factors that influence bioavailability
Báo cáo khoa học " Structure elucidation and antioxidant activity of a novel polysaccharide isolated from Tricholoma matsutake " ppt
... of 1200–1000 cm−1 in the IR spectrum suggested that the monosaccharide in TMP-A had a pyranose-ring [21] The absorption at 875.43 cm−1 indicated that TMP-A had -glucopyranose linkages, which ... GC–MS The information in MS showed that fragment ion peaks were consistent with the data of d-configuration monosaccharide fragment ions peaks which can be concluded that the glucose, galactose and ... indicated that (1 → 4)-linked--dglucopyranose was one of the largest amounts residue of the polysaccharide structure, the branched residue was (1 → 4,6)linked --d-glucopyranose revealing that (1...
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Báo cáo vật lý: "Evaluation of In Vitro Antioxidant Activity of 5H-dibenz[b,f]azepine and Its Analogues" ppt
... activity on human LDL oxidation, whereas compounds (a) and (d) contain free amino groups (N–H bond) that can quench the radical and may inhibit the LDL oxidation.11,25 Introducing the electron donating ... of the synthesised compounds (Fig 3) The antioxidant activity of BHA and AA was still lower than that of the compounds (a) and (d) In general, the antioxidant activity on human LDL oxidation observed ... was in the following order: (d) > (a) > AA > BHA > (b) > (c) > (f) > (e) These results predict that the Antioxidant activity (%) Antioxidant activity (%) M 100 100 5µM 80 80 60 60 40 40 20 20...
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Báo cáo y học: "Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent" pptx
... impression gained from these studies was that while vitamin E is safe and well-tolerated, it confers only modest benefits Some studies not support the hypothesis that TD is mediated through free radical ... [15] we have shown that 6,7,8,9-tetrahydro-N,N,-di-n-propyl-1H-benz [g]indole-7-amine (PBIA) (Figure 1) acts in vivo as a functional dopamine receptor partial agonist It is known that a partial agonist ... hypothesized that it might be capable of penetrating the blood-brain barrier in a considerable degree Additionally, the presence of the tosyl group might shift the agonistic activity to that of an...
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Báo cáo y học: "Antioxidant activity of tuberosin isolated from Pueraria tuberose Linn" pot
... presence of 3-OH makes the compound more potent than that of 5-OH group [39] From the structural comparison of these compounds, it is clear that tuberosine has 5-OH group, where as quercetin has ... exposed to LPS Interestingly, our data show that tuberosin significantly inhibited the iNOS protein in western blot analysis The results suggested that tuberosin is inhibiting the expression ... Therefore, these antioxidants have variety of other biological responses, because of their indirect influence on inflammatory and immunity pathway To name a few, these includes eugenol, gallic acid...
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Antioxidant activity of essential oils
... activities of basil and laurel essential oils, it seems interesting that they showed good antioxidant activities despite the fact that the major constituents of these oils, i.e., estragol and 1,8-cineole, ... color.19 Further, our study has confirmed that no single testing method is sufficient to estimate the antioxidant activity of essential oils It was shown that the RANCIMAT test is not appropriate ... to different plant families were determined The results are summarized in Table II It was found that the essential oils of all analyzed plants showed very different antioxidant capacities Stronger...
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Evaluation of the antioxidant activity of scutellaria baicalensis and its constituents in diabetic rats
... or model was that among patients with type DM, glucose control as assessed by HbA1c level, regardless of the specific drug, would reduce the risk of cardiovascular events The fact that the trial ... for preventing diabetic complications that already includes two bloodpressure - lowering drugs, others have suggested combinations of four to five drugs that may be customized separately for ... benefit and more favourable side-effect profiles Emerging evidence is in favour of the concept that oxidative stress plays an important role in the development and progression of insulin resistance...
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Nghiên cứu về hoạt tính chống oxy hóa của các cây thuộc African Antioxidant Activity of African Medicinal Plants
... carbohydrates [13] Antioxidants are compounds that protect biological systems against the potentially harmful effects of processes or reactions that can cause excessive oxidation [14,15] They ... defense system that deactivates these highly reactive free radicals [16] Antioxidant enzymes (made in the body) and antioxidant molecules (found in plants) soak up all the excess energy that these ... supplement the diet with antioxidant compounds that are contained in natural plant sources [17] The World Health Organization (WHO) has estimated that 80% of earth’s inhabitants rely on traditional...
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Báo cáo y học: "Pravastatin Provides Antioxidant Activity and Protection of Erythrocytes Loaded Primaqe"
... with pervious study reported that in vitro exposure of RBCs to oxidants resulted in damaging of protein in addition to increase PCO formation [27] This may suggest that oxidant drugs increase ... presence of primaquine was greater than that of control in addition to pravastatin treated erythrocytes This finding are similar to the previous study reported that exposure of antimalarial drugs ... beneficial effects on several cardiovascular alterations [14] Previously the study demonstrated that treatment with PS has protective effect against oxidative stress [15] The present study was...
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Báo cáo hóa học: "Effects of Pin-up Oxygen on [60]Fullerene for Enhanced Antioxidant Activity" pptx
... solution using a UV-vis spectrometer by comparison of the peak absorbance around 360 nm in water to that of pristine C60O in cyclohexane (Fig 2a) On the other hand, PVP/C60O and C60On have not been ... ½ b Àcarotene ½LOO ¼ kc ½b-carotene kc ½b-carotene þ kf ½fullerene Rf ¼ ð1Þ It was found that the b-carotene bleaching was significantly suppressed by the increasing amount of antioxidants, ... although C60O was more effective than C60 in all tested ranges of concentration It was also noted that the entrapped PVP and CD exerted no appreciable effect on the antioxidant activity of guest...
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Báo cáo y học: " Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system" pdf
... interests The authors declare that no competing interests exist for any of the authors of this work and that partial funding by the company that supplied the test oils had no influence on the outcome ... system, the possibility remains that other components of the mixed oil preparation activated additional antioxidant or anti-inflammatory-associated transcription factors that contributed to the observed ... assay Preliminary experiments had shown that treatment of the cells for the 15 exposure period was inadequate to cause significant activation of Nrf2 above that seen in medium or soy-treated controls...
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anthocyanin – study of extraction from basella rubra l and verifying antioxidant activity, application in identificating di sodium tetra borate in food
... and the pH result that measured from borax solution was approximately 8.4, therefore, the reason that make anthocyanin change to violet is that borax provide a medium with pH >8 that make Anthocyanin ... fact that some banned preservatives that still have been using, are threatening consumers health Di Sodium Tetra Borate or Borax are using as an anti-fungal compound in food preservation, that ... different when compare with result of Nhan et al 2011 that acetone gave high outcome while distilled water in this result gave high yield These factors have a statistically significant effect on...
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Báo cáo y học: "Anticancer Activity of the PR Domain of Tumor Suppressor RIZ1"
... was that RIZ1 may augment the expression of nuclear factor of activated T cell (NFATc1) [24], which induces breast cancer cell invasion via cyclooxygenase-2 [29] Therefore, we hypothesize that ... observation in this study was that the RIZ1 mRNA expression is elevated in all stages through the progression of breast cancer (Fig 1A) This is in contrary to the previous studies that RIZ1 was under-expressed ... consistent with a study on cancer stem cells that only 11-35% breast cancer cells sustained tumor growth through cell division [33], implicating that RIZ1 was likely overexpressed and acted as...
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ANALYSIS OF MICROBIAL COMMUNITY STRUCTURE AND IN SITU ACTIVITY OF NITRIFYING BIOFILMS
... biofilm Microsensor measurements indicated that oxygen penetrated approximately 150 µm into the autotrophic nitrifying biofilm The NH4+ and NO2- profiles showed that NH4+ and NO2- were both consumed ... cultivation, which circumvents the biases associated with culture-dependent techniques It must be noted that this approach enables identification and quantification of “as yet unknown and/or uncultivated ... taken from the reactor was acclimated in the medium a few hours before the measurement, to ensure that steady state profiles were obtained Estimation of Consumption and Production Rate Profiles...
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Photocatalytic bactericidal activity of silver-sensitized titanium dioxide on Micrococcus lylae
... showed that, bacterial survival was not affected by mixing with the three photocatalysts up to 60 (Fig 1) No Ag+ released from Ag1 and Ag2 might take part in killing bacteria It is also possible that ... UV irradiation This result showed that Ag sensitization on TiO2 could surely promote bactericidal activity but the Ag/TiO2 molar ratio should be as high as that in the Ag2 sample No difference ... that smaller amount (0.1 m gml-1) of it is enough to provide the same bactericidal activity as in 0.2 mg ml-1 It is important in cost saving in real application Some previous studies showed that...
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Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf
... accumulation of globin or vacuolization These results confirm that MA does not hinder the initial processing of globin and, in consequence, it is unlikely that falcipains are targeted by the drug Effect of ... inhibition of the MSP1 processing (Fig 2B) These results indicate that at least PfSUB1 is inhibited by MA in erythrocyte cultures, corroborating that this compound behaves as a serine protease inhibitor ... encompassing cysteine, aspartic, serine and metalloproteases The results, shown in Table 1, indicate that MA is a strong inhibitor of the metalloprotease thermolysin, showing also FEBS Journal 278...
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Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt
... states that h cannot be greater than the number of ligand-binding sites present within the molecule This suggests either that the active form of TorD could contain at least three active sites, or that ... biological systems that utilise domain swapping to regulate activity For example, glyoxylase I of Pseudumonas putida is a metastable domain-swapped dimer with two Zn2+ cofactors that also exists ... form of the protein, suggesting that domainswapping is required to generate the active site In addition, site-directed mutagenesis identifies one residue, D-68, that is involved in the substrate...
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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... here that EGF treatment also activates JNK, and that this activation is required for the protective effect of EGF, at least in HEK-293T cells We propose that it is through JNK activation that ... demonstrating further that ubiquitylated tBid is degraded in the proteasome, and that there is an appreciable ubiquitylation level of tBid, even without overexpression of Itch Note that Itch is present ... promotes tBid degradation B A Azakir et al 4) These results together confirm that Itch and tBid are interacting proteins, and that Itch induces increased proteasomal degradation of tBid On the contrary,...
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Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
... electrophoretic mobility of 30 K with that of each mGFP construct As shown in Fig 6D, the electrophoretic mobility of 30 K was closer to that of mGFP239 This result suggested that mGFP–calpain was cleaved ... reported that calpain associates with a subset of ESCRT-III and its related proteins: charged multivesicular body protein (CHMP)1A CHMP1B, CHMP2A, CHMP4b, CHMP4c and CHMP7 [28] We also showed that ... MIM2 The former forms an amphipathic helix that binds to the groove between VPS4 MIT domain helices and [29,30], and the latter forms a Pro-rich strand that binds between helices and [31] Human...
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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... to note that three of the four completely conserved residues that lie close to the substrate binding site (K12, H95 and E97) are located in the vicinity of residue 74 (Fig 6) Figure show that Thr75, ... summarized in Fig It is evident that the Y74W* mutant shows an enhancement of activity of 21.9-fold over the concentration range 2.540 lm, strongly suggesting that the loss of activity at low ... barrel fold observed in TIMs is a robust structure that is incompletely denatured in urea solution Previous studies of PfTIM wild-type established that considerable secondary structure is maintained...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25