... one (Tait 1880) This statement is now known to be true, due to the proof of the four color theorem by Appel & Haken (1976) [edit] Graphs on nonplanar surfaces In 1969, Branko Grünbaum conjectured ... described by Cole & Hopcroft (2002) and Alon (2004) The algorithm of Alon (2004) begins by making the input graph regular, without increasing its degree or significantly increasing its size, by merging ... algorithm [edit] Additional properties The uniquely 3-colorable generalized Petersen graph G(9,2) One of its three color classes is shown by the light edges and the other two can be found either by rotating...
... cattle database) Both disease detection and criteria for treatment are influenced by human perception, as exemplified by a study of farmers and mastitis [1] This influence introduces the possibility ... disease) The scores are gathered by veterinarians between and 21 days in milk from all cows calving in the herds Medical treatments of metritis are also recorded by the practicing veterinarians, ... motivate the farmer to enhance disease prevention through dialogue with and the advice given by the veterinarian By the end of 2008, approximately 100,000 cows, or approximately 20% of the total Danish...
... β×the average intensity determined by PSS using Equation (4)~(7) Therefore, β can be given by: β= the slope of regression line / the average intensity determined by PSS (11) Table shows the obtained ... particle trajectory calculations can be performed by computational fluid dynamics UV intensity at any point P (r, z) within the reactor is developed by modifying AKEHATA Equation1) as: I(r,z)=Σψ1・ψ2・SL・ΔLn/(π2・ρ3)exp(-[εL(r-r0)+εQ・δQ]ρ/r) ... biodosimetry and CFD model which were simulated by using Equation (3) Biodosimetric RED J/m 300 250 200 150 100 50 0 100 200 300 RED determined by CFD model J/m 3-Lamps 8-Lamps 線形 (**) 4-Lamps...
... (Line 1) and inner (Line 2) bay areas by scuba divers in September 2003 and 2004 These belt transects were divided into six to nine surveyed sections classified by the differences in macrophyte compositions ... loggers (Onset Computer Corporation) over the course of the study Light intensity was measured during noon ± hours Differences in the light intensity between the reefs were analyzed by Tukey’s HSD ... inhabited by U pinnatifida in Line Others indicate the biomass of Ulva sp and Sargassum horneri Fig shows the algal biomass between the artificial buoyed reefs and natural rocky shore inhabited by U...
... STAT pathway activation [19] Whereas transformation by most EGFR mutants confers cell sensitivity to erlotinib and gefitinib, transformation by an exon 20 insertion (D770insNPG) makes cells resistant ... specifically bind to EGFR (including EGF, transforming growth factor-a, amphi- A B Signal transduction by ERBB proteins Binding of a family of specific ligands to the extracellular domain of ERBB (except ... ERBB2, see below) leads to the formation of homodimers and heterodimers This process is mediated by rotation of domains I and II, leading to promotion from a tethered configuration to an extended...
... kinase domain of the receptor and thereby stabilize the interaction with EGF-TKIs signaling cascade, independently of EGFR activation Mutation of KRAS thus bypasses the need for ligand binding ... tyrosine kinase domain of the receptor and thereby stabilize the interaction with EGF-TKIs, leading to an increase of 100-fold in sensitivity to inhibition by EGFR-TKIs compared with that of the wild-type ... FEBS 311 EGFR-targeted anticancer therapy I Okamoto accumulate, an improvement in OS, conferred by treatment with these drugs, is also expected in patients harboring EGFR mutations It was not...
... apoptosis signaling by binding and antagonizing the anti-apoptotic Bcl-2 family members, thereby causing activation of Bax and Bak [23] Regulation of Bcl-2 family members can occur by a number of ... death pathway by directly activating Bax ⁄ Bak [36] Bim expression is regulated by both transcriptional in Fig 2) and post-transcriptional levels (pathway Phosphorylation of Bim by ERK1 ⁄ targets ... gefitinib As the level of p15INK4b is increased by MEK inhibitors, but not by Akt inhibitors, the induction of Fig The cell-cycle is arrested at the G1 phase by TKI-induced CDK inhibitors EGFRTKIs result...
... flexuosa xylanase As determined by SDS/PAGE, the C thermophilum xylanase was present as a 26 kDa protein and the N flexuosa xylanase as 28 kDa Both xylanases were purified by cation exchange chromatography ... CTX, is partly due to movements induced by glycerol binding Therefore, we note that some of the structural differences among family 11 xylanases are caused by ligand binding Both NFX and molecule ... stabilizing mutations found by the early study of Argos et al [40] For thermophilic proteins, the decrease in the frequency of Ser but not the increase of Thr was observed by Kumar et al [38] These...
... the smallholding is usually family-owned, managed by the family head and worked by family labour The plantation in turn is frequently owned by a company or a government enterprise, and usually ... low, yield could be improved by increasing the number of trees per hectare, and by planting better yielding rubber varieties However, expected land scarcity caused by outside land claims provides ... agroforestry systems in Indonesia and Thailand” The project is being financed by the Common Fund for Commodities (CFC) It is coordinated by the World Agroforestry Centre (ICRAF), and research partners include...
... of each CO3-1 was identified as trehalose by TLC as well as by MALDI-TOF MS analysis of the products obtained by permethylation and hydrolysis, and also by 1H-NMR Oligosaccharide CO3-2 appeared ... chromatographed by descending chromatography in the following solvent systems: butan-1-ol/pyridine/0.1 M HCl (5 : : 2, by vol.); propan-2-ol/butan-1-ol/water (140 : 20 : 40, by vol.); propanol/ethyl ... sugars, followed by analysis of the products of these digestions The tetrasaccharide was resistant to hydrolysis by a-glucosidase (Fig 6, lane 5), but was susceptible to digestion by a-galactosidase...
... telephone numbers of cases were provided by WRCC staff Information outlining the study was mailed to each of the referrals and followup telephone calls were made by research personnel to schedule interviews ... 1.00-5.53, for 10 years work) (Table 6, model 4) This metric was motivated by the endocrine disruptor hypothesis and by preliminary findings of an excess in those for whom food manufacturing was ... A, Gilbertson M, Beck M: Farm work in Ontario and breast cancer risk In Rural Women’s health Edited by Leipert BD, Leach B, Thurston W Toronto: University of Toronto Press, In press; 101–121 52...
... analyzed by SDS/PAGE followed by Western blotting, using mAb IG12 and Bo14 for detection of the allergen As can be seen in Fig 3B,D, rPhl p Q showed the appropriate size of 33 kDa and was detected by ... analyzed by dotblotting after removal of small peptides by filtering Natural Phl p pollen allergen as well as E coli-expressed rPhl p 1, both of which not possess proteolytic activity, were bound by ... bound by IG12 In contrast, Pichia expression of mostly inactive rPhl p shows binding of all three antibodies The active rPhl p was tested in zymograms and by affinity purification, followed by elution...
... strongly by younger children than older children This is borne out by the relatively few studies that examined samples containing both infants and older children and differentiated by age in ... as measured by body mass In other settings, the negative effects of energy and other stresses from work may be offset by increased consumption of food or health care made possible by the women’s ... in large numbers Unlike the poorer women hit by recession in the 18 Elson (1995) summarizes a number of these studies See also the volume edited by Benería and Feldman (1992) 19 In addition,...
... soil by phosphate and Cd in potato tubers ŽMcLaughlin et al., 1994; Tiller et al., 1997 Fertilizer Cd content had no effect on Cd uptake by tubers even though Cd content in fertilizers differed by ... hay1 yry1 P-fertilizers increased the soil concentration by to 6.8 g Cd hay1 yry1 In the FYM-treated plots, cadmium increased, on average, by 3.2 g Cd hay1 yry1 Concerning the large scale pollution ... Changes in agricultural systems may significantly affect the buffering of a contaminant by soil Cd adsorption by clay, iron and manganese oxides, and organic matter decreases with decreasing pH ŽAlloway,...
... presence of ATP The in vitro chromatin assembly carried out by cellular ⁄ nuclear extracts, giving uniformly spaced nucleosomes, is affected by parameters such as ionic strength, concentration of ... generated by using the same primer (D) A comparison of the profiles of lanes and 13 in (C) is shown Protection of 145 bp due to a positioned nucleosome + overlaps with part of L3 occupied by R3 2400 ... possibility that R3 at L3 was removed by nucleosome + 1, a total protection size of more than 145 bp DNA downstream of L2 and spanning over L3 suggests that it was generated by the cooccupancy of R3 and...
... typically not bound by the same rules everyone else is bound by Neo learns to hack the Matrix, bending its enforced reality to his will, and eventually comes to it better than anyone else By the end of ... though In both stories they are aided by different and distinct characters at critical and life threatening moments Luke is on the verge of being shot down by Darth Vader, just before he destroys ... just before he destroys the Death Star, when he is saved by a shot from Han Solo in his Millennium Falcon Neo is keep from being killed by an agent, when Trinity shots the agent in the head At...