development sustained cognitive deficits and alterations in structure and function of the brain and the hpa a

Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

Ngày tải lên : 14/02/2014, 19:20

... FERM and PDZ-domain-containing (FRMPD2) [8] and Ras guanine exchange factor (RasGEF) veryKIND (v-KIND, or kinase noncatalytic C-lobe domain containing 1) [9] The KIND domain in these proteins ... determinants of the protein–protein interaction between v-KIND and MAP2 (i.e the MAP2-binding core module in v-KIND and the v-KIND-binding core module in MAP2) across a range of amino acid residues, and ... indicated that the RasGEF activity of v-KIND induces the phosphorylation of MAP2 by JNK1 and ⁄ or ERK via the activation of the Ras–Raf–MAP kinase pathway [12] These results appear to be in agreement...

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The graphs below show the numbers of male and female workers in 1975 and 1995 in several employment sectors of the republic of Freedonia

Ngày tải lên : 04/10/2012, 10:02

... at around 700 000 Women also made gains in both the finance/banking industries and in the defence-related public sector Whereas some 125 000 women worked in finance and banking institutions in ... wholesale and retail trade sector, where the number of women rose from about 550 000 in 1975 to almost 800 000 two decades later The number of men in this sector remained stable over the period, at ... men and 250 000 women worked in the communications sector Twenty years later, though the number of men remained unchanged, the number of women rose to 550 000 A similar situation was seen in the...

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Motivation in learning english speaking of the second year tourism major students at tourism and foreign language department, sao do college of industry

Ngày tải lên : 07/11/2012, 15:01

... well as the scope of the study Chapter two displays the background of motivation and speaking teaching In the chapter, the main approaches to motivation and de-motivation in foreign language teaching ... guidance and practice in both transactional and interactional speaking Interactional speech is communicating with, someone for social purposes It includes both establishing and maintaining social ... formal and sociolinguistic aspects of a language with adequate proficiency to communicate 16 CLT is usually characterized as a broad approach to teaching, rather than as a teaching method with a...

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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

Ngày tải lên : 06/03/2014, 09:22

... representing the proHP8Xa zymogen, a truncated form of proHP8Xa and the catalytic domain of active HP8 are marked with arrowheads The size and position of molecular weight standards are indicated on the ... ¨ 3¢-RACE and 5¢-RACE to obtain the missing ends of the cDNA, and then used primers encompassing the start and stop codons, with larval fat body cDNA as template, to obtain eight individual clones ... gene In the clade including Spatzle-1, the branch lengths are noticeably longer and ¨ the bootstrap values are lower than in the other clades containing Spatzle-2 to Spatzle-6, indicating a lower...

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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf

Ngày tải lên : 06/03/2014, 11:20

... between the minidomain and the zinc-binding domain of the zinc ﬁnger protein Ynr046w [25] (Fig 8) The ﬁt of the heavy atoms (Ca, C, and N) from three b-strands and the a- helices of both the closed and ... HN and the Ca signal of the preceding amino acid, correlating the amide NH with the Ca and Cb signals, correlating the amide NH with the Ca and Cb signals of the preceding amino acid, a threedimensional ... were obtained for more than 99% of the 1H, 13C and 15N atoms of the protein backbone, and for more than 78% of the side chain atoms The main set of backbone u and w dihedral angles was calculated...

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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Ngày tải lên : 08/03/2014, 10:20

... Mansouri and Winterhalter [5] reported that the oxidation of the a chains of Hb A0 was 10 times faster than that of the beta chains and that the oxidation of the beta chains was not in uenced by pH The ... presence of EDTA The rough S minnesota LPS increased the initial fast phase of the reaction, but decreased the rate of the slow phase of oxidation in the presence of EDTA A comparison of rough and ... during the auto-oxidation of Hb In general, the increase in the oxidation rate of crosslinked Hb mediated by LPSs is due to an increase in the rate of the initial fast phase, i.e oxidation of the a...

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Báo cáo khoa học: 2-Oxo acid dehydrogenase complexes in redox regulation Role of the lipoate residues and thioredoxin pot

Ngày tải lên : 17/03/2014, 09:20

... the physiological advantage of the E2 with the three lipoyl domains cannot be ascribed entirely to the catalytic role of these domains Rather, the advantage appears to depend on the ability of ... mechanism of redox regulation The concentrations of 2-oxoglutarate and CoA determined in mitochondria [45] are saturating for the complex, while NADH/NAD+ ratio varies depending on the metabolic state ... sensitivity of the mitochondrial complexes to the 2-oxo acid, CoA-induced inactivation, as the thioredoxin effect is related to alleviation of this inactivation On the other hand, among 11 thioredoxin...

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Báo cáo khoa học: Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2 pdf

Ngày tải lên : 30/03/2014, 10:20

... protein, indicating that the mutation affected the catalytic machinery directly, rather than the oligomeric state of the enzyme Overall structure The variation in size and the observed amino acid ... via the catechol and protocatechuate branches of the 3-oxoadipate pathway [1,2] In the protocatechuate branch of the 3-oxoadipate pathway, protocatechuate is initially oxygenolytically cleaved ... (chain B) and orange (chain D) Residues are labeled according to the ArCMLE1 sequence Hydrogen bonds of active site arginines (Arg155 and Arg312) are indicated by dashed lines The side chain of...

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structure and function of the arabic verb

Ngày tải lên : 03/04/2014, 12:48

... ʕuquudin qaadimaat, pp 11–15 (SA#3) by Madanii ʕabbaas ɦ aa∆aati an-nidaam at-tarbawii ʔ ilaa al-ʔ islaaɦ, pp 33–37 (SA#4) by ɦi∆aazii Mu∆aahid ɦ awla a daadi al-muhaa∆iriina al-yahuud as-sufyaat ʔ ... classified as follows: (SA#l) by Driss Ridha a li mustaqbalin li-nadwati al-mustaqbali al-ʔ islaamii, pp 5–10 (SA#2) by Turaabii Hasan ʔawlawiyyaat at-tayyaari al-ʔ islaamii li-␪alaa a ʕuquudin ... ilaa falastiin, pp 65–70; and the fifth (SA#5) from Al-ma∆alla al-masriyya li-ddiraasaati an-nafsiyyati of September 1991 by Yuusuf ∆um a Sayyid tartiib a daa␪i al-ɦayaati al-mu␪iirati li-l-mamaqqati,...

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nanotechnology in medical applications state of the art in materials and devices

Ngày tải lên : 28/05/2014, 14:35

... disappears, diminishes, or at least stops growing Thermotherapy can be applied as stand-alone therapy, i.e thermal ablation, or as adjuvant therapy enhancing the efficacy of chemotherapy and/ or ... feature of nanoporous materials is the increase of surface area of the material In general, surface area increase of nanoporous materials improves catalytic, absorbent and adsorbent properties Adsorbing ... advantage of using smaller particles is that they can be inserted into any part of the human body to treat cancer cells in their infancy The biocompatibility of silica and gold at the nanoscale has...

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Báo cáo khoa học: " Prevalence of Giardia intestinalis and other zoonotic intestinal parasites in private household dogs of the Hachinohe area in Aomori prefecture, Japan in 1997, 2002 and 2007" potx

Ngày tải lên : 07/08/2014, 23:22

... dogs had decreased compared to 10 years ago, since the knowledge of owners regarding canine intestinal parasites and parasitic zoonoses has been increased provably Several papers in Japan have actually ... history and living in the Hachinohe area of Tohoku region in Aomori prefecture of Japan, in 1997, 2002 and 2007, respectively Hachinohe is situated in the northern part of Japan, with approximately ... years The risk of transmission through the contamination of T canis eggs in the field has clearly not been reduced in the area of the present study The importance of regular fecal examination in...

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Báo cáo lâm nghiệp: "Allozyme variation of Pinus pallasiana D. Don in Natural Crimean populations and in plantations in technogenously-polluted areas of the Ukraine steppes" ppsx

Ngày tải lên : 08/08/2014, 01:21

... The main locations of the larger provenances (Fig and Tab I) are: (a) the southern macro-slope of the main range of the Crimea mountains, natural stands coded C; (b) the Ukraine steppe near the ... services as provenances from Crimea and their main characteristics are summarised in Table I The Crimean black pine in polluted areas 391 Table I Mean traits of Pinus pallasiana examined populations ... Location of Black Pine natural stands and plantations examined (see also Tab I) system, namely the Crimean natural populations, with artificial stands growing in environments suffering from various...

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Báo cáo khoa học: "Relation between ecological conditions and fir decline in a sandstone region of the Vosges mountains (northeastern France) Anne-Laure Thomasa, Jean-Cl." potx

Ngày tải lên : 08/08/2014, 14:20

... commonly practised in permanent plots Stand age and altitude appeared as the two predominant “causal” variables when considering fir decline in the sandstone area, while the parent rock had no apparent ... provided a linear model expressing the intensity of damage (class or classes and 3) as a function of parameters related to vegetation, topography, lithology and climate The mathematical distance ... database of the sandstone part of the Vosges In order to circumvent the lack of soil data (only a map of soil types covering a part of study area was available), we built a second database of 178...

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Báo cáo khoa học: "Nutrient cycling in deciduous forest ecosystems of the Sierra de Gata mountains: aboveground litter production and potential nutrient return" pot

Ngày tải lên : 08/08/2014, 14:21

... with a density of 970 at the San Martin dc province of , -1 haamean trunk diameter of 10 cm and trunk height of 13 m (table I) The mean basal area is 28.6 m and the leaf area -1 trees a 2.2 Analytical ... leaves can be said to show the highest concentrations; N and Ca in the buds, Ca and Zn in the branches, K in the fruits, and above all Fe and Cu in the other plant remains are noteworthy A general ... VR and FG; and maritime Mediterranean at SM; [9]) rainy The soils are generally humic Cambisols (table I; [11]), developed over slate and graywackes at NF and VR, and over Caalkaline granite at...

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Báo cáo khoa học: "Nutrient cycling in deciduous forest ecosystems of the Sierra de Gata mountains: nutrient supplies to the soil through both litter and throughfall" ppt

Ngày tải lên : 08/08/2014, 14:21

... those of the rain water [36], indicating that the content of these elements in the rain water increases as the water passes through the forest canopy The elements showing the greatest increase in ... -1 The soils of these areas are generally humic Cambisols [11] developed on slates and graywackes at NF and VR and on Ca-alcaline granite at EP and FG [13] At SM, owing to the strong slope (approximately ... summers, falling under the classification of humid Mediterranean, with an average rainfall and temperature of approximately 580 mm yearand 10.4 °C for NF and -1 720 mm yeat and 12.9 °C for FG (table...

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Báo cáo khoa học: "Abietane and pimarane diterpene acid evolution in Scots pine Pinus sylvestris needles in relation to feeding of the pine sawfly, Diprion pini L." docx

Ngày tải lên : 09/08/2014, 03:24

... the pimarane and abietane diterpene acids We have shown that pimarane and abietane resin acids represent only a small part of the total acid fraction, mainly composed of labdanic acids and of hydroxylated ... compounds affecting sawfly larval development If abietane and pimarane diterpere acids interfere with larval mortality and feeding behaviour in D pini, the qualitative and quantitative evolutions of these ... resin acid standard solutions and corrected by reference to an internal standard of methylpalmitate The reported data are the averages of at least different determinations carried out on the same...

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Báo cáo y học: "Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort" ppt

Ngày tải lên : 09/08/2014, 13:22

... participated in the design of the study and also in collection of the data at the Hospital Universitario de la Princesa, was involved in the interpretation of data and drafted the manuscript All ... rheumatologists of the EMECAR group were involved in collection of data All of the authors read and approved the final version of the manuscript Additional file An image file containing a graph of ... LC participated in the design of the study and the interpretation of data, and helped to draft the manuscript MAD performed the statistical analysis and helped to draft the manuscript IG -A participated...

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Báo cáo y học: "Longitudinal evaluation the pulmonary function of the pre and postoperative periods in the coronary artery bypass graft surgery of patients treated with a physiotherapy protocol" ppt

Ngày tải lên : 10/08/2014, 09:21

... because of the cutting of the skin, muscles and pleura as well as the retraction of muscles and ligaments, pleural and septal nerve irritation from thoracic drains and occasional rib fractures ... writing and editing All of the authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests Received: February 2011 Accepted: 27 April ... writing and editing RRTC, MS, PPSS and SLDC participated in the study design, data analysis, manuscript writing and editing ACLN supervised the study and contributed to the data analysis, manuscript...

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báo cáo khoa học: " Government use licenses in Thailand: an assessment of the health and economic impacts" pptx

Ngày tải lên : 11/08/2014, 14:21

... including the NHSO, the MOPH’s NCI and Bureau of Policy and Strategy, and the Departments of Export Promotion and Foreign Trade in the Ministry of Commerce The availability of relevant data and the ... the authors have been involved in drafting and revising the manuscript and have read and approved the final manuscript 22 23 Competing interests The authors declare that they have no competing interests ... compared with nevirapine-based regimens in Thailand Journal of the Medical Association of Thailand 2008, 91:126-138 45 Karnon J, Bakhai A, Brennan A, Pandor A, Flather M, Warren E, Gray D, Akehurst...

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