... to the external carotid artery to anastomosis of the internal carotid artery; in one case, the subclavian artery to the common carotid artery to anastomosis of the internal 265 carotid artery; ... Common carotid artery DS angiographs: occlusion at the beginning of internal carotid artery, with the remaining external carotid artery No formation of anatomosis between the external carotid ... hydrocephalus 3.2 Radiology features 1) Location of occlusions: the beginning part of the common carotid artery in cases, the beginning part of the internal carotid artery in cases, the cavernous sinus...
... of regulating its target mRNAs (See Fig 1) Deregulation of this processing Role of miRNAs in disease Gene regulation by miRNA can affect a wide variety of cell functions, such as regulation of ... malignant tissues offers the possibility of identifying new methods of diagnosing early stage incidence and discovering new therapies for the treatmentof OVCA With the advent of new miRNA technology, ... cancer treatment Using data from miRNA profiling and knowledge of familial history of a certain diseases will help in developing miRNA-based personalized therapy Detailed understanding of the...
... analysis requires fluorescent labeling of individual samples; 50% of antigens detected Detection of autoantibodies characteristic of eight autoimmune rheumatic diseases, including autoantibodies ... complexity of fluorescence-based bead and tag systems Microfluidics approaches Microfluidics utilizes microchannels for analysis of antigen–autoantibody interactions Small quantities of biomolecules ... quantitation of binding kinetics and detection of low-affinity interactions are among the important advantages of this system Arrays of living cells 292 Several groups have described arrays of living...
... endovascular repair represents a less invasive therapy for the treatmentof all kinds of aortic diseases, including urgent management of polytraumatic patients affected by aortic dissection Moreover, ... best treatmentof this kind of complications, especially in young patients Nobody knows the potential risk of aortoesophageal fistula[13] In conclusion, TEVAR has significantly improved the treatment ... Fonseca JH, de Souza JA, Camargo Carvalho AC, Buffolo E: Endovasculartreatmentof thoracic disease: patient selection and a proposal of a risk score Ann Thorac Surg 2002, 73:1143-8 Canaud L,...
... because of the presence of neurological compression by the hematoma that was progressively enlarging Some case reports [8-10] have demonstrated the feasibility ofendovasculartreatmentof an axillary ... B: Endovascular management of unusual aneurysms of the axillary and subclavian arteries J Endovasc Surg 3(4):389-395 10 Vijayvergiya R, Kumar RM, Ranjit A, Grover A: Endovascular management of ... aneurysm until now In our Centre, 12 endovasculartreatmentof subclavian-axillary arteries aneurysms have been performed for the last five years, using traditional endovascular methods and with good...
... contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense Acknowledgements None ... nerve repair procedures at the time of this writing Conclusion Embolosclerotherapy is recommended in isolation or as part of a multi-staged approach for treatmentof appendicular vascular malformations ... series of eighty-seven patients who underwent a total of 399 sessions of percutaneous ethanol sclerotherapy Five nerve palsies were reported; three facial and two peroneal A mechanism of injury...
... for the treatmentof thoracoabdominal aneurysm that would Page of decrease the risk of visceral ischemia This device, however, is still in the experimental phase Conclusion The use ofendovascular ... necks of the aneurysm, the vessels involved in the aneurysm, and the location of tears in aortic dissection One of the major challenges is the risk of paraplegia in patients who undergo surgical treatment ... JC: Endovascular repair of abdominal aortic aneurysms and other arterial lesions J Vasc Surg 1995, 21:549-557 Dake MD, Kato N, Michell RS: Endovascular stent graft placement for the treatment of...
... properties of H2S 1.1.1.2 Toxicity of H2S 1.1.1.3 Biosynthesis of H2S 1.1.1.4 Storage and metabolism of H2S 1.1.1.5 Biological role of H2S in CNS 1.2 Alzheimer’s disease ... institutionalization of patients An additional impact of AD is on the day to day activity of patients (activities of daily living) These symptoms result in adverse effects of quality of life, impact ... THE ROLE OF HYDROGEN SULFIDE IN THE CENTRAL NERVOUS SYSTEM: IMPLICATIONS IN TREATMENTOF ALZHEIMER’S DISEASE BHUSHAN VIJAY NAGPURE (M.B.B.S., Maharashtra University of Health Sciences,...
... TRANSPLANTATION OF MESENCHYMAL STEM CELLS FOR THE TREATMENTOF PARKINSON’S DISEASE IN A MOUSE MODEL CHAO YIN XIA MD A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY ... induced Parkinson’s disease models through the interaction of NKG2D receptor and Rae-1γ ligand… 91 Transplantation of MSCs in treatmentof PD………………………………….93 3.1 Genetic background of stem cells in ... Professor He Bei Ping, Department of Anatomy, National University of Singapore, for his valuable suggestions and help during this study I am very grateful to Professor Ling Eng Ang, ex-Head of...
... 1.3.2 Effect of H2S on heart diseases 30 1.3.2.1 Effect of H2S on ischemic heart diseases 30 1.3.2.2 Effects of H2S on heart failure (HF) 33 1.3.3 Effect of H2S on blood ... Biosynthesis of H2S in mammals Figure 1.4 Catabolism of H2S in mammals Figure 1.5 Origins and disposal routes of H2S Figure 1.6 Effect of H2S on electrophysiology of heart Figure 1.7 Mechanisms of H2S-induced ... proposed mechanisms underlying effects of H2S are strongly suggestive of the lack of understanding of H2S action Inhibition of RAS has been implicated in prevention of HF In fact, ACE inhibitors and...
... effect of NaHS on cell viability in the presence and absence of various PKC isoforms inhibitors…………………………………………51 Figure 2.5 Involvement of PI3K/Akt pathway in the neuroprotective effects of NaHS…………………………………………………………………………… ... activation of the UPR signaling components have been reported to participate in the killing of dopaminergic neurons [4, 50] 19 Table 1.1 Various treatments for Parkinson's disease Treatments ... the pathogenesis of various neurodegenerative diseases Table 1.3 Neuropathological roles of H S CNS diseases Parkinson disease (PD) Alzheimer's disease (AD) Down's syndrome Evidences References...
... concentration of OXANO in the blank sample was subtracted from that of the corresponding test sample Around ten per cent of the signal was diminished as a result of the inhibitors 2.2.5 Measurement of MCP-1, ... The outcome of the PCA of the radical data, data concerning the degree of arteriosclerotic disease and some relevant clinical data are shown in Figure In order to increase the lucidity of the figure ... pathogenesis of brain damage due to various causes Our results of a positive correlation between levels of free radicals and MMP-9 at operation for carotid artery stenosis further support this role of...
... damage of DNA; (2) oxidations of unsaturated fatty acids in lipids; (3) oxidations of amino acids in proteins; and (4) inactivation of specific enzymes through oxidation of catalytic cofactors ... decreased risk of aging, chronic disease, or cancer chemoprevention and treatment in the general population 11.3 Parkinson’s Disease Parkinson’s disease (also known as Parkinson disease or PD) ... development and severity of diseases based on inflammatory processes including atherosclerosis and ischemic stroke, neurodegenerative diseases of aging, and certain cancers The first report of the anticancer...
... in obesity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and treatmentof these conditions Suppression of ANGPTL2 as an effective strategy ... coronary artery disease express higher levels of ANGPTL2 mRNA than tissues from nonsmokers with similar disease [20] Because smoking is closely associated with the development of inflammation and ... constitute promising treatments for obesity and metabolic diseases associated with chronic inflammation (Fig 1) Activation of ANGPTL6 ⁄ AGF counteracts obesity and related metabolic diseases ANGPTL6...
... indicate the feasibility of using inhibition of MDR1 as an approach to the treatmentof Fabry disease Although the efficacy may not, as yet, be as dramatic as ERT, inhibition of MDR1 may prove most ... Gb3 in the serum of wildtype mice was below the background of this assay MDR1 inhibition and GSL storage disease ERT and CsA treatment Effect on serum Gb3 Owing to the difficulty of drug administration ... ERT a-Galactosidase treatment will eliminate the serum Gb3 levels [9] and the effect of a maintenance dosing of CsA on the recovery of serum Gb3 levels after termination of ERT was determined...
... and/or effectiveness of hydroxyurea treatmentof hematologic diseases, the toxicity of hydroxyurea in the treatmentof any disease, and the barriers to the treatmentof sickle cell disease with hydroxyurea ... the use of hydroxyurea and to clarify its role in the treatmentof patients with sickle cell disease the Office of Medical Applications of Research (OMAR) at the National Institutes of Health ... of the review We applied evidence grades to the bodies of evidence about the efficacy and/or effectiveness of hydroxyurea for the treatmentof sickle cell disease in one assessment In terms of...
... Collateralization of Striatofugal Neurons and Co-localization of Dopamine Receptors One of the important series of data that challenged the concept of segregated direct and indirect striatofugal pathways ... gathered a group of experienced and recognized authorities in the field who have provided authoritative reviews that define the current state of the art of surgical treatmentof Parkinson’s disease and ... emulated by Nazaroff, who in 1927 reported on the injection of alcohol into the same area of the cortex with variable results (3) The first surgical treatmentof Parkinson’s disease (PD) was...
... on the importance of obtaining sputum cultures at the time of completion of the initial phase oftreatment in order to identify patients at increased risk of relapse • Extended treatment is recommended ... months oftreatment has been completed If cavities were seen on the initial chest radiograph or the acid-fast smear is positive at completion of months of treatment, the continuation phase oftreatment ... risk of relapse to determine optimal length oftreatment Identification of such factors would enable more efficient targeting of resources to supervise treatment In addition, identification of...