... Chen, Lesmond, and Wei (2004)) and use only the fraction ofthe spread that is likely to be due to default risk Structural models in the tradition of Leland (1994) and Leland and Toft (1996) are ... directly under the risk- neutral measure Others (e.g., Titman and Tsyplakov (2004), and Hennessy and Whited (2005)) assume risk neutrality and discount the costs of financial distress by the risk- free ... sovereign bonds The Risk- Adjusted Cost of Financial Distress 2559 Our estimates suggest that risk- adjusted probabilities of default and, consequently, the risk- adjusted NPV of distress costs,...
... affinity of Fpg for the THF:C ligand was 1.6-fold higher than for the THF:A ligand The presence of Mg2+ had little effect on the binding of Fpg to the THF:C ligand and slightly improved binding to the ... evaluate the effects of ionic strength and Mg2+ on the activity and specificity of OGG1, we measured the apparent values of k2 and k3 under conditions of low salt (KPi only) and no Mg2+, low salt and ... may be affected by ionic strength, the concentration of divalent cations such as Mg2+, the nature ofthe buffering agents, the presence of competing polyamines and other small molecules, and crowding...
... with the first month post initiation and continuing through the end ofthe year The mean cumulative days of hospitalization at the end of each ofthe 12 months post initiation indicated that the ... olanzapine and risperidone treatment groups, respectively), and for the number of days between initiation ofthe index and discharge from the hospital for individuals who were inpatient at the time of ... period of time in which the patient had worsening of symptoms that changed the patient's daily routines and pattern of care seeking Further, in order to address the potential impact of changes in the...
... effects of obesity on theriskof adenocarcinomas ofthe oesophagus and gastro-oesophageal junction, alone and in combination with other causal factors PATIENTS AND METHODS Approval to undertake the ... Ministry of Health and Medical Education of IR Iran andthe National Health and Medical Research Council of Australia, respectively The funding bodies played no role in the design or conduct ofthe ... measure for subsequent analyses BMI andriskof adenocarcinoma ofthe gastro-oesophageal junction Significant trends of increasing riskof adenocarcinoma ofthe gastro-oesophageal junction with...
... considering the effect of various design and operating parameters on theperformanceand thermal characteristics ofthe system Description ofthe multi-stage evacuated solar desalination system The Multi-stage ... outlet of first collector will be inlet to the second collector andthe outlet ofthe second collector will be inlet to the next and so on up to the Ncth collector Thus, the outlet temperature ofthe ... the top ofthe last stage, there is a water tank of 150 liters capacity which stores the saline water The saline water from the tank flows through the combination of flat plate collectors and thus...
... [30] The ionic strength P was calculated using the equation I = ½ ciZi2, where I is the ionic strength ofthe solution, and ci and Zi are the concentration and charge of species i, respectively The ... acid In addi˚ tion to these contacts, there is a 1.82 A contact between Gly255 Ca and Od2 ofthe oxidized cysteine To further understand the structural consequences ofthe P-loop transition that ... bonds with the P-loop main chain and Od1 and Od2 Although there are movements in the P-loop, there are no other major conformational changes in the protein Most notably, the loop containing the general...
... bright and jovial face for the banquet, Macbeth agrees, adding that while the crown is unsafe, they should keep their titles honourable and let their faces mask their evil hearts The theme of 'deceptive ... acting of his own initiative without consulting his Lady In the third scene, the sun is setting and it is getting dark There are now three murderers instead ofthe two that met Macbeth in the first ... here convinces the murderers against Banquo The last speech of Macbeth is in a way similar to the one of Lady Macbeth addressing the evil spirits Lady Macbeth is receding into the background...
... blue) Also shown are the heme ligands (histidine and methionine in each case), the cysteines that form thioether bonds to the heme, andthe methyl group ofthe alanine ofthe C fasciculata AXXCH ... methionine and histidine side chains that coordinate the heme iron, andthe cysteine side chain that forms a thioether bond between heme and protein Also shown is the methyl group ofthe alanine ofthe ... identity and 72% similarity The structures are remarkably similar overall, and in the details ofthe heme attachment and heme position The rmsd between the structure of C fasciculata cytochrome c ˚ and...
... 98/43/EC ofthe European Parliament andofthe Council of July 1998 on the approximation ofthe laws, regulations and administrative provisions ofthe Member States relating to the advertising and ... commands, the law of one sovereign must apply at the expense ofthe law ofthe other, and in the federal or transnational union, if the union and integration—are to be meaningful, it must be the ... regarding the coordination and definition ofthe corresponding spheres of power, which is essential to determining the fields of activity ofthe various levels of government andthe validity and hierarchy...
... upon the horrors ofthe middle passage andthe sufferings ofthe poor negroes as set down in the log-books ofthe slavers, the St John andthe Arms of Amsterdam It is comforting to the more soft-hearted ... stars and set in it a crescent holding a profile ofthe traditional Man in the Moon The panel below bears the arms ofthe City of Amsterdam andthe letters V.O.C forming the monogram ofthe Dutch ... Holland by the ringing of bells, the discharge of artillery, the illumination ofthe houses, andthe singing of hymns of thanksgiving in all the churches The devout people knelt in every cathedral...
... of feeling their voices are worth listening to, that they are part of their community, and that they have achieved an understanding of others andof their own culture —A wish to see their own ... information and material injurious to his or her well-being, bearing in mind the provisions of articles 13 and 18 Article 12 ofthe Convention on the Rights ofthe Child recognizes the right ofthe children ... dreams and their own local, social and ethnic culture and reality portrayed in the media —Strengthened ability and curiosity, and increased media competence, i.e., their critical understanding of the...
... characterize the differences in the permeability ofthe BTB of a malignant brain tumor to that ofthe BTB of a peripheral solid tumor, and to define the upper limit of pore size within the BTB ofthe ... and define the upper limit of pore size within the BTB of brain tumors and peripheral tumors We determined the differences in the permeability ofthe BTB of an ectopic RG-2 glioma and an orthotopic ... compared the permeability ofthe BTB of RG-2 gliomas grown within the brain, the orthotopic site, to that ofthe BTB of RG-2 gliomas grown outside the brain in the temporalis skeletal muscle, the...
... take a slice ofthe TFD T(t, f ) (2) Search and count the number of peaks in each slice (3) Evaluate the histogram ofthe obtained set of peaks numbers (4) Estimate the total number ofthe signal ... of peaks ofthe TFD slice T(t0 , f ) By searching and counting the peaks of each TFD slice, we end up with a set of numbers The number corresponding to the maximum ofthe histogram of these numbers ... order to group the halves (or parts) ofthe actual components together This is performed in the third and last phase ofthe algorithm Algorithm gives the details ofthe second phase The classification...
... being deleted RK: If there is a good chance that the data are going to be used by others, then yes, there is a good case for storing them Just storing the raw data for the sake of it, however, is ... MG: Due to the huge sizeofthe files, uploading and downloading data from a central repository is not easy The model of a central archive may need to be revisited and we may see in the future ... primary object of study, exchange, and archiving PF: As with any archiving project, one needs to con sider the cost of storage relative to the potential future reuse In the course ofthe 1000 Genomes...
... M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial ofthe European Organization ... Role of mitomycin in combination with fluorouracil and radiotherapy, andof salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma ofthe anal canal: results of ... perioperative chemotherapy based on the results ofthe MAGIC trial with epirubicin, cisplatin and 5-FU is frequently used and this approach will continue to be the standard of care even after...
... NH and OB conceived ofthe study, participated in its design, and in drafting the manuscript HT and JB participated in the study design and coordination and in discussing manuscript NH, NBF and ... erroneous results, the limit ofthe rapid methods using classic PCR is the low sensitivity of DNA detection (the limit of detection of our method being 10 copies/ml) This explains that the genotyping ... Ava II and bands 306 pb, 88 pb, 52 pb with Dpn II) Genotype A was detected in 4% ofthe cases with specific RFLP profile of A1 pattern (301 pb, 121 pb, 57 pb with AvaII and 318 pb, 109 pb and 52...
... investigated the effect of charge on the fluxional behavior ofthe Sn9-q (q ) 1-4) clusters into the D3h and C4V isomers The results on the lowest energy structures (within the symmetry constraint) and their ... photon beam to analyze the kinetic energies ofthe photodetached electrons If hv is the energy ofthe photon and e-KE is the measured kinetic energy ofthe emitted electron, the difference (hv - ... have on the relative stability ofthe two isomers? Furthermore, what role the sizes ofthe constituent atoms play as one substitute a larger Bi atom in place of a Sn atom? The purpose of this...
... (1) the SNRs often found in the environment span the range of −10 to dB and should therefore be included in the evaluation of algorithms for hearing aids [17] and (2) the SRT point, at which there ... represents the threshold for determining whether the current dynamic range ofthe signal is low, medium or high The parameter β can take on values between andand is used in comparisons of whether ... section, the speech and noise classification performanceofthe envelopebased VAD for the three settings of β is presented The percentages of correctly detected samples were calculated for the scenarios...
... and compares the results ofthe centrifuge modeling with the numerical analyses The influence ofthe pile installation method is further examined by comparing the findings from the database and ... on the pile dimension andthe nature ofthe sand, but also on the installation method of displacement piles and other factors 2.3 FACTORS AFFECTING PILE END BEARING RESISTANCE 2.3.1 Method of ... which incorporates the state-ofthe-art understanding ofthe underlying controlling mechanisms This Thesis is dedicated to address the factors influencing the end bearing performanceof displacement...