công ty cổ phần tư vấn đầu tư và xây dựng giao thông vận tải chi nhánh thành phố hồ chí minh
Báo cáo y học: "Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study" pdf
... Specificity = 23% Sensitivity = 90% Predictive value NPV = 68% PPV = 55% Threshold = -0.35 Biomarker modela (n = 308) True/Predicted NR R Accuracy NR R 62 16 88 142 Specificity = 41% Sensitivity = ... Specificity = 48% Sensitivity = 80% R 17 67 Predictive Value NPV = 86% PPV = 36% Threshold = -1.3 Biomarker modela (n = 308) True/Predicted NR R Accuracy NR 137 87 Specificity = 61% Sensitivity = ... even these markers were unable to achieve high enough specificity and sensitivity to be routinely useful predictors Thus, additional testing of serum and other types of markers from other studies...
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Báo cáo y học: "Potential bias in testing for hyperprolactinemia and pituitary tumors in risperidone-treated patients: a claims-based study" pps
... B, Joriassen RC: Prevalence of hyperprolactinemia in schizophrenia: association with typical and atypical antipsychotic treatment J Clin Psychiatry 2004, 65:1491-1498 Kapur S, Langlois X, Vinken ... http://www.annals-general-psychiatry.com/content/8/1/5 antipsychotics Patients treated with typical antipsychotics were generally older than those treated with atypical agents, with ziprasidone-treated ... Ziprasidone Haloperidol Perphenazine Other typicals (page number not for citation purposes) http://www.annals-general-psychiatry.com/content/8/1/5 Annals of General Psychiatry 2009, 8:5 Table 1: Patient...
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Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot
... Stohl W, Metyas S, Tan SM, Cheema GS, Oamar B, Roschke V, Wu Y, Baker KP, Hilbert DM: Inverse association between circulating APRIL levels and serological and clinical disease activity in patients ... repopulation occurred All patients showed a clinical response measured as SLAM (systemic lupus activity measure) score (Table and [18]) or in histopathological analysis of kidney biopsies (I Gunnarsson, ... presented in Table All patients were recruited from the Rheumatology Clinic at the Karolinska University Hospital, Stockholm, Sweden Thirteen non-treated healthy subjects, median age 60 years (range...
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Báo cáo y học: " Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients" potx
... Safeguarding of CD4+ lymphocytes viability Figure Safeguarding of CD4+ lymphocytes viability Representative flow cytometry histograms (patient no 9) characterizing viability of CD4+ T cell subset at the ... death CD4+ T cells viability was analyzed by flow cytometry after two days of preincubation and five days of culture For patients nos 8, 9, 15, and 23, cell viability analysis using the 7AAD ... reservoir and its capacity to induce a rescuable virus production in untreated and HAART-treated patients Our approach permitted to enumerate HIV-1-SCs and to assess the functionality of unintegrated...
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Báo cáo hóa học: " Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab" doc
... of the twenty-one non-responders had an increased EGFR-GCN (p < 0.0001) However, there is no consensus on the predictive role of increased EGFR-GCN due to difficulty in reproducibility of the ... weeks Toxicity was graded according to the National Cancer Institute Common Toxicity Criteria (version 2.0) Pretreatment and Follow-Up Studies History, physical examinations, and a safety assessment ... via E Chianesi 53, 00144 Rome, Italy, 3Department of Clinical Pathology, Regina Elena Institute, via E Chianesi 53, 00144 Rome, Italy, 4Department of Statistics, Regina Elena Institute via E Chianesi...
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Báo cáo y học: "Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turk
... 114.7 (46.4) 5 2 Abbreviations: CABG, coronary artery bypass graft; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MI, myocardial infarction; SAP, stable angina pectoris; USAP, unstable ... angiographic rather than clinical end points, clinical trials comparing the safety and efficacy between these DES types and BMSs have yielded inconsistent results In the ENDEAVOR I, II,II Continued ... and PES in unselected patients treated in daily practice remains controversial The long-term safety of DESs remains in question (10-11) Despite the results of meta-analyses of randomized studies...
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Tài liệu Differences in 4-Year Health Outcomes for Elderly and Poor, Chronically III Patients Treated in HMO and Fee-for-Service Systems ppt
... switching within elderly and poverty subgroups along with average outcomes for those who did and did not switch As documented elsewhere (MOS unpublished data), the relative probability of switching ... majority (54%) were female About 22% were at or below 200% of the poverty line; 16% of those reported being covered by Medicaid Three of 10 eligible for Medicare were also in the poverty group ... scores estimated using the internal-consistency reliability method The construction of summary measures, score reliability and validity, and normative and other interpretation guidelines are...
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Predictors of relapse among pulmonary tuberculosis patients treated in a DOTS programme in South India pot
... No Yes Drug regularity Regular Irregular Drug sensitivity profile—0 months Sensitive Resistant to H and/or HR Smear conversion at months Yes No Initial smear grading Scanty, 1ϩ 2ϩ, 3ϩ Initial ... and sensitivity testing London, UK: Butterworth, 1968 Canetti G, Fox W, Khomenko A, et al Advances in techniques of testing mycobacterial drug sensitivity, and the use of sensitivity tests in ... smear results), the relapse rate was 10% Drug susceptibility pattern at the time of relapse Of the 487 patients for whom drug susceptibility results were available at the start of treatment, 455...
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Báo cáo hóa học: " Updated survivals and prognostic factor analysis in myeloma treated by a staged approach use of bortezomib/thalidomide/dexamethasone in transplant eligible patients" pot
... Therefore, patients who failed to achieve >75% paraprotein reduction, and hence ultimately require VTD salvage, could in fact be predicted by the ability to achievev a PR after one cycle of VAD, ... account for the differential VAD chemosensitivity As chemosensitivity is an important risk factor for survival, we postulated that the higher chemosensitivity might indeed translate into superior EFS ... superior EFS but not OS (Figure 6) However, age, gender, VAD-sensitivity, attainment of ≥VGPR after induction therapy and achievement of ≥VGPR after auto-HSCT did not impact either EFS or OS (Table...
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Báo cáo hóa học: "DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy" pot
... University 985 Program Initiation Fund (China) Author details State Key Laboratory of Oncology in South China, Guangzhou 510060, China 2Department of Medical Oncology, Sun Yat-Sen University Cancer ... Guangzhou 510060, China 3Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China Page of Authors’ contributions KYT carried out the cytotoxicity assay and the IHC, ... relatively low in gastric cancer, due to subjectivity, the error of IHC counting could be bigger, which may influence the sensitivity and specificity when predicting treatment response, so more accurate...
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báo cáo hóa học:" Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients" pdf
... size Histological type 334 (77%) 142 (74%) 192 (79%) endometrioid clear cell serous 22 (5%) 15 (3%) (4%) (2%) 14 (6%) 11 (4%) undifferentiated 33 (8%) 20 (11%) 13 (5%) other types 31 (7%) 17 (9%) ... between survivin expression and clinicopathological variables were assessed using the chi- square test Probability of survival and diseasefree survival (DFS) were estimated using the KaplanMeier ... multivariate Cox’s proportional hazard models Tumour response to chemotherapy (probability of CR, probability of PS or HPS) was evaluated using a multivariate logistic regression model Statistical...
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báo cáo hóa học:" Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs" potx
... Prasad VR: The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type reverse transcriptase Nucleic Acids Res 1998, 26:3066-3072 Abstract ... RT was limited to positions 38249 due to the type of assay performed Sequencing of both the RT and PR genes was also employed to determine the subtypes of these viral isolates in concert with ... http://hivdb.stanford.edu/ Nucleotide genomic diversity in the RT and PR regions of the various viral isolates was compared with a consensus subtype B reference virus, LAV-1 (http://www.hiv.lanl.gov;...
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báo cáo hóa học: " F-fluoride PET: changes in uptake as a method to assess response in bone metastases from castrate-resistant prostate cancer patients treated with 223Ra-chloride (Alpharadin)" pdf
... tumour activity by measuring parameters that primarily reflect osteoblastic activity (i.e ALP and 18 F-fluoride uptake) is a temporal discordance in changes with intrinsic tumour activity Although ... may subside at a different rate than the metabolic activity of the malignant tumour tissue, or an initial increase in osteoblastic activity may occur as part of a healing response in the surrounding ... in bone clearance of tracer, is also limited in practicality These results are from a small pilot study, and the conclusions on the ability of 18F-fluoride PET to measure early response in bone...
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Báo cáo y học: "Primary Care Outcomes in Patients Treated by Nurse Practitioners or Physicians" docx
... opportunity to compare the types of providers was made possible by several practice and policy innovations at the Columbia Presbyterian Center of New York Presbyterian Hospital in New York City In ... individual providers or small group practices The providers were faculty from a university medical center, hence were not necessarily typical of those in nonacademic practice settings The patients were ... physicians were able to function equally as primary care providers The ability to this type of study, even in a setting atypical for some patients, adds significant weight to the results from prior...
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Báo cáo y học: "Brain choline concentrations may not be altered in euthymic bipolar disorder patients chronically treated with either lithium or sodium valproate" pps
... immediate family history, of psychiatric disorder For patients, diagnoses were made using DSM-IV criteria for Bipolar Disorder Type I or Type II following detailed psychiatric interview, with additional ... completed this study Of the 14 bipolar patients taking lithium, were Type I and were Type II In the valproate group, were Type I and were Type II These groups were studied both separately and together, ... and lithium-treated psychiatric patients Biol Psychiatry 1985, 20:1277-1283 Stoll AL, Cohen BM, Hanin I: Erythrocyte choline concentrations in psychiatric disorders Biol Psychiatry 1991, 29:309-321...
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Báo cáo y học: "Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept" pot
... Reumatism, the Crafoord Foundation, the Nanna Svartz foundation, and the Medical Faculty of Lund University The skilful technical assistance of Mrs Mette Lindell is appreciated References Welsing ... Swinkels HL, Kiemeney LA, van Riel PL: The relationship between disease activity, joint destruction, and functional capacity over the course of rheumatoid arthritis Arthritis Rheum 2001, 44:2009-2017 ... comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis Lancet 1994, 344:1105-1110 Moreland LW, Baumgartner SW, Schiff MH, Tindall...
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Báo cáo y học: "Circulating tumour necrosis factor-α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical respone" pot
... assessment of pain, patient's global assessment of disease activity, physician's global assessment of disease activity, the Disability Index of the Health Assessment Questionnaire, serum levels ... are summarized in Table Bioassay for circulating TNF-α bioactivity A functional assay for TNF-α activity was designed using the ability of RA synoviocytes to produce IL-6 and OPG in response to ... bioactivity and clinical response Using the ability of TNF-α to stimulate rheumatoid arthritis synoviocytes, TNF-α (5 ng/ml) was combined with 20 µl plasma per well in order to increase the sensitivity...
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Báo cáo y học: "Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs" ppsx
... genotype [31] Several authors have also proposed the use of Table IL-10 and TNFα genotypes of systemic lupus erythematosus patients stratified by treatment Treatment TNFα genotype IL-10 genotype ... producer genotype and good response to antimalarial drugs (OR 2.25, 95%CI 1.11–4.58, p = 0.024), whereas the IL-10 genotype did not show any significant association However, when combined genotypes ... producer genotypes with the most common low producers A combined two-loci model was developed, including both cytokine polymorphisms to estimate individual effects of each combined genotype, using...
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Báo cáo khoa học: "Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients" pot
... Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand, 2Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand and 3Department of Statistics, Faculty ... University, Chiang Mai, Thailand and 3Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand Chitapanarux et al Radiation Oncology 2010, 5:31 http://www.ro-journal.com/content/5/1/31 ... statistical software (version 11.5, SPSS Inc., 444 N Michigan, Chicago, Illinois, USA) Results Between January 2007 and April 2009, sixty-three patients were randomly allocated to receive lactobacillus...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... tissue complication probability (NTCP) [8,12,13] value and relative volume of lung receiving more than a threshold dose (Vdose) [7,10,14-19] Technology such as intensity-modulated radiotherapy (IMRT) ... study was funded by National Natural Science Foundation of China (30870738) We thank Drs Zhongxing Liao and Joe Y Chang of the University of Texas M D Anderson Cancer Center of Texas, USA for reviewing ... Translational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100142, China Received: 30 January 2010 Accepted: 12 May 2010 Published:...
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