identify the main idea of each paragraph in i have a dream
Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"
... A. T. The Wnt 5A/ protein kinase C pathway mediates motility in mela-noma cells via the inhibition of metastasis suppressors and ini-tiation of an epithelial to mesenchymal transition. J Biol ... expression and localization. Indeed, a study shows that increasing β-catenin in- creases the expression of claudin-1 in colorectal cancer cells, and that claudin-1 expression is increased in more aggressive ... metastatic capacity. Key words: Claudin, melanoma, metastasis, PKC, PKA Introduction Claudin-1 is a member the claudin family of proteins, which are important in tight junction forma-tion...
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Computer illiteracy as one of the main problem of business student
... one of main problems of business students.Symptoms The main symptom of the computer illiteracy is an inability in computer working. Forexample, student cannot find necessary information the Internet, ... first alternative. If it doesn’t work there is another way of increasing motivation.We can conclude an agreement with IT department to apply to the diploma certificate forthose who have finished ... will be solved. Alternative 2And what about reaction of principal? If the principal doesn’t agree to realize our firstalternative of solving the problem, what can we suggest? We have another...
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Tài liệu Đề tài " The topological classification of minimal surfaces in R3 " pptx
... was a compressing disk, there is a cycle of Γ contained in the boundary of the singular disk, and it is disjoint from HP i meaning that we have a cycle in a ball and this ball lies outside of ... essential manner in two pointsmust have both their endpoints in the same boundary component of the pair of pants. This implies that such a bad arc is contained inside a bad arc from the original picture.Finally, ... solid Annals of Mathematics The topological classification of minimal surfaces in R3 By Charles Frohman and William H. Meeks III* 684 CHARLES FROHMAN AND WILLIAM H. MEEKS III in the...
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Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... 500Pacific OceanAtlantic OceanIndian OceanAccess to sanitation facilities a a i ccOceOceOceO a ananSouth Eastern AsiaEast AsiaSouth AsiaWest AsiaCommonwealth of Independent StatesLatin ... StatesLatin America and CaribbeanOceaniaNorth AfricaSub-Saharan AfricaType of sanitation facilityMillion peopleSource: JMP, Progress in drinking water and sanitation, 2008.Improved: facilities ... SUMMARY The world is facing a global water quality crisis. Continuing population growth and ur-banisation, rapid industralisation, and expanding and intensifying food production are all putting...
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Tài liệu Báo cáo khoa học: "The Effect of Corpus Size in Combining Supervised and Unsupervised Training for Disambiguation" pdf
... 2006.c2006 Association for Computational Linguistics The Effect of Corpus Size in Combining Supervised andUnsupervised Training for DisambiguationMichaela AttererInstitute for NLPUniversity of Stuttgartatterer@ims.uni-stuttgart.deHinrich ... attachmentdecision in some cases. The actual syntacticdisambiguation is performed by computing the a nity (maximum over MI values in the lat-tice) for each possible attachment and select-ing the attachment ... unsupervised PP attachment. In CICLing.Eugene Charniak. 1997. Statistical parsing with a context-free grammar and word sta tistics. In AAAI/IAAI, pages 598–603.Michael Collins and James Brooks. 1995....
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Tài liệu The high price of pain: the economic impact of persistent pain in Australia pdf
... complex and disabling pain, the training of all health professionals in this work, research into persisting pain, and public education about chronic pain and its management. ã However, most patients ... chronic pain. Although rarely primary causes of chronic pain, psychological and environmental factors often play a critical role in the maintenance of chronic pain and associated disability. The ... the prevalence of chronic pain and its impact on individuals and health services and the broader community. 2.1 DEFINITION AND GRADING1 The International Association for the Study of Pain...
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Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... in increasedamyloid fibril formation. This increase may be due to a direct inhibitory effect of this nine-amino-acid sequence, orto disequilibrium in the hydrophobic-hydrophilic balance of the ... peptide with BB1 indeed resulted in a 35% inhibition of amyloid fibril formation.Our results are in keeping with the clinical observations of Arg124 mutation-linked amyloidosis and show the import-ance ... particularintegrins with binding capacities for the corneal TGFBIprotein remain to be fully identified. Kim et al. [3] have recently shown that alpha3-beta1 integrins bind to TGFBI.Two major sites...
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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc
... increased expression of a3 b1integrin in gastric carcinoma cells is associated with theirincreased invasion and metastatic potentials [24,28]. Thus, the transcriptional regulation for the integrin ... region with the positions for HindIII (H) and EcoRI (E). The restriction map for the 5Â-anking region is also shown at a highermagnication (lower line). The translation initiation site is indicated ... in association with changes in theirinvasive and metastatic potentials [19–27]. In gastric carci-noma, melanoma, and glioma, the expression of the a3 b1integrin in these cells was positively...
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Occupational therapy interventions and physical activity interventions to promote the mental wellbeing of older people in primary care and residential care pdf
... partners in maintaining or improving their quality of life − pay particular attention to communication, physical access, length of session and informality to encourage the exchange of ideas ... social relationships and maintaining friendships ã dining as an activity ã interests and pastimes ã caring for others, caring for self 43 exercise programmes cover a range of types, settings ... and awareness of where to get reliable information and advice on a broad range of topics, by providing information directly, inviting local advisers to give informal talks, or arranging trips...
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Among the Great Masters of Music Scenes in the Lives of Famous Musicians pptx
... us a paraphrase of Raphael's painting of music'spatron saint in his fine picture of Mrs. Billington, the famous English singer of his last years, as St. Cecilia.She holds a music ... to paint a picture for the altar. It was finished in 1516.Tradition relates that Pucci had no ear for music, and was laughed at by his brother cardinals when chantingmass in the Sistine Chapel. ... effective picture of the great violinist in prison is an instance of the use of that license which we aregenerally willing to allow the painter and the poet. Among the many astounding fictions which...
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Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt
... for-mer and a higher level of nuclear accumulation for the latter, indicating that in the absence of an N-terminaldomain distinct localization is lacking. Finally, the Lsm1p Sm domain by itself ... C-terminal domain mutations. (B) Lsm8p N-terminal domain muta-tions and recombinant Lsm1p containing the Lsm8p N-terminal 10 amino acids. (C) Sm domain replacements; see Fig 2A for an explanation ... andhybrid Lsm1 and Lsm8 proteins, shedding light on the relative importance of their various domains in determining their localization and ability tosupport growth. Although no single domain is either...
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WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses docx
... Breakthrough pain is characterized as a temporary increase in the severity of pain over and above the pre-existingbaselinepainlevel,e.g.if a childistakingpainmedicinesandhasgoodpaincontrolwith a stableanalgesicregimenandsuddenlydevelopsacuteexacerbation of pain.Itisusually of suddenonset,severe,and of shortduration. A number of episodes of breakthroughpaincanoccur each day.It ... health-care workers from providing basic pain care (66).Managingpainstartswithrecognizingandassessingpain.Therefore, planning pain assessment as an integral element of pain management at all ... painChildrenexperiencingpaincanbelimited in theirphysicalactivitiesaswellas in theirdevelopmentbecausetheyfacedifculties in concentratingandlearning.Iftheirpainisnotmanagedwell,theirquality of lifecanbeaffected,resulting in impairedphysicalfunctioning,anxiety,fear,stressandsleepdisruption...
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The Carbon and Global Warming Potential Impacts of Organic Farming: Does It Have a Significant Role in an Energy Constrained World? pptx
... significant debates about how to account for regional variability, measurement uncertainties, process uncertainties, identifying real additionality, reducing leakages, and appropriate pricing ... significant variability in the volume and type of studies examining organic vs. conventional systems (see Table 8). Table 8. Relative availability of literature. Sector Literature Availability** ... improvements in efficiency gained at the farm level can be lost through inefficiencies further along the chain, including processing, transport and wholesale/retail. This is particularly important in the...
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