapy for Squamous Cell Carcinoma of the Anal Canal: Efficacy of a Low Daily Dose to Clinically Negative Regions" ppsx

Ngày tải lên : 09/08/2014, 09:21

... Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for ... cancer; chemotherapy; intensity-modulated radiotherapy; squamous cell carcinoma Introduction Fluorouracil (FU) and mitomycin C (MMC) combined with radiotherapy is the standard treatment for squamous ... compared with MMC (94%), and the need for a colostomy was similar between groups Currently, radiotherapy delivered concurrently with FU and MMC remains the standard of care for squamous cell carcinoma...

19
374
0

Báo cáo khoa học: " Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans" ppsx

Ngày tải lên : 09/08/2014, 10:21

... Pierart M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a Page 10 of 11 (page number not for citation purposes) ... fractions The mean dose to the femoral head was 58.3% and 59.5% of the prescription dose for their patients using conformal avoidance IMRT Similarly, the mean dose to the femoral head with the IMRT ... toxicity with an iliac crest V20 of 59% and V10 of 73% It is possible that sparing of the femoral heads and/ or other organs comes at the cost of increasing dose to the iliac crests The results of...

11
402
0

Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps

Ngày tải lên : 09/08/2014, 14:20

... interpretation of the data, and critiquing of drafts of this article BB was involved in the design of this project, analysis and interpretation of the data, and critiquing of drafts of this article ... interpretation of the data, and drafting of this article IO was involved in the conception and design of this project, analysis and interpretation of the data, and critiquing of drafts of this article ... content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Arthritis and Musculoskeletal and Skin Diseases or the National...

7
405
0