effects of reserpine and isocarboxazid in the frog
Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... that activation of the dopaminergic system by the inhibition of dopamine transporter may be involved in the mechanism of unwanted effects (deterioration of psychosis) of sertarline in this case, ... fluvoxamine binds to sigma-1 receptors in the intact human brain at therapeutic doses [25], suggesting that sigma-1 receptors are involved in the active mechanisms of fluvoxamine [19] Interestingly, ... related to the mechanisms of the opposite effects of the two SSRIs in this case Thus, it seems that the antagonism of sigma-1 receptors by sertraline may be involved in the recurrence of psychotic...
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A computational study to investigate the effects of insulation and EGR in a diesel engine
... reduce the extent of burning of last portions of fuel injected into the prechamber The unburned fuel in the prechamber may therefore increase with load, but its burning rate in the main chamber ... because of the increase of injection pressure and the increase of the injected fuel mass due to the increased effective flow area with increased nozzle needle lift Therefore, as shown in Figure ... (BSFC) of the IDI engine to increase and the total engine efficiency to decrease compared to that of a DI diesel engine Because of these disadvantages of the IDI diesel engines, most engine research...
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The Effects of Sensitization and Habituation in Durable Goods Markets ppt
... no change in the qualitative nature of the results Therefore, we used the assumption of requiring only strict increase in quality We also tested other initial levels of α0, β0, and Φ0 The results ... specify the size of the required quality premium, say 25%, this would merely serve to change the point in the quality space where the discontinuities occur In the case of end-point optima, the resulting ... we determine the boundaries of the sub-spaces of the quality variable These correspond to the quality levels offered in the past at which consumers had made purchases Then, for each of these subspaces,...
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báo cáo hóa học: " e differential mediating effects of pain and depression on the physical and mental dimension of quality of life in Hong Kong Chinese adults" pptx
... the negative effects of pain on physical QoL The indirect effect of depression on the pain-QoL link pathway was 0.08, indicating that about 75% of the effect of pain on QoL impacted through the ... mediated the painQoL link for the physical aspect (Model 4) When pain was the mediator, it accentuated the negative effects of depression on mental functioning The indirect effect of pain on the depression-QoL ... 0.043, suggesting that about 28% of the effect of depression on the mental aspect of QoL went through the mediator of pain, and over 72% of the effect was direct When depression was the mediator,...
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Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene ppt
... after the administration of the drugs The ED50 was determined using the up -and- down method described by Dixon [6] As shown in Fig 1, before microinjection of the vectors (pre, day), the antinociceptive ... protocol had the approval of the Institutional Animal Care and Use Committee of the National Defense Medical Center (Taiwan, Republic of China) Direct microinjection of dsAAV vectors into the spinal ... libitum The care of animals was carried out Page of in accordance with institutional and international standards (Principles of Laboratory Animal Care, National Institutes of Health), and the protocol...
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Báo cáo khoa học: "The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass graftin" pdf
... coordinating the study and in the interpretation of data and were involved in drafting the manuscript JP was involved in the interpretation of the data and revised the manuscript for important intellectual ... unit (ICU) and in the intermediate care unit was at the discretion of the physicians and nurses in charge With the exception of the hemodynamic goals given above and the prohibition of using diuretics ... normalization of the urinary excretion of alpha-1-microglobulin and an increase in plasma levels of cystatin-C, suggesting that adrenaline aggravates perioperative tubular injury and leads to a decrease in...
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The effects of uncertainty and reputation in sub contracting networks
... firms where they are only big enough such that at the margin, the increase in costs due to diminishing returns of management is equal to the increase in costs incurred in the form of the transaction ... Neither is subcontracting limited to the manufacturing sector International outsourcing in the service industry has been growing since the 1990’s Industry surveys indicate that in 2011, 43% of ... compounded as the number of firms in the supply chain grows As such, the firms in the supply chain face an optimization problem in which they decide the best trade-off between diminishing marginal returns...
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The Duality of Memory and Communication in the Implementation of a Multiprocessor Operating System
... Finally, the kernel informs the hardware physical map module of the new virtual to physical mapping With the exception of the hardware validation, all of these steps are implemented in a machine-independent ... surviving the introduction of new hardware architectures and was never able to efficiently support the large body of UNIX software used within the academic community [16] In addition, from the point ... Mach runs on the majority of workstations and mainframes within the Department of Computer Science, and supports projects in distributed computing and parallel processing such as the Camelot distributed...
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Tài liệu Murray N. Rothbard - History Of Money And Banking In The United States (pdf) pptx
... developing initial hypotheses and testing them in the light of available evidence The initial hypotheses come from the body of economic theory that has evolved in the past 200 years and is being ... anything about the actual content and quality of the actual individuals’ judgments of value Both presuppose that the individuals are valuing and acting, but their theorems are independent of and ... tell us is that in the past definite men or groups of men were valuing and acting in a definite way Whether they will in the future value and act in the same way remains uncertain All that can be...
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... enthalpies of binding and stoichiometries were determined from the binding isotherm by fitting a : binding model to the data using the software provided by the manufacturer Results Reaction of fosfomycin ... chain of K22 participates in fosfomycin binding, thus providing a rationale for the loss of fosfomycin binding to the K22V and K22E mutant proteins However, two other positively charged amino ... replacement of R120 by lysine reduces the probability of forming the fully closed form of the protein The results obtained with the K22V/R120K double mutant protein point toward a central role of arginine...
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IN A PERFECT OCEAN THE STATE OF FISHERIES AND ECOSYSTEMS IN THE NORTH ATLANTIC OCEAN pdf
... fisheries of northern Norway for cod, capelin and other fish appeared to go into decline after the opening of the country’s first whaling station in the 1860s.19 In the early years of the twentieth ... on -the- spot “snapshots” of the abundance of different kinds of marine life there by visitors in the 1500s and 1600s Among them were turtles in “inestimable numbers,” “an in nite number of them ... capelin in the Barents Sea collapsed in the mid-1980s, resulting in the closing of the capelin fishery for five years Iceland’s cod catch fell by about half in 1994 The cod fishery there has since...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
... The motif present in DptF is GLDSV, indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) or leucine (L) in the conserved sequence To determine ... carrier proteins (ACPs) [14,15] The genes dptE and dptF are localized immediately upstream of the NRPSs of A21987C The resulting proteins DptE and DptF were predicted to be involved in the lipidation ... Assay Fig In vitro phosphopantetheinylation of apo-DptF and apoAcpK Coomassie blue-stained SDS–PAGE gel (left) and in- gel fluorescence (right) of the fluoresceinyl-ACP (+) indicates the reaction...
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Báo cáo khoa học: Transcriptome profiling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet pdf
... protein that blocks the processing of sterol regulatory element-binding proteins (SREBPs) by binding to SREBP cleavage-activating protein, thus preventing the latter from escorting SREBPs to the ... regulation, the blocked green lines indicate negative regulation, and the dashed lines indicate indirect inhibition The black lines indicate substance conversion or transportation flow The dashed lines indicate ... Golgi, and negatively regulating sterogenesis The increased expression of Insig2 and the further repression of Hmgcr suggested that endogenous cholesterol synthesis was repressed The upregulation of...
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2009 Investment Company Fact Book 49th edition - A Review of Trends and Activity in the Investment Company Industry pptx
... effects of the crisis in 2008 include the failures of Lehman Brothers Holdings Inc., Washington Mutual, Inc., and a range of other financial institutions; the government-orchestrated rescues of ... Two-thirds of the increase in assets of funds of funds in the past 10 years is attributable to increasing investor interest in lifestyle and lifecycle funds The growing popularity of these funds, ... funds invested in foreign stocks U.S stock and bond funds holding international assets decreased further from the strengthening of the U.S dollar and the resulting decrease in the dollar value of...
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2011 Investment Company Fact Book - A Review of Trends and Activity in the Investment Company Industry doc
... broad overview of the investment landscape by recording in a single volume some of the insights from these meetings and from our own research Sometimes the developments are slow, and the picture ... funds dominated fund investing following the passage of the Investment Company Act of 1940 But successive bear markets in stocks in the 1970s along with rising interest rates drew investors into ... PhD in economics from the University of Michigan and a BS in economics from the University of Wisconsin–Madison Industry and Financial Analysis Sean Collins, Senior Director of Industry and Financial...
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Báo cáo " Characteristics of Quaternary sedimentary facies in relation to water bearing capacity of aquifers and aquicludes in the Red River Delta, Vietnam " ppt
... gray fine clayey sand of lagoonal and coastal swamp facies of Hai Hung Formation in the upper sequence and the fine sediments of deltaic and marine facies of Vinh Phuc Formation in the lower sequence. ... swamp and marine facies (formed in the final stage of each cycle). Based on this point of view, the Quaternary sediments in the Red River Delta can be divided into the following ... plain. It is composed of sand, silt, clay of alluvial facies of Thai Binh Formation (Fig. 2) in the upper part and lens of sand, silt, clay of Hai Hung Formation in the ...
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Cognitive effects of acute tryptophan depletion in the healthy elderly potx
... Depletion minus placebo score great as that seen in the males receiving the lower dose drink In SMTS, the reduction in the females receiving the higher dose was not as great as the increase in the females ... during ATD in females receiving the high dose, there was an increase of greater magnitude in females receiving the low dose Discussion The current analysis is the first to examine the effects of ATD ... those in studies in the young, thereby increasing the variance and making statistical significance less likely The absence of an interaction between age and ATD in this analysis may be explained...
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Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica ppt
... memorize the position of the illuminated windows In 36 subsequent presentations of the house, one of the windows was illuminated and the participant decided whether or not this matched one of the ... on the numeric memory and spatial memory might partly occur via the modulation of dopamine and norepinephrine in prefrontal cortex together with the modulation of acetylcholine and serotonin in ... target digit was randomly selected and constantly displayed to the right of the monitor screen A series of digits was presented in the centre of the screen at the rate of 80 min−1 and the participant...
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Báo cáo khoa học: Murine serum nucleases – contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3) doc
... with h of incubation at 37 °C Chromatin degradation in the serum of a DNase1 KO mouse was accelerated by the addition of aprotinin and the specific inhibitor for the activation of the plasminogen ... activity found in DNase1 KO mice also occurred in WT mice, and was activated by the addition of aprotinin, thereby masking the inhibitory effect of aprotinin on DNase1 ⁄ plasmin-induced chromatolysis ... with plasmin inhibited subsequent chromatolysis, demonstrating that rmDNase1l3 Our finding that the serine protease inhibitor aprotinin and the inhibitor for the activation of the plasminogen system...
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NATIONAL ACTION PLAN for CHILD INJURY PREVENTION: An Agenda to Prevent Injuries and Promote the Safety of Children and Adolescents in the United States pptx
... States with the lowest injury rates are in the northeast • The number of fire and burn deaths is highest in some of the southern states • The number of traffic injuries is highest in some southern ... strategies in their own settings Curricula gaps, staff training, and the need for in- service programs are among the challenges to integrating child injury prevention education and training into existing ... enhancing communications, improving education and training, advancing health systems and health care, and for strengthening policy Elements of the plan can inform actions by cause of injury and...
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