how modern genomics informs basic clinical and translational science
Tài liệu ACCELERATING PROGRESS AGAINST CANCER: ASCO’s Blueprint for Transforming Clinical and Translational Cancer Research doc
... Transforming Clinical and Translational Research 23 Develop industry standards for working with biospecimens: ASCO will work with NCI and with colleagues in clinical research, pathology and epidemiology ... nation’s translational and clinical research system is unprepared to deliver on this promise This report from the American Society of Clinical Oncology lays out a vision for an approach to clinical and ... cells and the cell’s surrounding environment Clinical trials will be launched and completed far more quickly Every patient will have the opportunity to contribute to translational and clinical...
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modern fluid dynamics basic theory and selected applications in macro- and micro-fluidics
... traditional and modern fluid dynamics, i.e., the fundamentals of and basic applications in fluid mechanics and convection heat transfer with brief excursions into fluid-particle dynamics and solid ... Kleinstreuer, Modern Fluid Dynamics: Basic Theory and Selected Applications in Macro- and Micro-Fluidics, Fluid Mechanics and Its Applications 87, DOI 10.1007/978-1-4020-8670-0_1, © Springer Science+ Business ... Definitions and Concepts A sound understanding of the physics of fluid flow with mass and heat transfer, i.e., transport phenomena, as well as statics/dynamics, stress–strain theory and a mastery of basic...
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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... involved in transcriptional and translational processes As shown in Table 1, the up-regulated genes were COBRA1, ITGB4, STAU2, and HMGN3 with a SLR of 3.30, 2.61, 1.68 and 1.52, respectively ANK3 ... factors (AP1, Elk1, Stat1, SRF and NFκB) and expression of apoptotic genes (Fas receptor, Fas ligand, FADD and caspase 8) [19] In addition, as confirmed by the functional genomics analysis presented ... (n=6) Each single array had good quality control and showed a normal distribution and linearity The red zones indicate up-regulated gene expression and the green zones indicate down-regulated gene...
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Tài liệu Measuring Immunity: Basic Biology and Clinical Assessment doc
... Enumeration and Phenotyping 231 19 Handling and storage of cells and sera: practical considerations Stephen E Winikoff, Herbert J Zeh, Richard DeMarco and Michael T Lotze 233 20 Phenotypic and functional ... basic science foundations as well as the approaches currently applied and found valuable in the disparate and inchoate regions of clinical medicine As always the ‘conjurations, inchantments and ... When and how this panoply of countermeasures is deployed is specific to each pathogen However, it is this constant struggle between man and pathogen and between protective controlled response and...
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Measuring Immunity: Basic Biology and Clinical Assessment pot
... Enumeration and Phenotyping 231 19 Handling and storage of cells and sera: practical considerations Stephen E Winikoff, Herbert J Zeh, Richard DeMarco and Michael T Lotze 233 20 Phenotypic and functional ... basic science foundations as well as the approaches currently applied and found valuable in the disparate and inchoate regions of clinical medicine As always the ‘conjurations, inchantments and ... When and how this panoply of countermeasures is deployed is specific to each pathogen However, it is this constant struggle between man and pathogen and between protective controlled response and...
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ORTHODONTICS – BASIC ASPECTS AND CLINICAL CONSIDERATIONS ppt
... of the IOTN Mandall et al (2000) and Birkeland et al (1996) concluded that it is a reproducible and reliable index A recent study by Johansson and Follin (2009) showed that the clinical criterion ... year) Brook and Shaw (1989) So and Tang (1993) So and Tang (1993) Burden and Holmes (1994) Tuominen et al (1995) Tang and So (1995) Birkeland et al (1996) Otuyemi et al (1997) Riedmann and Berg ... many indices and measures for assessing malocclusion, but the DAI and the IOTN are the best known and most widely used owing to their manageability and proven validity Tables and show a number...
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AGE RELATED MACULAR DEGENERATION – THE RECENT ADVANCES IN BASIC RESEARCH AND CLINICAL CARE potx
... Dreyfuss and H B Nader 73 83 Basic Research and Clinical Application of Drug Delivery Systems for the Treatment of Age-Related Macular Degeneration 99 Giuseppe Lo Giudice and Alessandro Galan Clinical ... Macular Degeneration – The Recent Advances in Basic Research and Clinical Care presents the most recent advances in basic research and clinical care of AMD. Different from other ... to cover the new findings from basic and translational research on the biological and genetic mechanism of AMD, and the new interventions to prevent and treat this disease. The book has a total of 15 chapters, grouped into two sections. Section one includes six ...
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Báo cáo y học: "How to integrate individual patient values and preferences in clinical practice guidelines? A research protocol" pps
... making? For example: How should clinical practice guidelines and patient decision support technology be linked, and what are barriers and facilitators for doing so? What types of clinical decisions ... based on clinical practice guidelines Our research questions are: How should clinical practice guidelines be adapted to elicit individual patients’ preferences and to support patients’ and health ... appraisal of an individual who is informed and knowledgeable about the probabilities and severity of the effects and risks of interventions, and about process and outcome aspects of healthcare For...
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báo cáo khoa học: "Genome Medicine: stem cells, genomics and translational research" pptx
... solid foundation for clinical translation and lead to those unexpected Page of discoveries that drive future innovation We hope that this series on translational stem cell genomics provides a ... interconversion should drive bioengineering and fuel the next advances in the creation of artificial organs And finally, with an increased ability to manipulate and generate stem cells of various tissues ... 126:663-676 doi:10.1186/gm250 Cite this article as: Orkin SH: Genome Medicine: stem cells, genomics and translational research Genome Medicine 2011, 3:35 ...
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báo cáo khoa học: " How to integrate individual patient values and preferences in clinical practice guidelines? A research protocol" pptx
... making? For example: How should clinical practice guidelines and patient decision support technology be linked, and what are barriers and facilitators for doing so? What types of clinical decisions ... based on clinical practice guidelines Our research questions are: How should clinical practice guidelines be adapted to elicit individual patients’ preferences and to support patients’ and health ... appraisal of an individual who is informed and knowledgeable about the probabilities and severity of the effects and risks of interventions, and about process and outcome aspects of healthcare For...
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Báo cáo y học: " HIV research in Australia: linking basic research findings with clinical and public health outcomes" ppsx
... generated important basic science findings that have arisen from astute clinical observations and detailed study of clinical samples The initial description of the association between clinical resistance ... strategies Beyond the basic and clinical sciences, Australian researchers have also been active in epidemiological and social research related to HIV infection The effectiveness of needle and syringe programmes ... double stranded (ds)RNA activated PKR system and its role in restricting HIV replication in astrocytes [23]; and critical steps in HIV RNA and reverse transcriptase dimerisation, packaging and virion...
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Modern bayesian modeling to solve common but complex clinical and epidemiological problems in ophthalmology
... patience and guidance in scientific writing and my colleagues and friends, Tay Wan Ting, Maisie Ho, Haslina Hamzah, Ong Peng Guan, Huang Huiqi and the SEED team for their friendship and encouragement ... Framework and Literature reviews 1.1 INTRODUCTION Uncertainty plays a very important role in clinical medicine and research as the translation of scientific discoveries and clinical ... implementations and remains acceptable in practice, there is increasing trend of computational intensive needs to handle large and increasing complexity of datasets Ongoing developments of new and modern...
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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... endoscopic and radiographic Asymptomatic colonic and gastric carcinoma may present with IDA and exclusion of these conditions is of prime concern The upper endoscopic evaluation should include random ... diagnostic yield of endoscopy in patients with IDA and to define predictive factors of gastrointestinal (GI) lesions causing IDA and identify clinical and biochemical variables that predict the outcome ... criteria and were enrolled Their mean age was 43.3 (19-81) years 71 were patient aged under 50 and 20 were over 50 years 77 were female and 14 were male Sixty-six of women were pre-menopausal and...
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How does ppp hold between australia and its trading partners.pdf
... Enders (1988) and Ardeni and Lubian (1991) reject long-run PPP However, Diebold, Husted and Rush (1991), Cheung and Lai (1993), Edison (1987), Frenkel (1981), Branson (1981), Desai (1981), and Miller ... trade barriers Australia has joined WTO and signed free trade agreements with the United States and Thailand in 2005, with Singapore in 2003 and with New Zealand from 1993 It is now in negotiating ... countries and areas such as Japan, ASEAN, Malaysia, China, Chile and Gulf countries This research project tests the PPP between Australia and its trading partners over the period from 1984 to 2006 and...
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HOW DOES PPP HOLD BETWEEN AUSTRALIA AND ITS TRADING
... Enders (1988) and Ardeni and Lubian (1991) reject long-run PPP However, Diebold, Husted and Rush (1991), Cheung and Lai (1993), Edison (1987), Frenkel (1981), Branson (1981), Desai (1981), and Miller ... trade barriers Australia has joined WTO and signed free trade agreements with the United States and Thailand in 2005, with Singapore in 2003 and with New Zealand from 1993 It is now in negotiating ... countries and areas such as Japan, ASEAN, Malaysia, China, Chile and Gulf countries This research project tests the PPP between Australia and its trading partners over the period from 1984 to 2006 and...
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How Our Actions Create our reality ... and how we can change it
... surge and collapse in demand occurred in the semiconductor industry in 1973 to 1975 After a huge order buildup and increases in delivery delays throughout the industry, demand collapsed and you ... managing through the dramatic changes and unpredictability of the world oil business in the 1970s and 1980s came in large measure from learning how to surface and challenge manager's mental models ... disciplines in that they are "personal" disciplines Each has to with how we think, what we truly want, and how we interact and learn with one another In this sense, they are more like artistic...
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VoIP: How to Plan for the Bandwidth and Calculate the Cost Savings
... CFOs, CIOs and others involved on the cost side of any business This white paper will show the cost justification for voice and data network integration and how much increase in bandwidth will ... line as shown above Therefore, 10 lines require 104 Kbps extra bandwidth in the busiest hour at HQ and six lines at each remote site require 62.4 Kbps extra bandwidth Bandwidth at HQ and the remote ... courses and enhanced, hands-on labs offer practical skills and tips that you can immediately put to use Our expert instructors draw upon their experiences to help you understand key concepts and how...
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Principles from How to WiHow to Win Friends and Influence People
... feel important – and it sincerely Win People to Your Way of Thinking Show respect for the other person’s opinion Never say, “you’re wrong” If you’re wrong, admit it quickly and emphatically Begin ... sympathetic with the other person’s ideas and desires Appeal to the nobler motives Dramatize your ideas Throw down a challenge Be a Leader Begin with praise and honest appreciation Call attention ... seem easy to correct Make the other person happy about doing the thing you suggest Hope you enjoy and find it useful for you! Dale Carnegie ...
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