... with DAPK methylation datawas small, and hence the statistical power ofthe analysis was diminished. Therefore, the role of DAPK me thyla-tion in myeloma warrants further study with largernumber ... patients.Authors’ contributionsCSC is responsible for the conception, design, and acquisition of data, analysis and interpretation of data, writing and approval ofthe manuscript.Competing interests The ... The protocol was approv ed by the institution review board in accordance with the Declaration of Helsinki, and informedconsent was obtained from all participating patients. The treatment algorithm was...
... that Akt is importantin mediating the effects of FSH on inhibin -A, activin -A, oestradiol and progesterone secretion and also important in mediating IGF-I stimulated inhibin -A, activin -A, follistatin, ... actions ofthe Akt pathway are more pronouncedthan the Erk pathway in granulosa cells and vice versa in thein theca cells. None the less, administration of inhibi-tors of these pathways in vivo inhibited ... mediator of gonadotropinaction, these hormones also activate other signalling path-ways that include activation ofthe Erk pathway [9,10], the Akt pathway [11,12] and the inositol triphosphate...
... Member States at both national and international levels by providing them with assistance, resources and the training required for meaningful and sustainable involvement in all aspects ofthe process”. ... RepublicDenmarkEstoniaFinlandFranceGeorgiaGermanyGreeceHungaryIcelandIrelandIsraelItalyKazakhstanKyrgyzstanLatviaLithuaniaLuxembourgMaltaMonacoMontenegroNetherlandsNorwayPolandPortugalRepublic of MoldovaRomaniaRussian FederationSan MarinoSerbiaSlovakiaSloveniaSpainSwedenSwitzerlandTajikistan The ... www.euro.who.intMember StatesAlbaniaAndorraArmeniaAustriaAzerbaijanBelarusBelgiumBosnia and HerzegovinaBulgariaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGeorgiaGermanyGreeceHungaryIcelandIrelandIsraelItalyKazakhstanKyrgyzstanLatviaLithuaniaLuxembourgMaltaMonacoMontenegroNetherlandsNorwayPolandPortugalRepublic...
... in part to the breadth of this topic, it was also due to the fact that spatialanalysisof archaeo-logical materials has been recognized as being one of the mostimportant ways of gaining insights ... considerable interest in this aspect of spa-tial analyses ofthe material remains of past cultures.As functionalism gave way to processualism as the prevailing paradigm in archaeology inthe Americas, ... the archaeological record. In short, spatialanalysisin archaeology is rel-evant to scholars pursuing all sorts of “higher level” theoretical questions, insofar as thespatialanalysisof archaeological...
... theanalysisofthe current performance of English teaching and learning in JHSs in Quang Ngai province. Time and efforts have been spent on accumulating information about teachers and teaching ... process of change in language teaching.1 • The Functional-Notional Approach In the 1970s teachers ofthe Functional-Notional Approach stopped teaching grammar and started teaching more practical ... ADAPTING THE DIALOGUE TO THEIR LIVES.(Using prompts)Explain to the students that they are going to do the dialogue again in pairs, using their own information. This time the teacher is going...
... attention and encouragement.I am appreciative of all those who have kindly advised and helped me during the period of my study at College of Foreign Languages, VNU-Hanoi.Finally, I wish to thank ... Personal Information 9ã Age of teachers 9ã Teaching experience and training 9ã Qualifications 10 2.6.2.2. Information about Schools 10ã Access to resource at school 10ã Conditions that facilitate ... VNU-Hanoi for their enthusiastic support.I am sincerely grateful to Mr. Đinh Tấn Bảo and my colleagues of Foreign Languages Department, Quang Ngai Teachers Training College for their attention...
... years which explains the fact that the available data dates back to 1996. A cross-country comparison ofthe innovation indicators can help identify national strengths,and areas of weaknesses that ... are taken into account in evaluating the trade-offs in devising legislation.Whatever is good for enterprise policy is generally good for innovation, and vice versa. Thisapplies in particular ... that dominate the economy. This is apparent inthe high innovative capacity of Sweden, Finland and Ireland and the low innovative capacity of Greece and Portugal. Of course, this shift towards...
... between the onset of cough and a new consultation according to the categor-ies ofthe variables that remained inthe final multivari-ate model (Table 3).Table 1 Univariate analysisofthe factors ... pulmonary TB in HIV-infected individuals.When this time interval was greater than the median itwas assumed that a delay in initiating treatment hadtaken place and that it was related to the health ... twostages. Inthe first, a multivariate regression analysis wasundertaken in each group, starting with a minimal modeland adding one variable at a time. Variables associated totreatment delay...
... com-plex, indicating that the interaction between VBARPand Vpr is specific. The input panel represents the amount of protein used in this assay indicating that anequal amount of protein was used in all ... Protein Analysis System predicted thatthis protein belongs to the family of ankyrin repeatproteins (Fig. 2C). Comparative analysisof VBARPankyrin repeats with other known ankyrin repeatproteins, ... found inthe protein database. The ankyrin repeat isa 33-amino acid motif present in repeats of 12–24 and first identified in yeast andDrosophila [1]. Ankyrin-repeat-containing proteinsregulate...
... techniquesto analyse dynamic mechanisms and measures of crosstalk.We illustrate our approach by giving an example of twosignalling pathways inthe budding yeast Saccharomycescerevisiae, i.e., the mating ... only the latter is regarded. Like in the pheromone pathway, a receptor activates a G protein, which is competent to initiate a MAP kinase cascade viaSte20. That cascade consists ofthe MAPKKK ... ina crossac-tivation. Inthe same paper it is demonstrated that the invasive growth pathway can also leak into the matingpathway. However, activation of Fus3 by the filamentousgrowth pathway...
... (we managed to discard89.5% of all the initial candidates automatically)made it easier for us to manually validate the re-maining keywords. This allowed us to incorporatesupervision into the ... downweightingsuch features, maxent is capable of modelling to a certain extent the special characteristics which arisefrom the automatic or weakly supervised trainingdata acquisition procedure. We used the ... equiva-lents that were eliminated due to the noise present in the automatically generated training data.We manually examined all keywords that had a P (spec) > 0.5 given as a standalone instance...
... purposes)Activation of NADPH oxidase inthe presence of glial iNOS is synergistic in killing co-cultured neuronsFigure 2Activation of NADPH oxidase inthe presence of glial iNOS is synergistic in ... sclerosis, meningitis, AIDS dementia, strokes, traumaand normal brain ageing [6,7]. It is therefore important tounderstand the mechanisms by which inflammatory-acti-vated glia kill neurons.Astrocytes ... author(s) declare that they have no competinginterests.Authors' contributionsPM participated inthe design of this study, did the labwork, data analysis and wrote major parts ofthe paper.GCB...
... feasibility of establishing CVCT in ant enatal clinics, we t rained clinic staff at two antena talclinics in Lusaka, Zambia, and two antenatal cl inics in Kigali, Rwanda, to provide same-day rapid ... multivariate analysis fromvariables that were statistically significant in the bivariate analysis or were considered importantin the context ofthe study. Odds ratios and confide nce inter-vals ... women in Kigali. In 2001, 21% of the women in Kigali who came to the antenatal clinics par-ticipating in this study already knew their HIV status,perhaps diminishing the impact of VCT among thispopulation....
... circle, a likelihood ratio is computed for the alter-native hypothesis that there is an increased risk of dis-easeinsidethecircle,againstthenullhypothesisthat the risk inside the circle isthe same ... this article as: Wand and Ramjee: Targeting the hotspots:investigating spatial and demographic variations in HIV infection in small communities in South Africa. Journal ofthe International AIDSSociety ... equally1National Centre in HIV Epidemiology and Clinical Research, Sydney, AustraliaFull list of author information is available at the end ofthe articleWand and Ramjee Journal ofthe International...