... substitutions imposed on the backbone conformation of WT* shows that the pattern of P37P38P19W45Fig. 1. Ribbon structure modelled onthe X-ray structure of humanubiquitin [32]. The position and ... establish whether the substitutions of P37 and P38 are substantially perturbing the conformation and dynamics in this region ofthe protein,or more specifically, whether st ructural effects are ... erturba-tions andthe pattern of NOEs in the vicinity of the mutation sites. Deviations of Ha signals from random coilchemical shifts pro vide a sensitive probe of local perturba-tions to secondary...
... assayed by varying the concen-tration of Tm in the presence of constant concentration of F-actin and myosin S1. In this condition, Tm inh ibits the ATPase activity as its concentration increases [33]. ... contributions to the understanding of theeffectsof these mutations onthe clinical symptoms of patients carrying cardiomyopathic Tms.Experimental proceduresConstruction of expression plasmids and site-directedmutagenesis The ... stability ofthe protein as a whole, ratherthan onthe position ofthe mutation in the polypeptide chain,as demonstrated by the biophysical assays. Our studies h aveprovided additional contributions...
... interaction B-B - between ions in sublattice B and interaction A-B - between ions of sublattices A and B. We denote λaa, λbb, λab correspond to molecular-field constants of exchange interaction ... frustration arising from the co-existence of competing antiferromagnetic and ferromagnetic interactions. The separation of FC and ZFC curves at low temperatures could be considered that the sample ... lattice constant and volume of unit cell increase with Zn content in the samples due to larger ionic radius of Zn2+ ion (0.82 Å) substituted for Ni2+ ion (0.78 Å). The X-ray density, the real...
... 12B. The effect ofthe presence of the adenylates onthe ability of POR-PChlide640to undergophotoconversion was checked by comparing the efficiency of photoconversion of PLB samples containing ... explanation ofthe acceleration ofthe low-pHdriven spectral changes seen for the photoconverted and nonphotoconverted enzymes on addition ofthe adenylnucleotides or adenosine (Fig. 12) is that these ... during the course of prepar-ation cannot be excluded, but that still leaves unanswered the question of how the addition of micromolar concentra-tions of NADPH suffice to drive the conversion of...
... Surface Transportation Efficiency Act of 1991 iiAbstract The Effectsof Land Use onthe Mobility of Elderly and Disabled and Their Homecare Workers, andtheEffectsof Care on Client Mobility: ... identify the relationship between residential location, the transportation habits and needs of consumers and providers, andthe extent of care consumers received. The six interrelated hypotheses ... traffic analysis zone (TAZ) and zip code. Note. Based on Metropolitan Transportation Commission (MTC) data i The Effectsof Land Use onthe Mobility of Elderly and Disabled and Their Homecare...
... forming the links betweenemissions onthe one hand and exposure andeffectsonthe other hand. The EUROAIRNET information system is developed and maintained by the European Topic Centre on Air ... design and site selection • Selection and evaluation of measurement methods and equipment• Management ofthe laboratory and training of personnel The major components of quality control are:• Controlling ... calibration and analysis methods in laboratory and field conditions;• the participation to ISO and CEN activities for the standardisation of measurement methods;• the organisation of inter-comparisons...
... Sources of Carbon Monoxide 7 Health Effectsof Carbon Monoxide 7 Prenatal Effectsof Carbon Monoxide 8 Airborne Particles 8 The Challenge of Measuring Particle Pollution 8 Sources of Particle Pollution ... The Health Effectsof Air Pollutionon Children Fall 2000 - 1 - Introduction Air pollution has many effectsonthe health of both adults and children. The purpose of this article ... terms ofthe types of cells andthe overall structure ofthe alveolar region. Figure 1 shows a magnified view ofthe structure ofthe normal gas-exchange region of the lung. It is called the...
... at the end of this chapter. These stud-ies contribute to the overall evidence onthe short-term effectsof air pollutionon children’s health and activities. EFFECTS OF AIR POLLUTION ON THE ... PREMATURITY AND INFANT MORTALITY36 EFFECTSOF AIR POLLUTIONON CHILDREN’S HEALTH AND DEVELOPMENT A REVIEW OFTHE EVIDENCEfor the health consequences of ambient air pollution. The ability of DEPs ... detail the role of exposure to air pollution in acute respiratory infections, in the development and manifestation of asthma and allergies, and in the de velopment of lung function. The introductory...
... determine whether the particular effectsof adeninenucleotides or the lack of effect of BKA can be repro-duced. Nonetheless, the present findings, together with the previous report that mitochondria ... for-mation ofthe pore [7,22]. Recent findings excluded the voltage-dependent anion channel (all isoforms) [23],CypD [24–27] and ANT (isoforms 1 and 2) [28] asbeing the constituents ofthe pore ... organisms(lower panel) and superimposed three-dimensional reconstruction ofthe known bovine ANT andthe predicted conformation ofthe ArtemiaANT (upper panel). In the lower panel, every 10...
... Kesler and JM Hausdorffdrafted the manuscript. All authors helped with the inter-pretation ofthe results, reviewed the manuscript and par-ticipated in the editing ofthe final version of the manuscript.AcknowledgementsWe ... workstation for analysis using software thatextracts the initial and end contact time of each stride and determines stride and swing times. To focus onthe assess-ment ofthe dynamics of continuous, ... the gait of older adults with a HLGD and their reliance on vis-ual input, we examined the effect of lighting changes on the gait of older adults with a HLGD and compared theirresponse to that of...
... made substantial contributions to con-ception and design, acquisition of data, and analysis and interpretation ofthe data. MK has been involved in draft-ing the manuscript and revising it critically ... Magnetometric evaluation oftheeffectsof galliumarsenide onthe clearance and relaxation of iron particles.Ind Health 1993, 31:143-153.Journal of Occupational Medicine and Toxicology 2009, ... Ferromagnetic contamination in the lungs and other organs ofthe human body. Science 1973, 180:745-748.5. Nemoto I: A model of magnetization and relaxation of fer-rimagnetic particles in the lung....
... func-tions, and diverse applications [14-17]. 1D materialshave received great attention because of their muchpotential for fundamental studies ofthe roles of dimen-sionality and size on their ... well as for theirapplications in nano-devices [18]. The success of nano-devices similarly trusts onthe ability of controlling the transport and electrical properties ofthe semiconduc-tors, ... p-type conductive ZnO [19], andthe realization of p-typeZnO is rather difficult because of its as ymmetric dopinglimitations [20]. Recently, research of ZnO has beenfocused onthe synthesis of...
... Authors' contributions PJ carried out the experiments, analysis, and writing ofthe manuscript. SE, KP, and TT participated in the conception and design ofthe study. DPC and GR revised the manuscript ... ions substituting the Ti ions (at the B site). Therefore, substitution ofthe Ni ions at the B site may result in breaking the long-range ordering, resulting in a reduction ofthe ferroelectric ... intellectual content. All authors read and approved the final version ofthe manuscript. Acknowledgments This work was supported by the Faculty of Science, Chiang Mai University andthe Office of...