from clinical data to molecular genetics and return
introduction to molecular genetics and geonomics - hearts
... 09131_01_1677P Photocaptionphotoca ptionphotocaptionphotocaptionphotocaptionphotocaptionp hotocaptionphotocaptionphotocaptionphotocaptionphotocaption photocaptionphotocaptionphotocaptionphotocaptionphotocap ... photocaptionphotocaptionphotocaptionphotocaptionphotocap tionphotocaptionphotocaptionphotocaptionphotocaption 09131_01_1678P 1.8 Evolution from Genes to Genomes, from Proteins to Proteomes 27 genetic information from DNA to RNA to protein makes ... Introduction to Molecular Genetics and Genomics 1.8 Evolution: From Genes to Genomes, from Proteins to Proteomes The pathway for the breakdown and excretion of phenylalanine is by no means unique to human...
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From Patient Data to Medical Knowledge The Principles and Practice of Health Informatics ppt
... diseases to include, which data items to collect, how to perform the calculations and how to present the results They were prepared to the best they could and then to expose the results to empirical ... AAPHelp to generate a prediction, someone had to enter the patient’s symptoms into the computer They had to be collected in a standard format, to match the data stored in the computer In order to ... might be able to listen more constructively to their patients’ stories if they tried to understand them as stories, rather than attempting to express them in the structured and standardised format...
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Practical and laboratory diagnosis of tuberculosis from sputum smear to molecular biology 2015
... laboratory by automated thermal desorption, gas chromatography, and mass spectroscopy (ATD/GC/MS) In order to quantify peak areas and to control for drift in instrument performance, an internal standard ... the spectrum of clinical diagnosis through the microbiological and molecular gold standard, the most practical, due to its celerity and high sensitivity The diagnosis of LTBI, key to TB control, ... method and Löwenstein–Jensen culture has been the main TB diagnostic tool Sputum smear examination is reliable, reproducible, and cost-effective for TB diagnosis and to monitor patient response to...
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Tài liệu COMMUNICATION FROM THE COMMISSION TO THE COUNCIL AND THE EUROPEAN PARLIAMENT Innovation in a knowledge-driven economy ppt
... form, sector or location, are to have the potential to grow and develop so as to contribute to the overall goal To survive in the new competitive environment, no enterprise can afford to stand still ... can afford to stand still All have to be open to new ideas, new ways of working, new tools and equipment, and be able to absorb and benefit from them A policy to enhance innovation must be present ... administrative and regulatory environment is still too complex The complexity of administrative and regulatory procedures continues to be a serious obstacle to the creation of new businesses and to entrepreneurship...
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Tài liệu The ZEN Approach™ to Project Management Working from your Center to Balance Expectations and Performance docx
... organizations and people Special thanks to my editors, Judy Umlas and Ed Levy for their contribution to making this expression clear and useful Thanks and homage to my teachers from several traditions: ... “who am I?” and cut to the core of self Thanks also to Gabriel Halpern who introduced me to Yoga and to the joy of chanting and song as a means for going beyond the intellect Thanks to N.Y Insight ... you wander from the truth 22 \ The Zen Approach™ to Project Management Stop talking and thinking and there is nothing you will not be able to know … Do not search for the truth: only cease to cherish...
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The Gravity of Weight A CLINICAL GUIDE TO Weight Loss and Maintenance pdf
... Weight A CLINICAL GUIDE TO Weight Loss and Maintenance This page intentionally left blank The Gravity of Weight A CLINICAL GUIDE TO Weight Loss and Maintenance Sylvia R Karasu, M.D Clinical Associate ... and Perils of High-Protein Diets and Their Relationship to Low Carbohydrate and High Fat Intake The Advantages and Perils of High-Carbohydrate Diets and Their Relationship to ... Weight: A Clinical Guide to Weight Loss and Maintenance, is our attempt to explain some of these discrepancies and explore particularly why, for most people, it is so difficult to lose weight and maintain...
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from plant data to process control
... order and relative degree The FSF structure was first introduced to the areas of system identification and automatic control by Bitmead and Anderson (1981), Parker and Bitmead (1987) and Middleton ... step toward derivation of empirical rules for the optimal choice of the time scaling factor p is to reduce the number of variables in Equation (2.62) from (a, p and d) to To so, we will choose to ... experimental and/ or application studies are welcome, as are expository texts where theory, verification and applications come together to provide a unifying coverage of a particular topic or topics...
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kumar - molecular genetics and breeding of forest trees (haworth, 2004)
... Vidhyaskdaran Molecular Genetics and Breeding of Forest Trees edited by Sandeep Kumar and Matthias Fladung Testing of Genetically Modified Organisms in Foods edited by Farid E Ahmed Molecular Genetics and ... Introduction The Ectomycorrhizal Symbiosis The Anatomy and Development of Ectomycorrhiza The Morphogenesis of Ectomycorrhiza Alteration in Gene Expression in Ectomycorrhiza The Transcriptome of Ectomycorrhizal ... Cryptomeria and Populus databases were roughly equal Further emphasizing the differences between the Populus and Cryptomeria cambial tissue databases, no ESTs are found in the Cryptomeria database...
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A Guide to Molecular Mechanics and Quantum Chemical Calculations
... are made up of atoms and bonds (as opposed to nuclei and electrons), and atom positions are adjusted to best match known structural data (bond lengths and angles), as well as to accommodate non-bonded ... Chapter 4, and connections drawn between electron density and both chemical bonding and overall molecular size and shape It is straightforward to generalize the Schrödinger equation to a multinuclear, ... confronted with “too many choices” to make, and “too few guidelines” on which to base these choices The fundamental problem is, of course, that the mathematical equations which arise from the application...
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báo cáo sinh học:" From staff-mix to skill-mix and beyond: towards a systemic approach to health workforce management" ppt
... developing tools that will enable managers to clarify the roles of their staff in different contexts, to monitor the scopes of practice of their staff, and to detect any barrier or facilitator to effective ... management tools that divert focus away from the issue of numbers and occupational mix towards the range of roles, functions, responsibilities and activities each staff member is educated and able to ... staff-mix modifications to address organisational and system factors To support planner, policy makers and workforce planners, this article reviews the main approaches to and limitations of conventional...
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Báo cáo y học: " ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic region" doc
... statistical framework used is applicable to both high signal -to- noise data such as from CTCF ChIP-seq, as well as to low signal -to- noise data such as from FAIRE-seq ZINBA produces peak calls ... 0.50) from the (c) RNA Pol II and (d) FAIRE data Median regression lines fit to the set of background windows from each dataset parallel the ZINBA-estimated relationships between G/C content and ... data exhibit punctate, high signal -to- noise ratio peaks, FAIRE-seq data have broader, low signal -to- noise ratio peaks, and RNA Pol II ChIP-seq data contain a mixture of punctate high signal -to- noise...
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A clinical guide to stem cell and bone marrow transplantation - part 1 pps
... husbands Daniel, Dan, and Keith, and our children Alexandra, Derek, and Leah, who lent support and sanity in our times of need we love you! Page vi Preface As the science and technology of clinical ... transplant experience to good use, and thus, this handbook was developed The concept of this handbook also arose as a result of multiple pleas for a comprehensive "nuts and bolts" guide from colleagues ... Davison Ambulatory management following bone marrow transplant (BMT) 411 411 Page i A Clinical Guide to Stem Cell and Bone Marrow Transplantation Page Introduction to Stem Cell and Bone Marrow...
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A clinical guide to stem cell and bone marrow transplantation - part 2 potx
... GVHD risk factors) C Medical evaluation Complete medical history Attention to chronic medical problems Medications Pregnancy history (female) Anesthesia history Transfusion history History of blood ... found to be the dose-limiting toxicity In dose escalation studies of etoposide combined with 12- or 13.2-Gy fractionated TBI, 60 mg/kg of etoposide was found to be the maximum tolerated dose; stomatitis ... origin, gram-positive and gram-negative septicemia, and bronchopulmonary infection History and physical examination a) A careful history should be taken to search for symptoms suggestive of infection...
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A clinical guide to stem cell and bone marrow transplantation - part 3 pps
... Practice, and Nursing Insights Boston: Jones and Bartlett; 1991 Szer J Cryopreservation and functional assessment of harvested autologous bone marrow and blood stem cells In: Atkinson K, ed Clinical ... blood cells (PRBCs) and platelets to reduce exposure to HLA and cytomegalovirus (CMV) Give CMVnegative products to CMV-negative patients, since the virus is carried on granulocytes and may increase ... flora Discourage visitors from bringing coats, or purses into the patient's room Reprinted with permission from Ezzone and Camp-Sorrell, 1994 Page 87 B Isolation: Filtered air to 0.3 µm is indicated...
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A clinical guide to stem cell and bone marrow transplantation - part 4 docx
... Mycoplasma, and Legionella e) Gastrointestinal: stool for CMV antigen and culture Stool should always be sent for ova and parasites and C difficile toxin with any diarrheal Page 171 illness Stool for ... are excessive Page 144 e) Stool electrolyte and osmotic gap: Stool osmotic gap formula = 290 - X ([Na] X [K]) Secretory diarrheas tend to have elevated stool [Na] and a resultant lower osmotic ... viral illness and conditioning-related toxicity, the stool tends to have decreased [Na] and increased stool osmotic gap (> 100 mOsm/L) f) Gastrointestinal endoscopy with culture and biopsy (rule...
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A clinical guide to stem cell and bone marrow transplantation - part 5 pps
... histology) and state II–IV clinical liver and/ or gut GVHD Only one system stage III or greater IV Stage II–IV clinical skin GVHD (with > grade histology) and II–III clinical liver and/ or gut ... syndrome) and bladder involvement (severe cystitis) r) Hematopoietic system: Eosinophilia and thrombocytopenia, platelet-bound autoantibodies, autoimmune hemolytic anemia, and reduced hematopoietic ... Clinical Grade Grade Description Stage I clinical skin GVHD (with grade histology) I Stage II clinical skin GVHD (with ³ grade histology) II Stage II–III clinical skin GVHD (with ³ grade histology)...
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A clinical guide to stem cell and bone marrow transplantation - part 7 ppsx
... malabsorption d) Stool electrolytes: Secretory diarrhea tends to have an elevated stool sodium and a lower osmotic gap (< 100 mOsm/L) In malabsorption or viral illness, the stool tends to have a decreased ... required to change position during the scanning procedure Breathing may need to be controlled during the imaging Examination time is usually 30 to 60 minutes VII Cytogenetics A Definition: Cytogenetics ... peripheral blood return to normal rapidly after transplant The monocyte antigen activity returns to normal when the monocyte level returns to normal Diagnostic study: WBCs, with differential to include...
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A clinical guide to stem cell and bone marrow transplantation - part 8 docx
... administration and and h after each dose (refer to individual protocol) Class uroprotectant Dose and route Special considerations Cyclophosphamide: 20% to 100% w/w of dose prior to administration and 3, ... asthenia (Paraplatin) BMT dose; 1500–2000 Dose-limiting toxicity: peripheral neuropathy, mg/m2 (consult protocol) hepatotoxicity, nephrotoxicity,ototoxicity Class: alkylating agent Carmustine (BCNU) ... BMT dose: 150–240 Dose-limiting toxicity: nephrotoxicity, ototoxic mg/m2 (consult protocol) Cyclophosphamide Tab 25, 50 mg Conventional dose: 500–1500 mg/m (Cytoxan) Injection: 500 mg BMT dose:...
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A clinical guide to stem cell and bone marrow transplantation - part 9 docx
... including likes and dislikes and any faith-based dietary practices Lactose intolerance: Identify any preexisting symptoms with ingestion of lactosecontaining foods and beverages and whether lactose therapy ... The Cancer Chemotherapy Handbook St Louis: Mosby; 1993 Gambertoglio JG Drag use in renal disease In: Knoben JE, Anderson PO, eds Handbook of Clinical Drug Data Hamilton, Ill: Drug Intelligence ... 400 mg on day and 200 mg for weeks for systemic Candida Fluconazole, 200 mg on day and 100 mg for weeks for esophageal Candida L In the BMT setting, HSV, cytomegalovirus (CMV), and VZV can be...
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A clinical guide to stem cell and bone marrow transplantation - part 10 ppt
... and familiy to ask you questions c) Generally, most patients and families want to know if death will be painful or slow and how they will know when it is happening d) From a psychological standpoint, ... it is taboo to miss birthdays, anniversaries, and greetings, it is not to avoid saying goodbye, finally, to loved ones Social taboo and general discomfort on the pan of the staff and family often ... GVHD, 99-101, 195 monitoring of, 369 neurologic complications with, 239 Cytarabine, 238, 348t Cytogenetics, 274-76 Cytokine(s), 119, 195 Cytomegalovirus immune globulin, 358t Cytomegalovirus (CMV)...
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