explain the role of communication and interpersonal interactions in health and social care p1
Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... of GSK3 (using Li or SB-415286)appears to be sufficient for inducing activation of GS in muscle and fat cells, and that inhibition of the kinasepotentiates insulin action in muscle of insulin-resistant ... increases in glucose uptake and glycogen synthesisallowing for more effective ÔchannellingÕ of glucose intoglycogen in response to insulin. However, one of the potential difficulties in interpreting ... phosphatidylinositol3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammaliantarget of rapamycin (mTOR) pathway in the L-leucine-inducedup-regulation...
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Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... phenylalanine was thereforemutated to Ala, Leu, Trp or Tyr. These mutations may in uence the shape and volume of the acyl binding pocket and thereby alter the binding mode and affinity of the enzyme ... PAA and derivatives thereof, while maintaining the hydrophobicity of the binding site.To test the effect of the mutations on the specificity forphenylacetylated substrates, the steady-state kinetic ... kcatrepresents the rate of acylation and Kmequals the binding constant of the substrate to the free enzyme. The results then indicateÓ FEBS 2002 Role of active-site phenylalanines in penicillin acylase...
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báo cáo khoa học: "The role of 18F-FDG-PET/CT in the preoperative staging and posttherapy follow up of gastriccancer:Comparison with spiral CT" docx
... oravoiding unnucessary laparotomy [17]. The guidelinealso recommends PET for evaluation of therapyresponse and to make the decision of continuing the ongoing therapy or stopping and redirecting the ... chemotherapy programme again.Lesions in the lung in 1 patient and in the proximaljejunal segments of the intestine in another patient werenot FDG avid. So they were accepted as non malignant and ... important limitation th at the number of patients issmall especially in the first group, the number of studiesintheliteratureinvestigatingtheroleofPETinthediagnosis of distant metastasis preoperatively...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production
... create signiịcant changes in the genetic makeup of plants and animals due to the random recombination and sorting of thousands of genes. As a result of intervention by people, the hybrid seed corn ... throughout the world bears little resem-blance to teosinte, the original ancestor of corn. The newer techniques involv-ing genetic engineering, on the other hand, allow for the transfer of a fewgenes ... commercially introduced in the U.S. in 1996 and have been rapidly adopted by farmers. It has been estimatedthat 24% of the corn and almost 70% of the soybeans and cotton grown in the U.S. in 2001...
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Tài liệu Báo cáo khoa học: Role of receptor-mediated endocytosis, endosomal acidification and cathepsin D in cholera toxin cytotoxicity pdf
... amounts of proteinfrom 3Y1-Ad12 cell lysates confirmed the absence of cathepsin D in nontransfected cells, and the presence of both the 31 kDa mature cathepsin D and the 45 kDa procathepsin D in cathepsin ... bafilomycin and the cathepsin D inhibitor pepstatin Apartially inhibited, both in vivo and in vitro, the cAMP response to choleratoxin. This cathepsin D-dependent action of cholera toxin under the con-trol ... decrease of 3–10-fold in the apparent affinity of the toxin for the enzyme [6]. More-over, both chloroquine and monensin interfered with the ATP-dependent intraendosomal degradation of internalized...
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Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx
... binding properties The affinity of wild-type and mutant forms for the cofactor was measured to evaluate the impact of the mutations on the structure of the PLP binding site.Because PLP binding ... interacts with the phosphate moiety of PLP; E57Â is crucial in the binding of the l-serinehydroxyl group [15] and in the catalysis of the hydrox-ymethyltransferase reaction [16]; and Y65Â interactswith ... to explain the increase of the dissociation constant of the monomer–dimer equilibrium determined by the muta-tions. The results obtained in the present study alsoshow that the monomeric form of...
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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx
... likelythat the increased rate of 13C label incorporation into the C6position of glycogen in the ADM group is indicative of activated 6-phosphofructo-1-kinase, which can lead toincreased13C labeling ... concentrations. There-fore, an understanding of the regulation of these fluxes canprovide important insights into the mechanisms and poten-tial treatment of diabetes. The rates of glycolysis and gluconeogenesis ... C1, the C6 and C2–C5 signals were measured simultaneously for the first time in vivo, which provide the basis for the estimation of direct and indirect synthesis of glycogen in the liver. The...
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The role of floating-rate bank loans in institutional portfolios pdf
... Russell Investments // Role of bank loans in a rising rate environment / p 7 Bank loans in rising interest rate environments In the past 20 years (since 1992), there have been three periods of significant ... surprise. The duration of the Credit Suisse Leveraged Loan Index is significantly lower than durations in the traditional fixed income asset classes, reflecting the prevalence of floating rate instruments ... price movements. The default rate is the default rate of a bank loan portfolio (historically, 2%–3%), and the recovery rate is the amount of principal recovered in the event of default (historically,...
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Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx
... [16–18].Interestingly, the sum of ATP and UTP was two-foldhigher than that of CTP and GTP, and the ratio of dATP and dTTP to dCTP and dGTP was also 2 : 1[16,17]. This fact is in accordance with the ... after 3 min and thendeclined, while the formation of [3H]ATP was increasedlinearly with time within the first 15 min. After 30 min, the reaction reached equilibrium (Fig. 4A). Furtherexperiments ... substrate in a totalvolume of 20 lL. The reaction was initiated by the addition the enzyme (100 ngặreaction)1for the determination of NTP synthesis rates and 0.51 ngặreaction)1for the deter-mination...
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Báo cáo khoa học: The heterogeneity of mast cell tryptase from human lung and skin Differences in size, charge and substrate affinity ppt
... heparin-binding site, a region of positive surface charge extending along the left- and right-hand sides of the ring in Fig. 10A [23]. This region iscomprised of five histidines, nine lysines, and ... were incubated with the filters for45 min at a concentration of 5 lgặmL)1,andtheblotswashed and incubated with diaminobenzidine and hydrogenperoxide. A combination of the biotinylated lectins ... lgặmL)1heparin.Fig. 8. Mathematical modeling of the behavior of a mixture of isoforms of an enzyme. (A) Hanes plot of a theoretical mixture of 5 isoforms of an enzyme for the following cases:...
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Báo cáo sinh học: " Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons" docx
... rhadinovirusesbelonging to the RV2 lineage of KSHV-likerhadinoviruses. The primers and probe for this assay werebased on sequences within the 3' end of the ORF 60 cod-ing sequence and the ORF 59/60 intergenic ... assay in this study. Dots represent residues identical to those in the RRV sequence, and highlight the similarity of the primer sequences within the RV2 lineage of rhadinoviruses and the dissimilarity ... divergence of the Old World primate rhadinoviruses and their hosts [26]Identification of a novel RV2 rhadinovirus in the baboon, Papio cynocephalus, using the RV2 QPCR assayTo further determine the...
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báo cáo hóa học: " The role of cumulative physical work load in symptomatic knee osteoarthritis – a case-control study in Germany" potx
... between the questionnaire and observation ratings of 0.49 for frequency of lifting, carrying, and transferring6–15 kg. Concerning the frequency of lifting, carrying, and transferring 6–15 kg, the ... 1.1–6.1Kneeling/squatting and lifting/carrying combinedcBoth no kneeling/squatting and no lifting/carrying 65 22.0 137 41.9 1.0 - 1.0 -Kneeling/squatting >0 – <870 hrs. or lifting/carrying >0 ... number of squatting and the duration of kneeling work. D'Souza et al. [20] examine the relation-ship between the daily amount of kneeling and knee oste-oarthritis in the subset of participants...
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báo cáo hóa học:" Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons" pot
... divergence of the Old World primate rhadinoviruses and their hosts [26]Identification of a novel RV2 rhadinovirus in the baboon, Papio cynocephalus, using the RV2 QPCR assayTo further determine the ... assay in this study. Dots represent residues identical to those in the RRV sequence, and highlight the similarity of the primer sequences within the RV2 lineage of rhadinoviruses and the dissimilarity ... regions of identical sequenceswithin both the ORF 59 and ORF 60 coding regions and the ORF 59/60 intergenic region. As shown in Figure 2, aregion of 71 identical nucleotides in the MneRV2 and RRVsequences...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25