galton watson process model of gene amplification and deamplification
Báo cáo y học: "A dynamic model of gene expression in monocytes reveals differences in immediate/early response genes between adult and neonatal cells" potx
Ngày tải lên :
11/08/2014, 08:21
... standpoint, our data demonstrate how gene microarray experiments can quickly move from the generation of gene lists to the development of plausible and testable models of relevant biology and ... DFA analysis of phases of monocyte activation comparing cord and adult cells DFA analysis of phases of monocyte activation comparing cord and adult cells DFA identified a subset of genes (see Table ... allows identification of the genes within clusters by visual inspection and subsequent functional analysis of genes within clusters (Figures 3A &3B) Figure 3A represents 110 genes of the same cluster...
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Báo cáo y học: " A model of gene-gene and gene-environment interactions and its implications for targeting environmental " doc
Ngày tải lên :
13/08/2014, 16:21
... restricts the model to special cases of gene- gene and gene- environment interaction Note that for a single genetic variant, rg corresponds to the penetrance of the variant, and that in general (provided ... assumptions, although often made, are implausible in many situations The assumption of no confounders means that the model can only represent a subset of the potential models of gene- gene and gene- environment ... Equations (29), (30) and (31) However, in the absence of prior knowledge about the form of the genetic model, the presence or absence of gene- environment interactions, and the validity of the 'equal...
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A model of aesthetic appreciation and aesthetic judgments pptx
Ngày tải lên :
07/03/2014, 17:20
... we present an information-processing model of the aesthetic experience (see Fig 1) The model is based on the above analysis of modern art and describes a number of processing stages that characterise ... and input of the model A work of art is the input for the model Aesthetic experiences often require a pre-classification of an object as art This pre-classification can be assured by a number of ... misattribution and judgments of well-being: Informative and directive functions of affective states Journal of Personality and Social Psychology, 45, 513– 523 Shiff, R (1986) Cezanne and the end of Impressionism:...
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A Dynamic Structural Model of Addiction, Promotions, and Permanent Price Cuts pot
Ngày tải lên :
16/03/2014, 09:20
... expectations of the future distribution of prices (Erdem and Keane 1996, Gonul and Srinivasan 1996, Sun, Neslin, and Srinivasan 2003) A key component of the model is the random process governing ... Hand of the Past,’ and Heterogeneity in Dynamic Brand Choice,” Marketing Science 15(3): 280–299 52 Seetharaman, P B (2004), “Modeling Multiple Sources of State Dependence in Random Utility Models: ... three brands account for 85% of demand Nabisco is the dominant brand with more than 45% of the market and the highest sales-weighted price of $1.95 per 16 ounce box of crackers Keebler and the...
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Báo cáo khoa học: "A Model of Lexical Attraction and Repulsion*" potx
Ngày tải lên :
24/03/2014, 03:21
... both text and conversational speech We presented a training algorithm for this class of distance models based on a novel application of the EM algorithm Using a standard backoff trigram model as ... (We exclude separation of one or two words because of our use of distance models to improve upon trigrams.) The set of 41,263 trigger pairs was partitioned into 20 groups of non-self triggers (s, ... Nonstationary To incorporate triggers and distance models into a long-distance language model, we begin by constructing a standard, static backoff trigram model (Katz, 1987), which we will denote...
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Báo cáo " Moving parabolic approximation model of point clouds and its application " pdf
Ngày tải lên :
28/03/2014, 10:20
... local maps of differential geometry [5] and practical algorithms in optimization theory [6] The main contribution of this work is a scheme to generate a point-based reconstruction of an unorganized ... surface modeling using unorganized data points A powerful approach is the use of the moving least-squares (MLS) technique [2] for modeling point-based surfaces [1] One of the main strengths of MLS ... (n,ζ,a,b,c) are decision variables and ρ is a scale parameter 2.1 MPA model n Suppose that a given set of data points {p j }j =1 is noisy sampling of an underlying surface S Generally, pj will not lie...
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Báo cáo toán học: "The Model of Stochastic Control and Applications" pdf
Ngày tải lên :
06/08/2014, 05:20
... sequence of the exponentially distributed independent random variables with the parameter μn+1 (μn+1 > 0), and νμn+1 (ξn+1 ) is random variable defined by The Model of Stochastic Control and Applications ... optimal cost Defining Control Model 1.1 Constructure of the Model Suppose there exist two sequences of independent random variables {ηn |n = 1, 2, } and {ξn |n = 1, 2, } defined on probability ... {xn |n = 1, 2, } and with control process {un = u(μn )|n = 1, 2, } described as follows: For an initial state of elementary process x1 = x(x ∈ R), at the first step, a sequence of controlling variables...
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Báo cáo lâm nghiệp: "A model of light interception and carbon balance for sweet chestnut coppice (Castanea sativa Mill.)" pdf
Ngày tải lên :
09/08/2014, 04:20
... photosynthesis-light curve (by unit leaf area of the tree) compared with the outputs of the model for a single tree and for two light conditions The light saturation was at 600 pE-m and the maximum -s-1 tree photosynthesis ... half of the maximum photosynthesis Agreement between measurements and model outputs is good However, at low light levels, the model underestimated photosynthesis for overcast sky conditions and ... iform, the model does not account for assimilate partitioning We used it to derive a carbon balance of the stand, computed as the difference between net assimilation (predicted) and (growth and maintenance)...
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Báo cáo y học: "The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanase" docx
Ngày tải lên :
09/08/2014, 06:23
... in situ effect of licofelone on the gene expression and protein synthesis of the major collagenolytic enzymes (MMP-13 and cathepsin K) and aggrecandegrading proteases (ADAMTS-4 and ADAMTS-5) in ... collected and processed with GeneAmp® 5700 SDS software and given as a threshold cycle (Ct) Plasmid DNA containing the target gene sequences was used to generate standard curves A DNA standard curve ... score of 5.1 (3–11) and a safraninO score of (0–4) Specimens from licofelone-treated groups had a Mankin score of 3.5 (0–10) and a safranin-O score of 0.4 (0–3) with the 2.5 mg dosage and a Mankin...
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Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx
Ngày tải lên :
12/08/2014, 17:22
... analysis and interpretation of gait data and also provided technical assistance for the collection of ground reaction forces WJR assisted in the development of the surgical model WJR and LAS assisted ... the conception and design of the experiment and the analysis and interpretation of the data All authors have read and approved the final manuscript Acknowledgments The contributions of Mr Steve ... including the reduction of thermal and mechanical hypersensitivities, and reduction of nerve root edema and inflammation [4, 6, 8, 10, 13, 15] However, a single systemic administration of TNF antagonists...
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Báo cáo y học: "External validation of a modified model of Acute Physiology and Chronic Health Evaluation (APACHE) II for orthotopic liver transplant patients" docx
Ngày tải lên :
12/08/2014, 18:21
... increasing worldwide availability of liver transplantation, a standardized assessment of severity of illness is needed to evaluate patient outcome objectively over time and between different institutions ... in a series of complex interactions that include intra-operative and postoperative factors Systems for predicting the severity of illness and mortality, such as the Acute Physiology and Chronic ... original model 12.96 ± 10.25 12.27 ± 9.60 24.28 ± 4.12 0.001 8.89 ± 8.08 8.37 ± 7.60 17.37 ± 11.14 0.001 Number of patients ROD new model (%) SMR original model; 95% CI 0.44; 0.22–0.80 SMR new model; ...
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Báo cáo y học: " A stochastic model of oncogene expression and the relevance of this model to cancer therapy" ppt
Ngày tải lên :
13/08/2014, 23:20
... ablation of an oncogene's protein activity can result in apoptosis and/ or a decrease in proliferation within a population of tumor cells The goal is then to determine which oncogene or set of oncogenes ... set of transformed states associated with aberrant gene expression, the set of differentiated states that have been defined as a result of stochastic gene expression and the distribution of cells ... cells are also defined by the set of oncogene/suppressor genes that are active within the cell and the number of different cellular mechanisms that this set of genes acts upon to change the cell's...
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Báo cáo y học: " A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum" docx
Ngày tải lên :
14/08/2014, 08:21
... approximately 22 h of (3,639 genes), 3D7 (2,419), of Dd2 of P falciparum strains HB3 the IDC Snapshot of a comparison of the expression slopesandgenes (2,718) at Snapshot of a comparison of the expression ... from afile Forty process. among approximately multigene genes of P falciHB3 down-regulated of 100 in information HB3 3D7, andHB3 genes on gene activities of analysis.falciInternal genes HB3 based ... group of genes belongs to class C5 (Figure 8) This lack of overlap of genes during the first and second round of subtelomeric upregulation leads us to hypothesize that the bias between terminal and...
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Báo cáo y học: " Advances in the genetics and epigenetics of gene regulation and human disease" pps
Ngày tải lên :
14/08/2014, 17:22
... several generations of offspring He and his colleagues postulate that maternal nutrition before and during pregnancy may affect the establishment of CpG methylation and the life-long expression of ... analysis of genes that are involved in cell-cycle control and cell-size regulation in Drosophila Using flow cytometry, Björklund and colleagues analyzed the RNAi-induced loss -of- function of 70% of ... variety of human cancers, and are often associated with poor clinical outcome for the patient Target genes for amplified regions are often oncogenes, which may be used as therapeutic, prognostic and...
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Spinning Process - Model Of Optimum Cotton Mixing
Ngày tải lên :
13/08/2015, 13:23
... line Thickness of the feed web Density of the feed web Fibre micronaire Size of the flocks in the feed Type of clothing of the beater Point density of clothing Type of grid and grid settings ... blending Types of Blending: hand stock blending bin blending lap blending card blending draw frame blending Model of optimum cotton mixing: The program is written on the basis of principles of linear ... room: Number of opening machines Type of beater Type of beating Beater speed Setting between feed roller and beater Production rate of individual machine Production rate of the entire...
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Role of SPHK2S1P signalling in regulating mitochondrial function in the MPTP induced mouse model of parkinsons disease and in the MPP treated MN9D cells
Ngày tải lên :
09/09/2015, 08:12
... completion of my thesis I am extremely thankful and grateful to Professor Charanjit Kaur for her encouragement and moral support throughout my candidature She has been a pillar of strength and a source ... Expression of Sphk2 in the MN9D cells 74 3.11 Expression pattern of Sphk2 in the substantia nigra of the MPTP-induced mouse model of Parkinson’s disease 75 3.12 Gene expression analysis and ... mechanisms of the cell death cascade These key processes have been replicated in experimental models of PD for a better understanding of the underlying molecular mechanisms The discovery of 1-methyl-4-phenyl-1,...
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Development of a realistic finite element model of human head and its applications to head injuries
Ngày tải lên :
10/09/2015, 09:04
... components of a subject-specific model of human skull and brain (Model 1) segmented from CT and MRI data by Mimics The meshed model on the right shows the mid-sagittal view of the skull and CSF ... 103] (A) The skull model; (B) the brain model with 11 pairs of bridging veins; (C) sagittal cross section of the head and neck model; (D) anatomical structures modeled in KTH model ... nodes of the base of the neck of Model 119 Figure 38: Mid-sagittal view of the displacement magnitude (in mm) contour plots of the head-neck model, showing various mode shapes and...
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A hypercube model of ICT (information and communications technology) strategy towards a theory of competency maturity
Ngày tải lên :
11/09/2015, 21:50
... ," Acknowledgments i Summary ii Table of Contents iv List of Tables x List of Figures xi Glossary xii :: : :B :< :; ... C r ea t e of co m m u ni t ies D e st r oy ex ist ing in dust r y s t ruc t u r e I ndust r y Sh a keou t R e jec t ed des i gns D o m i nan t D e sign D om i nant D e s ign/ S tanda Yes rd...
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A generalised lattice boltzmann model of fluid flow and heat transfer with porous media
Ngày tải lên :
16/09/2015, 12:42
... Hardy, Pomeau and Pazzis as HPP (1973) There are some LGCA models discussed in Guo and Zhao (2002d) One of them was the HPP model (Vafai and Tien 1981) with a D2Q4 lattice model HPP model is used ... models can be taken as the limiting generalized model Additionally, the generalized models mentioned above can be used to model transient flow in porous media Since the analytical solutions of ... range of forcing and effective viscosity This model eliminates the second order errors in velocity and improves stability over the SP model It also improves the accuracy of other applications of...
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The role of caspase 1 in a murine model of influenza pneumonitis, and studies on cell death inhibitors in vitro
Ngày tải lên :
13/10/2015, 16:41
... the role of caspase-1 pulmonary inflammation and cell death and its contribution to immunopathology of influenza infection of the lung in an in vivo murine model A detailed understanding of the ... Expression of caspase-1 and growth of virus in influenza A/PR/8/34 (H1N1) infection of RAW264.7 macrophages 130 4.3 Insights into the role of caspase-1 using a murine model of influenza ... infection of RAW264.7 macrophages 65 3.1.6 Evaluation of influenza A infection of RAW264.7 murine macrophages 66 3.2 AN INVESTIGATION OF THE ROLE OF CASPASE-1 IN AN IN VIVO MOUSE MODEL OF INFLUENZA...
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