... monosaccharide in the lumen of the intestine is sensed by a sugar sensor, which is located on the lumenal surface of theintestinal epithelial cell membrane, and is distinct from SGLT1 To delineate the signal-transduction ... according to the BioRad assay technique Bovine c-globulin was used as the standard [18] The plasma membrane origin of the BBMVs was assessed by determination of the enrichment of the activity and the ... investigations on the stereoselectivity of the glucose sensor [4,12], we chose the ether linkage to O6 of glucose; being a primary alcohol, the 6-OH is the most reactive once the anomeric position...
... this hypothesis [31] One of the protective mechanisms of the gut mucosa is the constant renewal and shedding of epithelial cells at the top of the villi in the small bowel and from the colon ... others aspect of pathogenesis Amongst them are the alteration of theintestinal epithelial tight-junctions, the effacement of the brush border microvilli, mitochondrial-dependant apoptosis, the ... important factor in the host defense Theintestinal immune system faces the constant challenge of discriminating between the commensal microbiota and pathogens The response to the latter is usually...
... neither endotoxin nor dopexamine had any influence on FCD in intestinal mucosa At first glance, the unchanged FCD in theintestinal mucosa appears to be contradictory to the changes in IMBF in the ... leucocyte adherence on submucosal venular endothelium by IVM of the small bowel wall; they also underwent evaluation of FCD in theintestinal mucosa and the circular as well as longitudinal muscle ... of the gut Pilot experiments have demonstrated that low dosages of enbucrilate not influence intestinal blood flow or intestinal function The position of the probe was not altered during the...
... [25-27] However, the extent of the impairment of the functional density depends on several factors (for example, the serotype, the dosage, and the endotoxin activity of the LPS used for the induction ... Blood samples for the laboratory analyses were drawn 30 and 120 minutes after the start of the experiments At the end of the IVM experiments, animals were sacrificed, and samples of intestinal tissue ... 30 to 40 μm) The same procedure was done by focusing random fields of the capillaries within the longitudinal as well as the circular muscle layer and the mucosa Evaluation of all the video sequences...
... cells in theintestinal crypt 51 3.3.2 Epithelial cells in theintestinal crypt move vertically upwards towards the top of the crypt 53 iv 3.3.3 Movement of epithelial ... throughout theintestinal crypt The models also suggest that with differential adhesion, cells migrate more rapidly as they approach the vii top of theintestinal crypt By calculating the spatial ... Organisation of thesis In Chapter 1, the important biological knowledge used in this thesis is explained In particular, the cell adhesion properties, theintestinal epithelium that is used as the biological...
... the toxicity and in the effects on inflammatory-immune processes of cigarette smoke There are many ROS inducers among these toxic components, and they cause the oxidative stress resulting in the ... added to the cultures with or without stimulants, and the extent of cell death was assessed by measuring the activity of LDH released from the dead cells The level of LDH activity in the culture ... Thus, the MMP-related cascade could be involved in the process of CSE-evoked apoptosis in L2 cells Therefore, the MMP activity in these cells treated with CSE (0.25%) was examined with the fluorometric...
... expressed in the apical membranes of intestinal (PEPT1) and renal (PEPT1 or PEPT2) epithelial cells Absorption of intact di- and tri-peptides and related mimetics at theintestinal epithelium or their ... epithelium or their reabsorption at the renal epithelium requires both their uptake from the luminal compartment into the cells and their transport (efflux) across the basolateral membranes to Alafosfalin ... pH 6.0 at the apical (1.5 mL) and 7.5 at the basolateral side (2.6 mL) [20] After washing the inserts with buffer, the TranswellÒ chambers were preincubated for 10 and the transepithelial electrical...
... organs there were only two significant associations for those perch sampled at the reference site (Table 2) The lead content in theintestinal wall of perch increased with the weight of the fish The ... significantly lower in the muscle of perch than in the other fish tissues and in the acanthocephalans at each of the sample sites The highest tissue metal burdens were in the liver with mean values ... small stream entering the lake The reference site was about 10 km away from the motorway on the opposite shore of the lake The fish and mussels were transported alive to the laboratory, weighed...
... During the early scanning period, the B-mode was used for locating the optimal bowel loop, and then the mode was switched to the pulsed Doppler mode The sample volume cursor was located in the small ... were selected The gain setting was grade 78(62~100) and the depth was fixed at level 4, and the other variables were not changed during the scan The time gain compensation followed the usual clinical ... reports on the use of emphasizing the ultrasound for evaluating the gastrointestinal disorders are available [22, 25, 31] The detailed advantages of pulsed Doppler ultrasound over the other methods...
... to have contributed to the lack of change in the region of the present study In conclusion, the present results indicate that the prevalence of G intestinalis and other intestinal parasites in ... studies Therefore, the concept of a high detective factor complex was accepted for the evaluation of the results in the present study The high detective factor complex for each parasite in the present ... Prevalence of Giardia and other zoonotic intestinal parasites in dogs 307 Discussion Until the present study was performed, the authors believed that the recent regional prevalence of intestinal parasites...
... sample, where Ct is the mean of threshold cycle (at which the amplification of the PCR product is initially detected) ∆Ct was the difference in the Ct values for the target gene and the reference gene, ... associated with these events include a reduction in the activity of the transcription factor NFκB and a change in the activity of AP-1 Our results highlight the possibility of the therapeutic application ... differentiation and activation To study the local expression of these factors we performed quantitative RT-PCR of the enzymes involved in the synthesis of these mediators (cyclooxygenase-2 (COX-2)...
... endocrine therapy In Case 2, there was a decrease in the time lag between each endocrine therapy prior to starting fulvestrant However, as noted, the patient responded well to treatment, obviating the ... to initiating therapy In the presence of gastric metastasis, it is found that endocrine therapy (tamoxifen as a first line agent) is used as often as chemotherapy [7] The chemotherapy schemes ... post-operative radiotherapy She then developed recurrences in her lymph node which progressed to her lungs and bones over the years CT scan revealed thickening in the duodenum and in both the ascending...
... associated complications of the disease demand alternative therapeutic strategies There is a lack of research into the role of theintestinal microbiota in CD [9] despite the fact gliadin peptides ... architecture The children included in the study were not treated with antibiotics for at least one month before the sampling time The study was conducted in accordance with the ethical rules of the Helsinki ... PBMCs indicates their maturation level and may predict the quality of interaction between antigen-presenting cells and T cells and thereby their activation Fig shows the results of the analysis...
... knockout C3H/HeJ mice was prepared according to the above protocols These mice were anesthetized with ether and then sacrificed on the rd and 7th day after the administration of TNBS and DSS, respectively ... formed during the incubation was assessed by adding 1.5% thiobarbituric acid and then heating at 95°C for 45 After cooling, the samples were centrifuged, and the absorbance of TBARS in the supernatant ... centrifugation, the supernatant was used for the immunoblot assay The total protein from the collected cells was subjected to electrophoresis on an 8-10% sodium dodecyl sulfate-polyacrylamide gel, and then...
... of the urinary bladder, which was not recognized immediately after the TURP The greater omentun, in a bid to seal off the perforation on the dome of the bladder, entangled the intestine with the ... and multiple adhesions involving the dome of the bladder, the small intestine and the large omentum Adhesiolysis was done and theintestinal loops were released The post- Figure Supine shows distended ... by the Editor-in-Chief of this journal Acknowledgements The authors appreciates the participations of the Doctors in the two surgical units who participated in the management of this patient, thereby...
... adherence to the endothelium in theintestinal submucosal venules To the best of our knowledge, these findings have not been reported for theintestinal wall, which is one of the key sites for the manifestation ... and in the mesentery, but they did not investigate theintestinal wall With respect to the role of theintestinal microcirculation in sepsis [14], the aim of our study was to evaluate the effects ... in submucosal venules of theintestinal wall as a step in the inflammation cascade • The anti-inflammatory properties and the beneficial effect of APC on the impaired intestinal microcirculation...
... catheter insertion, and previous surgery on the oesophagus, stomach or duodenum The study was approved by the Human Ethics Committee of the Royal Adelaide Hospital and performed according to the ... [18] Given the above considerations it was appropriate to initially determine whether GLP-1 attenuates the glycaemic response to small intestinal, rather than intra-gastric, nutrient Whether GLP-1 ... critically ill patients has hitherto not been evaluated The primary aim of this study was to determine whether exogenous GLP-1 attenuates the glycaemic response to small intestinal nutrient infusion...
... Bọ xít hút máu Bọ xít hút máu Không loài vật hút máu, theo nghiên cứu tiến hành giới, loại bọ xít chuyên hút máu sau công nạn nhân khiến cho nạn nhân ... đau nhức dai dẳng, kéo dài nhiều ngày sinh biến chứng khác sốt cao, co giật, hôn mê Muỗi Muỗi - Dracula bé nhỏ Có kích thước cực nhỏ, song muỗi loài vật hút máu giỏi loài hút máu Loài muỗi hút ... chúng khó khiến nạn nhân phát nước bọt chúng tiết có chất gây tê Những muỗi chuyên hút máu xem Dracula có kích thước nhỏ nhất, song đáng sợ việc hút máu, muỗi truyền bệnh sốt xuất huyết, viêm...
... of tissue section The counted areas were selected from random tissue sections, taking into account that the ratio of the area of theintestinal stroma to the area of surface epithelium Page of ... noted in the neighbouring intestinal stroma in cases of either spontaneous or voluntary/therapeutic abortion in comparison to the 8th and 10th gestational weeks The differences among the numbers ... sd = 5.27 ± 0.19) There were very few inflammatory infiltrates in theintestinal stroma expressing the phenotype CD45/LCA and CD3 In cases of voluntary or therapeutic abortion, the frequency of...