gross anatomy of the human heart pdf
anatomy of the human body - henry gray
Ngày tải lên :
08/04/2014, 12:35
...
VII. The Veins
1. Introduction
2. The Pulmonary Veins
3. The Systemic Veins
a. The Veins of the Heart
b. The Veins of the Head and Neck
1. The Veins of the Exterior of the Head and Face
2. The ... Anatomy of the Human Body. 1918.
7. The Notochord
The notochord (Fig. 19) consists of a rod of cells situated on the ventral aspect of the neural tube; it
constitutes the foundation of the ... of the Neck
3. The Diploic Veins
4. The Veins of the Brain
5. The Sinuses of the Dura Mater. Ophthalmic Veins and Emissary Veins
c. The Veins of the Upper Extremity and Thorax
d. The Veins of...
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Báo cáo khoa học: The protein shuffle Sequential interactions among components of the human nucleotide excision repair pathway pdf
Ngày tải lên :
07/03/2014, 12:20
... late steps of the process. For example, early in the
NER process, RPA assists TFIIH in the opening of
the DNA helix around the damage site [36]. Further-
more, in the presence of the XPA minimal ... sites.
Taken together, these findings suggest that the struc-
tural properties of DNA-damaged substrates, whether
intrinsic or the result of protein binding, function in
the recruitment of the XPC–hHR23B ... Binding of XPG induces the release
of XPC–hHR23B, whereas XPF–ERCC1 triggers exci-
sion of the damaged DNA and the release of XPA
and TFIIH. Subsequently, the newly formed gap in
the DNA is filled by...
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Báo cáo Y học: Activation of transcription of the human presenilin 1 gene by 12-O-tetradecanoylphorbol 13-acetate pdf
Ngày tải lên :
08/03/2014, 09:20
... increases the rate of transcription initiation
of the PS1 gene in SK-N-SH cells
To determine whether the increase in the level of PS1
mRNA results from the activation of the transcription of
the gene ... in the presence of TPA. Thus the increase in the
level of PS1 mRNA observed by Northern blotting of total
cellular RNA results from an increase in the rate of
initiation of transcription of PS1.
PS1 ... interactions of the )10
region of the PS1 promoter with nuclear factors, including
the amount of complexes involving Ets1/2 factors.
DISCUSSION
The loss of PKC is a prognostic element in the severity of
neuronal...
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Báo cáo khoa học: Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2¢ of substrates pdf
Ngày tải lên :
22/03/2014, 21:21
... number of poten-
tial substrates during the screening of the full human
proteome. This highlights the importance of factors
other than the extended cleavage specificity in deter-
mining whether ... in 6%
of the sequences. Thus, Arg143 and Lys192 contribute
almost equally to the P2Â specicity of HC. Mutating
either of the two basic amino acids in these positions
partially disrupts the acidic ... or
Glu, but attract these residues equally well, probably
solely on the basis on the negative charge of their side
chains.
Verifying the consensus sequence by the use of a
new type of recombinant...
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Báo cáo khoa học: Alanine screening of the intracellular loops of the human bradykinin B2 receptor – effects on receptor maintenance, G protein activation and internalization pdf
Ngày tải lên :
29/03/2014, 23:20
... Although
the processes of signaling and regulation of human
B
2
R are, in general, fairly well understood, the knowl-
edge of the molecular basis of these events at the struc-
tural level of the receptor ... through
changes in the overall structure of the receptor. Thus,
these data demonstrate the connection between the
structure of ICLs and that of the binding site, implying
reciprocally that changes at the binding ... the respective construct name next to them. The point
mutations E66A in the first loop and T242A at the end of the third loop are also indicated. The two-dimensional structure of B
2
R, with the
membrane...
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Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA pdf
Ngày tải lên :
30/03/2014, 11:20
... in
the regulation of these genes. It should be noted that,
although the exact positions of the AREs are not con-
served between different mammalian species, at least
50% of all AREs in all of these ... bars)
shows the results of analysis of 8-oxoG in the control
and KD-1 cells. In the KD-1 cells, the concentration
of endogenous 8-oxoG was significantly increased,
indicating that PRDX5 contributed to the ... silencing of the human
PRDX5 gene, we also constructed stable clones of the
cultured airway epithelial cell line A549, which has
significant down-regulation of this gene clone, and
analyzed the concentration...
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Báo cáo khoa học: Thioredoxin reductase from the malaria mosquito Anopheles gambiae Comparisons with the orthologous enzymes of Plasmodium falciparum and the human host pdf
Ngày tải lên :
31/03/2014, 07:20
... [34] between the fruit fly and the mosquito, not only
the basic principles of redox metabolism and the genomic
organization of the TrxR gene, but also the mechanistic
peculiarities of these orthologous ... support the assumption that the
substitution of the Trx system for GR, as well as the
mechanistic particularities of the TrxR, are a common
principle in dipteran insects. In the context of the malarial
system, ... reaction of the cata-
lytic cycle, of course, represents the net reaction catalyzed by
TrxR.
Discussion
The isolation and characterization of A. gambiae TrxR
contributes to the understanding of the...
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Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
Ngày tải lên :
03/11/2012, 09:54
...
all of the OLP epithelium. The count was performed by two investigators without knowledge of
whether the samples were control or experimental. The total number of basal and suprabasal epithelial ... Negative controls consisted of omission of the
primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit
serum instead of the primary antibody.
Cell quantification ... OLP
would require an increased immunolocalization of hMSH2. Therefore, the reduced expression of
hMSH2 protein could make the epithelium of OLP more susceptible to DNA mutation, making it prone...
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Tài liệu Decision Analysis and Risk Management: Two Sides of the Same Coin pdf
Ngày tải lên :
10/12/2013, 17:15
... based on analysis of risk. The thoroughness of the analysis determines the
“quality” of the decisions.
High quality decisions are not the best decisions in hindsight. They are the best decisions ... decisions in which the magni-
tude of the risk of being wrong is understood.
The quality of decisions can therefore be judged by the degree to which uncertainties (risks) are considered in
the decision ... then related to the four steps of the decision making process and finally to
the three types of error (risk) that occur in each of the four steps.
The paper concludes with an example of how methodical...
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