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derived target based and cytotoxic therapies for breast cancer and other malignancies

Báo cáo khoa học:

Báo cáo khoa học: "Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer" pot

Báo cáo khoa học

... 33(4):445-8 Early Breast Cancer Trialists’ Collaborative Group: Tamoxifen for early breast cancer: an overview of the randomized trials Lancet 1998, 351:1451-1467 Cuzick J, Powles T, Veronesi U, Forbes ... for Research on Cancer, Lyon, France 1996, 66:253-365 11 Swerdlow AJ, Jones ME: Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study J Natl Cancer Inst 2005, ... toxicity and feasibility of tamoxifen for prevention of breast cancer Br J Cancer 1989, 60(1):126-31 Fisher B, Costantino JP, Redmond CK, Fisher ER, Wickerham DL, Cronin WM: Endometrial cancer...
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Báo cáo khoa học:

Báo cáo khoa học: " Hypofractionated radiotherapy after conservative surgery for breast cancer: analysis of acute and late toxicity" ppt

Báo cáo khoa học

... Darby S, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG): Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year ... START Trialists’ Group: The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial Lancet 2008, 9:331-41 ... START Trialists’ Group: The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial Lancet 2008, 371:1098-17...
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Báo cáo khoa học:

Báo cáo khoa học: "Target splitting in radiation therapy for lung cancer: further developments and exemplary treatment plans" pps

Báo cáo khoa học

... withdrawn and the primary tumor alone is treated to 79,2 Gy V20 right and left lung and V25 both lungs is 49%, 22% and 26%, respectively V50 for the heart is 2% Peripheral tumor located lateral and ... proposed this method for head and neck, breast and craniospinal treatments With the availability of independently moving jaws asymmetric collimators were used to split the beam for head and neck patients ... tinely for lung cancer patients in all stages During the past years, this technique has continuously been evolved with regard to optimizing the procedures for quality assurance and raising conformity...
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báo cáo khoa học:

báo cáo khoa học: "Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy" docx

Báo cáo khoa học

... greater cytotoxicity after longer treatments (72 hours) Furthermore, it was also demonstrated that its cytotoxic effect differed between breast normal (MCF-10A) and breast carcinoma (4T1 and MCF-7) ... investigator and takes primary responsibility for the paper MLBC, ZGML, ARS* and SNB participated in the design of the study and SNB co-ordinated the research; MLBC, ESN, RCAP, RGSO and LHML performed ... of a- and b-carboxyl carbon atoms in the complex (195.3 and 192.8 ppm, respectively) appear shifted in comparison with those with free ligands (179 and 176.5 ppm, respectively) The shift and split...
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Tài liệu Screening for Breast Cancer: Systematic Evidence Review Update for the U. S. Preventive Services Task Force doc

Tài liệu Screening for Breast Cancer: Systematic Evidence Review Update for the U. S. Preventive Services Task Force doc

Sức khỏe giới tính

... BRCA1 and BRCA2 increase individual risks for breast cancer 60-85% and may be identified in 5-10% of all breast cancer cases.28 Personal history of noninvasive breast cancer or previous abnormal breast ... Tripathy D Targeted therapies in breast cancer Breast 2005;11(Suppl 1):S30-S35 Smith RA, Saslow D, Sawyer KA, et al American Cancer Society guidelines for breast cancer screening: Update 2003 CA: Cancer ... interventions, outcomes, and harms of the screening process (Figure 1) The target population includes women without preexisting breast cancer and not considered at high risk for breast cancer based on extensive...
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Tài liệu SCREENING FOR BREAST CANCER WITH MAMMOGRAPHY ppt

Tài liệu SCREENING FOR BREAST CANCER WITH MAMMOGRAPHY ppt

Sức khỏe giới tính

... you would like further information: • the National Breast Cancer Coalition (www.stopbreastcancer.org), whose members are mainly women with breast cancer, and • the Center for Medical Consumers (www.medicalconsumers.org) ... cell changes and cancers, all of them are treated Therefore, screening results in treatment of many women for a cancer disease they not have, and that they will not get Based on the randomised trials, ... disease and cancer It therefore no longer seems reasonable to attend for breast cancer screening In fact, by avoiding going to screening, a woman will lower her risk of getting a breast cancer...
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Báo cáo sinh học:

Báo cáo sinh học: " Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy" pptx

Điện - Điện tử

... docetaxel-loaded nanoparticles based on poly(lactideco-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies ... characterized for particle size, zeta potential, EE%, drug release kinetics, morphology, crystallinity, and cytotoxicity on the SUM 225 breast cancer cell line by dynamic light scattering, high performance ... precursor compound, and then isolated [2] Doc is a highly potent, cytotoxic, and antimitotic agent used in the treatment of various types of cancers, including metastatic breast, ovarian, prostate,...
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Báo cáo hóa học:

Báo cáo hóa học: " A Novel Docetaxel-Loaded Poly (e-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment" pot

Hóa học - Dầu khí

... 10.380, 8.726, and 5.945 lg/mL for TaxotereÒ to 7.388, 3.643, and 1.244 lg/mL for PCL NP formulation and to 1.019, 0.384, and 0.196 lg/mL for PCL/Pluronic F68 NP formulation after 24, 48, and 72 h ... 49.16% (i.e a 11.42% increase in cytotoxicity, p [ 0.05) for PCL NP formulation and 36.63% (i.e a 38.88% increase in cytotoxicity, p \ 0.05) for PCL/Pluronic F68 NP formulation Similarly, it can ... release was only 13.57, 20.61, and 27.94% for PCL nanoparticles and 22.40, 31.09, and 37.44% for PCL/Pluronic F68 nanoparticles after 1, 2, and days, respectively, and the release started from...
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Báo cáo sinh học:

Báo cáo sinh học: "Reasons for breast cancer heterogeneity" pptx

Báo cáo khoa học

... enough for therapeutic selection but knowledge of both genotype and phenotype is required Furthermore, Chin et al [1] provide lists of copy number alterations and potential cancer genes in breast cancers ... including self-renewal and tumorigenicity in breast cancer cells [14] and also invasion and metastasis [15,16] They are thought to be important in oncogenesis (see [17,18] for reviews) Journal ... subtypes [2] and of variations in genome instability and heterogeneity of estrogen receptor (ER)-negative tumors [1] (arrows) contribute to the understanding and classification of breast cancers Blenkiron...
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báo cáo khoa học:

báo cáo khoa học: "Axillary lymph node dissection for breast cancer utilizing Harmonic Focus®" pps

Báo cáo khoa học

... BK: Seroma formation following breast cancer surgery Breast J 2003, 5:385-8 Woodworth PA, McBoyle MF, Helmer SD, Beamer RL: Seroma formation after breast cancer surgery: incidence and predicting ... following breast cancer surgeries: seromas following breast cancer surgeries Breast J 2007, 13:588-92 Burak WE Jr, Goodman PS, Young DC, Farrar WB: Seroma formation following axillary dissection for breast ... since October 2007 and is designed for open procedures It has been used for dissection in surgery of the liver, gallbladder, thyroid and breast [13-18] It has been used in other lymphatic dissections...
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báo cáo khoa học:

báo cáo khoa học: "Clinical relevance of "withdrawal therapy" as a form of hormonal manipulation for breast cancer" doc

Báo cáo khoa học

... of JFR and KLC AA collected data, performed analysis, drafted, revised and finalised the manuscript KLC and JFR revised and approved of the contents of the manuscript All authors read and approved ... Dodwell DJ, Anderson H, Redford J: Response after withdrawal of tamoxifen and progestogens in advanced breast cancer Annals Of Oncology: Official Journal Of The European Society For Medical Oncology/ ... Schiff R: Crosstalk between Estrogen Receptor and Growth Factor Receptor Pathways as a Cause for Endocrine Therapy Resistance in Breast Cancer Clinical Cancer Research 2005, 112:865s-870s Legault-Poisson...
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Báo cáo khoa học:

Báo cáo khoa học: "Predictive factors for breast cancer in patients diagnosed atypical ductal hyperplasia at core needle biopsy" doc

Báo cáo khoa học

... of the female breast A long-term follow-up study Cancer 1985, 55:2698-2708 Dupont WD, Page DL: Risk factors for breast cancer in women with proliferative breast disease New England Journal of ... sequence alignment and drafted and described the manuscript AL carried out the Pathologic diagnosis BJS and SSJ conceived of the study, and participated in its design and coordination and helped to ... American College of Radiology Breast Imaging Reporting and Data System lexicon and the final assessment categories All lesions were evaluated for size on imaging and presence of microcalcification...
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Báo cáo khoa học:

Báo cáo khoa học: " Dose-response relationship for breast cancer induction at radiotherapy dose" doc

Báo cáo khoa học

... relationship for breast cancer was derived based on the analysis of breast cancer induction after Hodgkin’s disease, a cancer risk model developed for high doses including fractionation based on ... of model parameters for a dose-response relationship for breast cancer covering dose levels relevant for radiotherapy In addition a model for the age dependence of breast cancer risk was verified ... were treated for Hodgkin’s disease between 1965 and 1994 The mean and median age at diagnosis was 22 years Point dose reconstruction for the breast cancer was possible for 102 cases and 257 controls...
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báo cáo khoa học:

báo cáo khoa học: "Novel therapies in breast cancer: what is new from ASCO 2008" ppsx

Báo cáo khoa học

... these novel therapies to current treatment standards and to continue to search for newer agents that are under investigation for use in breast cancer The role of most of these biologic and targeted ... currently approved for the treatment of both colorectal cancer and head and neck cancer Its use in breast cancer has been evaluated in a phase II study of weekly irinotecan and carboplatinum with ... necessary for cancer growth, invasion and metastasis Several therapeutic agents have been developed which target this pathway and have already been incorporated into standard treatment regimens for...
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báo cáo khoa học:

báo cáo khoa học: " Implementing academic detailing for breast cancer screening in underserved communities" pps

Báo cáo khoa học

... to patients Patient-held mini-records of preventive services Performance targets for mammographyc Performance targets for clinical breast exams 33 14 20 26 10 52 44 34 17 0.6 16 10 0.01 0.05 0.02 ... routine use of performance targets for mammography, compared to 8% of the control physicians (p = 0.009) Fifty percent of the physicians had performance targets for clinical breast examinations; ... Oncology, March, 2002 References American Cancer Society: Breast Cancer Facts and Figures 2005–2006 Atlanta: American Cancer Society, Inc Centers for Disease Control and Prevention, 2003 National Health...
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báo cáo khoa học:

báo cáo khoa học: " Implementing academic detailing for breast cancer screening in underserved communities" pptx

Báo cáo khoa học

... to patients Patient-held mini-records of preventive services Performance targets for mammographyc Performance targets for clinical breast exams 33 14 20 26 10 52 44 34 17 0.6 16 10 0.01 0.05 0.02 ... routine use of performance targets for mammography, compared to 8% of the control physicians (p = 0.009) Fifty percent of the physicians had performance targets for clinical breast examinations; ... Oncology, March, 2002 References American Cancer Society: Breast Cancer Facts and Figures 2005–2006 Atlanta: American Cancer Society, Inc Centers for Disease Control and Prevention, 2003 National Health...
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Báo cáo y học:

Báo cáo y học: "Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues" pptx

Báo cáo khoa học

... REPORT Open Access Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues Lachlan ... function, by characterizing, for the first time, the structure-function relationships of a larger panel of Envs derived from brain and other tissues (n = 81) Production and characterization of a ... established and characterized a new panel of Envs (n = 81) derived from autopsy brain and other tissues of subjects who died from AIDS Production of three-dimensional gp120 models and characterization...
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Tumour conditioned macrophages up regulate endothelial derived fibronectin to facilitate lung metastasis in breast cancer

Tumour conditioned macrophages up regulate endothelial derived fibronectin to facilitate lung metastasis in breast cancer

Kỹ thuật - Công nghệ

... JNK/cJUN signalling and its role in cancer 37 1.5.2 STAT3 signalling and its role in cancer 39 1.6 Breast cancer 42 1.6.1 Tumour microenvironment and breast cancer progression ... thank you for being so understanding, supportive and caring during the last year of my study Thanks for sharing my joy, sorrow and hardship Thank you for being there and looking out for me all ... 77,78, pancreatic cancer 79; and with bone metastasis in breast 80,81 and prostate cancers 82 Similarly, α6β4 expression in breast cancer could be correlated to increase in tumour size and reduced...
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