... early managementofpatientswith a head injury, 14 followed in 1999 by the Galasko report from the Royal College of Surgeons.15 SIGN published SIGN 46: Early managementofpatientswith a head injury ... over 65 years of age.45,46 1++ 2+ 13 Early managementofpatientswith a head injury Mechanism ofinjury was associated with intracranial injury, with ORs of 1.65 and 2.8 reported.39,47 In children, ... for patientswith minor head injury Entry criteria were loss of consciousness or post -traumatic amnesia following a head injury, in patientswith a GCS of 13-15 The study excluded all patients with...
... rFVIIa in trauma patients Thus, TE events occurred in 4% (6 of 138) of the placebo-treated patients as compared with 4% (6 of 139) of the rFVIIa-treated patients The incidence of fatal TE events ... accurate diagnosis and severity assessment of the head injury in the majority of these patients Therefore, to identify patientswith a TBI component of their injury, we were obliged to perform a post ... Six of these patients had additional polytrauma The outcome of these patients was poor and 15 of 20 patients died The authors attributed this high mortality rate to the severity of brain injury...
... culture in the CSF eSOFA pre: value of the Sepsis related Organ-Failure Assessment (SOFA) score before the beginning of the barbiturate coma fSOFA maximum: maximum value of the SOFA during the barbiturate ... Thoracic injury 0.13 Abdominal injury 0.34 Extremities injury 0.20 Diffuse injury without brain swelling 12 0.046 Diffuse bilateral brain swelling 12 Diffuse unilateral brain swelling with midline ... by the Traumatic Coma Data Bank [8] We also recorded findings of CTs conducted before inclusion of the patients in the study The CT findings on inclusion were regarded to be the worst of the...
... 42 ANNEXES 43 MANAGEMENTofpatientswith dementia 44 ANNEXES 45 MANAGEMENTofpatientswith dementia 46 ANNEXES 47 MANAGEMENTofpatientswith dementia Annex Short form of the Informant Questionnaire ... than in people with Alzheimer’s disease MANAGEMENTofpatientswith dementia Dementia with Lewy bodies Characteristic features of dementia with Lewy bodies (DLB) are fluctuation of awareness ... limited number of behavioural problems in patientswith mild to moderate dementia.97,98,101-105 1++ 1+ One small study of augmentation of perphenazine in patientswith moderate dementia, with either...
... 1994; Moffatt et al 1994; Simon et al 1994) Strength of evidence IAssessment ofPatientswith Leg Ulcers The managementofpatientswith venous leg ulcers Assessment 2.1 Assessment ofPatientswith ... also fall with age Strength of evidence II 10 The managementofpatientswith venous leg ulcers Assessment 2.2 ManagementofPatientswith Venous Leg Ulcers The records show that patientswith venous ... photocopy of each form before sending it 24 The managementofpatientswith venous leg ulcers Appendix 2: Audit Form The managementofpatientswith venous leg ulcers Notes 25 26 The managementof patients...
... SIGN 119 Managementofpatientswith stroke: identification and managementof dysphagia6 and SIGN 108 Managementofpatientswith stroke or TIA: assessment, investigation, immediate management ... stroke patients and their families and liaised with services with the aim of improving aspects of participation and quality of life for patientswith stroke and/or their carers The backgrounds of ... an update of SIGN 64 Managementofpatientswith stroke: rehabilitation, prevention and managementof complications, and discharge planning and supersedes it Since the publication of SIGN 64...
... as offering the best compromise between accuracy of staging and containment of morbidity 17 MANAGEMENTOFPATIENTSWITH LUNG CANCER 6.2.5 RESECTION IN PATIENTSWITH STAGE IIIA NSCLC A number of ... for patientswith stage 1A lung cancer and 38-65% for patientswith stage 1B lung cancer Surgery gives the highest chance of cure for patientswith stage I and II lung cancer D 6.2.2 Patientswith ... palliative radiotherapy with single fractions of 8Gy 23 MANAGEMENTOFPATIENTSWITH LUNG CANCER Chemotherapy The greatest change in the managementof lung cancer since the publication of the original...
... days of drug dispensed based on the assessment schedule Patientswith values between 80% and 100% were considered to be treatment compliant Of the 153 patients enrolled in the study, 106 patients ... mg/day Of the 153 patients enrolled in the study, 106 patients (69.2%) were compliant with treatment During the 12-week switching period, no patients received diphenhydramine and five patients ... demonstrated the effectiveness of aripiprazole compared with standard -of- care treatment in outpatient-treated patientswith schizophrenia, especially in the areas of symptom improvement, clinical...
... in patientswith SMI were also evaluated, along with current Page of 10 evidence on how improvements in the managementof the CVD risk factors may impact SMI patients mortality and quality of ... in individuals with SMI in the community, 29% of men and almost 60% of women with SMI were obese [51] The prevalence of obesity in patientswith SMI is equal or higher than that of the general ... 60% ofpatientswith depression and post -traumatic- stress disorder are smokers, while in patientswith schizophrenia the prevalence of smoking can be as high as 65% to 90% [66] Relative risk of...
... impact of non-operative managementof advanced CRC in an unselected, consecutive series ofpatients presenting with newly diagnosed disease It reviews and compares the outcomes ofpatientswith ... formation in patients presenting with malignant large bowel obstruction One of the concerns in managing patientswith surgically incurable CRC without resection of the primary tumour is the risk of the ... score of operated patients, stoma rates in operated patients and the indications for surgery in emergency patientsPatients deemed surgically incurable at presentation were studied Patients with...
... Effect of prone positioning on the survival ofpatientswith acute respiratory failure N Engl J Med 2001, 345:568-573 The ARDS Network: Ventilation with lower tidal volumes as compared with traditional ... 40–49 31–40 0–31 Quartiles of SAPS II Proning may benefit the most seriously ill subset ofpatientswith acute respiratory distress syndrome Those in the quartile with the highest Simplified ... that withholding the option to prone was unethical, based on their early experience Thirdly, a post hoc analysis of the data indicated a marked mortality benefit with proning in the subset of patients...
... led to a relative risk reduction of almost 30% in patientswith septic shock [9] The survival benefit of combination therapy was significant only in patientswith blunted response to ACTH stimulation ... effects of catecholamine dysfunction and refractory hypotension [5] Downregulation of catecholamine receptors occurs with prolonged use of exogenous catecholamines and this may be reversed with ... similar resistance because of poor experiences with identical drugs given in higher doses [18] Levels of cortisol and responsiveness to ACTH stimulation in patientswith sepsis vary considerably...
... the rate of infection of pancreatic necrosis [4] Pooling of the data from these 183 patients by Bosscha and colleagues in a meta-analysis resulted in a group of 95 patients treated with prophylactic ... to acute pancreatitis Con: No, antibiotics are not important in the managementofpatientswith pancreatitis with evidence of pancreatic necrosis Lorne H Blackbourne and Stephen M Cohn Limiting ... mortality (64%) compared with those patients without Candida (19%, P < 0.01) Certainly, critically ill patients developing superinfections tend to be those with more severe disease, with longer antibiotic...
... mind that most patientswith acute respiratory distress syndrome still die of multiple organ failure and not of hypoxemia In this regard, PPV is now used (and normalized by the use of fluid) routinely ... outcome ofpatients undergoing high-risk surgery PPV as a tool to track changes in contractility? Determinants of pulse pressure variation Pulse pressure variation (PPV) is a marker of the position ... Michard et al Figure Patients who have reached the plateau of the Frank–Starling relationship can be identified as patients in whom PPV is low The clinical and intraoperative goal of ‘maximizing stroke...
... http://ccforum.com/content/14/2/307 Commentary Traumatic brain injury (TBI) is devastating with catastrophic consequences Early recognition ofinjury and prompt delivery of focused care of the traumatic brain injured ... known to be associated with increased mortality from traumatic brain injury Analyses were conducted in all patients and in subgroups according to severity oftraumatic brain injury The authors found ... Assistant Professor, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA 4Professor, Department of Critical Care Medicine, University of Pittsburgh...
... 1-month mortality ofpatients Serial change in plasma resistin level in patientswith TBI Correlations of plasma resistin level with GCS scores After TBI, plasma resistin level in patients increased ... proportion ofpatients in the nonsurvival group suffered from hyperglycemia (P = 0.003), had CT classification of The predictive significance of plasma resistin level for 1month mortality ofpatients ... patients had the presence oftraumatic subarachnoid hemorrhage After admission, 21 (22.3%) patients presented with neurological deterioration In the first 24 hours, 40 (42.6%) patients underwent intracranial...
... characteristics ofpatients within their respective subgroups As expected, patientswith TBI had sustained a higher overall magnitude ofinjury as compared to patients without TBI (P < 0.001) Patients without ... whether TBI patients have the same association of improved survival with a more balanced transfusion of FFP and pRBCs In patientswith TBI, there is a component of local tissue release of thromboplastin ... into patientswith TBI (Abbreviated Injury Scale (AIS) score, head ≥3) and patients without TBI (AIS score, head
... 1) patientswith severe dementia or aphasia; 2) patients whose visual or hearing impairment does not allow possibility of interaction with the system; 3) patientswith hemispatial neglect; 4) patients ... of the patients, achieving a system that reinforces the motivation of the patients during the rehabilitative process and providing the therapists with objective data of the evolution of the patients ... consisted of 11 men and women ranging from 16 to 76 years old (47.3 ± 17.8) and a mean chronicity of 570.9 ± 313.2 days Etiology of acquired brain injury in this group ofpatients included severe traumatic...
... association of BNP levels with RV dilatation and with patient outcomes (mortality) in patientswith ALI Although BNP levels were elevated in patientswith ALI, there was no association with RV dilatation ... levels in patientswith ALI are caused by RV strain In patientswith isolated RV dysfunction due to variety of conditions, BNP levels have been shown to be elevated For example, patientswith chronic ... compared withpatientswith chronic respiratory failure without cor pulmonale or controls [32,33] In patientswith idiopathic pulmonary hypertension, BNP was elevated and was correlated with the...
... and all patients gave written informed consent All OA patients fulfilled the criteria of the American College of Rheumatology for the classification of OA [24] Isolation and culture of synovial ... 23/53 OA patients DREAM mRNA was significantly reduced by 63% in PBMCs from OA patients, with a pain score on the VAS (0 to 100) of greater than 40 (n = 14) compared with healthy controls OA patients ... compared with healthy controls (❍) and with OA patientswith a low pain score (VAS score of less than or equal to 40; ∇) No significant differences were observed between healthy controls and OA patients...