hepatic metabolic dysfunctions in type 2 diabetes insulin resistance and impaired glucose production and lipid synthesis
Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot
Ngày tải lên :
07/03/2014, 16:20
... postoperative insulin resistance Insulin resistance in type diabetes Tyrosine phosphorylation of the insulin receptor increased over the same concentration range of insulin in cells from patients with type ... James DE (20 00) Signalling through the insulin receptor Curr Opin Cell Biol 12, 22 2 22 8 Saltiel AR & Kahn CR (20 01) Insulin signalling and the regulation of glucose and lipid metabolism Nature ... have also indicated a role for IRS1 in insulin resistance in adipose tissue (reviewed in [20 ,21 ]) We aimed to compare the insulin resistance of surgical trauma with that in type diabetes and to...
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báo cáo khoa học: " Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes" ppsx
Ngày tải lên :
11/08/2014, 12:20
... differentiation [28 ] Human skeletal muscle insulin resistance and developmental genes Given the chronic nature of skeletal muscle insulin resistance in diabetes and the role of satellite cells in maintaining ... JM: Insulin sensitivity: modulation by nutrients and inflammation J Clin Invest 20 08, 118 :29 92- 30 02 77 Vaag A, Poulsen P: Twins in metabolic and diabetes research: what they tell us? Curr Opin ... Glycaemic instability is an underestimated problem in Type II diabetes Clin Sci (Lond) 20 06, 111:119- 126 84 Karlsson HK, Zierath JR: Insulin signaling and glucose transport in insulin resistant...
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basal insulin therapy in type 2 diabetes
Ngày tải lên :
12/08/2014, 20:59
... NJ]), insulins with an intermediate duration of action (NPH insulin and lente insulin [Lente; Eli Lilly and Company]), and long-acting insulins (ultralente insulin and insulin glargine) Short-Acting ... Basal insulin therapy in type diabetes: 28 -week comparison of insulin glargine (HOE 901) and NPH insulin Diabetes Care 20 01 ;24 :631– HOE 901 /20 04 Study Investigators Group Safety and efficacy of insulin ... effective in mimicking physiologic basal insulin secretion The only currently available long-acting analog is insulin glargine Insulin Glargine Insulin glargine is an extended-action insulin analog and...
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Báo cáo y học: "Efficiency of vibration exercise for glycemic control in type 2 diabetes patients."
Ngày tải lên :
26/10/2012, 10:04
... Vibration Plasma [glucose] pretraining (mg / 100 ml) 120 ± 25 126 ± 23 133 ± 57 Plasma [glucose] posttraining (mg / 100 ml) 115 ± 22 120 ± 22 122 ± 35 Significance n.s n.s n.s HbA1C At baseline the HbA1c ... resistance training improves glycemic control in older patients with type diabetes Diabetes care 20 02; 25 : 1 729 – 36 Fenicchia LM, Kanaley JA, Azevedo JL, et al Influence of resistance training ... Diabetes 1999; 48: 11 92 - 12 Kim HJ, Lee JS, Kim CK Effect of exercise training on muscle glucose transporter protein and intramuscular lipid content in 21 22 elderly men with impaired glucose tolerance...
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Báo cáo y học: "Skeletal muscle sodium glucose co-transporters in older adults with type 2 diabetes undergoing resistance training"
Ngày tải lên :
31/10/2012, 17:08
... characterized by insulin resistance, and thus the inability of insulin to stimulate glucose utilization in skeletal muscle It has been proposed that insulin resistant individuals have a defect in GLUT4 ... randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type diabetes Diabetes Care 20 02; 25( 12) :23 35-41 15 Ivy JL Role of exercise training ... SGLT3, an insulin- independent glucose transport system in skeletal muscle with resistance exercise training hSGLT3 action appears to be independent of the well known GLUT4, insulin- dependent glucose...
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báo cáo hóa học: " Fatness and fitness: how do they influence health-related quality of life in type 2 diabetes mellitus?" docx
Ngày tải lên :
18/06/2014, 19:20
... control in type diabetes: a randomized trial Ann Intern Med 20 07, 147(6):357-69 Hamdy O, Goodyear LJ, Horton ES: Diet and exercise in type diabetes mellitus Endocrinol Metab Clin North Am 20 01, ... mg/dL Mean hemoglobin A1c (SD), % 63.8 (5.6) 46 .2 85.7 38 .2 (9 .2) 24 .1 (5.1) 21 5 .2 (37.5) N/A 56.9 (5.9) 63.3 60 .2 36.0 (7.1) 21 .2 (5.1) 178.8 (40 .2) 6.6 (1.5) < 0.001 0.0 12 < 0.001 0.068 < 0.001 ... mean differences associated with type diabetes -5 .28 - 12. 84 -1.84 -1 .28 -4.86 -8.61 -2. 83 -5.48 -2. 99 -1.33 P value 0.065 < 0.001 0.388 0.5 72 0 .25 9 0.035 0 .28 2 0.0 62 0.004 0.300 Abbreviations: HRQOL...
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Analysis and applications of the km algorithm in type 2 fuzzy logic control and decision making
Ngày tải lên :
09/09/2015, 18:49
... Type- 2 Fuzzy Set 23 2. 2.1 Centroid of a Type- 2 Fuzzy Set 23 2. 2 .2 Centroid of an Interval Type- 2 Fuzzy Set 2. 2.3 The Karnik-Mendel Iterative Algorithm and The ... 42 3 .2 The structure of IT2 FLS 43 3.3 IT2 antecedent FSs: (a) IT2 FSs EN and EP for the input E(n) (P1 = 2L1 θ1 ) (b) IT2 FSs RN and RP for the input R(n) (P2 = 2L2 2 ... singleton, type- 1 or interval type- 2 fuzzy sets As a result, the firing set for each rule is an interval set instead of a type- 1 set and the output of the inference engine is an interval type- 2...
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báo cáo hóa học: " Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" docx
Ngày tải lên :
18/06/2014, 22:20
... I enjoy 12 Insulin means my health will deteriorate 13 Injecting insulin is embarrassing 14 Injecting insulin is painful 15 It is difficult to always inject insulin correctly 16 Insulin makes ... Fear of needle injection Insulin will increase the risk of hypoglycaemia Insulin will improve health Insulin will cause weight gain 10 Insulin will be demanding to administer 11 Insulin means I have ... compared to insulin- treated, with the exception of the item pertaining to weight Here 54% of the insulin- treated agreed that insulin causes weight gain, compared to 23 % in the insulin naïve The...
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báo cáo hóa học:" Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" pdf
Ngày tải lên :
20/06/2014, 16:20
... I enjoy 12 Insulin means my health will deteriorate 13 Injecting insulin is embarrassing 14 Injecting insulin is painful 15 It is difficult to always inject insulin correctly 16 Insulin makes ... Fear of needle injection Insulin will increase the risk of hypoglycaemia Insulin will improve health Insulin will cause weight gain 10 Insulin will be demanding to administer 11 Insulin means I have ... compared to insulin- treated, with the exception of the item pertaining to weight Here 54% of the insulin- treated agreed that insulin causes weight gain, compared to 23 % in the insulin naïve The...
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IMPAIRED CARDIOVASCULAR RESPONSES TO GLUCAGON-LIKE PEPTIDE 1 IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS
Ngày tải lên :
24/08/2014, 12:16
... independently of insulin, and by mechanisms not associated with insulin mediated glucose uptake This is promising since insulin resistance is common among these patients However, the cardiometabolic ... for using insulin to mitigate myocardial injury in an acute setting have been limited Reasons for this limitation include problems associated with the acute use of intensive insulin therapy in patients ... administered into the coronary circulation of isolated rat hearts, and administered intravenously in canines with heart failure However, this insulinomimetic effect occurred within 30 minutes in...
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Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
Ngày tải lên :
25/10/2012, 10:02
... insulin resistance by inducing the release of stress hormones They also alter insulin receptor signalling [ 12- 16] and create insulin resistance Due to these actions, glucose uptake in fat and ... but almost certainly include pre-existing increased insulin resistance and dysfunction of beta cells Insulin resistance is present in the acutely ill [13,15,18 ,28 ] in different intensity, but ... Curr Opin Clin Nutr Metab Care 20 02, 5:551-559 14 Marette A: Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings Curr Opin Clin Nutr Metab Care 20 02, 5:377-383...
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Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
Ngày tải lên :
19/02/2014, 05:20
... exercise in humans J Clin Invest 93, 1654–1660 15 Krebs M & Roden M (20 05) Molecular mechanisms of lipid- induced insulin resistance in muscle, liver and vasculature Diabetes Obes Metab 7, 621 –6 32 16 ... Grigiene J (20 02) Multiple effects of 2, 2,5,5-tetrachlorbiphenyl on oxidative phosphorylation in rat liver mitochondria Toxicol Sci 65, 22 0 22 7 FEBS Journal 27 3 (20 06) 528 8–53 02 ª 20 06 The Authors ... 0.090. 02* * 0.310.04* 0.060.01** 0. 120 .04* 0 .20 0. 02* 0 .21 0.01 0.140. 02 0.460.01 ) 0.030.01 0.060.01 0.130.03 0 .24 0.01 0.090. 02* * 0.300.03* ) 0.040.01 0.150.05* 0 .24 0. 02* * 0 .26 0. 02 0.140. 02* 0.140.01...
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Effectiveness of PRECEDE model for health education on changes and level of control of HbA1c, blood pressure, lipids, and body mass index in patients with type 2 diabetes mellitus docx
Ngày tải lên :
05/03/2014, 22:21
... inhibitors Insulin 14 .2 (10.4-18) 14.4 (10.4-18.4) 0.94 Diuretics 27 .4 (22 .5- 32. 3) 23 .1 (18.3 -27 .9) 0 .23 Beta blockers 12. 9 (9 .2- 16.6) 9.7 (6.4-13.1) 0 .22 ACE inhibitors 30.6 (25 .5-35.7) 29 .1 (24 -34 .2) ... Control PRECEDE 12. 7 12. 3 12. 5 12. 3 0.90 -0 .2 0.85 SBP (
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Long-term Exposure to Traffic-related Air Pollution and Type 2 Diabetes Prevalence in a Cross-sectional Screening-study in the Netherlands pdf
Ngày tải lên :
06/03/2014, 19:20
... 20 02, 23 :599- 622 10 Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM: C-reactive protein, interleukin 6, and risk of developing type diabetes mellitus JAMA 20 01, 28 6: 327 -334 11 Ko K-P, Min ... 1,795 (22 %) 110 (18%) 38 (18%) 1,685 (23 %) 60-65 1,446 (18%) 122 (20 %) 45 (21 %) 1, 324 (18%) ≥ 65 2, 024 (25 %) 29 1 (47%) 1 02 (48%) 1,733 (24 %) BMI (kg·m -2) < 18.5 51 (1%) (1%) (1%) 48 (1%) 18.5 -25 .0 ... contributed to inconsistent findings For instance, the interquartile range for NO2-exposure in this study was only 2. 3 μg/m3, while in previous studies on air pollution and type diabetes [2, 3] this...
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TYPE 2 DIABETES - National clinical guideline for management in primary and secondary care (update) pdf
Ngày tải lên :
08/03/2014, 14:20
... with insulin Insulin therapy Insulin detemir Insulin delivery devices 125 130 146 146 12 12. 1 12. 2 12. 3 Blood pressure therapy Clinical introduction Blood pressure lowering – targets and intervention ... THE GUIDELINE 1.1 1 .2 1.3 1.4 2. 1 2. 2 2. 3 2. 4 2. 5 2. 6 2. 7 2. 8 2. 9 2. 10 3.1 3 .2 Introduction Background Definition Prevalence Health and resource burden 4 Methodology Aim Scope Audience Involvement ... adults and children’, NICE clinical guideline no 43 (20 06) q Type diabetes: diagnosis and management of type diabetes in children, young people and adults’, NICE clinical guideline no 15 (20 04,...
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báo cáo hóa học: " Fear of hypoglycaemia: defining a minimum clinically important difference in patients with type 2 diabetes" docx
Ngày tải lên :
18/06/2014, 19:20
... 16 62 episodes J Diabetes Complications 20 05, 19:10-17 Zammitt NN, Frier BM: Hypoglycemia in type diabetes Diabetes Care 20 05, 28 :29 48 -29 61 Frier BM: Hypoglycemia and cognitive function in diabetes ... 50:1618-1 626 Whitmer RA, Karter AJ, Yaffe K, Quesenberry CP Jr, Selby JV: Hypoglycemic episodes and risk of dementia in older http://www.hqlo.com/content/7/1/91 16 17 18 19 20 21 22 23 24 25 26 27 28 29 ... Hypoglycaemia in type diabetes Diabet Med 20 08, 25 :24 5 -25 4 Banarer S, Cryer PE: Gypoglycemia in type diabetes The Medical Clinics of North America 20 04, 88:1107-1116 Boyle PJ, Zrebiec J: Physiological and...
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báo cáo hóa học: " A comparison of EQ-5D index scores using the UK, US, and Japan preference weights in a Thai sample with type 2 diabetes" pdf
Ngày tải lên :
18/06/2014, 19:20
... 6.53 4.10 300,000 2. 43 123 ,457 1 .23 6.94 4.40 300,000 2. 54 118,110 5.51 6.68 4 .21 300,000 2. 47 121 ,457 2. 83 6. 62 4.17 300,000 2. 45 122 ,150 2. 28 7.05 4.49 300,000 2. 56 117,096 6. 32 Decision tree ... Literature review and proposed guidelines J Clin Epidemiol 1993, 46:1417-14 32 16 17 18 19 20 21 22 23 24 25 26 Kaplan RM, Feeny D, Revicki DA: Methods for assessing relative importance in preference ... EQ-5D index scores derived from the US and UK population-based scoring functions Med Decis Making 20 07, 27 : 321 - 326 Huang IC, Willke RJ, Atkinson MJ, Lenderking WR, franngakis C, Wu AW: US and UK...
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báo cáo hóa học: " Outcomes of adding second hypoglycemic drug after metformin monotherapy failure among type 2 diabetes in Hungary" potx
Ngày tải lên :
18/06/2014, 19:20
... n = 73 7.3 ± 1 .2 24.88% 7.4 ± 1.3 23 .75% 7.0 ± 1 .2 30.14% 3.16% 3 .24 % 2. 78% 57. 52% 16 .26 % 0 .24 % 0.73% 11.89% 5.83% 1.46% 2. 91% 69. 12% 3 .24 % 0 .29 % 0.88% 12. 65% 7.06% 0.59% 2. 94% 2. 78% 77.78% 0.00% ... Med Res Opin 20 07, 23 :1493-1507 Strowig SM, Raskin P: Combination therapy using metformin or thiazolidinediones and insulin in the treatment of diabetes mellitus Diabetes Obes Metab 20 05, 7:633-641 ... attributable to diabetes: realistic estimates for the year 20 00 Diabetes Care 20 05, 28 :21 30 -21 35 Global Guideline for Type Diabetes INTERNATIONAL DIABETES FEDERATION, 20 05 20 05 Ref Type: Electronic...
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báo cáo hóa học: " Additional impact of concomitant hypertension and osteoarthritis on quality of life among patients with type 2 diabetes in primary care in Germany – a cross-sectional survey" doc
Ngày tải lên :
18/06/2014, 19:20
... (18.84) 46.93* (19. 42) 77.69 (23 . 82) 81.47 (22 . 52) 71.60* (26 .99) 74 .25 (26 .78) 66.83 (43.91) 82. 52 (35.08) 62. 45 (44.46) 68.06 (44. 92) 69 .21 (21 .25 ) 72. 79 (17.88) 65.68 (18.33) 66.35 (20 .83) 43.45 ... 72. 21 (40 .26 ) 41.46* (44.56) 45.50* (45. 12) 66.94 (30 .26 ) 72. 89 (27 .01) 44 .21 *** (21 .54) 44.60*** (23 .99) 55. 82 (20 .17) 57.79 (17.15) 50.46* (17.06) 49.13** (18. 02) 52. 09 (23 .78) 58.33 (21 .05) 47.98 ... and osteoarthritis (n = 97) Diabetes, hypertension and osteoarthritis (n = 27 1) RP BP GH VT SF RE MH PCS MCS 65.77 (30.44) 70. 02 (26 .14) 49.99 *** (27 .90) 53.08 *** (28 .04) 62. 42 (44 .20 ) 72. 21...
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báo cáo hóa học:" Factors associated with psychological and behavioral functioning in people with type 2 diabetes living in France" pptx
Ngày tải lên :
20/06/2014, 15:20
... 0.98 1 .22 0. 42 0.008 - 2. 16 1.10 0.05 0. 02 - 2. 20 1 .28 < 001 0.09 < 001 0.10 Insulin - 9.49 1 .23 < 001 - 8.54 1.94 < 001 - 3.35 1.61 0.04 Insulin & OHAs - 8.79 1. 32 < 001 - 2. 43 1.97 0 .22 - 1.64 ... life in type diabetes Diabetologia 20 06, 49:1489-1497 Boini et al Health and Quality of Life Outcomes 20 10, 8: 124 http://www.hqlo.com/content/8/1/ 124 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 ... November 20 10 References Prevalence of Diabetes [http://www.who.int /diabetes/ en/] Numéro spécial consacré au diabète Editorial [http://www.invs.sante.fr/ beh /20 02/ 20 _21 /beh _20 _21 _20 02. pdf] Nazimek-Siewniak...
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