... Patterns of T -cell reconstitution by assessment of T -cell receptor excision circle and T -cell receptor clonal repertoire after allogeneic hematopoieticstemcelltransplantationinleukemia patients–a ... ability of T -cell immune reconstitution more precisely, and may be beneficial in evaluating T -cell reconstitution inacuteleukemia patients after allo-HSCT Acknowledgements Supported by China Postdoctoral ... impaired naive T -cell survival following allogeneic hematopoieticstemcelltransplantationin the absence of chronic graft-versus-host disease Blood 2003, 102:4600-7 10 Li Y, Yin Q, Yang L, Chen...
... http://www.jhoonline.org/content/4/1/9 Page of Figure Bilirubin level during chemotherapy and allogeneic hematopoieticstemcelltransplantation Chronological dates of the treatment courses were indicated ... Caspofungin for prophylaxis of fungal infections] Tropisetron was used during the chemotherapy and conditioning (E) period of acute GVHD [alanine aminotransferase 321 U/L, aspartate aminotransferase ... after transplantation, although indirect hyperbilirubinemia repeatedly happened during chemotherapy with daunorubicin, idarubicin, and cytarabine prior to HSCT This may suggest that fludarabine...
... marrow stemcelltransplantation for severe systemic lupus erythematosus of long duration Lupus 1997, 6:545-548 Burt RK, Traynor A, Ramsey-Goldman R: Hematopoietic stemcell transplantation for systemic ... systemic lupus erythematosus Rheumatology 1999, 38:767-772 Burt RK, Slavin S, Burns WH, Marmont A: Induction of tolerance in autoimmune disease by hematopoieticstemcell transplantation: getting ... hematopoieticstem cells are infused in order to shorten the past transplant neutropenic interval by 4–6 days compared with the same dose of cyclophosphamide without hematopoieticstemcell support,...
... n = 42 in the non-intensive phase), ** self-reports (n = 22 in intensive treatment and n = 24 in non intensive treatment); proxy-reports (n = 31 in intensive treatment and n = 33 in non intensive ... determinants: monthly income level of parents and assigned hospital class during the diagnostic process Both determinants are obtained routinely during admission to the clinic and recorded in the ... assess the HRQOL in childhood acutelymphoblasticleukemia (ALL) patients in Indonesia and to assess the influence of demographic and medical characteristics on HRQOL Methods Setting Indonesia is...
... n = 42 in the non-intensive phase), ** self-reports (n = 22 in intensive treatment and n = 24 in non intensive treatment); proxy-reports (n = 31 in intensive treatment and n = 33 in non intensive ... determinants: monthly income level of parents and assigned hospital class during the diagnostic process Both determinants are obtained routinely during admission to the clinic and recorded in the ... assess the HRQOL in childhood acutelymphoblasticleukemia (ALL) patients in Indonesia and to assess the influence of demographic and medical characteristics on HRQOL Methods Setting Indonesia is...
... GVHD is initiated, T-cells produce additional proinflammatory cytokines, including tumor necrosis fac tor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-2, which in turn attract more T-cells ... (Th2) cells can initiate a response against autoantigens leading to B -cell hyperre activity and production of autoantibodies, causing targetorgan damage, including skin, mucosa, eyes, joints, ... Consensus recom mends a system for scoring chronic GVHD manifestations in organs and sites, including the skin, mouth, eyes, gastro intestinal tract, liver, lungs, joints and fascia, genital...
... blood cell or a brain cell During this last decade, the number of published articles or books investigating the role of stem cells incelltransplantation or regenerative medicine increased remarkably ... transplanted stem cells in the host In conclusion, CellTransplantation is bridging celltransplantation research in a multitude of disease models as methods and technology continue to be refined The ... killer cell allor‐ ecognition of missing self in allogeneic hematopoietic transplantation: a tool for im‐ 29 30 Innovations inStemCellTransplantation munotherapy of leukemia Curr Opin Immunol...
... RNA binding protein and stemcell marker Inhibitor of microRNA processing in embryonic stem (ES) and carcinoma (EC) cells Table Combinations of the genes that have been used to obtain the induced ... factors into somatic cells By using these viral delivery systems, 12 New Advances inStemCellTransplantation Fig Methods for producing induced pluripotent stem cells (iPSCs) by non-integrating ... factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cells Stem Cells 27, 30013011 22 New Advances inStemCellTransplantation Rai, K., Huggins, I.J., James,...
... by the inclusion of subgroups that have been understudied in prior stemcell transplant survivorship research, including Spanish speakers, and individuals undergoing reduced intensity transplantation ... current status of hematopoieticcelltransplantation Annu Rev Med 2003, 54:491-512 Horowitz MM: Uses and growth of hematopoieticcelltransplantationIn Thomas’ hematopoieticcelltransplantation ... in survival rates after allogeneic hematopoietic stem- celltransplantation for acute and chronic leukemia by ethnicity in the United States and Canada J Clin Oncol 2003, 21(20):3754-3760 10 Pidala...
... grouped into four sections: 1) Hematopoieticstemcell properties, 2) Regulation of hematopoieticstem cells, 3) Hematopoieticstem cells in aging and disease, and 4) Hematopoieticstemcell therapy ... signaling in the niche enforces hematopoieticstemcell quiescence and is necessary to preserve self-renewal in vivo CellStemCell Mar 6;2(3):274-83 Fuchs, E.(2008) Skin stem cells: rising to ... stimuli trigger intrinsic determinants of cell fate, the transcription factors which contribute to the reprogramming of HSCs into cell- Advances inHematopoieticStemCell Research lineage restricted...
... Das-Gupta E, Russell N: Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia Clin Cancer Res 2004, 10:2675-2680 Dufloth ... of stemcell infusion Discussions and Conclusions Here we report a case of a secondary AML developing from donor-derived cells in a breast cancer patient who underwent allogeneic stemcelltransplantation ... polymorphisms in the patient’s pre- and post -transplantation (AML) cells and donor’s cells Polymorphism DNA repair mechanism Patient cells (pretransplantation) AML cells (posttransplantation) Donor cells...
... allogeneic stemcell transplantation, severe disease is rare in patients after autologous stemcelltransplantation Nevertheless, in patients with severe complications of infections after autologous stem ... after hematopoieticstemcelltransplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious ... of integrated human herpesvirus-6 in allogeneic hematopoieticstemcelltransplantation Bone Marrow Transplant 2007, 40:563-566 Competing interests The authors declare that they have no competing...
... allogeneic stemcell transplantation, severe disease is rare in patients after autologous stemcelltransplantation Nevertheless, in patients with severe complications of infections after autologous stem ... after hematopoieticstemcelltransplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious ... of integrated human herpesvirus-6 in allogeneic hematopoieticstemcelltransplantation Bone Marrow Transplant 2007, 40:563-566 Competing interests The authors declare that they have no competing...
... not included in the lineage cocktail After incubating for 20 min, wash the cells twice by diluting in staining medium followed by centrifugation The cells can now either be pre-enriched using ... sorted, complete the staining by incubating in streptavidin conjugated to Texas Red or PharRed for 15–20 on ice After washing, resuspend the cells in staining medium containing a viability dye (PI ... the cell suspension, including biotinylated anti-Sca-1, APC-conjugated anti-Mac-1, and FITC-conjugated anti-Thy-1.1 After incubating for 20 min, wash the cells twice by diluting in staining medium,...
... is found in the RPE cells in our study However, the depolarization-induced DA release is not detected in the cells, indicating that the DA release machinery as seen in most excitable cells is ... brain injection on a stereotaxic frame (Myneurolab, USA) 6-OHDA (6 μg in μl) was dissolved in normal saline containing ascorbic acid (0.2 mg/ml), and injected into the right medial forebrain ... peroxidase-coupled avidin-biotin staining kit (ABC kit, Vector Laboratories, UK) were used For HE staining, the tissue sections were submerged into the hematoxylin solution (0.5% hematoxylin, 5% aluminium ammonium...
... population of stem/ progenitor cells in the breast cancer (MCF7) cell line [11] The fact that the vast majority of MCF7 stemcell enriched SP cells express MUC1 suggests that epithelial cancer stem cells ... overexpressed cells behave like cancer stem cells which are capable of maintaining the self-renewal property (Figure 5) Figure Colony formation in MUC4-trasfected cells SKOV3-Vector and SKOV3-MUC4 cells ... have further shown an increased expression of stemcell regulatory genes, increased invasion in vitro and increased tumorigenesis in NOD/SCID mice [10] This suggests that, in addition to genetic...
... Sources of Stem Cells for Tissue Repair Different types of stem cells include embryonic stem (ES) cells, umbilical cord blood stem cells, organ-specific somatic stem cells (e.g., neural stem cells ... pluripotent stem cells from spermatogonia in the adult human testis, providing another strategy for obtaining genetically identical stem cells Umbilical cord blood stem/ progenitor cells are associated ... brain Substantial efforts have therefore been devoted to obtaining more pluripotent stemcell populations, such as bone marrow mesenchymal stem cells (MSCs) or adipose stem cells, for use in...