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green apos s functions and their relations

Synthesis of mannoside glycans of phosphatidylinositol mannosides (PIMs

Synthesis of mannoside glycans of phosphatidylinositol mannosides (PIMs

Cao đẳng - Đại học

... MANNOSIDES (PIMs) Part A: Synthesis of Mannoside Glycans of Phosphatidylinositol Mannosides (PIMs) Background and Introduction 1.1 Phosphatidylinositol Mannosides (PIMs) and Tuberculosis Tuberculosis ... of Tri- and Tetramannosides 16   Part A: Synthesis of Mannoside Glycans of Phosphatidylinositol Mannosides (PIMs) 3.5.3 Synthesis of Petamannosides of PIMs TMSOTf promoted Schmidt glycosylation ... Bielschowskysin Macrocycles: Synthesis of Building Blocks 3.1 Towards Bielschowskysin 114  3.1.1 Bielschowskysin: Retrosynthesis I 114  3.1.2 Alkyne Synthon: 1st Generation Synthesis...
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Báo cáo khoa học: New insights into the functions and N-glycan structures of factor X activator from Russell’s viper venom pot

Báo cáo khoa học: New insights into the functions and N-glycan structures of factor X activator from Russell’s viper venom pot

Báo cáo khoa học

... (Waters Micromass, Manchester, UK) and 4700 Proteomics Analyzer (Applied Biosystems), exactly as described previously [40] LC-MS/MS analysis of glycopeptides Online nanoLC-nanoESI-MS/MS analyses ... contributing to Lewis (Le) and sialyl-Lewis (SLe) epitopes was also identified, and their functional implications were clarified by in vivo studies Results and Discussion Purification and characterization ... for structural assignment In general, the same molecular ion signals afforded by heavy and light chains gave similar MS/MS spectra, indicative of similar structures Representative MS/MS spectra...
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Báo cáo khoa học: Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is a-D-Gal-(1fi3)-a-D-GalNAc pot

Báo cáo khoa học: Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is a-D-Gal-(1fi3)-a-D-GalNAc pot

Báo cáo khoa học

... each species These data demonstrate the feasibility of chemically synthesizing peptides, such as tx5a, that possess multiple post-translational modifications This synthesis in and of itself is a significant ... configuration is not the same as that previously discovered and reported for contulakin-G (Conus geographus) This surprising result establishes that the O-glycosylation of serine and threonine residues in ... matrix assisted laser desorption mass spectrometry (MALDI-MS) measurement of both components resulted in intense species consistent with the correct product (see below) Both the hydrophilic and hydrophobic...
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Báo cáo khoa học: N-Glycan structures of squid rhodopsin Existence of the a1–3 and a1–6 difucosylated innermost GlcNAc residue in a molluscan glycoprotein pot

Báo cáo khoa học: N-Glycan structures of squid rhodopsin Existence of the a1–3 and a1–6 difucosylated innermost GlcNAc residue in a molluscan glycoprotein pot

Báo cáo khoa học

... glycoproteins [25] Molluscan rhodopsin possesses only one N-glycosylation site, whereas frog, bovine, and human (and possibly other mammalian) rhodopsin molecules have conserved two N-glycosylation sites ... into glycans A, B2 and C after treatment with b-galactosidase, a-mannosidase and a-L-fucosidase, respectively mannose residues As reference compounds corresponding to these candidates were not ... (A) and further identification of linkage position by GC-EI-MS analysis (B) The MS/MS fragment ions were assigned as shown schematically The EI-mass spectrum for the 4-linked Fuc peak is shown...
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Báo cáo khoa học: Glycan profiling of urine, amniotic fluid and ascitic fluid from galactosialidosis patients reveals novel oligosaccharides with reducing end hexose and aldohexonic acid residues ppt

Báo cáo khoa học: Glycan profiling of urine, amniotic fluid and ascitic fluid from galactosialidosis patients reveals novel oligosaccharides with reducing end hexose and aldohexonic acid residues ppt

Báo cáo khoa học

... glycosphingolipids in humans Results Glycans from seven urine samples from six galactosialidosis patients, five amniotic fluid samples from five mothers carrying a fetus suffering from galactosialidosis, and ... oligosaccharides in galactosialidosis aminidase and N-acetylgalactosamine-6-sulfate sulfatase (EC 3.1.6.4) [3,4] Galactosialidosis is characterized by excessive excretion of sialyloligosaccharides ... a-neuraminidase and b-galactosidase in patient cells Several activity studies on the structural analysis of sialyloligosaccharides from urine of galactosialidosis patients [10,11] have been published...
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Báo cáo khoa học: Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan Glycoengineering for enhanced cell binding and serum clearance of the neoglycoprotein pot

Báo cáo khoa học: Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan Glycoengineering for enhanced cell binding and serum clearance of the neoglycoprotein pot

Báo cáo khoa học

... three different assay systems Affinity to purified lectins/antibodies The first assay system was designed to simulate properties of glycoproteins presented on a cell surface by adsorbing the neoglycoprotein ... technical assistance, to Dr S Namirha for helpful discussion and to the Deutsche Forschungsgemeinschaft, the Dr M.-Scheel-Stiftung fur Krebs¨ forschung, the Fonds der Deutschen Chemischen Industrie, ... a2,3 ⁄ a2,6-sialylated derivatives: their preparation, assessment of their ligand properties for purified lectins, for tumor cells in vitro, and in tissue sections, and their biodistribution in...
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History Of Modern Biotechnology II

History Of Modern Biotechnology II

Sinh học

... pure physiologists is growing steadily as more and more details of the transport processes and the kinetics involved in the morphogenesis become known A short survey of these results is presented ... dynamics and transfer processes 2.2 Macroscopic Total Mass, Elemental Mass, Energy and Entropy Balances Interrelations between the rates of growth, product synthesis, respiration, and substrate consumption ... production strains in shaking flasks and laboratory fermentors was investigated to optimize process conditions and the composition of media on the basis of process kinetic analyses, as well as to elucidate...
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History of Modern Biotechnology I - Springer

History of Modern Biotechnology I - Springer

Sinh học

... fresh fruit, and carcasses as objectionable as possible to large organisms in the shortest amount of time Among their strategies is the production of secondary metabolites such as antibiotics and ... daltons Whereas primary metabolism is basically the same for all living systems, secondary metabolism is mainly carried out by plants and microorganisms and is usually strain-specific The bestknown ... agents The Natural Functions of Secondary Metabolites in animals, phosphinothricins as herbicides, spinosyns as insecticides, and cyclosporin as an immunosuppressant Cyclosporin A virtually revolutionized...
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09 Physical and Chemical Characteristics of DDGS revisions.

09 Physical and Chemical Characteristics of DDGS revisions.

Sinh học

... moisture content of DDGS is usually between 10-12%, there is minimal risk of spoilage during transit and storage unless water leaks into transit vessels or storage facilities No research studies ... factor to consider when determining the storage volume of transport vehicles, vessels, containers, totes and bags Bulk density affects transport and storage costs Low bulk density ingredients have ... Physical & Chemical Characteristics of U .S DDGS Physical and chemical characteristics of distiller s dried grains with solubles (DDGS) vary among sources and can influence its feeding value and...
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Use of DDGS in Swine Diets

Use of DDGS in Swine Diets

Sinh học

... feedstuffs for swine Purdue University, Factsheet 112 Smelski, R.B and S. C Stothers 1972 Evaluation of corn distillers dried grains with solubles for finishing pigs Proc Western Sec Am Soc Anim Sci ... past 60 years, research has been conducted to evaluate three types of distiller s co-products in swine diets – distiller s dried solubles (DDS), distiller s dried grains (DDG) and distiller s ... Use of U .S DDGS in Swine Diets Historical Use of DDGS in Swine Diets Historically, limited amounts (less than 3% of total production) of distiller s co-products were used in swine diets until...
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