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Báo cáo y học: "Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study" pdf
... pool of T cells [14,15] One of the consequences of dysregulated T-cell homeostasis is the emergence of large clonal CD4+CD28null T-cell populations that are autoreactive and cytotoxic, and infiltrate ... history of CAD diagnosis and intervention prior to evaluation at Mayo The control population consisted of 130 individuals with CAD but no history of RA, two of whom were excluded because of a history ... any cause, CABG, MI and PTCR was recorded by review of the medical record Mean duration of follow-up was 62.4 months for the RA and CAD cases and 57.8 months for the CAD-only controls The mean...
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Báo cáo khoa học: "Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients" ppt
... contributions Each author of this manuscript has: made substantial contributions to conception and design, acquisition of data, and the analysis or interpretation of data; been involved in drafting the ... cause one to pause before assuming that our study disproves such a consistently strong association The dangerous and costly considerations of prolonged ICU and hospital stays shown in this cohort ... score, and Charlson for the mortality analysis only Time -to- event curves were created according to the methods of Kaplan and Meier [24], and were compared using log-rank tests All statistical analyses...
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Báo cáo y học: "Intensive care acquired infection is an independent risk factor for hospital mortality: a prospective cohort study" pot
... acquisition and analysis of data, and drafted the manuscript TA-K, JL, and HS participated in the design of the study and the analysis of data and drafted the manuscript PO participated in the ... in the group with no infection on admission (p < 0.001) and 4.1 fold in the group with infection on admission (p < 0.001) Discussion Table Outcome data according to infection status on admission ... response to antimicrobial therapy Data registration and statistical analysis Data were collected daily by one of the authors (PY) and entered into an SPSS database (SPSS Data Entry, version 2.0,...
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Báo cáo y học: "Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury" potx
... Authors’ contributions MME conceived of the study design, analysed and interpretated data, and drafted and revised the article RLL, PVdN, MLM, EH, PD and JD conceived of the design, analysed and interpretated ... data, and drafted and revised the article All authors provided intellectual content of critical importance to this project and gave their final approval of this version to be published Page of 12 ... generalized statement of the AKI Network that the provision of RRT in AKI patients is extremely variable and based primarily on empiricism and local institutional practice and resources [28] The AKI Network,...
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Báo cáo y học: " Endothelial Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study" potx
... critical review of the manuscript for important intellectual content and statistical analysis IM-L contributed to acquisition, analysis and interpretation of data, drafting the manuscript and critical ... contributions MM made substantial contributions to the intellectual content of the paper in acquisition, analysis and interpretation of data, drafting of the manuscript, critical review of the ... review of the manuscript for important intellectual content and statistical analysis TL contributed with conception and design, analysis and interpretation of data, drafting of the manuscript, critical...
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Báo cáo y học: "Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation" ppsx
... function [11] To date, there are no data on the expression pattern of TF and TM in any of these monocyte subpopulations This study was the first to demonstrate the phenotypic changes of TF and ... of TF and TM expressions within vessels [5] The existence of different populations of monocytes (CMs, IMs, and DMs) is well established, and each population has a distinct antigen phenotype and ... expressions of DMs were higher than those of the IMs, but the mean differences of the TM and TF expressions of DMs between survivors and non-survivor were not significant and the phenotype of DMs...
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Báo cáo khoa học: Fowlicidin-3 is an a-helical cationic host defense peptide with potent antibacterial and lipopolysaccharideneutralizing activities ppt
... binding and neutralization of lipopolysaccharide (LPS), chemotaxis of immune cells, regulation of dendritic cell differentiation, induction of angiogenesis and re-epithelialization, and modulation of ... factors that influence the antibacterial and toxicity of a-helical cationic peptides [23,24], rational changes of these structural and physicochemical parameters are likely to further improve the ... residues 16 and 19, due to the presence of a glycine at position 17 This was indicated by the fact that the CaH chemical index showed no shift for G17 and I18 (Fig 2), consistent with the notion that...
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Báo cáo y học: "ISsaga is an ensemble of web-based methods for high throughput identification and semiautomatic annotation of insertion sequences in prokaryotic genomes" pdf
... genes and new potential compound transposons, is important Their inclusion gives a significantly more accurate interpretation of the spread and distribution of ISs and provides information about the ... IS Validation Report Nucleotide annotation * No Manual Validation? Stored IS Validation report Validation ISbrowser is the online tool for global IS visualization Figure Flow diagram of the ISsaga ... contributions AMV conceived and developed ISsaga, and drafted the manuscript PS carried out ISsaga tests and design, managed the ISfinder database and drafted the manuscript EG carried out ISsaga...
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The Economic Impact of Cloud Computing on Business Creation, Employment and Output in Europe pdf
... market conditions, that tend to affect the ability of the economy to react to a positive change through job creation, and in the regulatory framework and in the competitive conditions of the goods ... impact on business creation for a simple reason One of the main advantages of cloud computing is an induced change in the market structure of many sectors, with the creation of more firms and an ... decide on the investment in hardware and software and on the allocation of labor and ICT capital to minimize costs, and on the production choices We assume that the stock of both ICT components...
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Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... summarizing the major biosynthetic forms of RNF13 and their relationship to membranes, based on the observed molecular mass and presence or absence of the epitope tags, is presented in Fig 7C The three ... and cell fractionation The validity of the fractionation protocol utilized has been questioned [1], however, and the tmpred algorithm predicts that RNF13 has a TM sequence Consistent with this, ... functions independent of the fulllength, endosomally localized protein There is increasing precedent for proteolysis as a means of mobilizing dormant transcription factors [60] On the basis of their...
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Tài liệu Clerambault The Story Of An Independent Spirit During The War doc
... everything, and it is an injustice to limit him to one place on the earth To the wise man the whole world is his country God lends us the world to enjoy in common on one condition only, that we act ... incapable of understanding the complexities of the people, force thoughts and acts upon them in harmony with their own passions and interests by means of the falsehoods of the press and the implacable ... mind, on a book Maxime went out on the porch and smoked, leaning on the railing and looking down on the sleeping garden and the fairy-like play of the light and shadows on the path The telephone...
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Báo cáo Y học: Ferritin from the spleen of the Antarctic teleost Trematomus bernacchii is an M-type homopolymer doc
... study of cold-inducible gene expression of rainbow trout cells (Salmo gairdneri) revealed that the transcription and accumulation of the mRNA corresponding to three ferritin H isoforms H1, H2 and ... D60 and E64 correspond to sites of iron nucleation in L chains This characteristic, first described for the polypeptide chains of bullfrog ferritin [9], is common to fish ferritins on the basis of ... the structural and functional properties of a homopolymer constructed from an unusual subunit, the M chain, which is capable of carrying out both the iron-oxidation and the iron-mineralization...
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Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
... previously on depletion of human LIN9 and B-MYB [9–11] This suggests that the ability to promote cell cycle progression and mitotic entry is not an isolated function of LIN9 and B-MYB, but that it is ... unequivocally that p130 bound to full-length LIN54 and to the DN, DCXC and HCH mutants, all of which contained an intact HCH region (Fig 3C) In contrast, mutants that lacked the HCH region (DHCH and CXC) ... found that a region of LIN54 that is predicted to form an HCH secondary structure is required and sufficient for binding to p130 and B-MYB Because the corresponding region of tombola, a testis-specific...
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Báo cáo Y học: The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains pptx
... domain automatically folds into the secondary structure of the native toxin On the other hand, the spectra of the T2 and T2¢ fragments exhibit more disordered structures than that of D4 These data ... suggest that the toxin fragments may change the conformation of their cholesterol-binding site to that of the full-size toxin, when they bind to membrane cholesterol We also analyzed their secondary ... manner to those of h-toxin and W137F Compared to W137F and MCh, the maximal emission wavelengths of the T2, T2¢ and D4 fragments are distinctly longer (336–338 vs 345–346 nm) in the absence of...
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Đề tài " The Poincar´e inequality is an open ended condition " docx
... invariant under a translation in the range of u and f Furthermore, the construction of f from u is also invariant under a translation in the range of u and f By this we mean that if u is replaced ... k These bounds are required for the proof to work, and depend only on C and α To realize the contradiction at the end of the proof and thereby prove Proposition 3.1.1, we take k1 to be equal to ... 1.0.1 we mean that ε and the constants associated with the (1, q)-Poincar´ inequality depend only on the constant p, the doubling e constant of μ, and the constants associated with the assumed...
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Báo cáo khoa học: A new highly toxic protein isolated from the death cap Amanita phalloides is an L-amino acid oxidase pdf
... (Edman degradation analysis; Fig 2) (B) Partial nucleotide sequence and deduced amino acid sequence of the toxophallin The amino acid translation is under the second nucleotide of the corresponding ... comparing the in silico tryptic digest of the translated amino acid sequence with the list of masses of tryptic peptides obtained by the MALDI-TOF analysis In total, nine peptides from the list of toxophallin ... Ascorbic acid and reduced glutathione inhibit L-amine oxidase activity of the toxophallin in vitro The reaction mixture consisted of 0.15 mL of 0.1% aqueous solution of toxophallin and 2.5 mL of 0.3...
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Báo cáo khoa học: Completing the hypusine pathway in Plasmodium Deoxyhypusine hydroxylase is an E-Z type HEAT repeat protein docx
... [1] Completion of the parasitic life-cycle requires rapid changes in its environment such as the stimulation and inhibition of cell division An important issue facing global health is the need for ... of PCB to CpcA in the presence (——) and absence (- - -) of DOHH (B) Control in the additional presence of the lyase, CpcE ⁄ F (C) Assay for the attachment of PCB to PecA and isomerization to PVB ... covalently to their apoproteins, which then organize into phycobilisomes, the light-harvesting supercomplexes of cyanobacteria and red algae Attachment of the apoproteins to the bilin chromophores is only...
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Báo cáo khoa học: Collective behavior in gene regulation: The cell is an oscillator, the cell cycle a developmental process doc
... measure of the information content of the system as expressed in the vectors and it is clear that in all three experiments the system is globally oscillatory The disadvantage of SVD analysis is the ... system to extract the information content and present it a set of vectors of reduced dimensionality All of these methods lead one to conclude that the cell is an oscillator For those few constituents ... organized and oscillatory In addition, transcripts for mitochondrial and cytosolic ribosomal proteins, sulfur metabolism, amino acid biosynthesis and most of the Golgi and peroxisome-related transcripts...
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a tear is an intellectual thing the meanings of emotion feb 2000
... constitute part of the identity of an emotion The connection of emotion and expression is more than contingent, but only loosely necessary The connection is defeasible when there is an explanation ... trying to answer the question There are a number of recurring themes Among them are the relation of the normal and the pathological, the relation of individual development and cultural history, the ... excites the mental affection called the emotion, and that this latter state of mind gives rise to the bodily expression My thesis on the contrary is that the bodily changes follow directly the perception...
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REQUEST FOR PROPOSALS FOR AN INDEPENDENT FINANCIAL AUDIT OF THE NASSAU COUNTY INTERIM FINANCE AUTHORITY_part1 pptx
... VI Administrative Information and Conditions VII Other Conditions and Limitations VIII Disclosure of Proposal Contents/State Finance Law Appendix I Non-Collusive ... for Standard Annual Audit Services, which contains all pricing and staffing information relative to fulfilling the scope of services described in Section III A of this RFP Proposal One: o The ... estimates and project management and supervision structure A statement to the effect that the price quoted is an irrevocable offer for 120 days from the date of submission B Cost Proposers must...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25