discuss the role of a security manager in an organization
Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphataseKonstantinos Mavromatis1,*, Iason Tsigos2,*, Maria Tzanodaskalaki2, Michael Kokkinidis1,3and Vassilis ... the aromatic ring of Tyr269, and theseunfavorable interactions could lead to a decrease of localflexibility and an increased E a value. The validity of the above interpretation was furtherreinforced ... exhibits an E a almost the same as in the caseofthenativeenzyme(Table1).Thermal inactivation of mutant and wild-type enzymes In order to investigate the effects of mutations on the stability of psychrophilic...
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Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf
... state may bemaintained mainly by key amino acids. In this study, two point-mutatedproteins each with a single base substitution [alanine for tryptophan(W14 0A) and alanine for lysine (K13 3A) ] and ... the mutants without tryptophan at 140(W14 0A and W140O) was much lower than both the wild-type protein and mutants E142O and K13 3A. Thermal analysis of protein unfolding The DSC curves of the wild-type ... investigated. Two point-mutated proteins, with a singlebase substitution of alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) , and two truncatedfragment proteins, with fragments...
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A Single-Molecule Perspective on the Role of Solvent Hydrogen Bonds in Protein Folding and Chemical Reactions pptx
... rupture of a pair of hydrogenbonds in the A and B b-strands near the amino terminus of the protein domain causes an initial extension of the protein,before the unfolding transition state is reached.[53] The ... be-tween the first amino acid of strand A (Y9) and the last amino acid of strand G (K87) . The elongation of the x(Y9)Àx(87) distance up to the transi-tion state is defined as the distance Dx A ÀG. ... b-strands. In Figure 5 B, we define the pulling coor-dinate for the A and G b-strands as the distance between the first amino acid of strand A (Y9) and the last amino acid of strand G (K87)....
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Tài liệu The Role of Public Regional Universities in Community and Economic Development doc
... average, command a significantly higher salary ($42,000 annually vs. $28,000 in average annual salary)Preserving ValueContinuing education is important to preserving the market value of specialized ... knowledge and forming intellectual capitalNearly two-thirds of National Association of State Universities and Land-Grant Colleges (NASULGC) have research parks or business incubators (PASSHE has ... Programs and InitiativesBusiness accelerators and/or entrepreneurial initiativesLinking teaching and research to business opportunitiesCollaboration with local business and industrySmall Business...
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Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding affinity pptx
... (5Â-GGCAACAACCTACACTGGTATCAACAAAAAYMGSRCRAATCTCCTCRGCTCCTGRTCWAKTATGCTTCCCAGTCCATCTCT-3Â) and g7EcoFor(5Â-AGTGAATTCTCATCTTTGACCCCCAGCGATTATACCAA-3Â). As a linker to connect these two, a DNAencoding ... To insert tHP downstream of the ORFs, tHP4 andtHP7 (5Â-AATTGGTACCCGATAAAAGCGGCTTCCTGAC-3Â), as well as tHP2 and tHP8 (5Â-AATTGAGGTGGGCTGCAAAACAAAACGGCCT-3Â), were annealedand ligated to the ... types of mutants were also observed.SPR analysis of antigen-binding affinityFor the quantitative evaluation of the H39 mutation,kinetic analysis for antigen–Fv interaction of the wild-type and...
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Báo cáo khoa học: "The Role of Lexico-Semantic Feedback in Open-Domain Textual Question-Answering" ppt
... semantic The Role of Lexico-Semantic Feedback in Open-Domain TextualQuestion-AnsweringSanda Harabagiu, Dan MoldovanMarius Pasáca, Rada Mihalcea, Mihai Surdeanu,Razvan Bunescu, Roxana Grju, ... if (a) a vol-cano IS -A mountain; (b) lava IS-PART of vol-cano, and moreover it is a part coming from the inside; and (c) fragments of lava have all the prop-erties of lava, the following question ... WordNet: A Lexical Database. Commu-nication of the ACM, vol 38: No11, pages 39–41, Novem-ber 1995.Dan Moldovan, Sanda Harabagiu, Marius Pasáca, RadaMihalcea, Richard Goodrum, Roxana Grju and VasileRus....
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Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc
... revealed that the G-10L mutantprotein is routed to the SecYEG translocon via the SRPpathway, the targeting pathway that is exploited by integralinner-membrane proteins. Together, these data indicatethat ... Bioscience (Maarsen, the Netherlands).Bacterial strains The E. coli K-12strainsusedinthisstudyarelistedinTable 1. Strains CE1514 and CE1515 were obtained by P1transduction using strain CE1224 as the ... understandable, as the SecB-bindingsites, which are located in the mature domain of the PhoEprecursor [3], are not affected in the G-10L mutantprecursor. Thus, in the absence of SRP, SecB can targetthe...
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Báo cáo " THE ROLE OF GIFT RECIPIENT PERCEPTION IN CHANGING BRAND ATTITUDES AND GIVER - RECIPIENT RELATIONSHIP " potx
... instrumental in maintaining social ties and serves as a mean of symbolic communication in social relationship. Most of the researches before and after the appearance of Sherry’s model in 1983 can ... brand attitude. It is the primitive assumption of balance theory that unbalanced triads tend toward balance. Although balance theory help to explain the change in recipient’s post brand attitudes ... have positive brand attitudes, then the triad is said to be unbalance. In this example, balance could be attained if the receiver changes to dislike the giver or having post favorable brand...
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Báo cáo khoa học: The antagonistic effect of hydroxyl radical on the development of a hypersensitive response in tobacco pot
... suppres-sion. After in ltration, the treated plants were placed in the light,and the HR extent was evaluated by the ion leakage ratio at 12and 48 h after in ltration. Mean values ± standard error of threereplicates ... Key Laboratory of Monitoring and Management of Crop Diseases and Pest Insects, Ministry of Agricuture of R. P. China, Department of Plant Pathology, College of Plant Protection, Nanjing Agricultural ... with ABA or H2O,ParA1 and the spin trapping assay reagent were coinfiltrat-ed into the leaves, and the plants were placed under light.After 6 h, the levels of OHã in the leaf tissues obtainedfrom...
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The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf
... savings may increase the means to afford college. The other effect is indirect and mainly attitudinal. Having savings over a period of years may raise a young person’s educational expectations ... to increase youth account ownership and savings may play an important role in helping to restore the American Dream of attending college. Because this research finding has simple, doable, and ... importance of youth savings for understanding college attendance. Conclusion Findings from this study suggest that factors other than desire and ability play an important role in determining...
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Báo cáo khoa học: The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism pdf
... and the nuclear ⁄ cytoplasmic ratio was analysed from the Gray images using Lucia G ⁄ F Analysis Software [6].Data analysisResults are presented as mean ± SE for the number of hepatocyte preparations ... were washed in NaCl ⁄ Pi, fixed in 4% (w ⁄ v) paraformaldehyde in NaCl ⁄ Piand stained for glu-cokinase with a rabbit IgG against human glucokinase:318–405 (H88, sc-7908; Santa Cruz) and fluorescein ... h and3 h incubations, and the cell content of Glc6P and the activ-ity of phosphorylase were also similar after 1 h and 3 h.Metabolite and enzyme assaysGlc6P and Fru2,6P2were determined as...
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