fabrication procedure of poly si thin film solar cells on glass at seris
Effects of anti malaria drug artesunate in the treatment of rhinovirus induced asthma exacerbation
... for the recruitment of lymphocytes to the sites of inflammation On the basis of the function of NF-κB in the pathogenesis of asthma, manipulation of NFκB pathway can be a promising method to fight ... infection exacerbate the production of lung cytokines and chemokines 79 4.4 RV infection exacerbate the expression of inflammatory mediators 79 4.5 Effects of RV infection on NF κB translocation ... transactivation 80 4.6 Artesunate treatment reduces the exacerbation of recruitment of inflammatory cells in mice with allerfic airway inflammation and inflammatory cell infiltration and mucus...
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Báo cáo y học: "Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on κ α NF-κB binding activity and TNF-α secretion of T cell" pot
... Co Ltd) stimulation with ConA were higher than those of PBStreated rats, while T cells of the RIB5/2-treated rats showed proliferation rates similar to those of T cells from PBS-treated animals ... PRIMATIZED antiCD4 monoclonal antibody, SB-210396 (IDEC-CE9.1) Responsiveness correlates with duration of monoclonal antibody coating, CD4 receptor modulation and decrease in number of activated lymphocyte ... potency of the anti-CD4 mAbs on the proliferation of CD4+ T cells in a total T-cell population was excluded by using purified CD4+ T cells They showed a clearer inhibition of their proliferation rates...
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Báo cáo khoa học: Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity pdf
... phosphorylation sites of dHAND are located within the bHLH domain Therefore, we speculated that phosphorylation of these sites might affect the DNA binding and/or dimerization activities of dHAND ... indicated that the major phosphorylation sites of dHAND were located within Fig Analysis of the interaction between dHAND and Akt (A) GSTpull down assay was performed using cell extract of 293T cells ... (bottom) (B) Effects of Akt overexpression on dHAND phosphorylation Cell lysates were prepared from 293T cells expressing AU5-dHAND and HA-Akt, and the phosphorylation status of dHAND was analyzed...
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Báo cáo khoa học: Photosynthetic acclimation: Structural reorganisation of light harvesting antenna – role of redox-dependent phosphorylation of major and minor chlorophyll a/b binding proteins pot
... for state transitions, in particular the postulated docking site for the association of the mobile LHCII with PSI under State conditions The evidence for the lateral migration of a fraction of LHCII ... of state transitions represents a short-term adaptation of the photosynthetic apparatus to the conditions of imbalanced illumination of PSII or PSI It occurs on a timescale of seconds to minutes ... compared with State (Fig 1) Under the conditions of overexcitation of PSI (or preferential illumination with light 1), oxidation of the PQ pool occurs followed by de-activation of LHCII-specific...
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Báo cáo khoa học: The common phospholipid-binding activity of the N-terminal domains of PEX1 and VCP/p97 doc
... Constellation of hydrophobic residues with conserved basic residues on the surface of the N-terminal domains (NDs) of PEX1 and valosine-containing protein (VCP) (A) Conserved hydrophobic residues ... well-conserved basic residue (R135) located at one end of a shallow groove, which is assumed to be a substratebinding site in NSF [34,50] Furthermore, a constellation of well-conserved hydrophobic residues, ... activity of adaptor domains Fig Sequence comparison of the N-terminal domain (ND) of PEX1 with that of other related proteins (A) Schematic representation of the domain architecture of AAA-ATPases...
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Báo cáo khoa học: CpG methylation of the CENP-B box reduces human CENP-B binding pptx
... methylation occurs at the C5 atom of cytosine by the action of methyltransferases To evaluate the effect of CpG methylation on the CENP-B–DNA interaction, we modeled additional methyl groups at ... representation of the complex formation rates shown in panel A 32P-labeled unmethylated (d) and methylated (s) CENP-B box DNAs Formation rates (%) are plotted against the concentrations of the ... In eukaryotic cells, methylation of the cytosine within the CpG dinucleotide is an epigenetic DNA modification that is important for heterochromatin formation The human a-satellite consensus sequence...
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Báo cáo khoa học: A sucrose binding protein homologue from soybean exhibits GTP-binding activity that functions independently of sucrose transport activity pptx
... SBP-mediated regulation of alternative carbohydrate uptake systems Despite the functional characterization of SBP, potential post-translational modifications that could regulate its function have ... 45 [24] Transient expression of S64/SBP homologue in soybean suspension cells The pUFVS64 clone was modified by site-directed mutagenesis to create an EcoRI restriction site immediately Ó FEBS ... electroporation, soybean suspension cells at days after passage were recovered by centrifugation at 200 g, washed three times and concentrated twice with electroporation buffer, incubated with...
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Báo cáo khoa học: Dynamics, stability and iron-binding activity of frataxin clinical mutants pdf
... with what had been noticed at the protein purification level because expression of frataxin mutants always results in formation of aggregates and inclusion bodies This was further investigated by ... show that this mutation results in a frataxin variant with a decreased conformational stability and iron-binding capacity From a structural point of view, our results demonstrate that none of the ... found that there is an inverse correlation between the level of protein expression and the aggregation rate [23], so that proteins are only marginally soluble to function and aggregation can result...
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Báo cáo khoa học: Replacement of helix 1¢ enhances the lipid binding activity of apoE3 N-terminal domain pot
... structural data and localization of the LDLR recognition sequence to helix in the NT domain, these observations are consistent with the concept that the conformational status of the NT domain modulates ... protect LDL from lipolysis-induced aggregation at any concentration examined, HT apoE3-NT was more effective, consistent with formation of a stable binding interaction In a competition experiment, ... dimyristoylphosphatidylglycerol (DMPG) vesicle solubilization was monitored as a function of time (Fig 6) Whereas DMPG vesicle light scattering intensity did not change upon incubation at 23 °C in buffer alone,...
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Báo cáo y học: "The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-κB transcriptional activity in models of rheumatoid arthrits" pps
... single-cell suspensions, with the subsequent removal of red blood cells with Tris-NH4Cl solution After lysis of red blood cells, the cells were cultured in 24-well plates at a concentration of ... processes involved in the pathogenesis of RA, including immunoregulation, regulation of adhesion molecules, and modulation of cytokine signaling However, the role of estrogen has not R433 Arthritis ... confirmed (data not shown), which was consistent with our hypothesis that ER regulates NF-κB at the transcriptional level [16,27] A similar suppression of adjuvantinduced inflammatory gene expression...
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Báo cáo y học: " Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells" ppsx
... serum of a SLE patient (at a final concentration of 20% vol/vol) with or without necrotic cell supernatant (at a final concentration of 20% vol/vol) was then added After 24 hours, the concentrations ... http://arthritis-research.com/content/12/3/R87 Page of 13 Figure Effects of BAY11 on pDC survival and maturation 10-9 M to × 10-7 M of BAY11 does not affect viability or maturation of pDCs Human pDCs were preincubated ... that BAY11 acts as an inhibitor of IRF7 nuclear translocation and indicates that the inhibition of type I IFN production by BAY11 is due to its inhibitory function on the nuclear translocation...
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r.b.''s activity book 1
... Dear Parent/Caregiver , The National Association of Pediatric Nurse Practitioners (NAPNAP) and our nearly 7,000 pediatric nurse practitioners are dedicated to helping parents understand ... badge! For more on food safety at home, visit www.fightbac.org Time for a Treat Eating healthy is great – but an occasional treat can be fun, too! Fill in the letters to find the treats and to ... our programs with content that explores areas related to hygiene, nutrition, exercise, and personal safety NAPNAP and the LYSOL® Products Brand Team share a collaborative relationship, and working...
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r.b.''''s activity book 2
... one at a time, holding handrail Slide down, sitting up — feet first! • On the swings, stay seated and hold on with both hands • On the seesaw, sit with one same-sized child on each side Hold onto ... • Don’t give information to someone you don’t know • Only open emails from people you know • Tell a parent/adult if you see anything that makes you uncomfortable On the Playground • On the ... Dear Parent/Caregiver , The National Association of Pediatric Nurse Practitioners (NAPNAP) and our nearly 7,000 pediatric nurse practitioners are dedicated to helping parents understand...
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r.b.''s activity book 4
... Dear Parent/Caregiver , The National Association of Pediatric Nurse Practitioners (NAPNAP) and our nearly 7,000 pediatric nurse practitioners are dedicated to helping parents understand ... health needs of their growing children We are proud to play a part in providing you with an educational program and activity book that gives your child helpful information on issues related to his ... our programs with content that explores areas related to hygiene, nutrition, exercise, and personal safety NAPNAP and the LYSOL® Products Brand Team share a collaborative relationship, and working...
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Báo cáo Y học: Barley a-amylase Met53 situated at the high-affinity subsite )2 belongs to a substrate binding motif in the bfia loop 2 of the catalytic (b/a)8-barrel and is critical for activity and substrate specificity pot
... reect that substrate binds at (an) as yet unidentied site(s) which is (are) situated far from the site of catalysis and can compensate for hampered substrate contact, caused by mutation at subsite ... that combination of the present mutations and mutations at other subsites can accentuate the suppression of activity for shorter substrates and further develop the enzyme specicity as done recently ... The action pattern of porcine pancreatic a-amylase in relationship to the substrate binding site of the enzyme J Biol Chem 245, 454465 32 Hiromi, K (1970) Interpretation of dependency of rate parameters...
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Tài liệu Báo cáo khoa học: Secondary substrate binding strongly affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases docx
... one-third on Azo-wheat AX compared to that of wildtype XBS The trends observed on chromophoric substrates are confirmed on natural substrates because modification of the SBS decreases the rate at which ... concentration needed to obtain E590 = 1.0 after subtraction of the control value (no enzyme) under the conditions of the assay and the assumption that no substrate exhaustion occurs Solubilization of ... indicate that these mutations create a ‘sticky patch’ causing aspecific binding to all kinds of substrates, rather than enhancing the specific binding of xylan substrates in a correct orientation...
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Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc
... exclusively (LlCBP33A) in an insoluble form (inclusion bodies) The culture conditions (temperature, isopropyl thio-b-d-galactoside concentrations and duration of culture) were varied in an attempt ... structural information with the results of site-directed mutagenesis studies showed that the surface of family 33 CBPs contains a patch of highly conserved, mostly polar residues that are important ... illustrated by the production of (GlcNAc)2 during the initial linear phase of the degradation reaction Note that the enzyme concentrations used in the two reactions differed by a factor of 10...
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Tài liệu Báo cáo khoa học: Regulation of cathepsin B activity by 2A2 monoclonal antibody docx
... using Coomassie blue staining 4748 Size exclusion chromatography The ability of 2A2 mAb to cause dissociation of cystatin C from cathepsin B was assessed by size exclusion chromatog¨ raphy on ... obtained by native gel electrophoresis Size exclusion chromatography The dissociation of cystatin C from the cathepsin B ⁄ cystatin C complex by 2A2 mAb was tested by size exclusion chromatography ... of cathepsin B activity The formation of the cathepsin B ⁄ cystatin C complex was seen as a shift of the elution peak of cathepsin B (Fig 6A) The addition of 2A2 mAb to the preformed cathepsin...
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Tài liệu Báo cáo khoa học: Calcium-binding to lens bB2- and bA3-crystallins suggests that all b-crystallins are calcium-binding proteins pptx
... emission recorded from 300–450 nm Calcium was added to the desired concentration and incubated for before recording the emission spectra (A) Emission spectra of bB2crystallin: Final concentration ... spectrum upon calcium titration, suggesting calcium ligation The large size of the protein due to known homodimerization and higher oligomer formation with increasing protein concentration makes ... studies implicate the importance of bB2-crystallin expression for normal physiological functions in nonlenticular tissues In conclusion, our data demonstrate that all b-crystallins are moderate affinity...
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Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf
... activation of platelets, regulating the stability of platelet adhesion and aggregation [20,21] We now advocate that PI3-Kb also plays a role in the prolongation of thrombin-induced Ca2+ signaling ... process that is still dependent on normal Ca2+-ATPase function A remarkable finding is that the persistent effect of P2Y12 on Ca2+ mobilization relies on prolonged phospholipase C activation Similar ... were examined on thrombin + ADPinduced Akt activation In platelets that were stimulated with thrombin alone or in combination with ADP, Akt was phosphorylated at its activation site of Ser473, peaking...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25