... relations" (1 970 , p 53) In the 1 980 s, with the emergence ofthe biologically oriented neoKraepelinian school of psychiatrists (Blashfield, 1 984 ; Guze, 1 9 78 ; Klerman, 1 9 78 ) andthe advent ofthe DSM-III ... Popular Adoption ofthe Biomedical Model 17 Psychiatric Endorsements ofthe Biomedical Model 20 The Biomedical Model: Definition 26 The Biomedical Model: Critique One 32 The Biomedical Model: Critique ... disease ofthe brain; the psychiatrist is and must remain the primary scientist and guardian ofthe mentally disturbed If the central problem in the etiology and treatment 32 The Biomedical Answer of...
... efforts ofthe members ofthe Special Committee on Ethics and Professionalism who provided input and direction for this project Model Guidelines for the Appropriate Use of Social Media and Social ... the patient; likewise, the patient may not be able to verify that a physician is on the other end ofthe communication For that reason, the standards of medical care not change by virtue ofthe ... professional relationships However, these benefits must occur within the proper framework of professional ethics, and physicians need information on the importance of maintaining the same professional...
... participated in the design ofthe models proposed and in the drafting and revision ofthe manuscript 11 12 13 14 15 16 17 18 Astell CR, Chow MB, Ward D: Sequence analysis ofthe termini of virion and replicative ... hours at 37 C and then electrophoresed on a 1.2% agarose gel in 1X TBE buffer at 75 V The Bam HI / Mlu I I digestion generated three fragments of approximately 2 78 , 2 686 , and 486 1 bp The 2 78 bp fragment ... from the transfection of LuIII Lt-Lt/pGlu∆Xba, contributed in the analysis and interpretation ofthe data, participated in the idea and design ofthe models proposed and in the drafting and revision...
... in the formation of retinal NV in the later stages ofthe OIR model In this study, we investigated the temporal and spatial distribution of microglial cells during the different stages ofthe ... retina, the mean number of microglial cells Page of from the three fields of each counting position (central or peripheral zone, and layer) was calculated Then, the mean and standard error of these ... avascular zone andthe peripheral zone (B) Cryosection ofthe eye showing the superficial layer (s) andthe deep layer (d) of microglia (GFP, green) The nuclei (DAPI, blue) ofthe retinal ganglion...
... participated in the design ofthe models proposed and in the drafting and revision ofthe manuscript 11 12 13 14 15 16 17 18 Astell CR, Chow MB, Ward D: Sequence analysis ofthe termini of virion and replicative ... hours at 37 C and then electrophoresed on a 1.2% agarose gel in 1X TBE buffer at 75 V The Bam HI / Mlu I I digestion generated three fragments of approximately 2 78 , 2 686 , and 486 1 bp The 2 78 bp fragment ... from the transfection of LuIII Lt-Lt/pGlu∆Xba, contributed in the analysis and interpretation ofthe data, participated in the idea and design ofthe models proposed and in the drafting and revision...
... 1:100 and 0.23 at 1:200 79 7 amino acids, a pI of 6.6 and a molecular weight of 88 kDa Consistent with the estimated molecular size of hen mesothelin we observed two predominant trails of protein ... Ordonez NG: Value of mesothelin immunostaining in the diagnosis of mesothelioma Mod Pathol 2003, 16:192-1 97 doi:10.1 186 / 175 7-2215-4-12 Cite this article as: Yu et al.: The hen modelof human ovarian ... between exon and exon 10 It was detected in 57% (12/21) of ovarian cancers (Figure 2A), including 75 % (3/4) of serous, 33% (2/6) of mucinous, 25% (1/4) of endometrioid and 86 % (6 /7) of mixed histology...
... the sequence ofthe exponentially distributed independent random variables with the parameter μn+1 (μn+1 > 0), and νμn+1 (ξn+1 ) is random variable defined by TheModelof Stochastic Control and ... r(xk , μk ) + k=1 n EV (xn ) EV (x1 ) − n−1 n n−1 (3 .8) TheModelof Stochastic Control and Applications 415 By the formulas (3 .7) and (3 .8) we have U Ex S ⇒S n−1 U lim Ex n→∞ Since lim n→∞ n−1 ... Ax2 + Bx + C n→∞ Proof The proof is carried out similarly as in Lemma 4.3 Theorem 4.1 The constant S andthe function V (x) defined in Lemma 4.5 satisfy the following Bellman’s equation S + V (x)...
... measured the levels of TGF-β1 in irradiated TSK and C57BL/6 mice skin and correlated them with the level of tissue injury and fibrosis Both free (active) and total TGFβ1 was higher in C57BL/6 mouse ... extension of 1.0 mm in the C57BL/6 mice (p < 0.05) (Fig 1b) The average leg extensions at the same time in unirradiated TSK and C57BL/6 were 9.5 mm and mm respectively The implication is that there ... 2), the quantity of both free and total TGF-β1 were significantly higher in the skin of C57BL/6 mice compared to TSK mice (p < 0.05) The TGF-β1 values correlated with the degree of skin injury and...
... constructs of four theories of behavior that have been applied in many health contexts over the past 30 years [21] These include the Theory of Reasoned Action, the Theory of Planned Behavior, the Health ... measure ofthe central constructs ofthemodel Attitudes can be assessed indirectly by first calculating the product of each behavioral belief and its related outcome evaluation, and then summing the ... make the decision for themselves, instead of making a shared decision with their physician Had the developers ofthe video DESI explicitly considered the behavioral targets ofthe intervention and...
... 2 87 ( 4):L 774 -83 Pinto MC, Garcia-Barrado JA, Macias P: Resveratrol is a potent inhibitor ofthe dioxygenase activity of lipoxygenase Journal of agricultural and food chemistry 1999, 47( 12): 484 2- 484 6 ... under the direction of PG, DKH and JLH EB and JLH prepared the figures and manuscript, which was reviewed and approved by each ofthe coauthors 17 18 Acknowledgements 19 The authors thank Ms ... Power) The antioxidant activity of a 1:10 (wt/vol) extraction was determined in triplicate by the FRAP method [ 28] 10 µL ofthe sample or standard, 30 µL of distilled water and 300 µL of FRAP...
... constructs of four theories of behavior that have been applied in many health contexts over the past 30 years [21] These include the Theory of Reasoned Action, the Theory of Planned Behavior, the Health ... measure ofthe central constructs ofthemodel Attitudes can be assessed indirectly by first calculating the product of each behavioral belief and its related outcome evaluation, and then summing the ... make the decision for themselves, instead of making a shared decision with their physician Had the developers ofthe video DESI explicitly considered the behavioral targets ofthe intervention and...
... infants, 19 97 to 2000 J Pediatr 2003, 143:S1 27- 132 DeVincenzo JP: Therapy of respiratory syncytial virus infection Pediatr Infect Dis J 2000, 19 : 78 6 -79 0, discussion 80 2 - 78 4, 81 1 - 78 3 Greenough ... at 1, 5, 8, 24, 48 and 72 hours and after 7, 10, 37 and 59 days post-infection One lung per animal was processed for QPCR analyses, the other for infectivity assay A) Levels of positive and negative ... design ofthe study and analysis and interpretation of data HB conceived ofthe study, participated in its design and coordination and helped to draft the manuscript All authors read and approved the...
... andthe NIH Guide for the Care and Use of Laboratory Animal Welfare Act (7 U.S.C et seq.) The animal use protocol was approved by the Institutional Animal Care and Use Committee (IACUC) ofthe ... various kinds of protein that have their own epitopes and are complex The Der p allergen reacts with about only 40% of allergic sera to HDM, andthe Der p and allergens react with about 80 % of allergic ... Yoo TJ: The effect of vaccination with DNA encoding murine T-cell epitopes on the Der p and induced immunoglobulin E synthesis Allergy 2001, 56 :74 1 -74 8 Lewis DB: Allergy immunotherapy and inhibition...
... this be? The answer lies in the fact that the signature of transformation is not in the expression ofthe oncogene protein but in the alteration in the DNA by the oncogene In the case of Bcr-Abl, ... 3->3 3->2 50 77 50 77 92 74 57 The term fs(Pre) is the survival fraction of a tumor cell's population prior to the application of a targeted therapy; Ω(Pre)-> Ω(Post) represents the change in transformed ... the range of fs to be between 0.5 and 0 .77 for CML stem cells Holtz et al [19] studied the separate effects of Imatinib on CML stem cells and committed progenitor cells and derived an index of...
... animal model affects the hallmarks of PD produced (Bezard et al., 19 97) Moreover, the gender, age, sex and body weight ofthe mice are major factors that influence the sensitivity ofthe drug andthe ... down the progression ofthe disease 1.6 Pathological hallmarks of PD The archetypal pathological characteristic of PD involves the loss ofthe dopaminergic (DA) neurons The DA neurons ofthe substantia ... augmented risk in the development of PD 1 .8 Animal models of PD Over the recent decades, researchers have mainly relied on rodents to modelthe features of PD Among the many models, the commonly used...