in vitro in vivo correlation of the causal relationship between cigarette smok ing and higher incidence of carcinomas
The dynamic relationship between commercial real estate and stock markets
... economic drivers and the major users of 11 Chapter Introduction the office buildings The majorities of the office buildings in Singapore are held under single ownership by financial institutions ... cost, land availability and cost and cost of capital, together with the macroeconomic shocks indicating the extent of bank and institutional lending, would determine the rate and the extent of real ... Examine the causal relationship between the office and the stock markets Both linear and nonlinear Granger causality tests are used to assess the causal relationship between the two markets Causal...
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Báo cáo khoa học: Insertion of the plant photosystem I subunit G into the thylakoid membrane In vitro and in vivo studies of wild-type and tagged versions of the protein doc
... harvesting complex (LHCI), consisting of four members (Lhca1–4) of the chlorophyll a ⁄ b binding protein family LHCI is bound along one side of PSI only, in the vicinity of the PSI-F and PSI-J ... plants expressing similar levels of PSI-G, and analysed by immunoblotting, using antibodies to PSI-G and PSI-F, as an indicator of the relative content of PSI in the samples Plants lacking PSI-G ... conformation of the loop His-tags were employed in a topological study of the major light harvesting chlorophyll a ⁄ b binding apoprotein, Lhcb1 [18] Interestingly, fusion of a His-tag to the C-terminus,...
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báo cáo khoa học: " In vivo reorganization of the actin cytoskeleton in leaves of Nicotiana tabacum L. transformed with plastin-GFP. Correlation with light-activated chloroplast responses" potx
... positioning in higher land plants The striking recovery of wortmannin-inhibited movements obtained with Ca2+ shows that these ions play at least two roles in the mechanism of the movements: they ... (Ca+2) and in control (Ctrl)+2) ions the presence of Thickness of actin bundles magnesium (Mg and in Thickness of actin bundles in control (Ctrl) and in the presence of calcium (Ca+2) and magnesium ... actin bundles It might be a result of some yet undefined interaction between filaments (or between actin and ABPs) in SL, leading to the formation of looser bundles The differences between the...
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Báo cáo y học: "Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis" doc
... subcutaneously injected with 20 μg of CII/20 μl of PBS in the right ear and with 20 μl of PBS in the left ear DTH response was calculated as the percentage swelling (the difference between the increase of ... molecules candidate mediators of T-cell inhibition The involvement of iNOS and COX-2 in inhibition of T-cell proliferation was demonstrated by the addition of inhibitors of these enzymes - GW274150 and ... assessed the effect of MSCs on in vitro and in vivo T-cell proliferation as well as on CIA By using MSCs of both IFN-gR KO and wild-type origin, we also addressed the role of IFN-g in the immunomodulatory...
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Báo cáo khoa học: "Comparative study on the in vitro and in vivo properties of two bovine herpesvirus-5 reference strains" pptx
... this point, a direct comparison of the pathogenecity of these strains is difficult to make In this context, the aim of the present study is to compare the in vitro and in vivo properties of these ... 1) All the animals infected with A663 strain shed virus, three of them excreted during 5-13 days and the remaining one showed intermittent excretion (Table 1) The profiles of viral shedding were ... having an impact on the in vitro behavior of both BoHV-5 strains Concerning the in vivo characterization, in spite of the in vitro differences discussed above, we observed that both BoHV-5 strains...
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In vitro and in vivo studies into the antidiabetic and antilipidemic effects of chlorogenic acid
... stimulus to the regulation of various cellular processes usually involves protein kinase signaling Insulin signaling is initiated upon the binding of the hormone to its receptor which triggers the conformational ... kidney, muscle and adipose tissue Activation of insulin signaling upon binding of insulin to insulin receptors causes suppression of gluconeogenesis in liver and kidney [14], translocation of glucose ... [24] VI Incretins Incretins are hormones secreted by intestine in response to nutrients ingestion Their main effect is to stimulate pancreas to release insulin after meals intake Two incretin hormones...
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Tài liệu Báo cáo Y học: Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL pptx
... of this family including UspA itself (Fig 2), and one larger protein consisting of two UspA domains in tandem [17] The small members of this family are proteins of 142–144 amino-acids long; they ... ratio between the amounts of UP12 and the total amount of protein in the extracts, a series of samples containing determined amounts of the purified UP12 were separated by SDS/PAGE along with the ... Department of the Weizmann Institute by a single injection of 150 lg of the purified protein, followed by two booster shots of the same amount of protein at 2-week intervals Serum was collected and used...
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Báo cáo khoa học: A steady-state modeling approach to validate an in vivo mechanism of the GAL regulatory network in Saccharomyces cerevisiae ppt
... that controls the protein expression in the wild-type is the shuttling of Gal80p Increasing the amount of Gal80p in the cytoplasm by increasing the distribution coefficient (K) causes the switch ... to the response of a regulatory network for a given input For example, the operation of the switch is constrained by the number of binding sites and the amounts of regulatory proteins Further, ... protein, whereas, Gal80p is present both in the nucleus and in the cytoplasm [11,23] The above two studies indicate the existence of following two contrasting in vivo mechanisms for GAL protein...
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Báo cáo khoa học: A mouse model for in vivo tracking of the major dust mite allergen Der p 2 after inhalation docx
... Sel-tag had an intact core sequence and maintained allergen-specific IgE-binding epitopes and the use of a Sel-tag enabled labelling with the gamma-emitting radionuclide 75Se at a single predefined ... application of a newly developed technique for specific labelling of recombinant proteins by means of incorporating a radioactive selenocysteine residue in a C-terminal Sel-tag [18] Der p carrying the ... mimicking inhalation of the natural allergen The fact that i.t instillation of [75Se]Der p led to deposition of radioactivity in alveoli and bronchioli with no detectable allergen remaining in the...
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Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot
... calpain degradation Results Levels of HSP90 and NOS isozymes in rat brain and aorta The level of HSP90 and the type of NOS isoform present in rat brain and aorta were determined by immunoblotting ... vivo degradation of NOS and HSP90 by calpain higher than in aorta, resulting in a much higher HSP90 to NOS ratio in brain (Fig 1C) A Calpain activation in rat brain and aorta following HSD treatment ... resulting in an imbalance within the proteolytic system [32]; and (c) the degradation of calpain target proteins [26,30] As shown in Fig 2A, following HSD treatment, the levels of both l- and milli-calpain...
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báo cáo hóa học:" In vivo properties of the proangiogenic peptide QK" pdf
... http://www.translational-medicine.com/content/7/1/41 QK performing ex vivo experiments of vascular reactivity in WKY common carotid rings [12], and then we evaluated in vivo the role of this small peptide studying the ... hematoxylin and eosin [4] Quantitative analysis was done by counting the total number of endothelial cells, identified by lectin staining (see immunohistology), in the Matrigel plug in each of 20 randomly ... Journal of Translational Medicine 2009, 7:41 new capillaries) and arteriogenesis (enlargement and remodeling of pre-existing collaterals) [2] In detail, the term angiogenesis refers to the sprouting,...
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Báo cáo hóa học: " In vivo evidence of htid suppressive activity on ErbB-2 in breast cancers over expressing the receptor" potx
... demonstrating the inverse correlation of the expression of the two tumor relevant molecules and implying their functional link Discussion The understanding of the mechanism responsible for the in vivo ... murine receptor resulted in a faint stain of the cytoplasm and rarely in staining of the membrane of the tumor cells (Figure 3B) In the more advanced 30 weeks tumors the staining patterns changed ... pathways by binding and modifying functions of key molecules maintaining intracellular signalling The ErbB-2 TRK represents one of these molecules As revealed by the RT-PCR analysis, the three htid...
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báo cáo hóa học:" Function of anterior talofibular and calcaneofibular ligaments during in-vivo motion of the ankle joint complex" docx
... each testing position of AJC motion There was no bony interference with the path of the ATFL and CFL The position of the AJC during MR scanning was defined as the neutral reference position The length ... the understanding of function of these ligaments and injury mechanisms However, the in- vivo behavior of the lateral ankle ligaments during the range of motion has not been well studied Data in ... applying inversion/eversion and internal/external rotational forces during the flexion-extension arc of motion They demonstrated increased strain in the ATFL with increasing plantarflexion, inversion...
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báo cáo hóa học:" In vivo evaluation of a vibration analysis technique for the per-operative monitoring of the fixation of hip prostheses" pdf
... insertion stages and canal and reinserting the prosthesis The FRF had a normal evolution during the reinsertion and the graphs corresponding to the final two stages, labelled as stage 4a and stage 5a, ... 288D01) mounted between the shaker and the stinger The stinger is a slender rod threaded at both ends, one of them being connected to the impedance head and the other one to a Page of 10 (page number ... as single bending of the femur shaft The higher frequency resonances correspond to more intricate deformation modes of the femur in combination with deformation modes of the prosthesis In the...
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Báo cáo hóa học: " Assessment of the In Vivo Toxicity of Gold Nanoparticles" pdf
... serum albumin (BSA) and incubating for 60 at room temperature, followed by three PBS washes Binding was performed by adding 100 lL of diluted antiserum into microwells and incubating for h at ... -azino-di-(3-ethylbenzthiazoline sulfonic acid) (ABTS) and H2O2 were added in sequence to the wells according to the manufacturer’s protocol, and the binding efficiency was monitored by measuring ... underneath had minor rashes, bruising, and hemorrhaging Starting from day 14, mice injected with 8–37 nm GNPs showed a significantly camel-like back and crooked spine The majority of mice in these groups...
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Screening of Bacillus strains as potential probiotics and subsequent confirmation of the in vivo effectiveness of Bacillus subtilis MA139 in pigs doc
... of spore-forming bacteria used as probiotics and then evaluate the strain of Bacillus showing the greatest in vitro potential for its effectiveness in improving piglet performance and faecal flora ... analysis for the counts of lactobacilli and E coli according to the methods of Mikkelsen et al (2003) Faeces from the negative control and the diet containing spores that performed best during the performance ... through the small intestine (Huang and Adams 2004) The experimental results of Casula and Cutting (2002) suggest that B subtilis germinates in the jejunum and ileum The adverse conditions in the...
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Báo cáo toán học: "OXIDATIVE PHOSPHORYLATION: Kinetic and Thermodynamic Correlation between Electron Flow, Proton Translocation, Oxygen Consumption and ATP Synthesis under Close to In Vivo Concentrations of Oxygen" docx
... Fourth, to 10 μl of standard medium containing from to 400 nmols of ADP were added into the cell and the system again incubated until the O2 and ATP (contaminating the sample of ADP) added Oxygen ... molar ratio between O2 and protein Thus, when the concentration of protein is increased maintaining constant the concentration of O2, the energy directly involved in the synthesis of ATP is substantially ... amount of ATP formed at the moment the net synthesis of ATP ceases was determined by measuring the distance between the base line and the top of the trace (see Figs 1b and 2) This distance was then...
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Báo cáo y học: "Application of in vivo microscopy: evaluating the immune response in living animals" pps
... mobility in lymph nodes of living animals breathing either room air or 95% O2/5% CO2 In contrast, manipulations involved in the intravital approach including the trauma associated with anesthesia and ... resident DCs are labeled in the skin by injecting CSFE together with antigen and adjuvant CSFE+ DCs are then detected after migration in the draining lymph nodes and the interaction with antigenspecific ... kind of accompanying studies in vitro will certainly provide a deepening understanding of the complex cellular choreography that is required for the initiation of a coordinate and appropriate...
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Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt
... administered during the most active stage of disease [29] The discrepancy between the two studies could be due to a number of factors, including the longevity of the injected protein and the level of free ... antibody (Pharmingen-Becton Dickinson) Staining was performed in the presence of saturating concentration of 24G2 monoclonal antibody (anti-FcγRII/III) Data were analysed using WinMDI software (version ... of the DNase I present in the supernatants purified as in (b) The activity was determined in the presence of the normal DNA-MG assay buffer, described in Materials and methods, or following the...
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Báo cáo khoa học: "The in vivo study on the radiobiologic effect of prolonged delivery time to tumor control in C57BL mice implanted with Lewis lung cancer" pdf
... irradiation [16] To explain the discrepancy between the in vitro and in vivo results, Tomita N et al conducted another in vivo study to evaluate the effect of intermittent radiation by using local irradiation ... irradiated the tumor cancer cells simulating the IMRT plans They delivered a total dose of Gy to the cell lines over min, and 20 min, and found that compared with the and group, the survival fraction of ... largely from in vitro rather than in vivo observations, thus does not consider that tumor response in vivo are affected by other effects such as the impact of ionizing radiation on the supporting tissues...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25