computer based methods for the prediction of chemical metabolism and biotransformation within biological organisms
Predicting Chemical Toxicity and Fate - Section 3 ppt
... LLC CHAPTER 10 Computer- Based Methods for the Prediction of Chemical Metabolism and Biotransformation within Biological Organisms Martin P Payne CONTENTS I Introduction II Structure -Metabolism Relationships ... assessment of existing chemicals and for the early screening of candidate chemicals, particularly in the agrochemical and pharmaceutical industries, in the process of high throughput screening One of the ... to the chemical determinants and can be used to predict the effect of other chemicals possessing chemical features in the same range of the modeled set of chemicals A QSARs for Individual Chemical...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
... based upon the patient remaining on therapy and achieving either low disease activity (DAS28 1.2 unit improvement in their DAS28 The PPV of the administrative data -based ... sensitivity and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the ... users and the performance characteristics of the effectiveness algorithm between biologic and DMARD treatment episodes, the data were shown throughout for the biologic users as a unique group, and...
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Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge
... Elution was performed with the same buffer at a flow rate of ml/h and ml fractions were collected The void volume of the column was determined by the elution of Blue Dextran (Pharmacia) Other analyses ... compared to the other methods The SDS-extracted polymer included a small amount of material other than protein Furthermore, the steaming- and washing-extracted polymers contained large amounts of phosphorus ... demonstrated the same mobility in both stains, suggesting that these bands were complexes of protein and saccharide These included the band corresponding to a molecular weight of 103,000 in the steaming-extracted...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt
... ABOUT THE LAW ENFORCEMENT AND CORRECTIONS STANDARDS AND TESTING PROGRAM The Law Enforcement and Corrections Standards and Testing Program is sponsored by the Office of Science and Technology of the ... Bureau of Justice Assistance, the Bureau of Justice Statistics, the Office of Juvenile Justice and Delinquency Prevention, and the Office for Victims of Crime U.S Department of Justice Office of ... by the Office of Law Enforcement Standards (OLES) of the National Institute of Standards and Technology (NIST) under the direction of Dr Alim A Fatah, Program Manager for Chemical Systems and...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf
... ABOUT THE LAW ENFORCEMENT AND CORRECTIONS STANDARDS AND TESTING PROGRAM The Law Enforcement and Corrections Standards and Testing Program is sponsored by the Office of Science and Technology of the ... Bureau of Justice Assistance, the Bureau of Justice Statistics, the Office of Juvenile Justice and Delinquency Prevention, and the Office for Victims of Crime U.S Department of Justice Office of ... by the Office of Law Enforcement Standards (OLES) of the National Institute of Standards and Technology (NIST) under the direction of Dr Alim A Fatah, Program Manager for Chemical Systems and...
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nmr methods for the investigation of structure and transport
... number of spins By linearity of the Fourier transform the direct relation between the peak integral and the number of spins of the corresponding chemical group holds for the spectrum of superposed ... expressions Qn and MCk the naturals n and k signify the index of the result and measured data vectors, respectively The latter results from the discretization of e.g kx in (2.38) For the sake of completeness, ... the scaling of the argument on index k of the measured data in reciprocal space As the sum is finite, it only represents an approximation of the delta function The position of the origin and the...
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báo cáo hóa học: " The evolution of methods for the capture of human movement leading to markerless motion capture for biomechanical applications" pptx
... improving the efficiency of troop movement During the 1950s there was a need for an improved understanding of locomotion for the treatment of World War II veterans The classic work at the University of ... University of California [5,6] provided a tremendous resource of knowledge related to the mechanics of human movement The work at the University of California formed the basis for many of the fundamental ... Journal of NeuroEngineering and Rehabilitation 2006, 3:6 the capture and analysis of human movement For example, the Weber brothers (1836) reported one of the first quantitative studies of the temporal...
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báo cáo hóa học:" Biomechanical testing of a polymer-based biomaterial for the restoration of spinal stability after nucleotomy" pptx
... destruction of the ligaments, capsules and soft tissue Soft tissue was only removed from the upper half of the cranial vertebral body and the lower half of the caudal vertebral body The upper and lower ... customized the PGA-HA biomaterial 15 CK participated in the design of the study and performed the statistical analysis 16 17 ES participated in the design and coordination of the study and helped ... wall of the annulus fibrosus Ideally, the suture penetrates the annulus close to the vertebral endplate The sutures are then fixated by surgical knots at the outer surface of the annulus Page of...
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Báo cáo hóa học: " A quantum dots and superparamagnetic nanoparticle-based method for the detection of HPV DNA" ppt
... hybridization assay on the basis of the cutoff value Detection of HPV-16 with QDs and superparamagnetic nanoparticle -based hybridization The rationale of QDs and superparamagnetic nanoparticle -based hybridization ... the cutoff value of QDs and superparamagnetic nanoparticle -based hybridization The detection procedure was described in detail in the next section (Figure 1) The cutoff value was defined as the ... Page of predenatured at 95°C for 10 min, then 55°C for 30 The particles coupled with streptavidin were added into the hybridization mixtures and incubated at 37°C for 10 and enriched in the bottom...
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Cocoa Processing Methods for the Production of High Quality Cocoa in Vietnam ppt
... presence of certain defects which may cause off-flavours and indicates the degree of fermentation of the beans which has a bearing on the flavour and quality of the beans The International Standards ... fermentation box Because of their beneficial effect on cocoa fermentation and the resultant dried cocoa quality, the practices of pod storage for 7-9 days and spreading of beans in the sun for two hours, ... rises in each of the box sizes and the heap fermentation This indicates the suitability of a range of box sizes and heap fermentations THE EFFECT OF POD STORAGE Pod storage is convenient for farmers...
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Standard Methods for the Examination of Water and Wastewater P4. end
... bias of the results depends on the bias of the analytical data applied to the nomographs and the validity of the theoretical equations and the numerical constants on which the nomographs are based ... Federation Standard Methods for the Examination of Water and Wastewater Based on the results of six operators in three laboratories, the overall and single-operator precision of this method within ... Environment Federation Standard Methods for the Examination of Water and Wastewater bromination of the phenol red occur readily If the reaction is buffered to pH 4.5 to 4.7, the color of the brominated...
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Standard Methods for the Examination of Water and Wastewater P3
... Federation Standard Methods for the Examination of Water and Wastewater Organism Plate 10900 E Selected Taxonomic References The most useful references for the nonspecialist are listed below These references ... Water Environment Federation Standard Methods for the Examination of Water and Wastewater Algae General TAYLOR, W.R 1957 Marine Algae of the Northeastern Coast of North America, 2nd ed Univ Michigan ... DAILEY, M.D., D.J REISH & J.W ANDERSON, eds 1994 Ecology of the Southern California Bight Univ California Press, Berkeley REISH, D.J 1995 Marine Life of Southern California, 2nd ed Kendall/ Hunt...
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Standard Methods for the Examination of Water and Wastewater P2
... and Wastewater Pandorina © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and ... Standard Methods for the Examination of Water and Wastewater Synedra © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods ... Methods for the Examination of Water and Wastewater Ceratium © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for...
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Standard Methods for the Examination of Water and Wastewater P1
... 12] The atomic weights of many elements are not invariant but depend on the origin and treatment of the material The standard values of Ar(E) and the uncertainties (in parentheses, following the ... Federation Standard Methods for the Examination of Water and Wastewater Phone: (303) 794-7711 Fax: (303) 794-7310 Water Environment Federation (WEF) The Water Environment Federation is a not -for- profit ... worldwide Through educational and technical information programs, AWWA promotes the improvement of the quality and quantity of the drinking water supply Contact information: AWWA 6666 West Quincy...
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Báo cáo khoa học: "Comparison of Diagnostic Methods for the Detection of Parasites in Fish" pdf
... Comparison of Diagnostic Methods for the Detection of Parasites in Fish and disadvantages, depending on the purpose and target of study For parasitological investigation, the classical methods (the ... normal PCR reaction of 50 µl volume (25µl of master mix, Comparison of Diagnostic Methods for the Detection of Parasites in Fish 2µl of each primer, or µl of template and 18 or 20 µl of water) - Polymerase ... classification of parasites, the diagnosis of infections, the epidemiology of parasites, the analysis of population genetic structures, gene expression and organization, the study of drug resistance and...
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Báo cáo khoa học: " Effective methods for the production of immunoglobulin Y using immunogens of Bordetella bronchiseptica , Pasteurella multocida and Actinobacillus pleuropneumoniae" docx
... volume of PBS The homogenized egg yolk was then mixed with two volumes of chloroform and incubated for hrs at room temperature After this incubation, the supernatant was collected To compare the ... at and weeks in sera and egg yolks, respectively, after the first injection (Fig and 2) The titers of the vaccinated groups were three times higher than those of the control group Antibody profiles ... components of the causative agents of AR, B bronchiseptica and P multocida 4:D, and animals were immunized using different methods (Table 1) Results from the groups suggest that the LPS of the killed...
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Báo cáo khoa học: " Comparison of two sap flow methods for the estimation of tree transpiration" ppt
... transpiration The combination of the two methods seems possible in the same experiment The heat balance for the small trunks, and transpiration calculation for small periods and Granier’s method for the ... functioning of each method was not deteriorated by the other The relationship obtained with the comparison of the two methods over the whole period (n 589) is presented in figure The slope of the regression ... from thermopile meathermopile was composed of surements The four thermojunctions in series, located on either side of a mm thick rubber The sheath conductance of the gauge is calculated during the...
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Báo cáo sinh học: "Use of sib-pair linkage methods for the estimation of the genetic variance at a quantitative trait locus" pps
... estimator of the QTL variance Whether the bias on the size of the biasing factor not, it depends in the range of realistic values for O t shows the value ofk as a function of for different values of ... to examine the power and properties of the method genetic MATERIALS AND METHODS Theory Haseman and Elston’s test (1972) is based on the idea that the difference in the performance of full-sibs ... overestimation of this parameter = = a q Q9cannot RESULTS Power of the methods Table II shows the power of the methods of estimation for all simulated variants For a QTL effect of 40, the power is low for...
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Báo cáo y học: "An alternative methodology for the prediction of adherence to anti HIV treatment" ppt
... purposes) AIDS Research and Therapy 2009, 6:9 adherence/non-adherence' groupings based upon the rate of change of VL and the presence of mutation Testing the hypothesis The preliminary work relating ... [Karolinska], Rolf Kaiser [Arevir] for their data and Yardena Peres [IBM, Israel] for the integration of these data; all other partners within the EuResist project for input and discussion at various ... physicians The utilisation of VL data, with knowledge of the presence (or lack) of drug resistant mutations, should allow clinicians to form a more accurate picture of the adherence levels of their...
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báo cáo khoa học: " Social networks, work and network-based resources for the management of long-term conditions: a framework and study protocol for developing self-care support" potx
... between the Greater Manchester NHS Trusts and the University of Manchester and is part of the National Institute for Health Research The authors are members of the Patient Theme of CLAHRC for Greater ... a sense of normality and well-being for themselves and for others (see Figure patient-focused outcomes) 2) Illness management and types of work The scope of the potential involvement of different ... translating research and implementation into practice [5], forms the basis of the Collaboration for Leadership in Applied Health Research and Care for Greater Manchester (CLAHRC) The focus of the research...
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