diet epigenetics and colonic fermentation and their role in colorectal cancer

Bioactive Foods and Extracts ppt

Ngày tải lên : 14/03/2014, 10:20

... daily intake of glucobrassicin and neoglucobrassicin (the two main dietary indole glucosinolates) was 22.5 mg per day in the United Kingdom 5.5 mg in Denmark, and 2.8 mg in Finland (IARC, 2004) In ... isothiocyanates in plant–insect interactions and in studies examining biological interactions As a result of the vast information relating glucosinolates and healthy properties, there is an increasing market ... glucoiberin (3-methylsulfinilpropyl) and most contain substantial amounts of sinigrin (2-propenyl) For example, sinigrin, glucobrassicin, and glucoiberin have been identified as the major glucosinolates...

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Báo cáo khoa học: "Clostridium septicum sepsis and colorectal cancer - a reminder" pptx

Ngày tải lên : 09/08/2014, 04:21

... benzylpenicillin and 500 mg of metronidazole were administered intravenously and gentamicin was discontinued following microbiology advice Intra operatively, a bulky inflammatory mass was identified in ... Fainstein V, Elting LS: Clostridial bacteremia in cancer patients A 12-year experience Cancer 1991, 61:1928-1942 Furste W, Dolor MC, Rothstein LB, Vest GR: Carcinoma of the large intestine and ... (neutrophilia) and an elevated CRP Urine microscopy revealed white cells and culture confirmed an E coli urinary tract infection She was treated initially with intravenous gentamicin, benzyl penicillin and...

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báo cáo khoa học: "Effective interventions to facilitate the uptake of breast, cervical and colorectal cancer screening: An implementation guideline." pps

Ngày tải lên : 10/08/2014, 11:20

... using a five-point scale targeting the quality of guideline (higher scores indicating better quality) and their intention to use a guideline of this quality (higher scores indicating greater intention) ... efficacy of tailored print materials in promoting colorectal cancer screening: results from a randomized trial involving callers to the National Cancer Institute's Cancer Information Service J ... cancer screening by individuals, specifically for breast, cervical, and CRCs? Interventions of interest include: Population-based interventions aimed to increase the demand for cancer screening,...

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Báo cáo khoa hoc:"Polymorphisms within inflammatory genes and colorectal cancer" doc

Ngày tải lên : 11/08/2014, 08:20

... expression in human colorectal adenomas and adenocarcinomas Gastroenterology 1994, 107:1183-1188 Itzkowitz SH, Yio X: Inflammation and cancer IV Colorectal cancer in inflammatory bowel disease: the role ... (nNOS), and inducible NOS (iNOS) NOS2A is the encoding gene for the inducible NOS It is required for the signalling process in the innate immunity [17] and it plays a central role on chronic inflammatory ... Winkler JD: The codependence of angiogenesis and chronic inflammation FASEB J 1997, 11:457-465 Moore MA: Cytokine and chemokine networks influencing stem cell proliferation, differentiation, and...

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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"

Ngày tải lên : 25/10/2012, 11:18

... http://www.medsci.org Int J Med Sci 2011, 41 Table Serum samples used in training and testing sets MALDI-TOF MS Samples Colorectal cancer Healthy volunteers Total Following binding and washing, the bound proteins ... approaches in colon cancer: promising tools for new cancer markers and drug target discovery Clin Colorectal Cancer 2005; 4(6):396-402 35 Cho WC Research progress in SELDI-TOF MS and its clinical ... laser intensity (200), and sensitivity (9) Mass calibration was performed using an all -in- one peptide reference standard which contained vasopressin (1084.2Da), somatostatin (1637.9Da), bovine insulin...

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Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx

Ngày tải lên : 14/02/2014, 22:20

... Clinical need and practice 2.1 Colorectal cancer is a malignant neoplasm arising from the lining (mucosa) of the large intestine (colon and rectum) Colorectal cancer is the third most common cancer ... following failure of an irinotecan-containing regimen or as a subsequent-line treatment following failure of both irinotecan- and oxaliplatincontaining regimens The Committee recognised that in ... cancer in the UK, with approximately 30,000 new cases registered in England and Wales in 2002 This represents 12% of all new cancer cases in women and 14% of all new cancer cases in men The incidence...

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Nutrition and cancer: A review of the evidence for an anti-cancer diet pptx

Ngày tải lên : 06/03/2014, 02:21

... contribute to hyperinsulinemia, such as refined sugar, foods containing refined sugar, and refined flour products should be avoided and eliminated from a cancer protective diet Low Fiber Unrefined plant ... blood glucose and insulin, body size, and incident colorectal cancer J Natl Cancer Inst 1999, 91:1147-1154 Colangelo LA, Gapstur SM, Gann PH, Dyer AR, Liu K: Colorectal cancer mortality and factors ... eggs, and meat all have this in common – they contain no fiber Refined grain products also have most of the dietary fiber removed from them So, a diet high in animal products and refined grains...

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American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention doc

Ngày tải lên : 06/03/2014, 02:21

... Moderate intensity Exercise and leisure Vigorous intensity Walking, dancing, leisurely bicycling, ice and roller skating, horseback riding, canoeing, yoga Jogging or running, fast bicycling, circuit ... guidelines for regular colorectal screening because finding and removing polyps in the colon can help prevent colorectal cancer Endometrial (uterine) cancer There is strong evidence of a link ... men Having more belly fat (that is, a larger waistline) has also been linked to colorectal cancer Overall, diets that are high in vegetables, fruits, and whole grains (and low in red and processed...

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Báo cáo khoa học: MicroRNA-143 reduces viability and increases sensitivity to 5-ﬂuorouracil in HCT116 human colorectal cancer cells potx

Ngày tải lên : 07/03/2014, 00:20

... signalling In turn, this may constitute a key event for colon cancer onset and progression miR-143 expression was evaluated in situ in mouse colonic epithelial crypts [27] and found mainly in the ... levels in cancer and, in particular in colon cancer, may be an important factor contributing to tumour growth and ⁄ or escape from apoptosis In addition, miR-143 expression has been shown to increase ... a-mangostin exposure in human colon cancer DLD-1 cells, resulting in increased apoptosis [31] Furthermore, a-mangostin acted synergistically with low dose 5-FU, increasing DLD-1 growth inhibition...

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Esophageal Cancer – Cell and Molecular Biology, Biomarkers, Nutrition and Treatment Edited by Ferdous Rastgar Jazii Published pdf

Ngày tải lên : 08/03/2014, 00:20

... an intrinsic tyrosine kinase activity, or by forming a complex with an intracellular tyrosine kinase [9] Following to binding of growth factors to their corresponding receptors the tyrosine kinase ... The role of insulin-like growth factor and insulin-like growth factor binding protein in human esophageal cancer Anticancer Res 2004; 24: 3029 –3034 [56] Heldin, C.H., A Ostman, and L Ronnstrand, ... Biomarkers, Nutrition and Treatment In addition to its role in Wnt signaling, β-catenin is also involved in cell adhesion, providing a link between actin cytoskeleton and cadherin(s) cell adhesion...

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Diet, nutrition and the prevention of cancer ppt

Ngày tải lên : 15/03/2014, 01:20

... overweight/obesity, limiting alcohol intake and increasing physical activity will reduce cancer risk, as will limiting consumption of Chinese-style salted ﬁsh and minimising dietary exposure to aﬂatoxin in populations ... these dietary factors are important Risk will probably be decreased by increasing the average intake of fruits and Diet, nutrition and cancer Table Diet, nutrition and cancer: recommendations Maintain ... Stattin P, Bylund A, Rinaldi S, et al Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins and prostate cancer risk: a prospective study Journal of the National Cancer...

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Nutrition and Physical Activity Guidelines for Gynecological Cancer Survivors ppt

Ngày tải lên : 22/03/2014, 11:20

... carrots and in dark green leafy vegetables Eating carrots has been shown to play a role in decreasing risk of cervical cancer To reap the most rewards of eating fruits and vegetables, eat them in their ... low-fat, high protein alternative to meat Starchy vegetables like potato, yam, and cassava are also included in a plant-based diet as are nuts and seeds Nuts and seeds provide protein and heart-health ... • • Overweight and obesity increase the risk of certain cancers amongst other common chronic diseases Risk of endometrial cancer increases with increased body fatness and abdominal fatness So,...

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Nutrition, Exercise and Prostate Cancer potx

Ngày tải lên : 22/03/2014, 16:21

... exercise Key Points to Remember Avoiding muscle loss and/ or gaining muscle through increased protein intake and exercise can help in achieving and maintaining a healthy body weight Increase intake of ... for cancer and stimulates production of insulin, which is linked to an increased risk of diabetes, heart disease, and prostate cancer Cutting back on sugar intake, maintaining a healthy diet, and ... prostate cancer, including heart disease and diabetes 18 Building Strong Muscles Avoiding the muscle loss common in aging, inactivity, and hormonal therapies and/ or gaining muscle through increased...

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Classiﬁcation of colorectal cancer based on correlation of clinical, morphological and molecular features doc

Ngày tải lên : 22/03/2014, 17:20

... uniform and linear sequence of steps, with APC inactivation initiating adenomas and additional genetic changes, notably KRAS mutation, and TP53 inactivation promoting the emergence of increasingly ... oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front Pathol Res Pract 1998; 194; 701– 704 Kirchner T, Brabletz T Patterning and nuclear b-catenin expression in ... Risk of colorectal cancer in adenoma-bearing individuals within a deﬁned population Int J Cancer 1986; 38; 173–176 Jass JR, Stewart SM Evolution of hereditary non-polyposis colorectal cancer Gut...

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colorectal cancer, methods and protocols

Ngày tải lên : 10/04/2014, 22:22

... for 30 s Continue from step in Subheading 3.2 3.4 Staining of FFPE Histologic Sections for LCM (DNA Isolation) Perform steps 1–7 in Subheading 3.2 After staining in eosin, rinse in a 95% ethanol ... Localization of intestinal interleukin activity and protein and gene expression to lamina propria cells Gastroenterology 104, 749–758 Strong, S A., Pizarro, T T., Klein, J S., Cominelli, F., and Fiocchi, ... carcinomas and colorectal carcinomas, gains in chromosome 13 were not a frequent finding in gastric carcinomas (8,9,13) Gastric carcinomas from patients with hereditary nonpolyposis colorectal cancer...

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Báo cáo hóa học: " Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients" docx

Ngày tải lên : 18/06/2014, 16:20

... carcinoma patients, unaffected colonic mucosa, carcinoma tissue) one has to keep in mind the differences in sample sizes and applied tests The highly significant difference in CD between blood and ... antigens and prognosis in colorectal cancer patients J Transl Med 2005, 3:3 Ropponen KM, Eskelinen MJ, Lipponen PK, Alhava E, Kosma VM: Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal ... origin, we found a negative correlation between HAC/PBGD and CD (Figure 3) as well as HAC/PBGD and n(F) (not shown) However, separate analysis of the samples originating from blood and originating...

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Báo cáo hóa học: " LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer" pptx

Ngày tải lên : 18/06/2014, 16:20

... LEF-1 and TCF4 expression in colorectal cancer To investigate the localisation of LEF-1 and TCF4 in human colorectal cancer, we evaluated the expression of these proteins by immunostaining on ... These surprising findings suggest that TCF4 might be the main binding partner for b-catenin during development and progression of colorectal cancer whereas an enhancement of Wnt/bcatenin transcriptional ... exclusive in colorectal cancer In accordance with published literature we found nuclear b-catenin positivity in 75% of cases In contrast LEF-1 expression was found only in 26% and TCF4 in 46% of colorectal...

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Báo cáo sinh học: "Clinical outcomes of active specific immunotherapy in advanced colorectal cancer and suspected minimal residual colorectal cancer: a meta-analysis and system review" pdf

Ngày tải lên : 18/06/2014, 19:20

... Medline and PubMed from January 1998 to January 2010 for original studies on ASI in CRC, Using the following keywords: colorectal OR “colon” OR “rectal” AND cancer OR “carcinoma” AND vaccine ... D, Thiel E: Clinical and Immunologic Responses to Active Specific Cancer Vaccines in Human Colorectal Cancer Clin Cancer Res 2006, 12:3064-3069 14 Alejandro R, Jadad MD, DPhil R, Andrew Moore ... 42 43 in advanced cancer patients of a diversified prime -and- boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic...

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Báo cáo sinh học: "Protein kinase CK2a is overexpressed in colorectal cancer and modulates cell proliferation and invasion via regulating EMT-related genes" docx

Ngày tải lên : 18/06/2014, 19:20

... [18] In the present study, we assessed CK2a expression in colorectal cancer, adenoma, and normal colorectal epithelium and found CK2a involvement in CRC tumorigenesis Moreover, the role of CK2a in ... The human colorectal cancer cell lines LoVo, SW480, HT29, HCT116 and LS174T were maintained in RPMI 1640 (Gibco, Grand Island, NY, USA) supplemented with 10% fetal bovine serum at 37°C in a 5% ... in colorectal cancer CK2a protein expression was analyzed in 144 patients (104 with CRC and 40 with colorectal adenoma) Staining for CK2a was nearly negative in all of the normal Page of 11 colorectal...

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Báo cáo lâm nghiệp: "Photosynthesis and growth of present New Zealand forest trees relate to ancient climates" ppt

Ngày tải lên : 09/08/2014, 04:20

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