... s
xpressing WT
MLPC for 2 w
e
or : target ratio
inistration of W
hs. Although
pe bcr-abl pep
patients treat
peptides, they
capable of kil
any clear clini
mmune respon
on for patien
ation for AM
and MDS ... cells.
ous B-LCL
led B-LCL
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l antibody
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Int. J. Med. Sc
Figure 2. WT
performed in a
the 20th admi
PE-modified-t
y
for WT1 pept
peptide/MHC
3. Kinetics o
Comple
blood ...
The present study showed that WT1 peptide
vaccination for imatinib-pretreated CML patients is
feasible and presumed to be effective for reducing
leukemia cells, which was supported by the...
...
Vitamin D deficiency is extremely common in patients with all types of cancer.
Why are Cancer Patients at Risk for Vitamin D Deficiency?
Cancer patients may spend less time in the sun because ... measures the form of vitamin D called 25-hydroxyvitamin D.
Cancer patients should ask their doctor whether or not they have had their blood tested for
25-hydroxyvitamin D.
Patients should ... D deficiency (pages 4 & 5).
Why are cancer patients at risk for vitamin D deficiency?
Why is sufficient vitamin D important for cancer patients?
Identifying vitamin D levels
Maintaining...
... evaluated our QA system for
IMRT plans that are going to be used to treat patients
with GBM brain tumors. Presently, we perform rou-
tine QA measurements for each IMRT patient either
immediately ... this study was to evaluate the significance of performing patient specification
quality assurance for patients diagnosed with glioblastoma multiforme treated with in-
tensity modulated radiation ... TX) to check
independent monitor units (MU) for each beam. Pre-
treatment IMRT plans for ten patients diagnosed with
GBM brain tumors were selected. For each of the ten
pretreatment plans, verification...
... therapy for ischemic stroke patients with APS
based on the strict Sydney criteria [5]. One reason may
be that patients with stroke complicated with APS are
rather rare compared with patients ... of antiplatelet and anticoagulation therapy for
secondary prevention in ischemic stroke patients with APS.
The subjects were 20 ischemic stroke patients with antiphospholipid antibody, 13 with ... stroke in patients without as-
sociated aPL. The patients in our study were selected
according to the Sydney criteria [5] of APS and the
average age was consistent with that in typical APS
patients....
... VE needs significant less time
and, therefore, can be expected to reach a higher com-
pliance in previously inactive patients. Unfortunately,
rare information exists about the metabolic conse-
quences ... control group (flexibility training) on glycemic control
in type 2 diabetes patients. Forty adult non-insulin dependent patients participated in the intervention. Fasting
glucose concentration, ... Measures
Before and three to four days after the training
period, subjects entered the laboratory after 12 h fast-
ing and an oral glucose tolerance test was performed.
Time of drug ingestion...
... (±16.5) for the whole study group, 62
(±15.3) for AVNRT, 48 (±17.6) for AVRT and 63 (±13.3)
for EAT. With respect to the underlying tachycardia,
66.9% of patients with AVNRT, 75% of patients ... 305 patients (99.0%) had specific symptoms.
The main reasons for patients seeking therapy were
tachycardic palpitations (281 patients, 91.5%) and
increasing incidence of episodes (224 patients, ... value.
For reasons of structure and to simplify an-
swering for the patients we divided the questionnaire
in three different blocks: the first block was related to
the situation for the patients...
... Moreover, patients with exac-
erbation but not patients with stable disease were in-
vestigated. Inhalation with fucose/galactose has never
been used before in a clinical trial with CF patients. For ... stated.
RESULTS
Patient characteristics
A total number of 11 patients (8 male, 3 female,
median age 27 years) were included. 4 patients were
treated with inhalation only, 7 patients received ... aeruginosa in CF patients
is a novel therapeutic approach that has never been
performed previously. However, the main weakness
of the present study is the small numbers of patients
studied...
... docu-
mented variations in health outcomes
for chronically ill patients that cannot
be explained in terms of measurement
error. For elderly Medicare patients and
for poor patients, variations in outcomes
during ... better (P<.05) for elderly
patients in HMOs relative to FFS but not in 2 other sites. For patients differing in
poverty status, opposite patterns of physical health (P<.05) and for mental health
(
P<.001) ... base-
line for patients sampled from HMO and
FFS systems (Table 3). In relation to pub-
lished norms for the US general popula-
tion," MOS patients scored at the 24th
and 35th percentiles for physical...
... consideration. See the answer/enrollment form after the article for additional information
regarding the program.
Readability and Patient
Education Materials Used for
Low-Income Populations
MEG WILSON, ... was used
for this study. Providers were asked to submit written
PEMs used most frequently for their clients. Inclusion
criteria were that materials were in English and written
format. Patient ... health
education information.
15,16,18,25
Readability is determined
for these measures through analysis of word and sentence
difficulty in running text. Scores for SMOG and Flesch-
Kincaid are calculated for...
... mean patient volumes ⁄ province for the five previ-
ous quarters (HMIS 2006). Eligible participants were
patients aged ‡5 years with respiratory symptoms able to
provide consent or assent (for ... followed for sputum sampling. Sus-
pected cases had sputum smears taken by clinic staff daily
for 3 days. Three sets were prepared: one for testing at the
clinic facility laboratory, one for staining ... prevalence
of respiratory symptoms among patients over 5 years of
age (World Health Organization 2004) and attendance for
the 24 clinics; a sample size of 1500 patients was sufficient
to detect at...
... primary FDA-related function of
ASD(HA) for CBW defense is to determine the medical indications of
use, both for licensed drugs and IND-classified drugs. Therefore, we
conclude that Health Affairs ... for the today’s CBER. Bio-
logics are regulated under both the PHSA and the FFDCA; they are
classified as drugs under FFDCA for regulatory purposes.
Preclinical testing is required before a drug ... are essential to
the acquisition of drugs and biologicals for CBW defense: licensing
drugs and biologics for military uses, especially CBW defense; using
drugs and biologics classified by FDA...
... responsible for the most severe form of the disease and this par-
asite is developing resistance to the major antimalarial drugs. Therefore, in
order to control malaria it is necessary to identify new drug ... prefers a fork-like substrate for its
unwinding activity [18].
Helicases as drug and therapeutic
target
Resistance to the most efficient, reasonably priced and
safe antimalarials has called for the ... cel-
lular RNA helicases as antiviral targets. Nat Rev Drug
Discov 4, 845–853.
27 Frick DN (2003) Helicases as antiviral drug targets.
Drug News Persp 16, 355–362.
28 Frick DN & Lam AM (2006)...
... the conformational alteration
(reviewed in [27,28]). The low-affinity conformation of
drug binding sites in ABC multidrug efflux pumps is
assumed to correspond to the outward-facing confor-
mation. ... ideal for the mediation of drug binding
site reorientation, although the binding data cannot
unequivocally inform on the orientation of the sites,
only their affinity for interaction with drugs.
The ... interconnected drug binding
sites. The present investigation examines the coupling of drug binding to
ATP hydrolysis. Initial drug binding to the protein requires a high-affinity
interaction with the drug...