creactive protein structure synthesis and function
Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc
... 2,3 and 4, lower band). The levels of mutant and wild-type MCPIP mRNAs were higher when thesevectors were co-transfected with a vector overexpress-ing IL-1b (Fig. 5, lanes 3 and 4, upper bands). ... correctregions in protein models using structural, alignment, and consensus information. Protein Sci 15, 900–913.6 Kurowski MA & Bujnicki JM (2003) GeneSilico protein structure prediction ... appear-ance of functional proteins. As reported by Kaspar and Gehrke [18] and Dinarello [19], stimulation ofmacrophages by mild stimulants (such as C5a comple-ment or some modified proteins) leads...
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Tài liệu Báo cáo khoa học: The Mycobacterium tuberculosis membrane protein Rv2560 ) biochemical and functional studies pdf
... preimmune and post-third inoculation sera against aM. tuberculosis sonicate (lanes 1, 2 and 5) and a membrane frac-tion (lanes 3 and 4). Lanes 1 and 3, absence of recognition ofM. tuberculosis proteins ... subunit-based, multiepitope, anti-TBvaccine candidate.Rv2560 is a proline- and glycine-rich transmembrane protein, and may thus be classified as a simplesequence protein (SSP). This type of sequence ... forU937 proteins specifically cross-linked with radiolabelled peptide11024. Lanes 1 and 2, U937 cells; lanes 3 and 4, HepG2 cells;lanes 1 and 3, total radiolabelled peptide binding; lanes 2 and...
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Báo cáo khoa học: Synthesis and function of ribosomal proteins – fading models and new perspectives pptx
... 1.ConclusionsIn the last few years, the study of the synthesis and function of RPs has both expanded our knowledgeS. Caldarola et al. Ribosomal protein synthesis FEBS Journal 276 (2009) 3199–3210 ª ... 2009 FEBSREVIEW ARTICLE Synthesis and function of ribosomal proteins – fadingmodels and new perspectivesSara Caldarola, Maria Chiara De Stefano, Francesco Amaldi and Fabrizio LoreniDepartment ... Novelubiquitin fusion proteins: ribosomal protein P1 and actin. J Mol Biol 328, 771–778.54 Kirschner LS & Stratakis CA (2000) Structure of thehuman ubiquitin fusion gene Uba80 (RPS27a) and oneof...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... FEBSInteraction between very-KIND Ras guanine exchangefactor and microtubule-associated protein 2, and its rolein dendrite growth – structure and function of the secondkinase noncatalytic C-lobe domainJinhong ... is a putative protein protein interaction module. Four KIND-containing proteins, Spir-2 (actin-nuclearfactor), PTPN13 (protein tyrosine phosphatase), FRMPD2 (scaffold protein) and very-KIND ... compilation ª 2011 FEBS 1655Introduction Protein protein interactions play important roles inthe molecular recognition and functional modulationbetween proteins in many signal transduction path-ways...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... dublin TLP and zebrafish TLP are found in the flex-ible portions of strands B and C that protrude towardsthe solvent and in the conformation of the long loopconnecting strands D and E [17]. ... between the loops joining standsG and H with the loops joining strands A and B, mak-ing the transthyretin tetramer a ‘dimer of dimers.’Recently, the first crystal structures of TLP fromvarious ... transthyretin-related protein family. Eur J Biochem 270, 518–532.11 Hennebry SC, Wright HM, Likic V & Richardson SJ(2006a) Structural and functional evolution of transthy-retin and transthyretin-like proteins....
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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... TET family proteins in thecontrol of DNA methylation and genome function. CG islands can also be targets for dysregulation indiseased states whereby they can become hypermethy-lated and maintained ... required for function in either T cells or mast cells.Shown below are the positions that nucleo-somes and GATA-2 occupy in unstimulatedT cells and mast cells [85].Active chromatin and DNase ... exist within CGislands which are characterized by their very high CGcontent and have an intrinsic resistance to DNA meth-ylation. CG-island promoters tend to be constitutively and ⁄ or ubiquitously...
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... HPRT and hypoxanthine. (C) PRTFDC1 and guanine. (D) HPRT and guanine.Table 2. Km and Vmaxvalues for Hx and G in the presence of 1 mM PRPP, determined using the DE-81 filter paper assay and ... [39] and ESPript [40]. Superposi-tions used in the text and figures were made using the ssmsuperposition algorithm in coot [33,41]. The coordinates and structure factors are published in the Protein ... Environment, AgriculturalSciences and Spatial Planning (to L.W. and S.E.), theSwedish Research Council (to H.E. and P.N.) and the Swedish Cancer Foundation (to H.E. and P.N.).The Structural Genomics...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... from Koehl, 1995).BODY SIZE AND SUSPENSION FEEDING 21Body SizeThe Structure and Function of Aquatic EcosystemsEdited byALAN G. HILDREWSchool of Biological and Chemical Sciences, Queen Mary, ... SIZE AND SUSPENSION FEEDING 19Body Size: The Structure and Function of Aquatic EcosystemsEcologists have long struggled to predict features of ecological systems, such asthe numbers and diversity ... important, and (ii) to compare freshwater and marine ecosystems. In Body Size: The Structure and Function of Aquatic Ecosystems,both those questions of scale and comparison among systems are very...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... (B) The DHAP binding sitewith crucial protein residues and solvent molecules engaged inligand recognition and stabilization are drawn as balls -and- sticks and spheres, respectively. The major ... ACMSD upon ligand bind-ing. The image was obtained by optimal superposition of the hA-CMSD:DHAP and PfACMSD:ligand-free structures. Protein residuesare colored in white for hACMSD and in green ... Zn2+ion and the coordinated solvent molecule areshown as magenta and cyan spheres, respectively. The strictly con-served protein residues forming the metal coordinative sphere and the ligand molecule...
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Tài liệu Báo cáo khoa học: Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium ppt
... coordinates and structure factors of thecrystal structures described in this studyhave been submitted to the Protein DataBank, and the structures have beenassigned the accession codes 2v4n and 2v4o ... survival protein SurE with metal ion and AMP. J Mol Biol 371, 123–136.11 Mura C, Katz JE, Clarke SG & Eisenberg D (2003) Structure and function of an archaeal homolog ofsurvival protein ... 2. Structure of the C2-SurE tetramer. The A to D subunits arerepresented by pink, cyan, blue and yellow, respectively. The tetra-meric interactions are between the subunits A and C, and B and...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc
... presence of the mutation and showed that no other changes were present.Expression and purification of bsSHMT and E53QbsSHMTThe expression and purification of the wild-type (bsSHMT) and the mutant enzymes ... group and contained one monomer in theasymmetric unit. Cell dimensions and details of data collec-tion are shown in Table 2. Structure solution and model buildingThe bsSHMT crystal structure ... used for thesuperposition of structures [32]. Differences between thestructures were detected visually and by calculating distancesCrystal structure of E53QbsSHMT and its complexes V. Rajaram...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... Tecnologia).References1. Davies, D.R. (1990) The structure and function of the asparticproteinases. Annu. Rev. Biophys. Biophys. Chem. 19, 189–215.2. Dunn, B.M. (2002) Structure and mechanism of the pepsin-likefamily ... Wilimowska-Pelc, A. (1985)14Purification and characterization ofaspartic proteinases from Cucumis sativus and Cucurbita maximaseeds. In Aspartic Proteinases and their Inhibitors. (Kostka, V. ed)pp. ... beinvolved in intracellular protein turnover to increase aminoacid pools for the synthesis of specific defense-relatedproteins and/ or in the defense against pathogens byhydrolyzing proteins secreted...
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