... volume index (EI), the relative dose homogeneity index (DHI), the overdose index (ODI), and thedose non-uniformity ratio (DNR), and are defined as: Coverage Index (CI): Thefractionofthe target ... Veenendaal, The Netherlands) – D treatment planning system Thedose points were placed on the surface ofthe target volume relative to the active dwell positions All thedose points, inthe implant, ... the region which receives a doseinthe range of 1.0 to 1.5 times ofthe reference dose, (3) the region which receives a doseinthe range of 1.5 to 2.0 times ofthe reference dose, and (4) the...
... phosphine is a quick and effective tool forthe control of stored-product insect pests In view ofthe scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain ... of all oils tested The main component ofoneofthe oils is pulegone The other is not yet identified and it is called SEM76 (Shaaya and Kostyukovsky, 2006) In our study ofthe mode of action of ... on the rates of sorption of homologous series of ITCs on wheat, we could show that therateof sorption decreases with increasing molecular weight (Shaaya and Desmarchelier, 1995) Inthe case of...
... perfectly and the remaining interference due to crosstalk might increase around the same power level asthe additive noise, thereby decreasing the performance Mathematically, this means that the matrix ... thus on the SNR ofthe corresponding tone forthe different users If we denote by bi the number of bits that could be transmitted on the tone of interest for user i, and by KLMS the number of pilot ... realizations3 ofthe channel as described above It can be seen that the gain is always decreasing for increasing interference coefficients (or decreasing noise variance) It can also be seen that the gain...
... -80oC The extraction of DNA was performed with Fast DNA SPIN Kit for Soil (Qbuiogene, USA) according to the instruction by the manufacturer Inthe preliminary step to nawwor down the species of ... 4oCstored Then, each ofthe samples were divided into two Oneof them was for DNA extraction and was washed with TE buffer at pH8.0, and stored at -20oC Another was for FISH analysis and was stored ... was applied, and the condition was optimized In general, the higher concentration of primers can lead to the formation of primer dimers Also, the cost ofthe chemicals should be minimized if the...
... and, by then delivering the bound metals into the cell, it activates specific protein kinases that induce an increase inthe production of Ab-degrading MMPs Neurotoxicity generated by the interaction ... because of an imbalance inthe activity of tau kinases and phosphatases [3] One particular tau kinase pertinent to metal dyshomeostasis in AD is glycogen synthase kinase-3 (GSK3) GSK3 has recently ... within the physiological ranges that could be expected within the brain The capacity for metals to facilitate this process may therefore be a critical factor inthe Ab mediated pathology of the...
... order, and therate constants were obtained by nonlinear least-squares fitting to the absorbance data The numbering ofthe amino acid residues in each lysozyme protein follows that ofthe Protein Data ... this hypothesis Based on the firstorder rate constants measured inthe model peptide compounds with oligoprolines as spacers and using these results as a ruler forthe proteins, the value of 120 ... signal was observed in all peptides containing tyrosine 23 or 53 but not in peptides containing tyrosine 20 alone According to these results, tyrosines 23 and 53 could be involved inthe dimerizations...
... specified inthe other two studies Vaginal BF was used as a home treatmentin three studies [44,45,47], as home and clinic treatmentinone study [45] and inthe others it was used only at clinic ... What is the evidence forthe effectiveness of physical therapy inthe clinical setting? Only one study stated specifically that the intervention was performed in a physiotherapy clinic in a primary ... care setting may be effective forthetreatmentof SUI The other studies inthe review were considered forthe generalisability of their findings to clinical practice by identifying the patient...
... ascites requiring euthanasia ofthe animals ID8 cells were grown intraperitoneally inC57BL6 mice Twice-weekly intraperitoneal anti-CD52 therapy was initiated one week after the injection of tumor ... detectable inthe presence of heat inactivated Alemtuzumab, 75% of VLC were eliminated inthe presence of fresh Alemtuzumab (Figure 3B(1) and 3C) This was associated with a proportionate increase inthe ... receive no treatment were maintained at 37C inthe ascites fluid throughout the course ofthe experiment Viability of this control aliquot was then assessed with AnnexinV and 7AAD AnnexinV(-)/PI(-)...
... Training protocol and study design Top: Phases ofthe training protocol: Baseline (B1), Robot Training, Baseline (B2), Subject Training, Wash-out The phases in which the robot generates no forces ... compared the primary outcome measures (change inthe clinical scores) between the baseline (T0) and the end ofthetreatment (T3), irrespective ofthe training mode (treatment) As regards the kinematic ... blocks of trials However, no one did, and in fact the task was well tolerated Furthermore, there was no degradation of performance at the end ofthe adaptation phase as compared to the final portion...
... boundary for each class separating it from all the others Including the dynamic portion inthe training set increases substantially the number of windows available for each class, and so the unbalance ... asthe training set Figure 5(b) shows that the SVM-OVO classifier with WT features determines high performance when including the dynamic portions inthe training set An error rateof 6.3% was ... set, training section and classifier The accuracy was evaluated on the testing set on all classes (including the rest class) The classification action was performed if the EMG activity inthe current...
... injury inthe absence of hemoperitoneum on FAST can be ashighas 29% [11] In a recent study, 13% ofthe patients with clinical signs of abdominal injury and a negative FAST for intra-abdominal ... possibility of subsequent bleeding out of vascular injuries that were unnoticed owing to vasospasm [54] and the higher rateof minor complications such as infarctions [52] However, the clinical relevance ... and thehigh mortality rate after operative treatment stimulated the search for alternative treatments, and, in 1990, NOM was introduced as a treatmentfor liver injury [38] Thehigh success rate...
... surface temperature to increase more rapidly increasing the ease of ignition Since the LOI measures ease of extinction, which essentially depends on the same physical phenomena as ignition, the ... with the release of BuOH and excess water After this stage, the pressure ofthe reactor was reduced to less than 100 Pa and maintained for 1.5 h The excess water and BuOH was separated from the ... and 52 mL of BuOH The actual volume of water removed was 184 mL and of BuOH was 50 mL Thus, the extent ofthe reaction was more than 96% Transmission electron microscope images ofthe nanocomposite...
... Total RNA was then isolated using the RNeasy® Micro kit according to the supplier's instructions including a DNase digestion step Following removal ofthe SFB (in the case of co-culture), the shock-frozen ... potent inductors of aggrecanase activity in both cases, underlining the key role of these cytokines in proteoglycan depletion On the other hand, the clearly increased aggrecan activity in co-cultures ... TNF-α/IL-1β), in all cases showing a massively reduced optical contrast ofthe collagen structures in areas near the cartilage surface (Figure 4k1 to k4) Invasion of synovial fibroblasts into the cartilage...
... published guidelines forthe screening and selection of patients for Page of 10 APBI [22,23], and these guidelines formed the basis for patient selection inthe EBT multicenter study [20] Ofthe 65 patients ... breast and skin within an area of less than 2.5 cm ofthe skin surface As seen in Figure 2, this can readily be accomplished by using modifications ofthe standard oncoplastics incisions Since the ... skin bridge will maintain the distance from the balloon to the skin surface The greater the volume ofthe balloon, with the attendant compression of adjacent breast tissue, the more fully the...
... loaded dose was administered forthe first treatment and 80% ofthedosefor subsequent treatments Complete occlusion was achieved in 28% of cases, near in 32%, and partial occlusion was achieved in ... risks include liver failure and gastric irritation caused by seepage into the gastrointestinal tract Until now, the effectiveness of this device forthetreatmentof CRHM has not been examined in ... consisted of vials of DEBIRI loaded with 200 mg of Irinotecan One vial contained beads measuring 300-500 μm and the other contained beads measuring 300-500 μm Zofran was given during the procedure,...
... fractions to the vaginal surface in patients, 5.0 Gy x to the vaginal surface in patient, and 8.0 Gy x to the vaginal surface in patient The mean treatment time was 4.9 minutes Thebrachytherapytreatment ... given the option of treating with an EBT prescription doseof 6.0 Gy x to the vaginal surface or 8.0 Gy x to the vaginal surface Treatment planning was performed according to the standard of care ... followed for months TreatmentThe EBT vaginal brachytherapy was successfully delivered for all 48 treatments inthe 15 patients Inthe 10 patients who received EBT alone, the prescription dose was...
... recording oftreatment planning and treatment data and forthe writing and final approval of this manuscript Competing interests AB was compensated by Xoft, Inc., for his role as Principal Investigator ... Radiotherapy of skin carcinomas ofthe pinna: a study of 115 lesions in 108 patients Int J Dermatol 2005, 44:513-517 Chan S, Dhadda S, Swindell R: Single fraction radiotherapy for small carcinoma ofthe ... The nominal dwell time (tNominal), the calculated time to deliver thedose to the single dwell position, is calculated using the following factors: (Ďnominal) in Gy/min, based on the AAPM Task Group...
... translate the effects observed in these animal models into a clinical benefit in human OA as there are currently no approved disease modifying drugs forthetreatmentof OA A number of protein kinases ... pain responses in animal models Therefore, the inhibition of proinflammatory cytokines may provide an important therapeutic approach forthetreatmentof OA Clinical trial data on cytokine inhibitors ... series of kinase modules beginning with the MAPK kinase kinases (MKKKs), which phosphorylate MAPK kinases (MKKs), which ultimately phosphorylate MAP kinases (MAPK) [1] There are MAPK families, the...
... colistin as monotherapy; she had received intravenous colistin therapy before aerosolized colistin for days and continued to receive the intravenous therapy after the end of aerosolized therapy (for ... agents, as well asthe outcome ofthe infection and ofthe patient R56 The mean age ofthe patients was 59.6 years and most of them were male (six out of eight) All patients had been admitted to the ... least two ofthe following: new onset of purulent sputum, change inthe character of sputum, increased respiratory secretions, or increased requirement for suctioning; new onset or worsening of...
... colistin It is not clear why the more toxic form of colistin was chosen over the better-tolerated colistin sulphamethate Microbiological eradication was attained in four ofthe five patients for ... contrast, was better tolerated and showed less bronchoconstriction [6] In this issue of Critical Care, Michalopoulos and colleagues [7] describe the use of inhaled colistin inthetreatmentof nosocomial ... available (in 50% ofthe patients who received nebulized colistin) Microbiological outcomes forthe remaining three patients are unknown In addition, it was not made clear whether the patients...