extrapolation of toxicity values from animals to humans
CURRENT BASIC AND PATHOLOGICAL APPROACHES TO THE FUNCTION OF MUSCLE CELLS AND TISSUES – FROM MOLECULES TO HUMANS pdf
... Approaches to 32 the Function of Muscle Cells and Tissues – From Molecules to Humans 2.3 Mechanisms of cytosolic Ca2+ oscillations in VSMC Ca2+ oscillations are one of the ways that VSMCs respond to ... difference up to atm (Fukushima, 1981) Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues – From Molecules to Humans Determination of the critical electron dose to impair ... rate of muscle myofibrils, expressed as percentage of myofibrils contracted in response to ATP in the microscopic field (Suda et al.,1992) Note that contraction of myofibrils in response to ATP...
- 400
- 583
- 0
Báo cáo y học: "Parallel evolution of conserved non-coding elements that target a common set of developmental regulatory genes from worms to humans" doc
... lineages to regulate the expression of a core set of regulatory genes The extreme sequence conservation of CNEs likely reflects the functional importance of these elements as components of the ... transcription factors in C elegans [30] Out of 1,241 of the wCNEassociated genes, 108 (8.7%) are annotated as transcription factors according to DBD and 137 out of 1,241 (11.0%) of the wCNE-associated ... because of their co-evolution from a common metazoan ancestor, the core GRNs of different animal groups often utilize the same regulatory genes As a result, distinct yet parallel sets of CNEs...
- 14
- 257
- 0
Báo cáo khoa học: Kinetics of electron transfer from NADH to the Escherichia coli nitric oxide reductase flavorubredoxin pdf
... Reduction of FlRd by avorubredoxin reductase Spectral analysis of FlRd is complex due to the partial overlap of the optical contribution of its redox cofactors Figure shows the absorption spectrum of ... presence of an excess of NADH, two events can be deconvoluted: the reduction of [Fe-Cys4] (monitored at 560 nm) and the formation of semiquinone FMN (monitored at 390 nm after subtraction of the ... kinetics of electron transfer to (as well as within) this enzyme Because the efciency of NO detoxication by FlRd (and FDPs in general) clearly depends on the availability of electrons at the site of...
- 10
- 404
- 0
The History of Australian Exploration from 1788 to 1888 ppt
... any distance from the settlement The work of exploration was toilsome and difficult, from the lack of beasts of burden Each member of the party had a heavy pack to carry, and when to that was ... History of Australian Exploration from 1788 to 1888 Complied from State Documents, Private Papers and the most authentic sources of information Issued under the auspices of the Government of ... Destruction of the boats Walk to Perth Great sufferings Death of Smith Eyre and the overlanders Discovery of Lake Hindmarsh Exploration of Gippsland Eyre's explorations to the north Discovery of Lake Torrens...
- 301
- 470
- 0
listening to the sirens musical technologies of queer identity from homer to hedwig
... fourth-generation photocopies Her application of feminist theory to music of all types from Monteverdi to Madonna—ushered in what came to be called “new musicology.” Under this rubric, inquiries into music ... diction and rhetoric of that earlier epic and claiming the power to bestow knowledge and pleasure, like the epic Muses: Come hither, Odysseus of many stories, great glory of the Achaeans Stop your ... spite of the enchantment that betrays a “readiness to leave the wandering of the Odyssey in favor of the splendid toils of the Iliad,”21 Homer forces his subject to stay on course, binding him to...
- 371
- 1,800
- 0
Effects of Minimum Drinking Age Laws Review and Analyses of the Literature from 1960 to 2000
... self-purchase *8% of underage college students and 10% of underage H.S students reported use of false ID *21% of students reported use of false ID No Cross-sectional X *Low levels of enforcement of drinking ... reported purchase attempts (44% of college students) *Increased attractiveness of customer and positive mood of server associated with less likelihood of request for proof of age Cross-sectional -Yes ... related factors that can be deemed to mediate the relationship between drinking age law and outcomes of interest Such factors include selfreported ease of access to alcohol and sources of alcohol,...
- 21
- 521
- 0
university of california press from marriage to the market the transformation of womens lives and work aug 2006
... work, to employers eager to have greater access to women’s labor, and to government of cials increasingly reluctant to support women’s work in the home This led to a series of steps that took ... twentieth century, from the rise of single mothers among the poor to the recent time crunch faced by many families, are tied to the failure to consider this half of their story This oversight ... Inside Out the disappearance of an old set of family values that once stabilized home life They point to a loss of discipline, particularly among the poor, or to the rise of individualism, especially...
- 311
- 412
- 0
university of california press a critical history of early rome from prehistory to the first punic war feb 2005
... simplest to smelt from ore and to fashion into objects, and it was therefore the first metal to be mined and worked by prehistoric cultures, but it is also the softest of the three metals, even softer ... of life Consequently, much of human prehistory and history has been a struggle to develop a material culture that mitigates the effects of climate, environment, and geography The prehistory of ... for travel to and from southern France to the west and the central Danube to the east Although the Po Valley was the last area of Italy to succumb to Roman arms, its geographical ties to continental...
- 421
- 379
- 0
practical markers of the transition from aerobic to anaerobic metabolism during exercise
... for several three-point segments: (a) from Min to VT-1 ( P < 0.05), (b) from the Min to VT ( P < 0.001), (c) from VT + to End-1 ( P < 0.05), and (d) from VT + to End ( P < 0.001) In contrast, for ... significant for several three-point segments: (a) from Min to VT-1 ( P < 0.001), (b) from Min to VT ( P < 0.001), (c) from VT + to End-1 ( P < 0.01), and (d) VT + to End ( P < 0.01) In contrast, for FS, ... are related to perceptions of exertion Furthermore, the lactate and ventilatory (gas exchange) thresholds have been shown to correspond to stable ratings of exertion, regardless of differences...
- 11
- 268
- 0
báo cáo hóa học: " Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008" pot
... prognostic value of quality of life scores: preliminary results of an analysis of patients with breast cancer Surg Today 2000, 30:255-261 Butow PN, Coates AS, Dunn SM: Psychosocial predictors of survival: ... Physical aspects of QOL were significantly related to survival The change in scores of both overall QOL and the physical aspects of QOL were also significant predictors of survival Butow et al [54] ... patients with recurrent symptomatic malignant pleural effusions: an assessment of the prognostic values of physiologic, morphologic, and quality of life measures of extent of disease Chest 2000, 117:73-78...
- 21
- 717
- 1
Báo cáo y học: " Correction: Frequency, course and correlates of alcohol use from adolescence to young adulthood in a Swiss community survey" ppt
... course and correlates of alcohol use from adolescence to young adulthood in a Swiss community survey BMC Psychiatry 2008, 8:5 Pre-publication history The pre-publication history for this paper ... correlates of alcohol use from adolescence to young adulthood in a Swiss community survey BMC Psychiatry 2010 10:15 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient ... 2010, 10:15 http://www.biomedcentral.com/1471-244X/10/15 Page of Correction After the publication in this journal [1] we became aware of the fact that the article contained wrong data in figure...
- 2
- 279
- 0
Báo cáo y học: " Chronic obstructive pulmonary disease, asthma and protective effects of food intake: from hypothesis to evidence?" docx
... COPD symptoms), although the consistency of the evidence is a matter of judgement (see Table 1) Because of the overlap of indicators of asthma and COPD in adults, it is often not clear from observational ... symptoms in smokers [30] review Lungs of smokers are exposed to high levels of oxidants and other inflammatory agents, which has raised the question whether dietary factors are expected to have ... 139 ml higher FEV1 and a 50% lower prevalence of COPD symptoms than an unfavourable intake of these foods [20] The contribution of each of these foods to the overall beneficial effect was largely...
- 4
- 204
- 0
Báo cáo khoa học: "Reproductive performance of Norwegian cattle from 1985 to 2005: trends and seasonality" potx
... culled because Figure fertility from 1989 animals of poor Percentages of inseminated animals reported culled because of poor fertility from 1989 to 2005 Page of (page number not for citation ... age of heifers at 1st insemination was at a low of 15.6 months in 1991 and increased to 16.2 months from 2001 to 2005 The average CFI interval has increased from a low of 79 days in 1990 to a ... figure The major part of the inseminations is performed with semen from the Norwegian Red (NRF) breed, varying from a high of 97.8% in Total number performed from semen from bulls of the NRF Figure...
- 7
- 266
- 0
Báo cáo y học: "Lymphocytes, apoptosis and sepsis: making the jump from mice to humans" docx
... too early in the hospital course to catch the period of maximal apoptosis Also, information on the effects of severe sepsis on the receptor-mediated pathway of apoptosis, particularly FADD and caspase ... Bcl2, caspases), only deletion of Bim is associated with complete protection from apoptosis [13] However, it is important to note that blockade of lymphocyte apoptosis is not always protective ... Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis Crit Care 2008, 12:R128 Martin GS, Mannino DM, Eaton S, Moss M: The epidemiology of sepsis in the United States from...
- 2
- 335
- 0
Solutions to improve marketing activities of manulife Vietnam from 2007 to 2010
... thesis to the Board of Examiners Doctor Le Tan Buu Dean of Faculty of Commerce and Tourism University of Economics Ho Chi Minh City i Style Definition: TOC 1: Tabs: 6.1", Right,Leader: … TABLE OF ... express my sincere thanks to Professor Le Tan Buu – The Head of Commercial-Tourist Department of the Economic University of Ho Chi Minh city who directly gave me advices to make the research and ... helps from them Firstly, I would like to thank to all Professors of the Course for their instruction on all the newest and the deepest knowledge and experience to us Secondly, I would like to express...
- 140
- 634
- 3
Building business strategy for retail banking in bank for investment anf development of Vietnam (BIDV) from 2011 to 2015
... factors as identified in the internal audit process; (ii) Assign a weight that ranges from 0.0 (not important) to 1.0 (the most important) to each factor; (iii) Assign a to rating to each factor ... in years from 2008 to 2010 is shown in the following table: Table 2.1: BIDV’s business performances Billions of VND Indicators I Size Indicators Total assets Total mobilized fund (end of period) ... compares to the same period last year and accounted for 13.5% of the total fees from service activities The retail banking customers basis continues to increase with the number of customers is...
- 101
- 1,422
- 2
Cement business strategy building of cosevco6.,jsc from 2011 to 2015 and the vision towards 2020
... factors in the internal factor evaluation, the total of important points can be classified from the lowest level of 1.0, to the highest level of 4.0, and the average point of 2.5 The total of ... situation of Cosevco6 Joint Stock Company from 2006 to 2010 Part III: Cement business strategy building of Cosevco6 Joint Stock Company from 2011 to 2015 and the vision towards 2020 -8- Capstone ... organizations to be always active, to catch timely opportunities, to turn threats into opportunities, to invert situations, to win competitors, and to develop stably and effectively The main target of the...
- 91
- 363
- 0
Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008