... II celldeath – autophagic celldeath 16 1.2.3 Type III celldeath – necrosis 21 1.3 Programmedcelldeath (PCD) in protozoan parasites .23 1.3.1 Occurrence of PCD in unicellular ... postulates and to fill the gap of our understanding in the pathogenesis of Blastocystis 1.2 TypesofcelldeathCelldeath is a fundamental biological process Programmedcelldeath (PCD) is generally ... of PCD in unicellular eukaryotes The existence of PCD in unicellular organisms may seem counterintuitive, as each cellcan survive as an individual and the deathof the cell means the death of...
... photophase of individual days Glucose oxidase prevents programmedcelldeath expressed with a PCD score of 0–6, where a score of indicates no change, and a score of signifies completion of PCD with ... action of an insect steroid hormone in steroid-induced programmedcelldeath Mol Cell Endocrinol 263, 18–28 Kakei M, Iwami M & Sakurai S (2005) Death commitment in the anterior silk gland of the ... 20E shows that they acquire the responsiveness to 20E days before the onset of spinning, and their responsiveness is covered by GOD in the ASG inner cavity This may be a typical example of a behavior...
... Reinbothe et al JA and celldeath Fig Central role of JA in celldeath regulation in plants Animals respond to many external factors with a plethora of different celldeath pathways of which two are ... JA-mediated celldeath in irradiated flu plants is likely to be a form ofprogrammedcelldeath (PCD) [29] In many aspects it resembles PCD and apoptosis in animals [95–99] This includes cell condensation, ... Plant programmedcell death: a common way to die Plant Physiol Biochem 38, 647–655 96 Hoeberichts FA & Woltering EJ (2002) Multiple mediators of plant programmedcell death: interplay of conserved...
... viability might be a specific feature of ADF cells, we tested the effect of ANT1 siRNA on the viability of an additional glioblastoma cell line, the U87-MG cells U-87-MG showed a higher number of ANT1 ... effect on cell viability might be a result of the onset of a programmedcelldeath process, we analyzed the effect of siRNA in the presence of the protein synthesis inhibitor puromycin As shown in ... Scramble-transfected cells, as well as in nontransfected control cells As shown in Fig 3, ANT1 siRNA-transfected cells show a slightly reduced number of mitosis and a significantly increased number of apoptotic...
... subsides, a minor subset of T cells down-regulate PD-1 and become memory cells, while the larger pool of effector cells extinguishes through a range of mechanisms leading to cellular apoptosis Conversely, ... robust expansion of epitope-specific CD8+ T cells (on the order of 1/2 - 1/10 specific T cells/total CD8+ T cells), reversing the order of the vectors resulted in a limited overall T cell expansion ... levels of PD-1 expression on specific CD8+ T cells The induction of T cells with a high PD-1 expression level by peptide immunization alone may be due to co-presentation by professional and non-professional...
... the cells were left completely untreated The percentage of viable cells is shown in the lower right quadrants of the dot plots (C) Bar graphs showing the fraction of viable cells for each of the ... exclusively of PIpositive cells did not account for a significant fraction of highly disintegrated dead cells that - due to diffusion of the dye - had already become PI-negative again (shown e g ... certain typesof ciPCD, as intracellular calcium influx caused by ER stress induces activation of calpains, a family of calcium-dependent cytosolic proteases that can elicit ciPCD [2] Members of the...
... the pathogenesis of a variety of diseases [21] A number of pathogens cause host celldeath with features of apoptosis [22-24] Pyroptosis is a recently described type ofcell death, in which caspase ... considered to be P < 0.05 Results Intracellular growth and cytotoxicity of L pneumophila in A549 cells First, we verified the infection and intracellular growth of L pneumophila in A549 cells Intracellular ... 2006, 372:173-178 Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification ofprogrammedcelldeath in situ via specific labeling of nuclear DNA fragmentation J Cell Biol 1992, 119:493-501 Anderson P:...
... effect of hypoxia on the expression levels of HO-1 and HO-2 in various typesof human cell line, including erythroleukemia and hepatoma cells We have shown that hypoxia reduces the expression of ... expression of the a-globin gene in K562 human erythroleukemia cells [33] and the number of hemoglobin-producing cells in YN-1 cells [27,34] Conversely, the deficiency of heme in erythroid cells causes ... two human cancer cell lines, HeLa cervical cancer and HepG2 hepatoma cells Hypoxia (1% oxygen) decreased the expression levels of HO-1 and HO-2 mRNA after 48 h of incubation in the two cell lines...
... particular form ofcell death, much less the operational concept ofprogrammedcell death, canbe attributed exclusively to either developing or mature cells Conversely, it has been argued that ... understanding both of cellular and molecular mechanisms ofcell demise, as well as of mechanisms of degenerative diseases, the confusion between apoptosis and programmedcelldeath has somewhat ... understanding of nonapoptotic forms ofprogrammedcelldeath may have been unnecessarily delayed Indeed, well before the upsurge in the understanding of mechanisms of apoptosis, a clear warning had been...
... expression of BIM, 6058 the induction of apoptosis is often modest However, two studies have now shown that erlotinib or gefitinibinduced celldeathcanbe greatly enhanced by co-administration of ABT-737 ... tumour celldeath However, a recent study suggests that repression of BIM might not be a direct effect of TOR mTOR exists in mammalian cells as two distinct complexes: mTORC1 (composed of mTOR, ... activation Treatment of primary AML cells with either of two FLT3 inhibitors (AG1295 or PKC412) caused a substantial cell- death response [70] Activation of the PI3K–PKB pathway downstream of FLT3 was...
... blebbing is one of the characteristic hallmarks ofprogrammedcell death, its exact contribution to celldeath remains unclear It has been suggested that vigorous blebbing may help mix intracellular ... activate autophagy, which has recently been shown to be antitumorigenic [38–40] Overexpression of DAPK can significantly induce membrane blebbing in various celltypes [41–43], but relatively little ... identified during reassembly of a contractile actin cortex under the membrane of blebs in filamin-deficient blebbing cells has not been examined in blebs of cells undergoing celldeath Although the proteins...
... that it be + set at 46 m-equiv/ of red cell K populations were found tidns The choice of the cut-off point, according In a previous study of 14 Spanish goat breeds with a high number of LK and ... cattle might be caused by the small number of HK animals found generally in that species We hope to collect a sufficiently large number of animals among the offspring of parents with known cell type ... Red -cell potassium has also been shown to be polymorphic in buffaloes & Ro 1968 ; S 1974) and yaks (K 1977) , y , ENGUPTA , AMENEK ANDEY (P the The purpose of the present paper is to describe...
... premature programmedcelldeath and cytochrome c release Plant Cell 2001, 13:1803-1818 Selga T, Selga M, Pāvila V: Deathof mitochondria during programmedcelldeathof leaf mesophyll cells Cell Biology ... Background Programmedcelldeath in plants Programmedcelldeath (PCD) is the regulated deathof a cell within an organism [1] In plant systems, developmentally regulated PCD is thought to be triggered ... plant PCD The effect of CsA on the mean ratio of number of perforations per cm of leaf length for control and treatment groups The mean ratio of number of perforations per cm of leaf length decreased...
... diseases of the upper aero-digestive tract [15] In the past decade, a number of studies were carried out in order to characterise the mode ofdeathof cells challenged with different doses of cigarette ... percentages of cytotoxicity of the cells treated with the higher doses (3 and puffs) were not significantly different (p < 0.62) FACS analysis of Annexin V/PI-stained cells To determine the mode ofcell ... cigarette smoke through the wall of the capillary vessels on the surface of alveoli T cells are one of the major groups of immune cells activated and recruited at the sites of lung lesions caused by...
... stem cells reside in a specific area of each tissue called a “stem cell niche” Adult stem cells Embryonic stem cells can become all celltypesof the body because they are pluripotent • canbe ... cells Stem cell potency Stem cell properties Different typesof stem cell Embryonic stem cells Presenter: Bach Thi Hoai Phuong Different kinds of stem cells • Embryonic stem cells (ES): the cells ... characteristic of induced pluripotent stem cells • Induced pluripotent stem cells or IPSCs are a type of pluripotent stem cells that canbe generated directly from adult cells • IPSCs canbe able seft-renewing...
... liegt bei Mọnnern bei 72 Jahren und bei Frauen bei 74 Jahren (Robert Koch Institut (RKI) und Gesellschaft fỹr epidemiologische Krebsregister in Deutschland e.V (GEKID), 2010) Die 5-Jahres-ĩberlebensrate ... drastisch bei vorliegen einer Metastasierung Ein Patient mit Fernmetastasen hat eine mittlere ĩberlebenszeit von weniger als 12 Monaten (Rỹbben et al., 2007), wọhrend die 5-Jahres-ĩberlebensrate bei ... American Type Culture Collection (ATCC), Wesel, Deutschland (Zelllinien stammen aus humanen Urothelkarzinomen) 3.1.9 Software Microsoft Office Word 2007 Fa Microsoft, Redmond, USA Microsoft Office...
... release of intracellular contents In contrast, inflammation is not typical of apoptosis, because phagocytic cells rapidly engulf apoptotic cells and thereby prevent the release of noxious intracellular ... 17:286292 Vandenabeele P, Declercq W, Berghe TV: Necrotic celldeath and ‘necrostatins’: now we can control cellular explosion Trends Biochem Sci 2008, 33:352-355 Page of (page number not for citation ... elimination of key effector cells and, alternatively, the capacity of apoptotic cells to induce anergy and a shift to a Th2 -cell response Furthermore, apoptosis of gastrointestinal epithelial cells...
... The use of metaphor in poetry is one of the most important aspects of poetic style that must be mastered Metaphor canbe described as figure of speech in which a thing is referred to as being something ... analysis procedure 4.1 Results A summary oftypesof metaphor used in our data is shown in the table blow: Table Typesof metaphor in Shakespeare’ sonnets Typesof metaphor Sonnets 2i 10 11 12 5i /5ii ... into the role of metaphor in description of emotion in poetic discourse situation of a text has been described by Halliday (Halliday and Hasan 1985: 12) in terms of the variables of Field, Tenor...