... of Ca2+ channels, either localized in the membranes of intracellular Ca2+ stores or in the plasma membrane Such Ca2+ entry channels in the plasma membrane and Ca2+ release channels in intracellular ... skeletal and cardiac muscle, neuronal and neuronal-related cells, hemopoietic cells, acinar cells, and oocytes (for a more complete list see [15]) Because the cADPR ⁄ Ca2+ signalling system was also ... that cADPR, in addition to Ca2+ release, also promotes Ca2+ entry What are the underlying mechanisms? A mechanism generally assumed to play a role in nonexcitable cells is the capacitative Ca2+...
... homosexuality and relationships have no place in an academic institution Issues such as avoiding sexual abuse and awareness of The Canadian Journal of Human Sexuality, Vol 11 (1) Spring 2002 Table ... rural Ontario (McKay et al., 1998) and 95% in rural Nova Scotia (Langille et al., 1996), and suggests that the fears teachers and administrators have of parental and community opposition may ... dreams, birth control methods and safer sex practices, sexuality in the media, masturbation, sex as part of a loving relationship, attraction, love, and intimacy, homosexuality, sexual behaviour,...
... and antihypertensive medication are highly correlated A detailed analysis of antihypertensive medication indicates that BBL medication and not any other antihypertensive medication is associated ... medication showed that both BBL and other antihypertensive medication, as for example ACE inhibitors, angiotensin antagonists, diuretics or calcium antagonist, are associated with reduced FEV1 and ... lifestyle and health related factors, medical history and respiratory symptoms were performed Cardiovascular (heart attack, stroke) and pulmonary diseases (asthma, chronic bronchitis) were based on self-reported...
... Reservoir area Watershed area Reservoir length Average depth Water capacity Effective capacity Yearly average inflow, outflow Hydraulic residence time Urban area in drainage basin Paddy area in drainage ... season All data Upper layer Wet season Dry season Middle layer Wet season Dry season Bottom layer Wet season Dry season All data at Jannge site Wet season Dry season All data at Jannge site Wet season ... lower layer was similar As a result, condition of both DOC and UVA254 at middle and bottom layer was almost homogenous and the extent of NOM in wet season was about times greater than that in...
... Analytical enzymes and enzyme substrates were specied in previous papers [1518] All other chemicals were of reagent grade and obtained from Sigma and Fluka Preparation of apo-Cc StP and apo-Ec MalP ... recovered activity to Eqn (4) and are summarized in Table They reveal marked decreases in the apparent afnities of the R23 4A and R24 2A mutants for phosphate, compared to wild-type DEA ẳ DEAmax ẵPi ... details of the fractionation Fractions are labeled according to Fig KmG6 and KiG6 were obtained from nonlinear ts to Eqn (2) of the initial rate data recorded at a constant saturating concentration...
... Pf5 ATCC BAA-477 Actinobacteria, Actinobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, Alphaproteobacteria Proteobacteria, ... Proteobacteria, Alphaproteobacteria Proteobacteria, Betaproteobacteria Proteobacteria, Betaproteobacteria Proteobacteria, Gammaproteobacteria Proteobacteria, Gammaproteobacteria Proteobacteria, Gammaproteobacteria ... characteristics of transthyretins and TLPs are indicated above the alignment: motifs A –C’ are indicated with straight lines and are labelled; b-strands are indicated with arrows and are labelled...
... to cause disease These mutations are associate with early onset of the disease and has the pathology includes LBs and is autosomal dominant [21] a- synuclein a- synuclein is a small (14 kDa), highly ... to the parkinsonian neurotoxin MPTP Proc Natl Acad Sci USA 99, 14524–14529 43 Chandra S, Fornai F, Kwon HB, Yazdani U, Atasoy D, Liu X, Hammer RE, Battaglia G, German DC, Castillo PE et al (2004) ... oxidation and nitration can also increase the rate of conversion [76] Binding of polyanions to the C-terminal domain can also catalyse protein aggregation [58] Current research has suggested that...
... systems and procedures, to analyse the organisational structures with a critical mind, and to evaluate the adequacy of the methods and resources, in relation to the assignment; and • a management audit ... internal audit In this regard, the survey inquired about the way internal audit departments are organised, particularly for larger international banks and for banks that are part of financial conglomerates ... mentioned are financial audit, compliance audit, operational audit and management audit.4 Management audits are performed less frequently than the other types of audits 37 Banks report that their audit...
... b-sandwich, a core (which contains a transamidation site anda Ca2+-binding site, and has a helices and b sheets in equal amounts), and two C-terminal b-barrel domains It has been suggested that glutamyl ... the coagulating gland [129] FXIII Coagulation FXIII is a plasma TG, and circulates in blood as a heterotetramer consisting of two catalytic A (XIIIA) and two noncatalytic B (XIIIB) subunits Table ... Esposito and I Caputo 132 Akagi A, Tajima S, Ishibashi A, Matsubara Y, Takehana M, Kobayashi S & Yamaguchi, N (2002) Type XVI collagen is expressed in factor XIIIa+ monocyte-derived dermal dendrocytes...
... around 222 nm (Fig 3A) indicates a random-coil structure In methanol, two positive maxima were observed at 209 and 230 nm (Fig 3A) These two maxima are characteristic of a parallel right-handed ... long-range NOEs observed can be ascribed to two types: those between aHi and NHi+6 (i ¼ 1, 3, and for chain A, and 1, 3, 5, 7, and for chain B); and those between aHi and NHi-6 (i ¼ 10 and for chain ... the standard library of dyana In the 3–Cs+ complex, chains Aand B are connected head-to-head by succinic acid, in such a way that the molecule entity starts from a C-terminus and ends at another...
... insulin pharmacophore, IleA2-ValA3 at the A- chain N-terminus, TyrA19 at the A- chain C-terminus, and ValB12 and TyrB16 at the B-chain central helix assume essentially the same spatial arrangements ... residues at the A- chain N-terminus (GlyA1–IleA2–Val1 3A) [24,25], the A- chain C-terminus (TyrA19 and AsnA21) [26], the B-chain central helix (ValB12 and TyrB16) [27], and the B-chain C-terminal b strand ... PCR strategy using the azuki bean and mung bean genomic DNAs as templates and the synthetic primers legF1 (5¢-AGC AGCAGATTGTAATGGTG-3¢) and legR1 (5¢-CAGC ACTTCAGAATCAGAGTC-3¢) PCR products were...
... Table 3: Mean item-total correlation and Cronbach's alpha for domain scores in the NFAS-4 and the NFAS-5 (N = 3325) Cronbach's alphaa NFAS-4 NFAS-5 Mean item-total correlation NFAS-4 NFAS-5 Walking/standing ... data quality and the thorough testing of validity against other standards The moderate response rate and that all data is self-reported, represent study limitations An external, unrelated variable ... Table 2: Missing data, means and end effects for NFAS-4 and NFAS-5 items (N = 3325) Missing % NFAS-4 NFAS-5 Walking/standing Standing Walking less than a kilometre on flat ground Walking than...
... to moderate physical activity; symptoms suggesting asthma or allergy, the use of medication for asthma or allergy, and the presence of hay-fever and nasal allergies Asthma was defined as answering ... questionnaires and spirometry Forced vital capacity (FVC) and Forced expiratory volume in one second (FEV1) are currently the best available functional measures and predictors of respiratory (and ... spirometry and bronchial reactivity to histamine and constructed the database TN and PH did the statistical analysis On the basis of both PD20 and the AUC method for expressing bronchial responsiveness,...
... Department of Mathematics and Statistics, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia 2Center for Advanced Mathematics and Physics, National University of Science and Technology ... H-12, Islamabad, Pakistan Authors’ contributions All authors contributed equally to the manuscript and read and approved the final draft Competing interests The authors declare that they have no ... eFD functions had been put forward as possible candidates for the anyon function as they interpolate very naturally between the BE and FD functions The above connections enable us to obtain an asymptotic...
... matching can be easily achieved without dramatically increasing unit capacitance Based on behavioral-level simulations, the minimum allowable capacitance value was chosen Six-phase clock signals ... substrate as the digital core, digital circuit noise coupling through the substrate and supply rails was carefully considered as an important design and layout parameter Layout considerations are also ... applied as input Matlab simulations indicate that more than 80 dB attenuations can be achieved at the folding frequency band edge (36.5 MHz, since MHz is the signal bandwidth) Capacitor mismatches...
... widespread pain and HPA axis function is therefore unclear and remains to be clarified The studies discussed above were conducted on small numbers of patients, which may have had an impact on the accuracy ... identified based on their pain and psychological status and whose HPA axis function was assessed Subjects completed a questionnaire that enquired about aspects of psychological status together with a history ... responsible for study conduct and manuscript revisions JM conducted data analysis and prepared the manuscript All authors have access to all data in the study and hold final responsibility for the...
... of major legal thinkers, such as H L A Hart and Hans Kelsen Here, each paradigm of an overall form of a functional legal unit is defined and differentiated from the complementary material and ... methodologies, and sanctions Also, I seek to advance and to render more articulate our general understanding of the distinctive nature of each selected functional legal unit as a whole through a frontal and ... forms” that unduly sacrifice important values, as in the case of administrative agencies that have jurisdictional and structural features in which adjudicative and administrative functions are not...
... “overall form” as the purposive systematic arrangement of a functional legal unit is analogous Just as the form of a table may be said to arrange and shape the wood, and the form of a citadel may ... said to arrange and shape the building materials, and just as both can also be said to be so arranged and shaped purposively and systematically, the form of a legislative institution, for example, ... supra n 2, vol 6, at “form” I.13; id., vol 6, at “formal” A. 3 .a P Atiyah and R Summers, Form and Substance in Anglo-American Law: A Comparative Study of Legal Reasoning, Legal Theory, and Legal...