food poisoning is caused by bacteria only
Báo cáo y học: "Spontaneous Hemoperitoneum Caused By a Diverticulum of the Sigmoid Colon"
Ngày tải lên :
25/10/2012, 10:51
... identifying patients at risk for complicated diverticular
disease. Dis Colon Rectum. 1991;34:339-42.
4. Kourtesis GJ, Williams RA, Wilson SE. Surgical options in acute
diverticulitis: value of sigmoid ...
Schumpelick V. Increased distribution of collagen type III and
reduced expression of matrix metalloproteinase 1 in patients
with diverticular disease. Int J Colorectal Dis. 2001;16:271-5.
3. ... (arrow).
Discussion
The prevalence of diverticulum in patients aged
65 years or more is as high as 65%, but merely 5% in
those below 40 years of age [6].
Sigmoid colon diverticulum is closely...
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KRONE - What is Patch by Exception
Ngày tải lên :
26/10/2013, 19:15
... connectivity company is introducing
"Patch by Exception", the next generation in cable management systems.
Patch by Exception guarantees network managers a system that is not only flexible, ... even easier.
HOW TO GET THE MOST OUT OF PATCH BY EXCEPTION
Many organisations have successfully implemented the Patch by Exception solution by establishing a
maintenance contract with an installer ... changes without the need for assistance from an
installer.
To date this has been achieved by assigning a hub port and an extension port to each individual within an
organisation. If an individual...
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Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf
Ngày tải lên :
15/02/2014, 01:20
... the tissues
producing it. In response to tissue injury, such as
hepatic and renal injury, the inactive single-chain HGF
is converted to a two-chain form exclusively in
the injured tissue. This ... exclusively in
the injured tissue. This conversion is mediated by ser-
ine protease activity, which is induced in the injured
tissue [28]. The two-chain form is required for the bio-
logical activity ... TMPRSS13.
Proteolytic activation of pro-HGF by TMPRSS13
Pro-HGF is proteolytically activated by matriptase
and hepsin, and the protease activity is inhibited by
HAI-1 [9,10,18]. Therefore, we examined...
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Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx
Ngày tải lên :
16/02/2014, 09:20
... investigations that include
analysis of pancreatic islet cells.
The H-PGDS TG mouse is a novel obesity model
with which to investigate the mechanism of adipogene-
sis. As is the case for obese people ... et al. (2001) The mechanisms by which both
heterozygous peroxisome proliferator-activated receptor
gamma (PPARgamma) deficiency and PPARgamma
agonist improve insulin resistance. J Biol Chem 276,
41245–41254.
38 ... molecular mecha-
nisms underlying adipogenesis may lead to the devel-
opment of strategies for reducing the prevalence of
obesity.
Adipogenesis is a complex process accompanied by
various changes...
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Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
Ngày tải lên :
18/02/2014, 04:20
... followed by Strep-tag II
was isolated by BamHI digestion and inserted into the
BamHI site of pmGFP–calpain 7.
To construct pCMV3xFLAG–IST1 and pGEX–IST1, an
IST1 cDNA fragment was amplified by PCR, ... autolysis. Therefore, it is premature
to draw conclusions regarding the mechanism of the
enhancing effects of IST1 on mGFP–calpain 7–Strep
autolysis in vitro.
Both mGFP–calpain 7 and IST1 have ... FLAG–IST1 did not
enhance the autolysis of mGFP–calpain 7 in cultured
cells. On the other hand, overexpression of FLAG–
IST1
DMIM1,2
suppressed the autolysis. This observation
might be explained by...
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Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
Ngày tải lên :
18/02/2014, 12:20
... K
m
values is exclu-
sively displayed by the tetramer forms, and low-
efficiency kinetics with high K
m
values is displayed by
the dimer forms. These observations strengthen the
previous hypothesis that ... K
m
is the Michaelis
constant and K
0.5
is the substrate concentration where
v = 0.5 V
max
. When n = 1, there is no co-operativity, and
K
0.5
= K
m
.
Acknowledgements
This work was supported by ... behaviour after dilution to 6 lgÆmL
)1
indicate that
dissociation of the tetramer to the dimer is a slowly
progressing process. This is supported by the kinetic
behaviour of the recombinant enzyme...
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Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx
Ngày tải lên :
18/02/2014, 13:20
... was
detected using MUPP1 antibodies.
Immunohistochemistry
Mice were raised and maintained according to governmen-
tal and institutional care instructions. Immunohistochemis-
try was carried out on 14 lm ... different odorant molecules is governed by the diverse array of
olfactory receptors expressed by olfactory sensory neurons in the nasal
epithelium. Olfactory receptors consist of seven transmembrane ... between
MUPP1 and OR2AG1 is inhibited by over-expressing
the interacting PDZ domains, the resulting response of
OR2AG1 to odorant is modified in that the rapid
decay of signal is impaired.
We finally...
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Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx
Ngày tải lên :
18/02/2014, 18:20
... cancer. The activity of cyclin dependent
kinase 4 is controlled by multiple mechanisms, including phosphorylation
of tyrosine 17. This site is equivalent to tyrosine 15 of cyclin dependent
kinase ... in HeLa lysates. C-YES
is a 62 kDa nonreceptor tyrosine kinase of the Src
family that is expressed in a wide range of tissues [24].
The N-terminus of C-YES is dually myristoylated and
palmitoylated ... thyroid epithelial cells: activation by TSH, inhi-
bition by TGFbeta, and phosphorylations of its
subunits demonstrated by two-dimensional gel electro-
phoresis. Exp Cell Res 291, 135–149.
35 Sexl...
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Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc
Ngày tải lên :
19/02/2014, 00:20
... aureus is a major food- borne pathogen
which produces a number of toxins and virulence fac-
tors [1]. The staphylococcal enterotoxins produced by
S. aureus are known to cause staphylococcal food
poisoning, ... cytokine synthesis
and febrile response induced by SEC1 is dependent on
NADPH oxidase and not on PI3K ⁄ Akt or 5-LOX ⁄
FLAP because these phenomena are attenuated by
apocynin and not by ETYA, MK ... and
IL-6 that is blocked by the NF-jB inhibitor (PDTC or
SN-50). Moreover, the NF-jB binding ability is abro-
gated by binding site competition and antibody super-
shift analysis. These findings...
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Tài liệu Báo cáo khoa học: Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase pdf
Ngày tải lên :
19/02/2014, 06:20
... precipitated DNA was analyzed by 1% agarose gel electro-
phoresis. DNA was visualized by staining with ethidium bromide. Results are represented by negative images. Asterisks indicate nucleic
acids ... and were isolated as a single peak fraction by
a 0.1–1.0 m NaCl linear gradient in R buffer. Histone H1,
which exists in the DNA affinity fraction, was separated as
a major component stepwise elution ... nuclear foci
linked to phosphorylated histone H2AX (c-H2AX) [3],
which is responsible for the redistribution of repair
factors to DSB sites [4], although it is dispensable
for initial damage recognition...
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Tài liệu Báo cáo khoa học: Transcription of individual tRNA1Gly genes from within a multigene family is regulated by transcription factor TFIIIB pdf
Ngày tải lên :
20/02/2014, 02:21
... multigene
family is modulated by distal cis elements. J Biol Chem
271, 28146–28153.
24 Sharma S & Gopinathan KP (1996) Role of TATATAA
element in the regulation of tRNA
Gly
1
gene expression in
Bombyx ... examined by including heparin (20 lgÆmL
)1
) in the binding reaction (lanes 5,
6, both panels). The complex formation was analysed by electrophoresis on 4% polyacylamide (nondenaturing) gels and visualized ... as marked. The heparin-resistant complex on tRNA
Gly
1
-1 (left) is marked by an arrow; ++ denotes 6 lg of protein. (B) The
specificity of complex formation was examined by the competition with...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf
Ngày tải lên :
20/02/2014, 11:20
... this gene is controlled by Ets-1 and requires the
presence both of the Sp1 and Sp3 transcription factors. The
presence of this complex multicomponent PRD in the fgl2
proximal promoter is consistent ... pre-
sented in this study suggest that this PRD is necessary for
the inducible expression of fgl2, we plan to undertake
additional studies aimed at more precisely elucidating
specific mechanisms regulating ... [2,3], glomerulonephritis [4,5], septic shock [6,7],
and bacterial and viral infections [8]. For example, tissue
factor (TF) [9], the transmembrane receptor of factor VII, is
the major procoagulant...
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Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
Ngày tải lên :
21/02/2014, 01:21
... SODs is not governed by
one or even two residues, but is most likely accomplished by
the concerted effects of a combination of key residues.
Further analysis of these and other mutant SODs is
currently ... electrophoresis (PAGE)
Native 8% polyacrylamide gels (acrylamide : N,N¢-methyl-
enebisacrylamide, 29 : 1, w/w) containing NaCl/Tris,
pH 8.8 utilized a Tris/glycine electrophoresis buffer system
consisting ... N-terminal amino
acid residues. SOD is released from GST-SOD fusion
proteins by cleavage with FXa (Fig. 2C). Although this
method is less efficient than cleavage by thrombin [24] the
released SOD...
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Tài liệu Báo cáo Y học: The binding of lamin B receptor to chromatin is regulated by phosphorylation in the RS region ppt
Ngày tải lên :
22/02/2014, 04:20
... semiquantitatively by t his method. The effects of
enzymes, inhibitors and other reagents on the cell cycle–
dependent interaction could also be examined very easily by
means of t his method. This method is ... meiotic division until they meet sperm. In that
phase, the nuclear envelope is dispersed in the cytop lasm as
nuclear envelope precursor vesicles. Cell cycle progression is
triggered by fertilization, ... shown by sperm chromatin
in vitro ([6,13]; this study), and by mitotic phase chromo-
somes f rom C HO cells [5]. Regulation of the binding of
LBR to chromatin by phosphorylation was shown in this
study...
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