determinants of decline in lung function
báo cáo hóa học: " A prospective study of decline in lung function in relation to welding emissions" pdf
Ngày tải lên :
20/06/2014, 00:20
... (640 ml in FEV1), suggesting an independent effect of welding fume on the lungs [19] Few longitudinal studies in welders addressing decline in lung function have been published (18–20) In a two-year ... welding technology We also examined decline in lung function according to exposure estimates assuming a continuous fall of exposure levels from 1989 onwards but found no indications of effects of ... baseline was 17–30 years The overall annual decline in FEV1 was 11.1 ml Continuing smoking was associated with increased loss in FEV1 and atopy in smokers further increased the loss in FEV1 Continued...
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Báo cáo y học: "Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study" ppsx
Ngày tải lên :
12/08/2014, 18:21
... coefficients for decline in FEV1 per pack-year in women compared to men and Connett et al reported similar rates of decline in men and women but a swifter regain in FEV1 in women who quit smoking [4,7] ... quantitative information on cigarettes smoked during two time periods, we show similarities and differences in the effect of smoking on lung function decline between men and women Decline due to smoking ... baseline, change in weight, change in BMI between surveys and years since quitting Predictors in each model are shown in the footnote to table Baseline lung function parameters were included in all models...
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Báo cáo y học: "Determinants of improvement in quality of life of alcohol-dependent patients during an inpatient withdrawal programme"
Ngày tải lên :
03/11/2012, 10:52
... QoL of patients during care and the influence of QoL on the prognosis of alcoholism are unknown (22, 23) The aims of this study in a clinical setting was: 1) to determine the change in QoL of ... Summary of >6 points in two-thirds of patients and an increase in Mental Component Summary score of >8 points in two-thirds of patients The variables associated with a large increase (>6) in Physical ... number of days of abstinence during the months preceding hospitalisation, duration of alcohol dependence, length of time since the first alcohol-related period of care, family history of alcoholism...
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NOTES ON THE ROLE OF EDUCATION IN PRODUCTION FUNCTIONS AND GROWTH ACCOUNTING pot
Ngày tải lên :
06/03/2014, 21:20
... an increase in the number of plumbers results in a larger increase in total "real" labor input than a similar increase in the number of clergymen We can illustrate the construction of such indexes ... education of the total labor force in a state for the measurement of the quality of the labor force of individual industries within the same state But the difficulty of estimating interaction terms of ... measured in man- hours The rate of growth of the index of total labor input, say L, is: i — —— L — where v1 is the relative share of the lth category of labor in the total value of labor input.3...
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Reproductive Senescence in a Long-Lived Seabird: Rates of Decline in Late-Life Performance Are Associated with Varying Costs of Early Reproduction pot
Ngày tải lên :
28/03/2014, 16:20
... productivity declined sharply E94 The American Naturalist Statistical Analyses Testing for Within-Individual Declines in Performance and Factors Associated with These Declines Within-individual declines ... treated as a continuous variable in the model because we were interested in how breeding success declines linearly in the years leading up to the death of individuals and how this decline (slope) ... birds breeding later, we repeated the GLMM with relative laying date of individuals each year included as a continuous fixed effect Testing for Declines in Probability of Breeding or Holding a Site...
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Báo cáo khoa học: Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73c in lung cancer doc
Ngày tải lên :
29/03/2014, 09:20
... to )204 bp upstream of the TSS of the human p73 P1 promoter containing conserved, functional Sp1-binding sites Reduction of the endogenous Sp1 levels or inhibition of Sp1 binding to this region ... treatment of A549 cells with increasing concentrations of the Sp1 inhibitor mithramycin A (Fig 3B), which not only interferes with the transcription of genes containing GC-rich regions in their ... combinations between differential N-terminal domain and C-terminal domain [15] Despite the rarity of p73 mutations, overexpression of p73 isoforms is common in several types of cancer [14,16], including...
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Báo cáo sinh học: "Elevated expression of CDK4 in lung cancer" pptx
Ngày tải lên :
18/06/2014, 19:20
... staining intensity and the percentage of positive staining areas of cells The staining intensity was scored as previously described(0-3) [8,9] and the percentage of positive staining areas of ... localization of CDK4 protein in 89 archived paraffin-embedded lung cancer samples and 23 normal lung tissues using immunohistochemical staining (Figure 1A-E) Specific CDK4 protein staining was found in ... factor in promoting the initiation and development of tumors In order to clarify the role of CDK4 in the pathogenesis of lung cancer, we explored the correlation of its protein expression with clinicopathologic...
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báo cáo hóa học:" Elevated expression of CDK4 in lung cancer" ppt
Ngày tải lên :
20/06/2014, 03:20
... staining intensity and the percentage of positive staining areas of cells The staining intensity was scored as previously described(0-3) [8,9] and the percentage of positive staining areas of ... localization of CDK4 protein in 89 archived paraffin-embedded lung cancer samples and 23 normal lung tissues using immunohistochemical staining (Figure 1A-E) Specific CDK4 protein staining was found in ... factor in promoting the initiation and development of tumors In order to clarify the role of CDK4 in the pathogenesis of lung cancer, we explored the correlation of its protein expression with clinicopathologic...
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Health and Quality of Life Outcomes BioMed Central Research Open Access Quality of life in lung potx
Ngày tải lên :
20/06/2014, 15:20
... Baseline Follow-up Affluent/intermediate (n = 35) Mean (SE) Role functioning Physical functioning Cognitive functioning Social functioning Emotional functioning Global quality of life Deprived (n = ... study findings are explained elsewhere [9] Here the focus is on quality of life and patients' socioeconomic status In summary, patients' quality of life was assessed in two points in time: baseline ... follow-up functioning and global quality of life scores on the EORTC QLQ-C30 (the higher values indicate a higher level of functioning and quality of life, min.: 0, max.: 100) Baseline Follow-up...
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Báo cáo y học: "The determinants of change in tibial plateau bone area in osteoarthritic knees: a cohort study" doc
Ngày tải lên :
09/08/2014, 06:22
... osteophytes; grade of JSN=percentage change per increase in grade of jointspace narrowing; baseline tibial area = percentage change per mm2 increase in baseline tibial plateau bone area bIncludes age, ... area, and grade of medial joint-space narrowing explained 4.6% of variance in annual percentage change in medial tibial bone area BMI and grade of medial joint-space narrowing were independently ... by joint-space narrowing [35] However, we did not take serum levels or intake of vitamin D into account in this study Competing interests The author(s) declare that they have no competing interests...
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Báo cáo y học: "Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study pptx
Ngày tải lên :
10/08/2014, 05:21
... by smoking status Pack-year of smoking was calculated by multiplying the number of packs of cigarette smoked per day and the number of years of smoking 2Abnormal lung function was defined as ... whether cigarette smoking affects lung function in a similar way in HIV-positive population Hence, the literature is unclear on the effects of smoking on lung function in HIV-positive subjects, ... loss of lung function as their HIVnegative counterparts [13,14], which did not support the hypothesis that lung function decline is greater in the HIV-positive population We should keep in mind...
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báo cáo khoa học: " Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells" ppsx
Ngày tải lên :
10/08/2014, 10:21
... rapamycin will result in some beneficial modulation of the cancer killing properties of docetaxel in lung cancer cells [20,21] To the best of our knowledge, the effect of including rapamycin in combination ... twice with cold PBS, resuspended in 250 μl of binding buffer, and stained with staining solution containing Annexin V/FITC and PI After incubation in the dark for 30 min, cells were analyzed by FACSCalibur ... effectors of rapamycin and docetaxel-induced signaling pathways in lung cancer cell lines As a first step, we examined the expression and phosphorylation levels of some proteins known to be involved in...
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Báo cáo y học: " A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease" pot
Ngày tải lên :
12/08/2014, 15:20
... reduced fat free mass and declined further over the course of a year The only parameter predicting decline in QMVC during follow up was QMVC at baseline Of note the mean decline in QMVC was 4.3% which ... of the hospital Thirteen (11.9%) declined to come back for further testing Of these, two felt too unwell to come, two declined to travel and nine gave no specific reason For 16 of the remaining ... to determine their utility in predicting decline in fat free mass and quadriceps strength The factors to be evaluated were indices of lung function, oral corticosteroid exposure and having frequent...
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Báo cáo y học: " Role of TNF-α in lung tight junction alteration in mouse model of acute lung inflammation" doc
Ngày tải lên :
12/08/2014, 15:21
... proteins involved in TJ formation include occludin and members of a large class of proteins called claudins [39] These proteins contain four transmembrane domains and are thought to be the points ... proteins, including ZO1, junction adhesion molecule 1, occludin, claudin-1, and claudin-4 [27] The effects of pro-inflammatory cytokines on lung epithelial barrier function were studied using lung ... as in mice with a targeted deletion of the TNF-αR1 gene As a result of these efforts, we point out that acute lung inflammation induced alterations in the function of lungs, is due, at least in...
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Báo cáo y học: "Inhaled steroid/long-acting β2 agonist combination products provide 24 hours improvement in lung function in adult asthmatic patients" pps
Ngày tải lên :
12/08/2014, 16:20
... prebronchodilator FEV1 of >50% predicted normal and demonstrate an increase from baseline in FEV1 of at least 15% of the predicted value 15 minutes after administration of 400 mcg of salbutamol Subjects ... adverse events The baseline characteristics of subjects in both studies, including dose of inhaled corticosteroid are shown in Table Primary endpoints Study A Both SFC and FBC increased FEV1 at 16 ... change from baseline in morning PEF was 25 L/min in both the SFC and FBC groups In addition, the median number of days with no use of relief medication was 63% in the SFC group and 61% in the FBC group...
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Báo cáo khoa học: " A Systematic review of determinants of mortality in high frequency oscillatory ventilation in acute respiratory distress syndrome" potx
Ngày tải lên :
12/08/2014, 23:21
... transformation of incidence of death was calculated by taking the natural logarithm of incidence of death divided by incidence of survival The weight of an individual study was determined by the inverse of ... unidentified intermediate determinants of lung damage remained Moreover, the association of prolonged time on CV before initiating HFOV treatment and increased risk of death disappeared by adjusting for ... incidence at 30 days in survivors, incidence of still being ventilated at 30 days, and incidence of survival without being ventilated at 30 days Baseline characteristics of these cohorts that...
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Báo cáo khoa học: "Causes of death and determinants of outcome in critically ill patient" pot
Ngày tải lên :
13/08/2014, 03:20
... Renal Creatinine ≤ 2.0 mg/dl Creatinine >2.0 mg/dl; doubling of creatinine in patients with previous compensated renal failure Continuous veno-venous haemofiltration Hepatic Bilirubin 50% of normal need and/or dopamine >5 μg/kg per minute, dobutamine 10 μg/kg per minute, AVP, epinephrine, norepinephrine, ... AVP, epinephrine, norepinephrine, combination of catecholamines, IABP, VAD Gastrointestinal Normal gastrointestinal function, no bleeding Ileus >7 days or bleeding requiring ≤ six blood products...
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Báo cáo y học: "Clinical expert guidelines for the management of cough in lung cancer: report of a UK task group on cough" potx
Ngày tải lên :
13/08/2014, 10:20
... Neltenexine-2 trials Sinecod linctus (butamirate) with a similar effect to that of small dose of Codeine-1 trial Overview of findings Asthma (cough often secondary from systematic outcome) review in ... feeling comfortable having these guidelines applied in their hospital (= 4) The likelihood of using these guidelines in the reviewers’ own practice was explored with a singleitem scale ranging ... Overview of findings Lung cancer patients, N = trials from Cochrane systematic review in cancer [12]** Brachytherapy in addition to EBRT resulted in higher improvements in cough at doses of 15 Gy in...
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Báo cáo y học: "Determinants of mortality in non-neutropenic ICU patients with candidaemia" pps
Ngày tải lên :
13/08/2014, 18:22
... Antifungal therapy was initiated in 156 (85%) patients: of these, fluconazole in 76%, amphotericin B deoxycholate in 12%, a lipid formulation of amphotericin B in 4%, caspofungin in 4%, and voriconazole ... Ethics Committees of all participating institutions Informed written consent was obtained from patients that were included in the study Definitions The definition of ICU acquisition of candidaemia ... diagnosis of candidaemia (84%) and at day (76%) The source of candidaemia was attributed to an intravascular device in 35%, an intra-abdominal source in 10%, the urinary tract in 3%, other sources in...
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Báo cáo y học: "Role of CD14 in lung inflammation and infection" pptx
Ngày tải lên :
13/08/2014, 20:21
... binding of rough LPS and binding of SP-C to CD14 augmented binding of smooth LPS [15], whereas binding of SP-A to CD14 reduced binding of smooth LPS and binding of SP-D to CD14 decreased binding ... reorganization of its cytoplasmic domain, enabling the recruitment of the adaptor proteins, myeloid differentiation primary-response protein 88 (MyD88) and TIR-domain-containing-adaptorprotein-inducing-interferon ... trigger cell activation Binding of LPS to CD14 is regulated by additional accessory receptors in the lung, including LPS-binding protein (LBP) and a number of surfactant proteins (SP) Furthermore,...
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