... human and rat CB1 receptor The CB2 antibody was raised against a sequence between the N-terminal andthe first transmembrane domain ofthe protein ofthe human and rat CB2 receptor The specificity of ... almost all ofthe staining of these bands (Fig 3A) The most abundant band in human immature dendritic cells was the one at 83 kDa which may be related to a predominant glycosylation form ofthe CB1 ... dendritic cells band at 45 kDa andthe rat spleen at 47 kDa were less intense and are consistent with the previous glycosylated forms of human and rat CB2 receptors [47,48] The 39 kDa band was very...
... planetesimal theory Objections to the ChamberlinMoulton theory 126 The Jeans tidal theory 127 4.6.1 A description ofthe tidal theory 127 4.6.2 The tidal disruption of a star 129 4.6.3 The break-up of ... The spin axes ofthe Sun andthe planets 7.4.1 Spin axes andthe Solar Nebula Theory 7.4.2 Spin axes andthe Modern Laplacian Theory 7.4.3 Spin axes andthe Accretion Theory 7.4.4 Spin axes and ... Newton the basic structure ofthe solar systemandthe laws that govern the motions ofthe bodies within it have been well understood One central body, the Sun, containing most ofthe mass ofthe system...
... commercial banks andofthe value of focusing regulation on the nature ofthe activities being undertaken The Rules have clarified the prudential expectations ofthe BOG Better understanding ofthe requirements ... based on their repayment track record andthe quality ofthe systems used to manage them The promise of repeat loans andthe pressures of group or personal guarantees, and sometimes pledges of movable ... Post Office System It attained full bank status as National Savings and Credit Bank in 1972 under NRC Decree 38 The new management abandoned the use ofthe network ofthe Post Office System and...
... 90–15) and 255 (M+ – 131) The loss of mass 131 results from the scission ofthe C1–C2 and C4–C5 bonds Figure 4C illustrates mass spectra of isolated 7-DHP-MO-TMS, andthe synthesized standard The ... (Invitrogen), andthe isolation of RNA followed the manufacture’s protocol The synthesis of first-strand cDNA was performed using the Superscript preamplification system (Invitrogen) Either lg of total ... MHz) spectrum ofthe product of P450scc-mediated side-chain cleavage of 7-DHC (A) Spectrum ofthe enzymatic side-chain cleavage of 7-DHC; (B) spectrum of 7-DHP synthetic standard secondary antibody...
... planetesimal theory Objections to the ChamberlinMoulton theory 126 The Jeans tidal theory 127 4.6.1 A description ofthe tidal theory 127 4.6.2 The tidal disruption of a star 129 4.6.3 The break-up of ... The spin axes ofthe Sun andthe planets 7.4.1 Spin axes andthe Solar Nebula Theory 7.4.2 Spin axes andthe Modern Laplacian Theory 7.4.3 Spin axes andthe Accretion Theory 7.4.4 Spin axes and ... Newton the basic structure ofthe solar systemandthe laws that govern the motions ofthe bodies within it have been well understood One central body, the Sun, containing most ofthe mass ofthe system...
... uses The goal of this first validation study was to determine the initial measurement model and fundamental reliability and validity ofthe TRIM-Weight The cross sectional and web based nature of ... written to validate the psychometric properties of both the total as well as domain subscale scores andthe data from the validation study supports the claims for reliability and validity for ... interpretability ofthe solution A scree plot ofthe principle component solution was used as guidance to the number of components with eigenvalues of greater than one To confirm the factor structures and...
... and design ofthe original web-based survey FJS, SES and FP assessed the quality ofthe data collected and participated in the design ofthe validation study andthedevelopmentofthe statistical ... we report on thedevelopmentand validity ofthe ITAS Methods Developmentof ITAS The ITAS was developed to capture type diabetes patient's current appraisal of insulin therapy The instrument ... anticipated that the factors would be correlated The knick-criterion andthe Kaiser-criterion (Eigenvalue > 1) were used to determine the optimal number of factors [17] Next, the scree plot ofthe Eigenvalues...
... participated; the participant was required to be the primary caregiver ofthe child, and had to be willing to participate throughout the course ofthe study and to complete the questionnaires at Weeks and ... female, usually mothers, with a mean age of 37.1 years (Table 1) The majority ofthe subjects were white Because only one ofthe adults taking part in the study was not the parent ofthe participating ... coordination ofthe study and helped to draft the manuscript RD participated in the design and coordination ofthe study XL contributed statistical analysis and helped to draft the manuscript RA and LA...
... Organization Quality of Life Group [16,17] for thedevelopmentand adaptation of quality of life measures and was used for thedevelopmentofthe WHOQOL-OLD module [18,19] Regarding developmentof new measures ... illustrate the potential combination of classical psychometric theory and Rasch Analysis in the validation ofthe AAQ instrument in a Brazilian sample of older adults Methods Pilot study The pilot ... item and subscale correlations and internal reliability No missing values were found in any ofthe 44 items in the Brazilian sample The analysis ofthe pooled international data indicated the...
... in the decisions throughout the process ofdevelopmentand finalisation ofthe questionnaire They gave their approval at each ofthe milestones ofthedevelopmentand finalisation process The ... modules andthe lack of data from PCA and Multi-trait analyses on the questionnaire as a whole could be raised as limitations, as the purpose of these analyses is to allow the definition ofthe structure ... between some ofthe IDEEL dimensions andthe SF-36 (such as “impact on work” of IDEEL and “role physical” of SF-36; “emotional impact” of IDEEL andthe mental component (or some ofthe related...
... and design ofthe original web-based survey FJS, SES and FP assessed the quality ofthe data collected and participated in the design ofthe validation study andthedevelopmentofthe statistical ... we report on thedevelopmentand validity ofthe ITAS Methods Developmentof ITAS The ITAS was developed to capture type diabetes patient's current appraisal of insulin therapy The instrument ... anticipated that the factors would be correlated The knick-criterion andthe Kaiser-criterion (Eigenvalue > 1) were used to determine the optimal number of factors [17] Next, the scree plot ofthe Eigenvalues...
... participated; the participant was required to be the primary caregiver ofthe child, and had to be willing to participate throughout the course ofthe study and to complete the questionnaires at Weeks and ... female, usually mothers, with a mean age of 37.1 years (Table 1) The majority ofthe subjects were white Because only one ofthe adults taking part in the study was not the parent ofthe participating ... coordination ofthe study and helped to draft the manuscript RD participated in the design and coordination ofthe study XL contributed statistical analysis and helped to draft the manuscript RA and LA...
... Organization Quality of Life Group [16,17] for thedevelopmentand adaptation of quality of life measures and was used for thedevelopmentofthe WHOQOL-OLD module [18,19] Regarding developmentof new measures ... illustrate the potential combination of classical psychometric theory and Rasch Analysis in the validation ofthe AAQ instrument in a Brazilian sample of older adults Methods Pilot study The pilot ... item and subscale correlations and internal reliability No missing values were found in any ofthe 44 items in the Brazilian sample The analysis ofthe pooled international data indicated the...
... selfcompleted during the study: The symptom items ofthe B&B Scale were assessed during screening, at study visit (baseline), and at the end ofthe study The B&B Scale assesses the severity ofthe signs ... reliability, and construct and discriminant validity; and to evaluate the ease of use ofthe electronic EPBD (administered on a data capture device based on the Palm Pilot platform called the LogPad® System ... Clinical data included date and method of endometriosis diagnosis; date of any surgical treatments for endometri- osis; date of last menstrual period and information on the regularity of menstrual...
... to thedevelopmentof damaging immune reactions in autoimmunity and allergy The identification of precise genetic variants controlling both parasite susceptibility and immunopathology offers the ... deeper understanding ofthe intimate co-evolution of pathogens andthe immune system 10 11 12 13 14 Acknowledgements The author’s research is supported by grants from the Wellcome Trust, the Medical ... well recognized for the regulation of immune responses The effect of parasites, for example, has been to dampen, rather than fully ablate, immune responsiveness, andthe degree of immunosuppression...
... score of 10, and so the highest possible score is 100 (the higher the score, the greater the impact ofthe syndrome on the person) The Italian version ofthe FIQ has been previously validated ... participated in the analysis and interpretation ofthe data SG contributed to the acquisition ofthe data FA contributed to the interpretation ofthe data and critically reviewed the manuscript WG provided ... them from completing the questionnaire The study was approved by the Ethics Committees ofthe Polytechnic University ofthe Marche Medical School, andthe Sacco University Hospital, and all of...
... from the Head ofthe Department of Health in the Free State, andthe study protocol was approved by the Human Research Ethics Committees ofthe Faculty of Health Sciences ofthe University ofthe ... their time and cooperation The financial support ofthe STRETCH trial by the IDRC, Irish AID andthe UK Medical Research Council, andof doctoral studies (KU) from the National Research Foundation, ... summarises the characteristics ofthe ART training available to nurses in all clinics across the province andthe training offered as part ofthe intervention The details of these training programmes...
... understanding ofthe anatomy and function ofthe ear andthe auditory nervous system, and it discusses the cause and treatment of hearing disorders Most books on hearing focus either on the anatomy ... comprehensive coverage of disorders ofthe auditory system emphasizing the interaction between pathologies ofthe middle ear andthe cochlea andthe function ofthe nervous systemand vice versa Hyperactive ... function ofthe cochlea than of any other sensory organ C H A P T E R Anatomy ofthe Ear ABSTRACT 10 The ear consists ofthe outer ear, the middle ear andthe inner ear The outer ear consists of the...
... at the entrance ofthe ear canal compared with the sound pressure that is measured in the place ofthe head The effect ofthe head on the sound at the entrance ofthe ear canal is related to the ... vibration ofthe malleus, thus a measure ofthe function ofthe tympanic membrane (The velocity ofthe vibration is the first derivative ofthe amplitude andthe velocity for sinusoidal vibrations ... ratio between the effective area ofthe tympanic membrane andthe area ofthe stapes footplate, but the lever ratio ofthe middle ear bones also contributes The ratio of areas ofthe BOX 2.2 SOUND...
... close to the surface ofthe floor ofthe fourth ventricle (Fig 5.15B) [72] The other part ofthe olivocochlear system projects mainly to the contralateral cochlea andthe fibers of that system ... near the frequency of a formant will show a periodic pattern with the frequency ofthe formant The spectra of these histograms show harmonics ofthe fundamental frequency ofthe vowel andthe ... drawing ofthe connections between the classical andthe non-classical routes andthe lateral nucleus ofthe amygdala (AL), showing the “high route” andthe “low route” Connections between the basolateral...