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glutathionylspermidine is an intermediate formed in the biosynthesis of trypanothione

Báo cáo khoa học: An intermediate step in the evolution of ATPases ) the F1F0-ATPase from Acetobacterium woodii contains F-type and V-type rotor subunits and is capable of ATP synthesis Michael Fritz and Volker Muller ¨ docx

Báo cáo khoa học: An intermediate step in the evolution of ATPases ) the F1F0-ATPase from Acetobacterium woodii contains F-type and V-type rotor subunits and is capable of ATP synthesis Michael Fritz and Volker Muller ¨ docx

Báo cáo khoa học

... cells is compet-ent in ATP synthesis, despite its unusual and uniquemembrane-embedded motor. This is the starting pointfor a detailed analysis of the stucture and function of the rotor of the ... specific ATPase activity of the complete enzymewas in the range 5–9.9 UÆmg)1protein, depending on the batch. This is in the same range as the one deter-mined previously with the incomplete enzyme ... twohairpins [20]. Most important, the ion-binding site is not conserved in hairpin 1. If one assumes the samenumber of hairpins in V0and F0, the rotor of V1V0-ATPases has only half the...
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Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

Báo cáo khoa học

... andC-terminal helices of the c ring, respectively. The C-terminal helices show a clear handedness, and two of the rings face in the opposite direction in the membrane to the other two, forming the same patternas ... one of the negative charges on the ring and thus keeps the ring in place [34–36]. How-ever, the system is not stiff but instead the ring idles in front of the positive charge. This site is accessible ... rotor. The stator is formed by subunits aand b2, and the rotor is formed from multiple copies of subunit c. They form an oligomeric ring of non-covalently linked subunits, and rotation of the...
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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

Báo cáo khoa học

... from the thiazoliumring of the cofactor to the surface of the protein. The entrance of the active site cleft is covered by the C-terminalhelix and this part of the polypeptide chain must move in order ... structure of the corresponding intermediate in transketolase [37] and the model derived for ScPDC [38] (Fig. 6). In the immediatevicinity of the modelled a-carbanion/enamine, there are anumber of invariant ... conformational changes duringcatalysis, and these structural features explain the lack of substrateactivationinZmPDC.InIPDC,theassemblyof the subunits in the tetramer resembles that of ZmPDCrather than ScPDC....
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf

Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf

Báo cáo khoa học

... lacA is also detected in the presence of these compounds, but in the presence of D-xyloseand xylan as well. This can be explained by the structure of the polysaccharides. Xylan contains single ... consists of 99%D-galactose and0.3%L-arabinose and is predominantly linear. Potatoarabinogalactan consists of 86%D-galactose and 6.6%L-arabinose, while soy arabinogalactan consists of ... control of the xylanolytic activator protein [32,41]. The increase in expression levels of galA in the CREA mutant,indicates that at least one of the detected putative CREAbinding sites in the...
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Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc

Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc

Báo cáo khoa học

... pUZ8002 bearing the cosmidwith oriT and the S. coelicolor DdesA mutant, single cross-over exconjugants were screened for kanamycin resistance.Kanamycin-resistant colonies were isolated and analysed ... for the treatment of iron overload duringmetabolic alterations in humans. Initial work on the biosynthesis of desferrioxamine B in S. pilosus indica-ted that the first step in the desferrioxamine ... RT-PCRanalysis, and there is overlapping of the desB transla-tion termination triplet with the ATG of desC and also of desC and desD (so-called translational coupling);moreover, there are no intergenic...
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Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf

Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf

Báo cáo khoa học

... additional genes encoding other proteinsimplicated in the biosynthesis of the aminonucleoside moiety of A201A. Here we report the sequencing of a total of 6946 bp, which include the ata genes most ... unit to the ketosynthetasedomain of the PKSs for polyketide biosynthesis [35].Therefore, AtaPKS1 could be an acyltransferase, whichshould be implicated in the biosynthesis of the A201Apolyketide ... Saccharopolyspora erythraea ,the erythromycin-producing organism, has permitted the isola-tion of Streptomyces antibioticus genes implicated in oleandomycin biosynthesis [40].Gene analyses and enzymatic assays...
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Báo cáo

Báo cáo " Using Bloom’s revised taxonomy to design in-class reading questions for intermediate students in the context of Vietnam " ppt

Báo cáo khoa học

... organization of the information - Infer and/or predict - Paraphrasing/Translating - Exemplifying, comparing and contrasting, and classifying - Intermediate Skimming, Surveying - Intermediate ... Summarize the text above within 70 words (Intermediate Skimming and Surveying) Q4: On the same chart, use two lines to present the supply and the demand in the two tables above. Is there any intersection ... primarily involved recalling and understanding the provided information (lower-level of cognitive domain, Bo-Linn [1]) and left a large gap on applying, analyzing, synthesizing, evaluating and...
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Báo cáo khoa học: Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis pptx

Báo cáo khoa học: Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis pptx

Báo cáo khoa học

... topromote the transfer of the p-HB moiety ontoPKS15 ⁄ 1 [16,18].To examine the involvement of FadD29 in the bio-synthesis of DIMs and PGLs, we took advantage of the existence in the laboratory of an ... addition, the possibleredundancy of these proteins in the activation of the various intermediates in DIM and PGL biosynthesis has not been analyzed. This study was undertaken todissect the roles of ... this progress in our knowledge of the bio-synthesis of DIMs and PGLs, the in vivo functions of these FadD proteins in this pathway remain to beestablished and ⁄ or completed. For instance, the involvement...
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Báo cáo khoa học: Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids ppt

Báo cáo khoa học: Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids ppt

Báo cáo khoa học

... observed in the biosynthesis of colneleic acid (Table 1, Fig. 2).Stereospecificity of hydrogen eliminations fromC14 in the biosynthesis of etheroleic acid isomers In the biosynthesis of etheroleic ... [20,21], thromboxane synthase[22] and prostacyclin synthase [22]. In the case of divi-nyl ether biosynthesis, the initial step is believed toconsist of cleavage of the O-O bond of the hydroper-oxide ... step of divinyl ether fatty acid biosynthesis. (A) Divinyl ether synthasesfrom potato, garlic or Ranunculus lingua introducing an ‘E’ vinylether double bond, (B) divinyl ether synthases from Ranunculusacris...
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Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt

Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt

Báo cáo khoa học

... therefore of interest with respect to under-standing the mode of assembly and pinpointing the mechanism by which metals guide the path of aggre-gation away from the fibrillar trail. The present investigation ... morphologically distin-guish aggregates formed in the presence of Cu2+fromthose formed in the presence of Zn2+.Taken together, these results suggest that Ab aggre-gates formed in the presence of Cu2+or ... assembled, the N-terminal metal-binding region of the peptide will be in close proximityto both the C-terminal and turn residues, possiblyinterfering with these regions. This explains how an altered...
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Báo cáo khoa học: Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide ppt

Báo cáo khoa học: Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide ppt

Báo cáo khoa học

... patients. To investigate the function of the glycosyltransferase enzymes involved in the biosynthesis of lipooligosaccha-ride of M. catarrhalis and to gain some insight into the mechanism of sero-type ... irradiatingeach of the anomeric signals in turn to obtain the 1H chemicals shifts of the corresponding remainingring protons. Again, assignment of the Kdo residuewas possible from examination of ... being retained at the terminal position of the (1 fi 4) chain. Additionally, the MS sugar analysisclearly indicated the absence of the GlcNAc residue.Instead, in the absence of Lgt4 and Lgt5, a glucose...
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Báo cáo khoa học: Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus potx

Báo cáo khoa học: Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus potx

Báo cáo khoa học

... althoughweakly, on the geranylgeranyl group of GGGP andGGPP. These facts strongly suggest the involvement of the enzyme, A. fulgidus GGR, in the biosynthesis of membrane lipids.ResultsRecombinant expression ... biosynthesis of isoprenoid compounds, such asarcheal membrane lipids and respiratory quinones. On the other hand, phytyl diphosphate produced by plantGGR is actually used in the biosynthesis of ... clearly indica-ting that menaquinone and ubiquinone are not prefer-able substrates for the enzyme [21]. These factsstrongly suggest the involvement of the enzyme, GGR, in the biosynthesis of membrane...
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Báo cáo khoa học: Accessory proteins functioning selectively and pleiotropically in the biosynthesis of [NiFe] hydrogenases in Thiocapsa roseopersicina docx

Báo cáo khoa học: Accessory proteins functioning selectively and pleiotropically in the biosynthesis of [NiFe] hydrogenases in Thiocapsa roseopersicina docx

Báo cáo khoa học

... kDa) and the transposon is inserted intoTable 2. Identity between the accessory proteins of T. roseopersicina and the corresponding proteins from other organisms.OrganismT. roseopersicinaHupK ... roseopersicina and to understand their physio-logical roles. The determination of the specificity of the accessory proteins is a challenging exercise in this micro-organism because of the presumed ... the processing of the HupL subunit [15]. It is plausible toassume that HynD is involved in the maturation of the HynL protein. Indeed, in the strain harboring the Tn5transposon-inactivated...
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Báo cáo khoa học:

Báo cáo khoa học: "An Intermediate Representation for the Interpretation of Temporal Expressions" ppt

Báo cáo khoa học

... andapplications. In Proceedings of the 40th Anniver-sary Meeting of the ACL.R. Dale and P. Mazur. 2006. Local semantics in the interpretation of temporal expressions. In Proceed-ings of the ... is then tocompute as much of the semantic content of a tem-poral expression as can be determined on the basis of the expression itself, producing an intermediate partial representation of the ... as violating the strong separation; rather, wedistinguish the two steps of the process in terms of the extent to which they make use of contextual in- formation in computing values. Then, recognitionis...
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Báo cáo sinh học:

Báo cáo sinh học: " Recombinant Tula hantavirus shows reduced fitness but is able to survive in the presence of a parental virus: analysis of consecutive passages in a cell culture" pot

Điện - Điện tử

... variantand that the lower fitness of the recombinant virus can notbe increased by pre-passaging in cell culture. The observedsurvival time of the recTULV in the presence of the Monitoring of ... recombinant would have fair chances tosurvive. The existence of wt recombinant strains of TULV[10] supports this way of reasoning. Evidence for the recombination in the hantavirus evolution continues ... in a hypothetical in vivo situation, from one rodentto another. If transmission is performed in a sampling-like fashion – and this seems to be the case for hantavi-ruses [13] – the recombinant...
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