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fine specificity of anti cd4 antibodies in hiv 1 exposed individuals with different susceptibility to hiv infection

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Báo cáo y học: "α The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis" pot

Báo cáo khoa học

... serum anti- α-actinin antibodies in lupus patients was associated with a 2.5-fold increase in the prevalence of LN [14 ] Finally, levels of anti- α-actinin antibodies correlated with those of anti- DNA ... an increased binding to α-actinin as compared with patients with no nephritis [12 ] and that pathogenic human anti- dsDNA antibodies bound strongly to α-actinin [12 ,13 ] Moreover, an increase in ... of αactinin antibodies in this cohort also has to be considered since in previous studies about 20% of SLE patients had Page of (page number not for citation purposes) increased anti- α-actinin...
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IMMOBILIZATIONS OF ANTI JEV ANTIBODIES IN HUMAN SERUM FOR DIRECT IMMUNOSENSORS

IMMOBILIZATIONS OF ANTI JEV ANTIBODIES IN HUMAN SERUM FOR DIRECT IMMUNOSENSORS

Hóa học - Dầu khí

... immobilized with anti- JEV antibodies contained serum (1mg/ml in PBS pH 7.0) (C) - The sensor coated with APTES, added 10 % glutaraldehyde (G.A) and then immobilized with anti- JEV antibodies contained ... serum (1mg/ml in PBS pH 7.0) (D) - The sensor coated with APTES, added 10 % glutaraldehyde (G.A), then protein A (1mg/ml in PBS) and immobilized with anti- JEV antibodies contained serum (1mg/ml in ... immobilize the antibodies was to 3-fold as higher as those obtained using different attachment methods  The response time of JEV antigen detection occurred was minutes and stable within 20 minutes after...
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báo cáo khoa học: "Chemical and transcriptional responses of Norway spruce genotypes with different susceptibility to Heterobasidion spp. infection." ppsx

Báo cáo khoa học

... variation in susceptibility following artificial Heterobasidion annosum inoculation of Picea abies clones in a 24 10 11 12 13 14 15 16 17 18 19 20 21 22 17 -year-old field test Scandinavian Journal of ... mechanisms [1, 2] Many of these are associated with the production of secondary metabolites to delay or stop the establishment of fungi or insects within the tree [2, 12 -14 ] Oleoresins produced in the ... (59° 01' N, 16 °49' E) and was established in 19 84 with 311 genotypes as 3-year old bare root cuttings It was planted in a Roman square design with nine replicates and single tree plots with 1. 4...
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Báo cáo y học: "Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on κ α NF-κB binding activity and TNF-α secretion of T cell" pot

Báo cáo khoa học

... 7.4 10 8 1. 6* 41 2.3* 11 3 0.9* 10 9 1. 9 25 2.9* 10 4 1. 6 20 0.9* 10 6 0.7 14 4 5.9 23 5.3* 10 2 2.6* 17 2.5* 11 6 6.4* 0.2 82 2.7 0.0 76 1. 2 91 3.5* 71 1. 7 Results of surface staining ... 3.2* 11 1 0.3* CD4 (W3/25) 55 3.2 11 6 0.8 2.5 98 1. 5 23 1. 7* 97 1. 2* 1. 5* 95 0.7* CD4 (OX35) 52 7.5 15 0 0.9 45 8.0 93 3.0 26 4 .1 1. 2* 12 1 1. 0* 0.3 10 5 1. 9 18 2.0 10 1 0.5 0.3 ... 0.0 10 7 9.0 0.5 98 2.0 0.3 82 3.3 0.0 86 7.7 70 5.5 12 2 1. 7 47 5.0 99 1. 5 31 1. 9* 93 1. 5* 28 7.2* 95 0.7* CD8 21 1. 0 16 2 1. 3 27 3.0 11 0 1. 5 33 2.0* 10 9 5.0* 39 3.2* 11 1 ...
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Báo cáo y học: " Co-receptor usage and prediction of v3 genotyping algorithms in hiv-1 subtype b’ from paid blood donors experienced anti-retroviral therapy in chinese central province" pps

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... isolates [11 ] Since the first co-receptor antagonist——Maraviroc against HIV- 1 was approved in the United States in 2007, which blocking HIV- 1gp120 from binding to CCR5, thereby preventing HIV- 1 into ... approved the final manuscript Competing interests The authors declare that they have no competing interests Page of 7 10 11 12 13 14 15 16 17 18 19 Received: May 2 010 Accepted: 22 October 2 010 Published: ... (15 .4%) VL(log10) < 18 (90.0%) 2 (10 .0%) 11 (68.7%) 7 (10 0.0%) = < VL(log10) = 40(82.6%) 6 (17 .4%) CD4+ T count (cells/ μl) p= 0.007 VL p< 0.0001...
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Báo cáo y học: " Involvement of claudin-7 in HIV infection of CD4(-) cells" pdf

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... (HT3-HT7) -gp120 T1-SP 12 -gp160B and RF 10 -gp120 SF2 HeLa -CD4 HIV Env(+) LNCaP HIV Env(+) LNCaP HIV Env(-) DU145 HIV Env(-) C B 10 00 LNCaP 10 0 HT1080 HeLa 10 PC3 0 .1 0.3 1. 0 3.0 10 .0 p24 of HIVNL4-3-EGFP-Env(-) ... http://www.retrovirology.com/content/2 /1/ 79 12 0 10 0 80 60 40 20 Env(-) only Env(-) + -gp160 Env(-) + -CLDN-7 211 Env(-) + -Pep Figure Inhibition of HIV infection by antibodies specific to CLDN-7 Inhibition of HIV infection by antibodies ... claudins Antibodies were added into both viral stocks and cell cultures for 10 minutes prior to infection at room temperature The final concentration of antibodies in the infection medium was a 1: 100...
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Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review pdf

Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review pdf

Sức khỏe giới tính

... Type of Subjects Cohort UK Cases treated at Brompton Hospital with open tuberculosis 19 05 19 14 3,326 Sinding-Larsen [11 9] Cohort Denmark Sanatorium patients with open tuberculosis 19 07 19 31 1 ,11 4 ... opening in 19 12 up to 19 27 In his report patients are PLoS ONE | www.plosone.org April 2 011 | Volume | Issue | e176 01 The Natural History of Tuberculosis Table Overview of studies included in ... doi :10 .13 71/ journal.pone.0 017 6 01. g0 01 PLoS ONE | www.plosone.org April 2 011 | Volume | Issue | e176 01 The Natural History of Tuberculosis categorized according to different categories/stages, including...
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Báo cáo hóa học: "Immunoreactivity of anti-gelsolin antibodies: implications for biomarker validation" pot

Hóa học - Dầu khí

... from HIV- infected individuals, 10 μg of human CSF from HIV- infected individuals, 20 μg of cell supernate from both HIV- infected and noninfected cells, 25 μg of monkey plasma from pre- and 10 days ... changes occurring during 1DE and transfer Immunoreactivity of gelsolin forms Figure includes a Western blot using goat anti- hGSN antibodies against a linear dilution of recombinant gelsolin In the most ... expressed in the plasma and Cerebrospinal Fluid (CSF) of Human Immunodeficiency Virus (HIV) -infected individuals with and without dementia [17 -19 ] Likewise, gelsolin circulating in the plasma of monkeys...
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Báo cáo hóa học: " The temperature arrested intermediate of virus-cell fusion is a functional step in HIV infection" ppt

Hóa học - Dầu khí

... an intermediate in the process leading to HIV infection Results To determine if TAS was an intermediate step in the process of HIV fusion leading to infection we compared the ability of known inhibitors ... then maintained at 23°C to establish TAS Soluble CD4 (PRO 542), which binds to gp120 and competes with the binding of cell associated CD4, or AMD 310 0 which inhibits CXCR4 binding, were added to ... contributes to the exposure of binding sites within gp 41 TAS contributes to the exposure of binding sites within gp 41 necessary for inhibition by C34 peptide MAGI +/+ cells were plated at 10 ,000 cells/well,...
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báo cáo hóa học:" Effectiveness and Safety of Generic Fixed-Dose Combination of Tenofovir/Emtricitabine/Efavirenz in HIV-1-Infected Patients in Western India" doc

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... worsening of an existing clinical condition (infectious or noninfectious) within months of initiation of ART Toxicity was graded according the system mentioned in the WHO ART scale-up guidelines ... safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through years in antiretroviral-naive HIV- 1- infected patients HIV Clin Trials 2007, 8 :16 4 -17 2 Abstract Gallant ... (%) 11 (24.5) 20 (22.9) Sex WHO stage before initiating current or past ART Stage I 15 (30.6) 36 (39 .1) Stage II (10 .2) 10 (10 .9) Stage III (10 .2) (9.9) Stage IV 24 (49) 37 (40 .1) Duration of HIV...
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Báo cáo y học: "Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies" ppsx

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... binding of antiSm antibodies to carboxyl-terminal SmD1 and SmD3 peptides (Fig 1) All anti- Sm sera exhibited increased binding to SmD1 peptides containing sDMA as compared with those containing ... autoantibody species in systemic lupus erythematosus Autoantibody to U1-68 kD SMP positive Percentage U1-C SmBB' SmD Ro-52 Ro-60 La histone dsDNA β2 Glycoprotein 8 /16 12 /25 11 /26 11 /22 11 /16 ... for providing clinically defined sera References 10 11 12 13 14 15 16 R28 von Muhlen CA, Tan EM: Autoantibodies in the diagnosis of systemic rheumatic diseases Semin Arthritis Rheum 19 95, 24:323-358...
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Báo cáo y học: "Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab" ppsx

Báo cáo khoa học

... resonance imaging examinations of the spine in patients with ankylosing spondylitis, before and after successful therapy with inflixi- R443 Arthritis Research & Therapy 10 11 12 13 14 15 16 R444 Vol ... according to the ASAS working group criteria for partial remission at TP1 [14 ] Partial remission was defined as a score ≤ (on a scale of to 10 ) in each of the four ASAS 20% domains, according to ... ankylosing spondylitis Retreatment depended on the duration of response to the initial treatment Of the 42 patients, 10 had to be retreated within 12 weeks after discontinuation of infliximab infusions,...
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Báo cáo y học: "Association between anti-nucleophosmin and anti-cardiolipin antibodies in (NZW × BXSB)F1 mice and human systemic lupus erythematosus" doc

Báo cáo khoa học

... References 10 11 12 13 14 15 16 17 18 19 20 R1403 Hang LM, Izui S, Dixon FJ: (NZW × BXSB)F1 hybrid A model of acute lupus and coronary vascular disease with myocardial infarction J Exp Med 19 81, 15 4: 216 -2 21 ... phosphoprotein B23 define a novel subset of patients with anticardiolipin antibodies Arthritis Rheum 19 89, 32 :11 65 -11 69 Pfeifle J, Anderer FA, Franke M: Characterisation of nucleolar proteins as autoantigens ... relationship between anti- NPM and aCL antibodies and finally define a subset of patients with aCL antibodies The association of aCL and anti- NPM antibodies in WB lupusprone mice and patients with SLE might...
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Báo cáo y học: "Value of anti-infective chemoprophylaxis in primary systemic vasculitis: what is the evidence" pdf

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... Campath-1H Intervention TS None TS recommended NI TS, fungi Optional TS TS suggested Acyc, fungi Prophylaxis 14 9 47 15 5 20 32 10 0 13 7 71 N 18 40 18 12 16 .8 18 12 60 51 (17 ) NI (13 ) 33 (11 ) NI NI ... PN (1) , CC (1) Pneu (20), Sep (1) , Abs (1) NI Type of serious infections (number of patients)a (3.5) (6) 19 (27) 15 (19 ) 11 (17 ) (4) (8) 0 0 (3) (3) 49 (24) Total deaths (%) (33) (33) (26) (13 ) ... TB (1) Sep (1) and NI Sep (1) and NI Pneu (1) , Sep (1) , Asp (1) Death due to or in conjunction with infection (% of total deaths) Vol 11 No Mazlumzadeh et al 2006 [8] RCT Matteson et al 19 96...
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Báo cáo y học: " Predictors of disease progression in HIV infection: a review" ppt

Báo cáo khoa học

... R, Wasi C, Heneine Page 12 of 14 (page number not for citation purposes) AIDS Research and Therapy 2007, 4 :11 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9 11 0 11 1 11 2 11 3 11 4 11 5 11 6 11 7 11 8 W, Choopanya ... Type -1 Infection - Relationship of Risk Group http://www.aidsrestherapy.com/content/4 /1/ 11 119 12 0 12 1 12 2 12 3 12 4 12 5 12 6 12 7 12 8 12 9 13 0 13 1 13 2 13 3 13 4 and Age to Rate of Progression to Aids ... 2007, 4 :11 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Chinen J, Shearer WT: Molecular virology and immunology of HIV infection Journal of Allergy and Clinical Immunology 2002, 11 0(2) :18 9 -19 8...
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Báo cáo y học: "Immediate determination of ACPA and rheumatoid factor - a novel point of care test for detection of anti-MCV antibodies and rheumatoid factor using a lateral-flow immunoassay" pdf

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... O, Chollet Martin S: Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti- CCP- Page of 10 11 12 13 14 15 negative patients and for monitoring infliximab therapy ... Therapy 2 010 , 12 :R120 http://arthritis-research.com/content /12 /3/R120 Abbreviations ACPA: autoantibodies against citrullinated protein/peptide antigens; anti- MCV: autoantibodies against mutated ... MCV+ RF IgG- 13 0 13 MCV- RF IgG+ 15 10 13 38 MCV- RF IgG- 34 11 2 18 4 330 total 10 8 12 2 200 430 ELISA for anti- MCV antibodies was positive with and for RF with 35 patients Therefore, specificity...
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Báo cáo y học: "Frequent coexistence of anti-topoisomerase I and anti-U1RNP autoantibodies in African American patients associated with mild skin involvement: a retrospective clinical study" doc

Báo cáo khoa học

... anti- Sm antibodies [27] A study from Finland reported 12 % of coexistence of anti- topo I and anti- U1RNP [30] Detection of anti- topo I in MCTD patients indicates coexisting anti- topo I and anti- U1RNP ... with anti- topo I P Caucasian (n = 15 ) 55 .10 ± 12 .9 46.6 ± 8.6 56.5 ± 11 .5 45.9 ± 13 .2 Male 26% 17 % Male 20% 38% Caucasian 68% 33% Anti- U1RNP 13 % 50% African American Latin 21% 11 % 67% 0.059 Anti- Sm ... SSc specificity of anti- topo I and triggered much confusion and Table Clinical characteristic of six cases with anti- topo I coexisting with anti- snRNPs autoantibodies Case Sm, U1RNP Sm, U1RNP U1RNP...
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Báo cáo y học:

Báo cáo y học: "Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors" pptx

Báo cáo khoa học

... 04 03 1. 0 10 02 0.00 1. 0 10 12 127 12 128 12 1 31 01 1.0 10 07 0.08 1. 0 10 06 1. 0 10 04 0.04 12 142 capture viral load 12 143 1. 0 10 04 1. 0 10 03 0.02 1. 0 10 02 0.00 1. 0 10 01 0 .10 12 140 1. 0 10 07 ... monkey 12 127 16 18 2.7 × 10 3 49 1. 8 × 10 3 26 18 4.7 × 10 4 41 6.6 × 10 3 18 11 1. 3 × 10 4 51 3 .1 × 10 3 20 46 6.6 × 10 4 53 20 12 133 25 96 3.4 × 10 4 35 1. 9 × 10 3 25 40 6.9 × 10 4 66 1. 1 × 10 4 12 142 35 ... tonsillar 1. 2 × 10 8, a Ad5-SIV tonsillar × 10 11, b Ad5-SIV tonsillar × 10 11, b group 12 127 12 128 12 1 31 1 213 7 SCIV [VSV-G] tonsillar 1. 8 × 10 9, a group 12 133 12 136 12 142 12 143 SCIV [VSV-G] intravenous...
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Báo cáo y học: "Mutations in matrix and SP1 repair the packaging specificity of a Human Immunodeficiency Virus Type 1 mutant by reducing the association of Gag with spliced viral RN" ppsx

Báo cáo khoa học

... RNA [17 ,18 ] However, viral RNA lacking SL3 is still encapsulated into the virion [11 ,19 ], as SL1, SL2 and SL4 also interact with the NC domain during packaging [7 ,16 ] Within the virion, HIV- 1 genomic ... NLΔSL1 -19 07 had a C1907T mutation in the SP1 region and NLΔSL1- 913 / 19 07 harbored both mutations Equal amounts of p24normalized NL4-3, NLΔSL1, NLΔSL1- 913 , NLΔSL 119 07 or NLΔSL1- 913 /19 07 were used to ... -376.5 NL -19 07 NLΔSL1 -378.2 -363 .1 NLΔSL1- 913 -363.0 NLΔSL1 -19 07 -364.6 a Genomic RNA nt 456 to 2080 of NL4-3, NL- 913 and NL -19 07, and nt 456 to 2037 of NLΔSL1, NLΔSL1- 913 and NLΔSL1 -19 07 were...
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