foundations in cancer research chromosomes and cancer the evolution of an idea
Advances in Relationship Marketing Thought and Practice: The Influence of Social Network Theory
... weak ties in situational conversation (Reingen and Kernan 1986; Brown and Reingen 1987) • Individual influence in the buying systems in a B2B context (Ronchetto, Hutt and Reingen 1989) The Socio-Economic ... in cross channel use – 54% of Gen Yers research online and buy offline – Gen Xers also are more likely to have researched and purchased a product online – Gen Xers also dominate online shopping ... (Balasubramanian and Mahajan 2001; Devaraj, Porter and Sun 2006; Dholakia et al 2004; Kozinets 2002; Muniz and O’Ginn 2001; Porter and Donthu 2004; Schouten and Koenig 2002) Questions for future research...
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Báo cáo y học: "α The role of HIF-1α in maintaining cartilage homeostasis and during the pathogenesis of osteoarthritis" pot
... role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival During hypoxic and normoxic conditions, functional inactivation of HIF-1α in the presence of interleukin-1β ... resulted in a significantly increased number of apoptotic chondrocytes These in vitro data are in accordance with the in vivo observations described by Schipani and colleagues [15] Loss of HIF-1α in ... that HIF-1 is of pivotal importance in cartilage development and homeostasis Furthermore, given the decreased oxygen levels and presence of inflammatory mediators during the course of OA, a causal...
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Báo cáo y học: "Age-specific mortality patterns in Central Mozambique during and after the end of the Civil War" ppt
... Mozambique Int J Epi 1996, 25(2):349-356 Page of 13 Coninx R, Dupuy C: Effects of the civil war in Central Mozambique and evaluation of the intervention of the International Committee of the Red ... outside Beira) and absence of a father This indicates that women may have been searching for sanctuary in Beira while men were either fighting or working in neighboring countries So, agreeing with ... returning which could have helped explain some of the patterns observed in the late 1990s-early 2000s Even including the other causes among the 24-49 year olds in Beira, HIV/AIDS was the main cause...
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the united nations security council and war the evolution of thought and practice since 1945 aug 2008
... regard being specially paid, in the Wrst instance to the contribution of Members of the United Nations to the maintenance of international peace and security and to the other purposes of the Organization, ... been the mixture of UN and extra-UN activity, with the UN regularly laying down the guiding principles, helping keep the parties to them, and then acting as the rallying-point in gathering political ... Council and the state leading the coalition about the continuation and interpretation of an earlier mandate to use force This problem arose in the Korean War in 1950–3, and was also at the centre of...
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Tài liệu Psychotherapy and Survival in Cancer: The Conflict Between Hope and Evidence pptx
... description of the statistical methods used, detailing of the flow of participants through the study and their baseline characteristics, and an interpretation of the results as they fit in the context of ... content of the interventions, the statistical analytic decisions, and the dates of recruitment and follow-up, and they addressed their findings in the context of the literature Primary weaknesses included ... regarding the intervention itself, the statistical analyses performed, and the methodology and adequate discussion of the generalizability of the results and how they fit in the context of existing...
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Báo cáo khoa học: Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73c in lung cancer doc
... alternative splicing in the 3¢-end (leading to the formation of a, b, c, d, e, f and g isoforms) [8–12]; (b) the use of an extrinsic promoter (P1) and an alternative, intrinsic promoter (P2) in the 5¢-end ... lung cancer cell lines (HTB59, HTB58, and SKMES1), in the adenocarcinoma cell lines (CALU3, CRL5935, A549, and SKLU1), and in the large cell lung cancer cell line (CORL23) In agreement with the ... noted in the anaplastic carcinoma cell line (Fig 2C, lane 3), and the levels of the complexes appeared to remain equivalently high in the small cell lung cancer cell line (Fig 2C, lane 4), the...
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Báo cáo khoa học: "The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques" ppt
... read and approved the final manuscript JV, JRo and AF prepared the design of the manuscript; SV made the treatment planning and selected the patients; MS managed the experimental schedule and ... toxicity and the percentage of the urinary bladder receiving 50 Gy, and the association of late GU toxicity with the percentage of the urinary bladder receiving 40 Gy Both types of urinary toxicities ... occurrence and evolution of acute and late GI and GU toxicities and the treatment related characteristics in patients entering our hospital Important findings include: (i) a higher proportion of acute...
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Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx
... Dehydroepiandrosterone inhibits the proliferation of HUVEC by enhancing the expression of p53 and p21, restricting the phosphorylation of RB, and is androgen- and estrogen-receptor independent ... can induce early and late apoptosis and also necrosis Discussion DHEA is an intermediate in the biosynthesis of androgen and estrogen hormones It was originally isolated from the adrenal gland, ... presence and risk of development of cancer Oral administration of DHEA to mice inhibits spontaneous breast cancer and chemically induced tumors of the lung and colon [7]; however, its effect in cervical...
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Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot
... the autoimmune process On the basis of the previous finding of a differential impact of Th1 and Th2 cells on the function of bone marrow-derived DCs (BMDCs), transcriptional changes induced in ... described the effect of angiogenesis blockade in murine CIA Angiogenesis represents an attractive target for therapy in RA, in that increased synovial vessel density is a feature of RA and several angiogenic ... disease the group has made crosses between susceptible and resistant rat strains Several loci that control the onset of arthritis, the severity and chronicity of the disease, and autoantibody...
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Báo cáo y học: "Unfolded protein response in cancer: the Physician’s perspective" pot
... toxicity-free Of particular importance is the lack of understanding of the fundamental roles and mechanisms of protein quality control in development, organ function, the evolution and fitness of organism ... cells and normal cells offers an advantage for the agents that target the UPR to achieve the specificity in cancer therapy The therapeutic potential of targeting the UPR components in cancer mainly ... important mechanism required for cancer cells to maintain malignancy and therapy resistance Identifying the UPR components that are activated or suppressed in malignancy and exploring cancer therapeutic...
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Báo cáo y học: "A critical review of the research literature on Six Sigma, Lean and StuderGroup''''s Hardwiring Excellence in the United States: the need to demonstrate and communicate the effectiveness of transformation strategies in healthcare" pdf
... training and leadership behavior modeling to bring about significant cultural change and quality and financial gains In contrast to the number of transformational strategies originating in manufacturing, ... than the other Six Sigma studies in terms of external validity In spite of this strength, they still both share many of the same limitations and concerns, as noted above In the case of the hand ... transforming inputs into outcomes) of an organization Adopting and routinizing innovations capable of generating fundamental organization-wide change in practices is a necessary condition of...
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báo cáo khoa học: " A critical review of the research literature on Six Sigma, Lean and StuderGroup''''s Hardwiring Excellence in the United States: the need to demonstrate and communicate the effectiveness of transformation strategies in healthcare" pot
... training and leadership behavior modeling to bring about significant cultural change and quality and financial gains In contrast to the number of transformational strategies originating in manufacturing, ... than the other Six Sigma studies in terms of external validity In spite of this strength, they still both share many of the same limitations and concerns, as noted above In the case of the hand ... transforming inputs into outcomes) of an organization Adopting and routinizing innovations capable of generating fundamental organization-wide change in practices is a necessary condition of...
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Foreign direct investment in Vietnam: An overview and analysis the determinants of spatial distribution across provinces
... trend of FDI into Vietnam First, within the manufacturing, while during the early part of 1990s, the majority of FDI inflows were in oil and mining sector, by the end of the last century and early ... to the fact that Hanoi and Ho Chi Minh city are the two main economic hubs of the country The concentration of FDI in Hanoi and Ho Chi Minh has been attributed to the increased cost of living and ... and modified again to acknowledge the right of foreign investors to merger and acquire companies and branches, and the right to transfer the form of investment Most recently the Unified Law of...
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(1) how learners approach learning, both in and out of classrooms, and (2) the kinds of strategies and cognitive processing they use in second language acquisition
... in two scales of the inventory namely: students’ perceived use of all their mental processes and their satisfaction in their organizing and evaluating their learning of the Foreign Language The ... strategies Advance organization Previewing the main ideas and concepts of the material to be learned, often by skimming the text for the organizing principles Advance preparation Rehearsing the language ... department basing on their good scores in their entrance exam to university, their results of the language proficiency test and their IQ test at the beginning of the school year The group of student...
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Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx
... (given in kb) was determined by kHindIII Size of the bands observed in each autoradiogram is indicated at the right side The 6.6 kb band detected in lanes b, c, and d in autoradiogram (B), and lanes ... enhancing activity, as determined by transient transfection, was associated with DHSs in the Na channel gene and in the first intron of the Ig-b gene Furthermore, the acetylation status of H3 and ... determine the roles of these DHSs on the transcription of Ig-b gene and on the maintenance of the active chromatin state Results Generation of DT40/Cre cells with a long deletion in one allele of the...
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Tài liệu Báo cáo khoa học: cN-crystallin and the evolution of the bc-crystallin superfamily in vertebrates pdf
... All use of animals complied with the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research and the Intramural Animal Care and Use program of the National Institutes of Health ... other mammals A change in the ancient role of cN may be one part of a suite of molecular adaptations in the eye in the human lineage In addition to the evolution of cN and cS crystallins, even more ... relative to cS, the protein has insertions (mainly of glycines), in the c–d loops of motifs I and III and in the connection between motifs III and IV (Fig 1) This protein was given the name cN,...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf
... EMSA analysis of the function of Octamer motif in the fgl2 promoter Lanes 2–5 of panel A and lanes 2–5 of panel B, NE were incubated with labelled consensus Oct-1 Lanes 6–12 of panel A and lanes ... probe are indicated in the top of the panel Supershift, ss-Sp1 and ss-Sp3, were shown in presence of anti-Sp1 and anti-Sp3 Ig Cold and mutated competitors are indicated at the top of the figure ... endothelial cells were incubated with probes shown in Table and Fig Arrows indicate the bands that are interacting with these probes All the lanes have labelled probes The adding of extracts and...
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Tìm thêm: khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25