...
pattern matching, syntactic and semantic analy-
sis, and acoustic analysis can be helpful in detect-
ing and correcting these repairs. We use pattern
matching to determine an initial set of possible ...
10,517 sentences of varying lengths, it pulled out
500 as possibly containing a repair and missed 97
sentences actually containing a repair. Of the 500
that it proposed as containing a repair, ...
edits, and also including the original string un-
changed. Each of these strings was analyzed by
the parser. When the original sequence did not
60
parse, but one of edits resulted in a sequence...
... chemokines in monocytes and
macrophages (including Kupffer cells) [41, 42], and
ethanol-induced mucosal injury in the upper
gastrointestinal tract leading to increase in the
permeability of ... . Interestingly, HMGN3 has been
found to be associated with resistance against
anticancer drugs including vinblastine, topotecan,
paclitaxel and doxorubincin inhuman hepatocellular
carcinoma ... concentration of ethanol in HepG2 cells.
Moreover, it constitutes a necessary step in the
understanding of the molecular mechanisms involved
in alcohol-induced effect inhuman hepatocellular
carcinoma...
... deletion abolished binding of an U1snRNP molecule in this position and activated a 3¢ss lying 12 nucleotides
upstream of this element. In the last case, binding of hnRNP E1 and U1snRNP to a silencer ... Italy
Introduction
Towards the end of the 1970s, in the beginning of
pre-mRNA splicing research [1,2], defining exons and
introns was essentially based on observing the final
composition of the ... recognition in the normal splicing
process [55]. First, U1snRNP binding to an intronic
splicing processing element has been found to inhibit
pathological pseudoexon inclusion in intron 20 of the
ATM...
... erythrocytes in the extent of binding with the
lectins concanavalin A, Lens culinaris agglutinin
(LCA), and Ricinus communis agglutinin (RCA)
(Fig. 3), ruled out the blood origin and supported the
renal ... butyrylcholinesterase activity
assayed in kidney. This proposal is in agreement
with the cytochemical staining of acetylcholinesterase
in the capsule of Bowman [41] andof acetylcholines-
terase and ... pathological signs of
Alzheimer’s disease in the brain in vivo.
Neurobiol Aging doi:10.1016/j.neurobiolaging.2010.04.
028.
26 Vidal CJ (2005) Expression of cholinesterases in brain
and non-brain tumours....
... also
contains a GAL4 gene under the control of the GAL10 pro-
moter. The induction of the yeast, by galactose containing
media, results in overexpression of GAL4, in turn inducing
an increase of the ... function of increasing amount of total
proteins in membrane fractions from I7 yeast strain induced at
15 °C, and from yeast expressing SSTR2 as a control.
J. Minic et al. Expression of olfactory ... for increasing the
yield of properly folded recombinant human gamma
interferon from inclusion bodies. J Biotechnol 52, 127–
133.
Expression of olfactory receptors in yeast for screening J. Minic...
... trans-side of the membrane.
Moreover system y
+
L is inhibited by
L
-leucine in the
presence, but not in the absence of Na
+
.
The small inhibition of
L
-arginine in ux by
L
-leucine in
the absence of ... defective
transport of the cationic amino acids lysine, arginine and
ornithine at the basolateral membrane of the polar epithelial
cells in the intestine and renal tubules. LPI is caused by
mutations in the ... required, were incuba-
ted for 1 min at 37 °C in a Dubnoff water bath under gentle
shaking in the presence of 1 lCiÆmL
)1
L
-[2,3,4-
3
H]arginine,
unlabelled
L
-arginine and
L
-leucine when required...
... role in the correct folding,
maturation, and targeting of this protein to its final
destination [30]. To establish further the role of the
propeptide in the processing and maturation of cathep-
sin ... cathep-
sin E from lysosomal enzymes.
Role of the N-glycosylation of cathepsin E
in processing and maturation
To determine the role of N-glycosylation in the correct
folding, processing, maturation, and ... maturation, and trafficking
must be of particular importance.
In this study, to understand the molecular basis of
the processing and intracellular trafficking of cathep-
sin E, we constructed a variety of...
... learning and training.
It
is in tight connection with gaining new set of knowledge, skills and abilities that an employee
need for quality performance with the new and more demanding tasks and ... definition and its meaning, it is very important to define the process of career
development and its influence on an individual in a company. Career development is
represented by a set of correlated ... apprentices. Their main activities are training, mentoring, leading and
influencing others and taking care and responsibility for the work of the younger colleagues.
In the previous stages, an employee...
... studies carried out in
40% TFE in an H
2
O mixture [38]. According to studies of
CRH binding to single bilayer egg phosphatidylcholine
vesicles, the developmentof the intramolecular interaction
with ... 3082–3090.
44. Jaravine, V.A., Alexandrescu, A. & Grzesiek, S. (2001) Observa-
tion of the closing of individual hydrogen bonds during TFE-
induced helix formation in a peptide. Protein Sci. 10, ... main chain
torsion angles in proteins: prediction of NMR coupling cons-
tants for native and random coil conformations. J. Mol. Biol. 255,
494–506.
27. Wu
¨
thrich, K. (1986) NMR of Proteins and...
... hypoxia may increase tran scription of the HO-1
gene through a certain protein factor in RPE cells. These
results indicate that RPE cells maintain retinal homeostasis
by repressing or inducing the ... outer segments of photo-
receptors through i ts large numbers of villi, and is involved
in phagocytosis of shed outer segments [1] andin uptake,
processing, and transport of retinoids [2]. RPE ... determinant for the hypoxia-mediated induction
of HO-1 expression in D407 cells. In addition, hypoxia
coordinately and rapidly induced expression of both HO-1
and Bach1 mRNAs in cultured rat and...
... adenosine
triphosphate (ATP), 4-aminopyridine, aprotinin, 1-chloro-
2,4-dinitrobenzene, clotrimazole, creatine kinase, creatine
phosphokinase, daunorubicin, dideoxyforskolin, iso-
butylmethylxanthine ... addition of half the original packed
cell volume of cold solution L and incubated at 37 °Cfor
30 min resulting in spontaneous formation of spectrin-
actin-free vesicles [28]. After incubation, ... RPMI-1640) in a 5% CO
2
humi-
dified incubator at 37 °C. The L23/R and MOR/R sublines
were maintained in the presence of 0.2 lgÆmL
)1
and
0.4 lgÆmL
)1
doxorubicin, respectively. The cells were kept
in...
...
kept in view, and that by [Pg 463] carelessness in the drawing two of the rays are
crowded out and terminate against the side of a neighboring ray. In copying and
recopying by free-hand methods, ... with the use of clay and
a capacity in handling it that, with advancing culture, brought all nature within the
reach of the potter and made it assist in the processes of variation and development. ...
observation of incidental resemblances. This same figure, in use by the Indians of the
interior of the continent, is regarded as symbolic of the whirlwind, and it is probable
that any symbol-using...
... peak
increase of approximately 53% in the number of CD34
expressing cells andand a 90% increase in CD133 cells
in circulation. Furthermore, a significant augmentation
of cell s possessing hematopoietic ... marrow injury conditions [43], subsequent studies
have expanded this finding to situations of inflammation
[44], and peripheral tissue injury [45-47]. Hematopoietic
stem cells are being increasingly ... recognized as having
diverse non-hematopoietic functions including produc-
tion of angiogenic cytokines [48], and acting as an
“innate” immune cell capable of rapidly differentiating
into dendritic...